ES2481565T3 - Indicador visual para un aparato para dispensar medicamentos en aerosol y sistema correspondiente - Google Patents

Indicador visual para un aparato para dispensar medicamentos en aerosol y sistema correspondiente Download PDF

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Publication number
ES2481565T3
ES2481565T3 ES03725467.9T ES03725467T ES2481565T3 ES 2481565 T3 ES2481565 T3 ES 2481565T3 ES 03725467 T ES03725467 T ES 03725467T ES 2481565 T3 ES2481565 T3 ES 2481565T3
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ES
Spain
Prior art keywords
substance
interface
opening
flow indicator
path
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES03725467.9T
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English (en)
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ES2481565T1 (es
Inventor
Sarah Bruce
James N. Schmidt
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Trudell Medical International
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Trudell Medical International
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0013Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0018Details of inhalators; Constructional features thereof with exhalation check valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06Respiratory or anaesthetic masks
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06Respiratory or anaesthetic masks
    • A61M16/0605Means for improving the adaptation of the mask to the patient
    • A61M16/0616Means for improving the adaptation of the mask to the patient with face sealing means comprising a flap or membrane projecting inwards, such that sealing increases with increasing inhalation gas pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20Valves specially adapted to medical respiratory devices
    • A61M16/208Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00Methods of manufacture, assembly or production
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49826Assembling or joining

Abstract

Sistema dispensador que comprende: una camara que contiene una sustancia en un volumen de espacio interior formado dentro de dicha camara; una abertura que recibe dicha sustancia ubicada en dicho volumen de espacio e introduce dicha sustancia a una trayectoria curso abajo a lo largo de la cual fluye principalmente dicha sustancia; una interfaz que recibe dicha sustancia desde dicha abertura, comprendiendo dicha interfaz una mirilla que impide sustancialmente que gases y sustancias de la atm6sfera no ambientales escapen de la misma y permite la visualizacion de una parte interna de dicha interfaz; y un indicador de flujo que esta posicionado en el interior de dicha interfaz con el fin de verla a traves de dicha mirilla y esta posicionado para no interferir substancialmente con un flujo de dicha substancia a lo largo de la citada trayectoria.

Description

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apropiada con el usuario. El paciente o cuidador presiona entonces el depósito de pMDI dentro del adaptador del pMDI 106 unido a la pieza posterior 114 situada en el extremo posterior del alojamiento de la cámara 108, lo que provoca que el medicamento sea dispensado en forma de aerosol a la abertura 112 de la manera que se ha descrito anteriormente.
En el momento de presionar el depósito de pMDI, o justo después hacerlo, el paciente inhala. Durante una inhalación correcta, el indicador visual de flujo 138 girará hacia adelante, en respuesta a la presión de inhalación, un ángulo  entre 25º y 45º, y preferiblemente 45º, y se sellará contra una superficie 162 sobre el adaptador 140, 140', tal como se muestra en las figuras 3 y 33-34. El ángulo  puede variar para tener en cuenta los atributos del paciente, es decir, niño y bebé. Hay que tener en cuenta que el indicador visual de flujo 138 tiene una resistencia mínima, debido a su tamaño y forma, y responderá a volúmenes tidales pequeños, lo que es ideal para bebés (volumen tidal de aproximadamente 50 cc, caudal de aproximadamente 5 lpm) y niños pequeños (volumen tidal que oscila de aproximadamente 150 a 250 cc, caudal de aproximadamente 12 Ipm). El movimiento del indicador visual de flujo 138, 138' contra la superficie 162 crea una junta de estanqueidad que impide la entrada de aire ambiente. Un cuidador que dirige su atención a la zona de la mirilla 154, 154' podrá ver el movimiento del indicador de flujo 138, 138' a medida que se forma la junta de estanqueidad y, de este modo, se dará cuenta de que se está produciendo la inhalación o que ésta se ha producido. También durante la inhalación, la válvula de pico de pato 132 se abrirá permitiendo así que el medicamento en aerosol salga del alojamiento de la cámara 108 y se introduzca por la abertura 112 hacia una trayectoria curso abajo a lo largo de la cual fluye el medicamento, de manera que eventualmente será inhalado por el paciente. Tal como se muestra en las figuras 2 y 31-34, el indicador de flujo 138, 138' queda colocado encima de la válvula de pico de pato 132 y fuera de la periferia de la abertura 112 y, por lo tanto, queda fuera de la trayectoria de dispensación del medicamento y, de este modo, no compromete el suministro del medicamento. Hay que tener en cuenta que la introducción del medicamento hacia la trayectoria a través de la abertura 112 puede producirse por cualquier fuerza externa o interna.
Una vez que el paciente exhala o deja de inhalar, el indicador de flujo 138, 138' girará de nuevo hacia su posición vertical original hasta que se acopla al tope 117, tal como se muestra en las figuras 31-32. La elasticidad de los indicadores 138, 138' hace que el indicador gire o se incline hacia la posición de reposo. Una vez más, un cuidador que dirige su atención hacia la zona de la mirilla 154, 154' podrá ver el movimiento de retorno del indicador de flujo 138, 138' y, de este modo, se dará cuenta de que se ha producido la exhalación. Además de alertar al cuidador de que la inhalación o exhalación se está produciendo o se ha producido, el movimiento del indicador de flujo da la confianza al cuidador de que, cuando la interfaz de paciente incluye una máscara, entre la cara del paciente y la máscara 144 se forma un sellado adecuado.
Hay que tener en cuenta que el indicador de flujo 138, 138' proporciona una trayectoria que está en contacto hidráulico con el aire ambiente situado dentro de la zona de la mirilla 154, 154' hacia atrás del indicador de flujo 138, 138'. La trayectoria incluye una abertura posterior o una abertura formada en la parte superior posterior de la zona de la mirilla 154, 154', de manera que el indicador de flujo 138, 138' se extrae del tope. Sin embargo, el indicador de flujo 138, 138' queda sellado contra la superficie 162 para evitar el arrastre de aire ambiente, tal como se ha descrito anteriormente.
La trayectoria principal para los gases exhalados es a través de la válvula de exhalación 142 situada en la máscara 144, tal como se muestra en la figura 30. En particular, el tope 117 y el indicador de flujo 138, 138' se extienden para bloquear sustancialmente todos los gases exhalados evitando que salgan a través de la mirilla, a la vez que se permite que el aire ambiente fluya. Del mismo modo, el tope 117 y el indicador de flujo 138, 138', que queda alineado contra la superficie 162 tras la inhalación, bloquean sustancialmente la sustancia dispensada evitando que salga del sistema de suministro a través de la zona de la mirilla. En consecuencia, el tope 117 y el indicador de flujo 138, 138' evitan substancialmente que gases y sustancias no ambientales salgan del sistema de suministro a través de la zona de la mirilla.
En la figura 35 se muestra una realización alternativa de un sistema para dispensar un aerosol. El sistema para dispensar un aerosol 200 es el mismo que el sistema para dispensar un aerosol 100 de las figuras 1-11, 16-21 y 2529, excepto en que la cámara de retención y la interfaz de paciente han sido alteradas tal como se muestra en los dibujos y tal como se describe aquí. Por consiguiente, los mismos elementos conservarán las mismas referencias. Teniendo esto en cuenta, la cámara o conducto de retención 202 tiene una pieza posterior 114 unida a un extremo posterior del alojamiento de cámara 108. Una abertura de la pieza trasera 114 recibe un extremo de descarga de un adaptador (no mostrado) que aloja el depósito de pMDI. La cámara de retención 202 incluye, además, un disco de retención 216 que está unido de manera solidaria a un extremo anterior del alojamiento de la cámara cilíndrica 108. El disco de retención 216 incluye un anillo anular 218 que rodea una abertura 220. Ocho apéndices lineales 222 se extienden hacia el interior desde el anillo anular 218 y se encuentran en un núcleo central 223. El anillo anular 218, los apéndices 222 y el núcleo central 223 definen una zona de abertura de inhalación 226 que incluye ocho aberturas. El tamaño, forma y número de las aberturas pueden variar dependiendo del medicamento y/o propelente utilizado.
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Claims (1)

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ES03725467.9T 2002-05-21 2003-05-16 Indicador visual para un aparato para dispensar medicamentos en aerosol y sistema correspondiente Expired - Lifetime ES2481565T3 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38222702P 2002-05-21 2002-05-21
US382227P 2002-05-21
US431325 2003-05-07
US10/431,325 US6904908B2 (en) 2002-05-21 2003-05-07 Visual indicator for an aerosol medication delivery apparatus and system
PCT/IB2003/001904 WO2003097142A1 (en) 2002-05-21 2003-05-16 Visual indicator for an aerosol medication delivery apparatus and system

Publications (2)

Publication Number Publication Date
ES2481565T1 ES2481565T1 (es) 2014-07-31
ES2481565T3 true ES2481565T3 (es) 2015-03-24

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ES03725467.9T Expired - Lifetime ES2481565T3 (es) 2002-05-21 2003-05-16 Indicador visual para un aparato para dispensar medicamentos en aerosol y sistema correspondiente

Country Status (10)

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US (7) US6904908B2 (es)
EP (2) EP2402049B1 (es)
JP (1) JP4485351B2 (es)
CN (2) CN103041481B (es)
AU (2) AU2003227999C1 (es)
CA (4) CA2849545C (es)
ES (1) ES2481565T3 (es)
MX (1) MXPA04011575A (es)
WO (1) WO2003097142A1 (es)
ZA (1) ZA200409957B (es)

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