GB1017032A - Aerosol compositions - Google Patents

Aerosol compositions

Info

Publication number
GB1017032A
GB1017032A GB4916263A GB4916263A GB1017032A GB 1017032 A GB1017032 A GB 1017032A GB 4916263 A GB4916263 A GB 4916263A GB 4916263 A GB4916263 A GB 4916263A GB 1017032 A GB1017032 A GB 1017032A
Authority
GB
United Kingdom
Prior art keywords
alkaloid
nicotine
aerosol
substitute
lobeline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4916263A
Inventor
Sidney Samuel Hart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AEROSMOKE Ltd
Original Assignee
AEROSMOKE Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AEROSMOKE Ltd filed Critical AEROSMOKE Ltd
Priority to GB4916263A priority Critical patent/GB1017032A/en
Priority to CH1602564A priority patent/CH452119A/en
Priority to DE19641467752 priority patent/DE1467752A1/en
Publication of GB1017032A publication Critical patent/GB1017032A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0086—Inhalation chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/28—Nozzles, nozzle fittings or accessories specially adapted therefor
    • B65D83/30—Nozzles, nozzle fittings or accessories specially adapted therefor for guiding the flow of spray, e.g. funnels, hoods
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/75—Aerosol containers not provided for in groups B65D83/16 - B65D83/74
    • B65D83/752—Aerosol containers not provided for in groups B65D83/16 - B65D83/74 characterised by the use of specific products or propellants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

An appliance for reducing the tendency to smoke tobacco comprises an aerosol dispenser of the type which delivers a fixed amount of aerosol composition at each operation and which contains as an anti-smoking composition an alkaloid of the kind which acts as a substitute for nicotine by at least partly satisfying the craving therefor, uniformly dispersed in an aerosol propellant vehicle, the said fixed amount and the concentration of the alkaloid in the composition being such that from 0.05 to 0.3 mg. of the alkaloid reckoned as lobeline hydrochloride on an efficacy basis is delivered at each operation of the dispenser. The preferred alkaloid is lobeline, as the hydrochlorides; nicotine and socratine may also be present. Suitable propellants include the fluorinated and chloro fluorinated hydrocarbons. Co-solvents such as alcohol, chloroform and propylene glycol, and anti-oxidants such as ascorbic acid, a -glucoascorbic acid, a -isoascorbic acid, sodium formaldehyde sulphoxylate, sodium thioglycolate, the tocophenols or sodium bisulphite may also be included.ALSO:A substitute for smoking comprises an aerosol composition containing an alkaloid such as lobeline which acts as a nicotine substitute when inhaled. Nicotine and socratin may also be included.
GB4916263A 1963-12-12 1963-12-12 Aerosol compositions Expired GB1017032A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB4916263A GB1017032A (en) 1963-12-12 1963-12-12 Aerosol compositions
CH1602564A CH452119A (en) 1963-12-12 1964-12-11 Apparatus dispensing a product capable of reducing the need to smoke tobacco
DE19641467752 DE1467752A1 (en) 1963-12-12 1964-12-11 Device suitable for reducing addiction to tobacco smoking

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4916263A GB1017032A (en) 1963-12-12 1963-12-12 Aerosol compositions

Publications (1)

Publication Number Publication Date
GB1017032A true GB1017032A (en) 1966-01-12

Family

ID=10451393

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4916263A Expired GB1017032A (en) 1963-12-12 1963-12-12 Aerosol compositions

Country Status (3)

Country Link
CH (1) CH452119A (en)
DE (1) DE1467752A1 (en)
GB (1) GB1017032A (en)

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009667A1 (en) * 1978-09-11 1980-04-16 Michael T. Dr. Newhouse Inhalation device
EP0015247A1 (en) * 1979-02-16 1980-09-03 Aktiebolaget DRACO An aerosol inhalation device
GB2195544A (en) * 1986-08-04 1988-04-13 Universal Precision Moulders L Inhaler
WO1995011679A1 (en) * 1993-10-28 1995-05-04 Dynagen, Inc. Use of lobeline for the treatment of nicotine withdrawal
US5414005A (en) * 1993-10-28 1995-05-09 Dynagen, Inc. Methods and articles of manufacture for the treatment of nicotine withdrawal and as an aid in smoking cessation
US5427089A (en) * 1989-04-17 1995-06-27 Glaxo Group Limited Valved auxiliary device for use with aerosol container
US5780051A (en) * 1992-04-02 1998-07-14 Dynagen, Inc. Methods and articles of manufacture for nicotine cessation and monitoring nicotine use
US6293279B1 (en) 1997-09-26 2001-09-25 Trudell Medical International Aerosol medication delivery apparatus and system
US6345617B1 (en) 1997-09-26 2002-02-12 1263152 Ontario Inc. Aerosol medication delivery apparatus and system
US6431874B1 (en) 1999-10-27 2002-08-13 Goen Corporation Stop smoking method and composition
WO2005053444A1 (en) * 2003-12-05 2005-06-16 Lts Lohmann Therapie-Systeme Ag Inhaler for basic pharmaceutical agents and method for production thereof
FR2873584A1 (en) * 2004-08-02 2006-02-03 Jean Jacques Hubinois System of nicotine inhaler, useful to release nicotine, comprises pressurized compartment, oral inhalation chamber and diffusion nozzle
WO2009109733A1 (en) * 2008-03-04 2009-09-11 No Climb Products Limited Apparatus for control of the distance between an aerosol dispenser and the target at which it may be directed
US8074641B2 (en) 2002-05-02 2011-12-13 Pre Holdings, Inc. Aerosol medication inhalation system
USRE43174E1 (en) 2000-04-11 2012-02-14 Trudell Medical International Aerosol delivery apparatus
WO2014033437A2 (en) * 2012-08-28 2014-03-06 Kind Consumer Limited Nicotine composition
WO2017046593A2 (en) * 2015-09-18 2017-03-23 Kind Consumer Limited An inhalable composition and an inhaler
US9700689B2 (en) 2002-05-21 2017-07-11 Trudell Medical International Medication delivery apparatus and system and methods for the use and assembly thereof
US20180110261A1 (en) * 2013-03-26 2018-04-26 Kind Consumer Limited Pressurised refill canister with an outlet valve
US10441734B2 (en) 2012-08-28 2019-10-15 Kind Consumer Limited Inhaler

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1217890B (en) * 1988-06-22 1990-03-30 Chiesi Farma Spa DOSED AEROSOL INHALATION DEVICE
GB0905840D0 (en) * 2009-04-06 2009-05-20 Sagentia Ltd Apparatus and methods

Cited By (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009667A1 (en) * 1978-09-11 1980-04-16 Michael T. Dr. Newhouse Inhalation device
EP0015247A1 (en) * 1979-02-16 1980-09-03 Aktiebolaget DRACO An aerosol inhalation device
DK153595B (en) * 1979-02-16 1988-08-01 Draco Ab Aerosol inhalation UNIT
GB2195544A (en) * 1986-08-04 1988-04-13 Universal Precision Moulders L Inhaler
US5427089A (en) * 1989-04-17 1995-06-27 Glaxo Group Limited Valved auxiliary device for use with aerosol container
US5780051A (en) * 1992-04-02 1998-07-14 Dynagen, Inc. Methods and articles of manufacture for nicotine cessation and monitoring nicotine use
WO1995011679A1 (en) * 1993-10-28 1995-05-04 Dynagen, Inc. Use of lobeline for the treatment of nicotine withdrawal
WO1995011678A1 (en) * 1993-10-28 1995-05-04 Dynagen, Inc. Use of nicotine substitutes for the treatment of nicotine withdrawal
US5414005A (en) * 1993-10-28 1995-05-09 Dynagen, Inc. Methods and articles of manufacture for the treatment of nicotine withdrawal and as an aid in smoking cessation
US6293279B1 (en) 1997-09-26 2001-09-25 Trudell Medical International Aerosol medication delivery apparatus and system
US6345617B1 (en) 1997-09-26 2002-02-12 1263152 Ontario Inc. Aerosol medication delivery apparatus and system
US6431874B1 (en) 1999-10-27 2002-08-13 Goen Corporation Stop smoking method and composition
USRE46050E1 (en) 2000-04-11 2016-07-05 Trudell Medical International Aerosol delivery apparatus
USRE43174E1 (en) 2000-04-11 2012-02-14 Trudell Medical International Aerosol delivery apparatus
USRE45068E1 (en) 2000-04-11 2014-08-12 Trudell Medical International Aerosol delivery apparatus
US8973571B1 (en) 2002-05-02 2015-03-10 Pre Holding, Inc. Aerosol medication inhalation system
US8074641B2 (en) 2002-05-02 2011-12-13 Pre Holdings, Inc. Aerosol medication inhalation system
US8459252B2 (en) 2002-05-02 2013-06-11 Pari Innovative Manufacturers, Inc. Aerosol medication inhalation system
US9308335B2 (en) 2002-05-02 2016-04-12 Pre Holding, Inc. Aerosol medication inhalation system
US10881816B2 (en) 2002-05-21 2021-01-05 Trudell Medical International Medication delivery apparatus and system and methods for the use and assembly thereof
US9814849B2 (en) 2002-05-21 2017-11-14 Trudell Medical International Medication delivery apparatus and system and methods for the use and assembly thereof
US9700689B2 (en) 2002-05-21 2017-07-11 Trudell Medical International Medication delivery apparatus and system and methods for the use and assembly thereof
WO2005053444A1 (en) * 2003-12-05 2005-06-16 Lts Lohmann Therapie-Systeme Ag Inhaler for basic pharmaceutical agents and method for production thereof
FR2873584A1 (en) * 2004-08-02 2006-02-03 Jean Jacques Hubinois System of nicotine inhaler, useful to release nicotine, comprises pressurized compartment, oral inhalation chamber and diffusion nozzle
CN101965302B (en) * 2008-03-04 2013-10-23 诺-克莱姆产品有限公司 Apparatus for control of distance between aerosol dispenser and target at which it may be directed
WO2009109733A1 (en) * 2008-03-04 2009-09-11 No Climb Products Limited Apparatus for control of the distance between an aerosol dispenser and the target at which it may be directed
WO2014033437A2 (en) * 2012-08-28 2014-03-06 Kind Consumer Limited Nicotine composition
JP2015527071A (en) * 2012-08-28 2015-09-17 カインド・コンシューマー・リミテッドＫｉｎｄ Ｃｏｎｓｕｍｅｒ Ｌｉｍｉｔｅｄ Nicotine composition
US9655890B2 (en) 2012-08-28 2017-05-23 Kind Consumer Limited Nicotine composition
CN104768406A (en) * 2012-08-28 2015-07-08 亲切消费者有限公司 Nicotine composition
KR20150046318A (en) * 2012-08-28 2015-04-29 카인드 컨슈머 리미티드 Nicotine Composition
CN104768406B (en) * 2012-08-28 2018-11-16 亲切消费者有限公司 nicotine composition
AU2013308229B2 (en) * 2012-08-28 2019-05-09 Kind Consumer Limited Nicotine composition
US10441734B2 (en) 2012-08-28 2019-10-15 Kind Consumer Limited Inhaler
WO2014033437A3 (en) * 2012-08-28 2014-06-26 Kind Consumer Limited Nicotine composition
KR102256326B1 (en) * 2012-08-28 2021-05-26 카인드 컨슈머 리미티드 Nicotine Composition
US20180110261A1 (en) * 2013-03-26 2018-04-26 Kind Consumer Limited Pressurised refill canister with an outlet valve
WO2017046593A2 (en) * 2015-09-18 2017-03-23 Kind Consumer Limited An inhalable composition and an inhaler
WO2017046593A3 (en) * 2015-09-18 2017-04-27 Kind Consumer Limited An inhalable composition and an inhaler

Also Published As

Publication number Publication date
CH452119A (en) 1968-05-31
DE1467752A1 (en) 1968-12-12

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