WO2017046593A3 - An inhalable composition and an inhaler - Google Patents

An inhalable composition and an inhaler Download PDF

Info

Publication number
WO2017046593A3
WO2017046593A3 PCT/GB2016/052885 GB2016052885W WO2017046593A3 WO 2017046593 A3 WO2017046593 A3 WO 2017046593A3 GB 2016052885 W GB2016052885 W GB 2016052885W WO 2017046593 A3 WO2017046593 A3 WO 2017046593A3
Authority
WO
WIPO (PCT)
Prior art keywords
inhaler
composition
inhalable composition
propellant
heater
Prior art date
Application number
PCT/GB2016/052885
Other languages
French (fr)
Other versions
WO2017046593A2 (en
Inventor
Alex Hearn
Ritika Gupta
Original Assignee
Kind Consumer Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kind Consumer Limited filed Critical Kind Consumer Limited
Priority to EP16770320.6A priority Critical patent/EP3349605A2/en
Priority to CN201680066605.8A priority patent/CN108348013A/en
Publication of WO2017046593A2 publication Critical patent/WO2017046593A2/en
Publication of WO2017046593A3 publication Critical patent/WO2017046593A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241—Extraction of specific substances
    • A24B15/243—Nicotine
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F15/00—Receptacles or boxes specially adapted for cigars, cigarettes, simulated smoking devices or cigarettes therefor
    • A24F15/01—Receptacles or boxes specially adapted for cigars, cigarettes, simulated smoking devices or cigarettes therefor specially adapted for simulated smoking devices or cigarettes therefor
    • A24F15/015—Receptacles or boxes specially adapted for cigars, cigarettes, simulated smoking devices or cigarettes therefor specially adapted for simulated smoking devices or cigarettes therefor with means for refilling of liquid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
    • A24F40/48—Fluid transfer means, e.g. pumps
    • A24F40/485—Valves; Apertures
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/90—Arrangements or methods specially adapted for charging batteries thereof
    • A24F40/95—Arrangements or methods specially adapted for charging batteries thereof structurally associated with cases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10—Devices using liquid inhalable precursors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3653—General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/04—Tools for specific apparatus
    • A61M2209/045—Tools for specific apparatus for filling, e.g. for filling reservoirs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

An inhaler comprising a reservoir (2) of an inhalable composition, a heater (6) to selectably volatilise at least some components of the composition, and a power source (8) arranged to selectively supply electrical power to the heater when the user inhales from the inhaler, the inhalable composition comprising: • nicotine or a pharmaceutically acceptable derivative or salt thereof, • a glycol and/or glycol ether, and • a propellant, wherein the propellant is present in an amount of from greater than 0 %w/w to less than 95 %w/w based on the total weight of the composition.
PCT/GB2016/052885 2015-09-18 2016-09-15 An inhalable composition and an inhaler WO2017046593A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP16770320.6A EP3349605A2 (en) 2015-09-18 2016-09-15 An inhalable composition and an inhaler
CN201680066605.8A CN108348013A (en) 2015-09-18 2016-09-15 Inhalable synthetic and inhalator

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1516558.2A GB2542404B (en) 2015-09-18 2015-09-18 An inhalable composition and an inhaler
GB1516558.2 2015-09-18

Publications (2)

Publication Number Publication Date
WO2017046593A2 WO2017046593A2 (en) 2017-03-23
WO2017046593A3 true WO2017046593A3 (en) 2017-04-27

Family

ID=54544456

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2016/052885 WO2017046593A2 (en) 2015-09-18 2016-09-15 An inhalable composition and an inhaler

Country Status (4)

Country Link
EP (1) EP3349605A2 (en)
CN (1) CN108348013A (en)
GB (1) GB2542404B (en)
WO (1) WO2017046593A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD825102S1 (en) 2016-07-28 2018-08-07 Juul Labs, Inc. Vaporizer device with cartridge
USD849996S1 (en) 2016-06-16 2019-05-28 Pax Labs, Inc. Vaporizer cartridge
US10701975B2 (en) 2013-12-23 2020-07-07 Juul Labs, Inc. Vaporization device systems and methods
US10865001B2 (en) 2016-02-11 2020-12-15 Juul Labs, Inc. Fillable vaporizer cartridge and method of filling

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10244793B2 (en) 2005-07-19 2019-04-02 Juul Labs, Inc. Devices for vaporization of a substance
US10279934B2 (en) 2013-03-15 2019-05-07 Juul Labs, Inc. Fillable vaporizer cartridge and method of filling
US10076139B2 (en) 2013-12-23 2018-09-18 Juul Labs, Inc. Vaporizer apparatus
US10159282B2 (en) 2013-12-23 2018-12-25 Juul Labs, Inc. Cartridge for use with a vaporizer device
US20160366947A1 (en) 2013-12-23 2016-12-22 James Monsees Vaporizer apparatus
US10058129B2 (en) 2013-12-23 2018-08-28 Juul Labs, Inc. Vaporization device systems and methods
USD842536S1 (en) 2016-07-28 2019-03-05 Juul Labs, Inc. Vaporizer cartridge
CN112155255A (en) 2014-12-05 2021-01-01 尤尔实验室有限公司 Corrective dose control
CO2018009342A2 (en) 2016-02-11 2018-09-20 Juul Labs Inc Secure fixing cartridges for vaporizing devices
US10405582B2 (en) 2016-03-10 2019-09-10 Pax Labs, Inc. Vaporization device with lip sensing
US10111468B2 (en) * 2016-06-13 2018-10-30 Db Innovation Inc. Vaporization device
USD836541S1 (en) 2016-06-23 2018-12-25 Pax Labs, Inc. Charging device
USD851830S1 (en) 2016-06-23 2019-06-18 Pax Labs, Inc. Combined vaporizer tamp and pick tool
USD887632S1 (en) 2017-09-14 2020-06-16 Pax Labs, Inc. Vaporizer cartridge
GB2604314A (en) * 2017-09-22 2022-09-07 Nerudia Ltd Device, system and method
DE102019109079B4 (en) * 2018-07-03 2020-06-04 MO GmbH & Co. KG Aerosol dispersion device
US11413409B2 (en) 2018-09-12 2022-08-16 Juul Labs, Inc. Vaporizer including positive temperature coefficient of resistivity (PTCR) heating element
EP3861875A1 (en) * 2020-02-05 2021-08-11 JT International SA Pressurized cartomizer
GB2595692A (en) * 2020-06-03 2021-12-08 Senzer Ltd A refill for an inhaler particularly a cannabinoid inhaler
TW202310757A (en) * 2021-08-11 2023-03-16 新加坡商Ｙｓｑ國際私人有限公司 Device for storage and inhalation of nicotine and method for manufacturing the same
IT202100027086A1 (en) * 2021-10-21 2023-04-21 Alberto Patarchi PORTABLE REGULATOR FOR THE TREATMENT OR PREVENTION OF AN INFECTION OR DISEASE CAUSED BY A VIRUS

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1017032A (en) * 1963-12-12 1966-01-12 Aerosmoke Ltd Aerosol compositions
GB1528391A (en) * 1976-01-05 1978-10-11 Gildemeister V Aerosol compositions
WO2009001085A2 (en) * 2007-06-25 2008-12-31 Kind Consumer Limited An inhalable composition comprising nicotine
EP2100525A1 (en) * 2008-03-14 2009-09-16 Philip Morris Products S.A. Electrically heated aerosol generating system and method
EP2319334A1 (en) * 2009-10-27 2011-05-11 Philip Morris Products S.A. A smoking system having a liquid storage portion
WO2013083638A1 (en) * 2011-12-08 2013-06-13 Philip Morris Products S.A. An aerosol generating device with air flow nozzles
WO2014033437A2 (en) * 2012-08-28 2014-03-06 Kind Consumer Limited Nicotine composition
US20150245654A1 (en) * 2014-02-28 2015-09-03 Beyond Twenty Ltd. E-cigarette personal vaporizer

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Publication number Priority date Publication date Assignee Title
CN201054978Y (en) * 2007-03-12 2008-05-07 杨金辉 Simulated cigarette electronic apparatus
WO2015042412A1 (en) * 2013-09-20 2015-03-26 E-Nicotine Technology. Inc. Devices and methods for modifying delivery devices

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1017032A (en) * 1963-12-12 1966-01-12 Aerosmoke Ltd Aerosol compositions
GB1528391A (en) * 1976-01-05 1978-10-11 Gildemeister V Aerosol compositions
WO2009001085A2 (en) * 2007-06-25 2008-12-31 Kind Consumer Limited An inhalable composition comprising nicotine
EP2100525A1 (en) * 2008-03-14 2009-09-16 Philip Morris Products S.A. Electrically heated aerosol generating system and method
EP2319334A1 (en) * 2009-10-27 2011-05-11 Philip Morris Products S.A. A smoking system having a liquid storage portion
WO2013083638A1 (en) * 2011-12-08 2013-06-13 Philip Morris Products S.A. An aerosol generating device with air flow nozzles
WO2014033437A2 (en) * 2012-08-28 2014-03-06 Kind Consumer Limited Nicotine composition
US20150245654A1 (en) * 2014-02-28 2015-09-03 Beyond Twenty Ltd. E-cigarette personal vaporizer

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10701975B2 (en) 2013-12-23 2020-07-07 Juul Labs, Inc. Vaporization device systems and methods
US10865001B2 (en) 2016-02-11 2020-12-15 Juul Labs, Inc. Fillable vaporizer cartridge and method of filling
USD849996S1 (en) 2016-06-16 2019-05-28 Pax Labs, Inc. Vaporizer cartridge
USD825102S1 (en) 2016-07-28 2018-08-07 Juul Labs, Inc. Vaporizer device with cartridge

Also Published As

Publication number Publication date
WO2017046593A2 (en) 2017-03-23
GB201516558D0 (en) 2015-11-04
GB2542404B (en) 2019-08-14
EP3349605A2 (en) 2018-07-25
GB2542404A (en) 2017-03-22
CN108348013A (en) 2018-07-31

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