ES2389285T3 - Péptidos bioactivos cortos y procedimientos para su uso - Google Patents

Péptidos bioactivos cortos y procedimientos para su uso Download PDF

Info

Publication number
ES2389285T3
ES2389285T3 ES09159563T ES09159563T ES2389285T3 ES 2389285 T3 ES2389285 T3 ES 2389285T3 ES 09159563 T ES09159563 T ES 09159563T ES 09159563 T ES09159563 T ES 09159563T ES 2389285 T3 ES2389285 T3 ES 2389285T3
Authority
ES
Spain
Prior art keywords
seq
peptides
peptide
flak
flak50
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES09159563T
Other languages
English (en)
Spanish (es)
Inventor
Don R. Owen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helix Biomedix Inc
Original Assignee
Helix Biomedix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/820,053 external-priority patent/US6875744B2/en
Application filed by Helix Biomedix Inc filed Critical Helix Biomedix Inc
Application granted granted Critical
Publication of ES2389285T3 publication Critical patent/ES2389285T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723Cationic antimicrobial peptides, e.g. defensins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Insects & Arthropods (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ES09159563T 2001-03-28 2002-03-28 Péptidos bioactivos cortos y procedimientos para su uso Expired - Lifetime ES2389285T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US27950501P 2001-03-28 2001-03-28
US279505 2001-03-28
US09/820,053 US6875744B2 (en) 2001-03-28 2001-03-28 Short bioactive peptides
US820053 2001-03-28

Publications (1)

Publication Number Publication Date
ES2389285T3 true ES2389285T3 (es) 2012-10-24

Family

ID=26959709

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09159563T Expired - Lifetime ES2389285T3 (es) 2001-03-28 2002-03-28 Péptidos bioactivos cortos y procedimientos para su uso

Country Status (8)

Country Link
US (1) US7381704B2 (enExample)
EP (2) EP2105141B1 (enExample)
JP (2) JP4310107B2 (enExample)
KR (1) KR100891157B1 (enExample)
AU (1) AU2002255952A1 (enExample)
CA (1) CA2441562C (enExample)
ES (1) ES2389285T3 (enExample)
WO (1) WO2002079408A2 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004091495A2 (en) * 2003-04-09 2004-10-28 University Of Utah Research Foundation Compositions and methods related to production of erythropoietin
JP2005281225A (ja) * 2004-03-30 2005-10-13 Japan Science & Technology Agency 新規塩基性抗菌ペプチド及びその利用
KR20080042843A (ko) * 2005-07-27 2008-05-15 나스텍 파마수티컬 컴퍼니 인코포레이티드 치료제의 점막 전달 향상을 위한 밀착 연접 조절 펩티드성분
US7601361B2 (en) * 2005-10-03 2009-10-13 E. I. Du Pont De Nemours And Company Process for providing antimicrobial surfaces
US8168181B2 (en) 2006-02-13 2012-05-01 Alethia Biotherapeutics, Inc. Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
CA2822302A1 (en) 2006-02-13 2007-08-23 Alethia Biotherapeutics Inc. Methods of impairing osteoclast differentiation
KR101552453B1 (ko) * 2006-06-01 2015-09-11 데라퓨틱 펩타이즈, 인코포레이션 중합성 생계면활성제
RU2441877C2 (ru) 2006-06-13 2012-02-10 Хеликс Байомедикс Инк. Тетрапептид, композиция (варианты) и способ стимуляции продукции коллагена фибробластом
KR100742982B1 (ko) * 2006-06-22 2007-07-26 케이맥(주) 초점 타원계측기
US7696174B2 (en) * 2007-01-05 2010-04-13 Helix Biomedix, Inc. Short bio-active peptides for cellular and immunological modulation
EP2152726B8 (en) * 2007-05-01 2015-02-18 Fundação de Amparo à Pesquisa do Estado de São Paulo - FAPESP Analgesic compounds
CN101855235B (zh) 2007-10-29 2013-04-24 赫里克斯生物医疗公司 保护性皮肤护理四肽
GB0803352D0 (en) * 2008-02-22 2008-04-02 Ntnu Technology Transfer As Oligopeptidic compounds and uses thereof
EP2168591A1 (en) * 2008-09-24 2010-03-31 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Antimicrobial peptides
US20120270770A1 (en) * 2010-08-03 2012-10-25 Jesse Michael Jaynes Anti-angiogenic peptides and their uses
WO2014012165A1 (en) 2012-07-19 2014-01-23 Alethia Biotherapeutics Inc. Anti-siglec-15 antibodies
ITBS20120126A1 (it) * 2012-08-01 2014-02-02 Paoli Ambrosi Gianfranco De Composizione antibatterica per uso topico
JP2016518352A (ja) * 2013-04-09 2016-06-23 モヘイ エルディン エラウダン,カーレド 悪性腫瘍のコントロールにおける単剤治療としての新規ペプチド
GB201319620D0 (en) 2013-11-06 2013-12-18 Norwegian University Of Science And Technology Immunosuppressive agents and their use in therapy
KR102478073B1 (ko) 2014-10-14 2022-12-16 립타이드 바이오사이언스, 인코포레이티드 항-염증 특성을 갖는 펩타이드
CN105061562B (zh) * 2015-09-16 2018-01-12 山东电力中心医院 一种具有抗肺癌作用的寡肽及其应用
US9439917B1 (en) * 2015-12-28 2016-09-13 Shetal Amit Shah Anti-blepharitis compositions and their use
JP7105696B2 (ja) 2016-02-29 2022-07-25 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド 感染症を治療するステープル化細胞内ターゲティング抗微生物ペプチド
JP7305614B2 (ja) 2017-07-19 2023-07-10 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド 抗生物質耐性細菌感染症の処置のための安定化抗菌ペプチド
WO2019210377A1 (en) * 2018-04-30 2019-11-07 L'oreal Bioactive peptides having high binding affinity to human muscular nicotinic acetylcholine receptor
FR3099060B1 (fr) * 2019-07-26 2022-01-14 Bionuclei Complexe hybride mineral et organique et son utilisation pour le maintien de l’equilibre microbiologique de la peau et/ou d’une composition cosmetique et/ou dermopharmaceutique
WO2025122089A1 (en) * 2023-12-06 2025-06-12 Karadeni̇z Tekni̇k Uni̇versi̇tesi̇ Teknoloji̇ Transferi̇ Uygulama Ve Arasti̇rma Merkezi̇ Development of a novel chitosan conjugated antimicrobial peptide as an alternative to antibiotics
WO2025157595A2 (en) * 2024-01-25 2025-07-31 Lipotrue, S.L. Peptides and cosmetic compositions for use in the treatment of acne and its related skin conditions

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4355104A (en) 1980-06-17 1982-10-19 Kabigen Ab Bacteriolytic proteins
US4520016A (en) 1980-06-17 1985-05-28 Kabigen Ab Bacteriolytic proteins
US5861478A (en) 1987-07-06 1999-01-19 Helix Biomedix, Inc. Lytic peptides
CA1327311C (en) * 1987-07-06 1994-03-01 Jesse M. Jaynes Therapeutic antimicrobial polypeptides, their use and methods for preparation
KR970006154B1 (ko) * 1987-07-06 1997-04-24 루이지아나 스테이트 유니버시티 아그리컬춰럴 앤드 메카니칼 컬리지 용해성 펩티드에 의한 진핵 병원체와 신생물의 억제 및 섬유아세포와 임파구의 자극
WO1990012866A1 (en) * 1989-04-10 1990-11-01 Louisiana State University And Agricultural And Mechanical College Lytic peptides, use for growth, infection and cancer
WO1992017195A1 (en) * 1991-04-08 1992-10-15 Magainin Pharmaceuticals, Inc. Novel peptide compositions and uses therefor
US5561107A (en) 1993-06-04 1996-10-01 Demeter Biotechnologies, Ltd. Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides
US5955573A (en) * 1993-06-04 1999-09-21 Demegen, Inc. Ubiquitin-lytic peptide fusion gene constructs, protein products deriving therefrom, and methods of making and using same
AU7050294A (en) * 1993-06-04 1995-01-03 Demeter Biotechnologies, Ltd. Method of treating pulmonary disease states with non-naturally occurring amphipathic peptides
AU1086595A (en) * 1993-11-08 1995-05-29 Demeter Biotechnologies, Ltd. Methylated lysine-rich lytic peptides and method of making same by reductive alkylation
US5789542A (en) * 1994-04-22 1998-08-04 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Amphipathic peptides
IL114697A0 (en) * 1994-07-22 1995-11-27 Demeter Biotech Ltd Polypeptides comprising ubiquitin-lytic peptide fusion protein products deriving therefrom their preparation and use
EP0866805A1 (en) * 1995-12-12 1998-09-30 Karolinska Innovations AB PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b)
US6566334B1 (en) * 1997-02-06 2003-05-20 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Short amphipathic peptides with activity against bacteria and intracellular pathogens
US6635740B1 (en) * 1997-03-27 2003-10-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Ligand/lytic peptide compositions and methods of use
US6958212B1 (en) * 1999-02-01 2005-10-25 Eidgenossische Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
WO2001049834A2 (en) 2000-01-06 2001-07-12 Monsanto Technology Llc Preparation of deallergenized patatin proteins and patatin permutein proteins

Also Published As

Publication number Publication date
JP4484941B2 (ja) 2010-06-16
CA2441562C (en) 2013-05-14
CA2441562A1 (en) 2002-10-10
JP2005506300A (ja) 2005-03-03
WO2002079408A3 (en) 2002-11-28
AU2002255952A1 (en) 2002-10-15
EP1379265A4 (en) 2005-09-14
US20030109452A1 (en) 2003-06-12
HK1135330A1 (en) 2010-06-04
JP2009137992A (ja) 2009-06-25
WO2002079408A2 (en) 2002-10-10
JP4310107B2 (ja) 2009-08-05
KR100891157B1 (ko) 2009-04-07
EP1379265A2 (en) 2004-01-14
KR20040002880A (ko) 2004-01-07
US7381704B2 (en) 2008-06-03
EP2105141A1 (en) 2009-09-30
EP2105141B1 (en) 2012-08-08

Similar Documents

Publication Publication Date Title
ES2389285T3 (es) Péptidos bioactivos cortos y procedimientos para su uso
US6875744B2 (en) Short bioactive peptides
Leippe et al. Cytolytic and antibacterial activity of synthetic peptides derived from amoebapore, the pore-forming peptide of Entamoeba histolytica.
Huttner et al. Antimicrobial peptides as mediators of epithelial host defense
EP1853620B1 (en) Antimicrobial hexapeptides
Lee et al. Styelins, broad-spectrum antimicrobial peptides from the solitary tunicate, Styela clava
KR102499670B1 (ko) 라이신 치환을 포함하는 Romo1 유래 항균 펩타이드 및 그 변이체
KR20180056226A (ko) 전복에서 유래한 항균 펩타이드 유사체 및 이를 포함하는 항균용 약학 조성물
US5792831A (en) Analogues of magainin peptides containing D-amino acids
JPH08500818A (ja) N末端置換を有する生物活性ペプチド
US5686563A (en) Biologically active peptides having n-terminal substitutions
US20050209157A1 (en) Short bioactive peptides and methods for their use
EP1334124B1 (en) Diastereomeric peptides and pharmaceutical compositions comprising them
WO2012033450A1 (en) Novel antimicrobial peptides
WO1991017760A1 (en) Composition of and treatment with biologically active peptides having d-amino acid residues
KR101847051B1 (ko) 병원균에 대한 항생활성을 갖는 펩타이드 및 이를 포함하는 항생 펩타이드 조성물
HK1135330B (en) Short bioactive peptides and methods for their use
AU8300598A (en) Biologically active peptides with reduced toxicity in animals and a method for preparing same
Rangel et al. Peptides with Therapeutic Potential against Acinetobacter
IT202100029738A1 (it) Peptide ad attività antimicotica e antibatterica
Tal et al. terial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47 phox. Proceedings of the National Academy of
Fakheri et al. Small but potent killers