ATE127838T1 - Inhibierung von eukaryotischen pathogenen und neoplasmen mit lytischen peptiden. - Google Patents

Inhibierung von eukaryotischen pathogenen und neoplasmen mit lytischen peptiden.

Info

Publication number
ATE127838T1
ATE127838T1 AT88906595T AT88906595T ATE127838T1 AT E127838 T1 ATE127838 T1 AT E127838T1 AT 88906595 T AT88906595 T AT 88906595T AT 88906595 T AT88906595 T AT 88906595T AT E127838 T1 ATE127838 T1 AT E127838T1
Authority
AT
Austria
Prior art keywords
cells
neoplasms
inhibition
sarcotoxin
eucaryotic
Prior art date
Application number
AT88906595T
Other languages
English (en)
Inventor
Jesse M Jaynes
Frederick M Enright
Kenneth L White
Gale Jeffers
Original Assignee
Univ Louisiana State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Louisiana State filed Critical Univ Louisiana State
Application granted granted Critical
Publication of ATE127838T1 publication Critical patent/ATE127838T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Insects & Arthropods (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT88906595T 1987-07-06 1988-07-06 Inhibierung von eukaryotischen pathogenen und neoplasmen mit lytischen peptiden. ATE127838T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6965387A 1987-07-06 1987-07-06
US10217587A 1987-09-29 1987-09-29

Publications (1)

Publication Number Publication Date
ATE127838T1 true ATE127838T1 (de) 1995-09-15

Family

ID=26750283

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88906595T ATE127838T1 (de) 1987-07-06 1988-07-06 Inhibierung von eukaryotischen pathogenen und neoplasmen mit lytischen peptiden.

Country Status (8)

Country Link
US (2) US5962410A (de)
EP (1) EP0383770B1 (de)
JP (1) JP2962555B2 (de)
KR (1) KR970006154B1 (de)
AT (1) ATE127838T1 (de)
AU (1) AU2132088A (de)
DE (1) DE3854476T2 (de)
WO (1) WO1989000194A1 (de)

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US5850025A (en) * 1991-09-19 1998-12-15 Sibia Neurosciences, Inc. Protection of plants against plant pathogens
US5422108A (en) * 1991-09-19 1995-06-06 Smart Plants International Inc. Protection of plants against plant pathogens
ZA927576B (en) * 1991-10-04 1993-04-16 Univ North Carolina State Pathogen-resistant transgenic plants.
US6008436A (en) * 1993-01-21 1999-12-28 North Carolina State University Nematode-resistant transgenic plants
US5968904A (en) * 1993-06-04 1999-10-19 Demegen, Inc. Modified arginine containing lytic peptides and method of making the same by glyoxylation
US6156568A (en) * 1993-06-30 2000-12-05 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Transformed eukaryotic cells
US5548075A (en) * 1993-08-30 1996-08-20 Utah State University DNA cassette and transgenic organisms carrying lytic peptide-encoding genes
US5856178A (en) * 1993-08-30 1999-01-05 Utah State University DNA cassettes for expression of lytic peptides in mammalian cells and transgenic organisms containing same
JP3908274B2 (ja) * 1995-03-09 2007-04-25 ゲーエスエフ−フォルシュンクスツェントラム・フュア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー 遺伝子治療用の抗菌ペプチドをコードする治療用遺伝子を有するベクター
WO1996040879A1 (en) * 1995-06-07 1996-12-19 Utah State University Dna cassettes for expression of lytic peptides in mammalian cells and transgenic organisms containing same
US6635740B1 (en) * 1997-03-27 2003-10-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Ligand/lytic peptide compositions and methods of use
HU221407B1 (hu) 1997-03-28 2002-09-28 Gyula Magvasi Ektodermális eredetû szövetekben fellépõ tumoros burjánzást gátló hatóanyag és készítmény, valamint eljárás elõállításukra
US8283315B2 (en) 1998-08-28 2012-10-09 Lytix Biopharma As Inhibition of tumour growth
GB0605685D0 (en) * 2006-03-21 2006-05-03 Lytix Biopharma As Inhibition of tumour growth
US6451365B1 (en) 2000-07-14 2002-09-17 Rhodia Inc. Antibacterial composition for control of gram positive bacteria in food applications
EP1210456A1 (de) * 1999-07-30 2002-06-05 The Texas A & M University System Antibiotika die auf bakteriophagenlysisproteinen basieren
US20050209157A1 (en) * 2001-03-28 2005-09-22 Owen Donald R Short bioactive peptides and methods for their use
US6875744B2 (en) * 2001-03-28 2005-04-05 Helix Biomedix, Inc. Short bioactive peptides
WO2002079408A2 (en) * 2001-03-28 2002-10-10 Helix Biomedix, Inc. Short bioactive peptides and methods for their use
DE60329382D1 (de) * 2002-04-22 2009-11-05 Dow Global Technologies Inc Kostengünstige herstellung von peptiden
US20040235011A1 (en) * 2002-06-26 2004-11-25 Cooper Richard K. Production of multimeric proteins
US20040172667A1 (en) 2002-06-26 2004-09-02 Cooper Richard K. Administration of transposon-based vectors to reproductive organs
US7527966B2 (en) * 2002-06-26 2009-05-05 Transgenrx, Inc. Gene regulation in transgenic animals using a transposon-based vector
JP2006502121A (ja) * 2002-07-23 2006-01-19 テバ ジョジセルジャール レースベニュタールシャシャーグ １Ｈ−イミダゾ［４，５−ｃ］キノリン−４−フタルイミド中間体を介する１Ｈ−イミダゾ−［４，５−ｃ］キノリン−４−アミンの調製
US8071364B2 (en) 2003-12-24 2011-12-06 Transgenrx, Inc. Gene therapy using transposon-based vectors
WO2005090385A2 (en) * 2004-03-18 2005-09-29 Ansata Therapeutics, Inc. Compositions having antimicrobial activity and uses thereof
US7354888B2 (en) 2004-11-10 2008-04-08 Danisco A/S Antibacterial composition and methods thereof comprising a ternary builder mixture
JP5335241B2 (ja) * 2005-02-09 2013-11-06 ヘリックス バイオメディックス インコーポレイテッド 抗微生物ヘキサペプチド
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WO2009094634A1 (en) * 2008-01-24 2009-07-30 Esperance Pharmaceuticals Lytic domain fusion constructs and methods of making and using same
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EP2446028B1 (de) 2009-06-26 2018-04-04 Lysando Aktiengesellschaft Antimikrobielle wirkstoffe
PL2445515T3 (pl) 2009-06-26 2016-10-31 Środki przeciwdrobnoustrojowe
EP2468856A1 (de) * 2010-12-23 2012-06-27 Lysando Aktiengesellschaft Antimikrobielle Mittel
US9492563B2 (en) 2012-10-30 2016-11-15 Esperance Pharmaceuticals, Inc. Antibody/drug conjugates and methods of use
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WO2016210442A1 (en) * 2015-06-26 2016-12-29 The Board Of Trustees Of The University Of Illinois Antimicrobial alpha-helical cationic polypeptides
US11225507B2 (en) 2017-01-25 2022-01-18 The Board Of Trustees Of The University Of Illinois Conformation switchable antimicrobial peptides and methods of using the same
US10413584B1 (en) 2018-08-29 2019-09-17 Riptide Bioscience, Inc. Peptides having immunomodulatory properties
US10548944B1 (en) 2018-10-19 2020-02-04 Riptide Bioscience, Inc. Antimicrobial peptides and methods of using the same
CA3134420A1 (en) 2019-04-12 2020-10-15 Riptide Bioscience, Inc. Methods for modulating macrophage activity

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Also Published As

Publication number Publication date
AU2132088A (en) 1989-01-30
KR970006154B1 (ko) 1997-04-24
EP0383770A1 (de) 1990-08-29
EP0383770B1 (de) 1995-09-13
US5962410A (en) 1999-10-05
JP2962555B2 (ja) 1999-10-12
JPH03503522A (ja) 1991-08-08
DE3854476T2 (de) 1996-04-04
DE3854476D1 (de) 1995-10-19
WO1989000194A1 (en) 1989-01-12
KR890701722A (ko) 1989-12-21
US6440935B1 (en) 2002-08-27
EP0383770A4 (en) 1991-08-14

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