ATE452190T1 - Verfahren zur isolierung und reinigung von g-csf - Google Patents

Verfahren zur isolierung und reinigung von g-csf

Info

Publication number
ATE452190T1
ATE452190T1 AT95119327T AT95119327T ATE452190T1 AT E452190 T1 ATE452190 T1 AT E452190T1 AT 95119327 T AT95119327 T AT 95119327T AT 95119327 T AT95119327 T AT 95119327T AT E452190 T1 ATE452190 T1 AT E452190T1
Authority
AT
Austria
Prior art keywords
csf
genetically engineered
isolation
purification
animals
Prior art date
Application number
AT95119327T
Other languages
English (en)
Inventor
Thomas C Boone
Allan L Miller
Jeffrey W Andresen
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE452190T1 publication Critical patent/ATE452190T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/202—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT95119327T 1988-05-13 1989-05-12 Verfahren zur isolierung und reinigung von g-csf ATE452190T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19385788A 1988-05-13 1988-05-13
US34801189A 1989-05-09 1989-05-09

Publications (1)

Publication Number Publication Date
ATE452190T1 true ATE452190T1 (de) 2010-01-15

Family

ID=26889429

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95119327T ATE452190T1 (de) 1988-05-13 1989-05-12 Verfahren zur isolierung und reinigung von g-csf

Country Status (12)

Country Link
US (1) US5849883A (de)
EP (2) EP0347041A3 (de)
JP (1) JP2796388B2 (de)
KR (1) KR0133561B1 (de)
AT (1) ATE452190T1 (de)
AU (3) AU636127B2 (de)
DE (1) DE68929566D1 (de)
DK (1) DK175245B1 (de)
FI (1) FI900178A0 (de)
NO (1) NO300217B1 (de)
NZ (1) NZ229098A (de)
WO (1) WO1989010932A1 (de)

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US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
US6048837A (en) * 1994-08-17 2000-04-11 The Rockefeller University OB polypeptides as modulators of body weight
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US6471956B1 (en) 1994-08-17 2002-10-29 The Rockefeller University Ob polypeptides, modified forms and compositions thereto
US6124448A (en) * 1994-08-17 2000-09-26 The Rockfeller University Nucleic acid primers and probes for the mammalian OB gene
US6350730B1 (en) 1994-08-17 2002-02-26 The Rockefeller University OB polypeptides and modified forms as modulators of body weight
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US7220407B2 (en) 2003-10-27 2007-05-22 Amgen Inc. G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
EP2335716A3 (de) 2004-02-11 2011-10-19 Amylin Pharmaceuticals Inc. Pankreas-polypeptidfamilienmotive und diese enthaltende polypeptide
EP2417980A1 (de) 2004-02-11 2012-02-15 Amylin Pharmaceuticals Inc. Hybridpolypeptide mit auswahlbaren Eigenschaften
NZ571824A (en) 2004-02-11 2010-04-30 Amylin Pharmaceuticals Inc Amylin family peptides and methods for making and using them
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BRPI0611221A2 (pt) 2005-06-01 2010-08-24 Maxygen Holdings Ltd polipeptÍdeos de g-csf peguilados e mÉtodos de produÇço dos mesmos
DE102005033250A1 (de) 2005-07-15 2007-01-18 Bioceuticals Arzneimittel Ag Verfahren zur Reinigung von G-CSF
KR100735784B1 (ko) * 2005-07-20 2007-07-06 재단법인 목암생명공학연구소 인간 과립구콜로니자극인자 변이체 및 이의 화학적 접합물
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DE102006009437A1 (de) 2006-03-01 2007-09-13 Bioceuticals Arzneimittel Ag G-CSF-Flüssigformulierung
US9176145B2 (en) 2006-07-21 2015-11-03 Femalon S.P.R.L. Kit for predicting implantation success in assisted fertilization
WO2008116470A1 (en) * 2007-03-26 2008-10-02 Drugrecure Aps Enhancing pulmonary host defence via administration of granulocyte- colony stimulating factor
MX2010002448A (es) 2007-08-27 2010-10-04 Biogenerix Ag Formulacion liquida del g-csf conjugado.
EP2281827B1 (de) 2008-05-08 2013-08-21 Ajinomoto Co., Inc. Verfahren zur rückfaltung einer proteinstruktur
UA118536C2 (uk) * 2008-07-23 2019-02-11 Амбркс, Інк. Модифікований поліпептид бичачого гранулоцитарного колонієстимулювального фактора та його застосування
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EP2477643A1 (de) 2009-09-18 2012-07-25 Novo Nordisk A/S V2-rezeptoragonisten mit langzeitwirkung
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JP2013515081A (ja) 2009-12-21 2013-05-02 アンブルックス，インコーポレイテッド 修飾されているブタのソマトトロピンポリペプチドおよびそれらの使用
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RU2487885C2 (ru) * 2010-07-20 2013-07-20 Зао "Биокад" Способ крупномасштабного получения, выделения и очистки рекомбинантного гранулоцитарного колониестимулирующего фактора человека
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US8653058B2 (en) 2011-04-05 2014-02-18 Kythera Biopharmaceuticals, Inc. Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits
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Also Published As

Publication number Publication date
EP0719860A1 (de) 1996-07-03
NO900185D0 (no) 1990-01-12
AU4197393A (en) 1993-10-28
AU4197293A (en) 1993-10-28
NZ229098A (en) 1992-10-28
US5849883A (en) 1998-12-15
EP0347041A3 (de) 1990-11-22
NO900185L (no) 1990-03-12
JPH02504521A (ja) 1990-12-20
WO1989010932A1 (en) 1989-11-16
DK9290D0 (da) 1990-01-12
DK175245B1 (da) 2004-07-19
AU636127B2 (en) 1993-04-22
FI900178A0 (fi) 1990-01-12
EP0347041A2 (de) 1989-12-20
KR900701824A (ko) 1990-12-04
JP2796388B2 (ja) 1998-09-10
NO300217B1 (no) 1997-04-28
DE68929566D1 (de) 2010-01-28
KR0133561B1 (ko) 1998-04-21
AU4781290A (en) 1990-11-15
AU661172B2 (en) 1995-07-13
EP0719860B1 (de) 2009-12-16
DK9290A (da) 1990-03-09

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