PT88590A - Process for preparing an inactivated vaccine composition - Google Patents

Process for preparing an inactivated vaccine composition

Info

Publication number
PT88590A
PT88590A PT88590A PT8859088A PT88590A PT 88590 A PT88590 A PT 88590A PT 88590 A PT88590 A PT 88590A PT 8859088 A PT8859088 A PT 8859088A PT 88590 A PT88590 A PT 88590A
Authority
PT
Portugal
Prior art keywords
preparing
vaccine composition
inactivated vaccine
compositions
inactivating
Prior art date
Application number
PT88590A
Other languages
English (en)
Other versions
PT88590B (pt
Inventor
Dale Bordt
Hans Draayer
Original Assignee
Beecham Inc
Beecham Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Inc, Beecham Lab filed Critical Beecham Inc
Publication of PT88590A publication Critical patent/PT88590A/pt
Publication of PT88590B publication Critical patent/PT88590B/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/155Paramyxoviridae, e.g. parainfluenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/215Coronaviridae, e.g. avian infectious bronchitis virus
    • A61K39/225Porcine transmissible gastroenteritis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • A61K39/265Infectious rhinotracheitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/20011Coronaviridae
    • C12N2770/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/20011Coronaviridae
    • C12N2770/20061Methods of inactivation or attenuation
    • C12N2770/20063Methods of inactivation or attenuation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
PT88590A 1987-09-28 1988-09-26 Processo para a preparacao de uma composicao vacina inactivada PT88590B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10182287A 1987-09-28 1987-09-28

Publications (2)

Publication Number Publication Date
PT88590A true PT88590A (pt) 1988-10-01
PT88590B PT88590B (pt) 1993-04-30

Family

ID=22286587

Family Applications (2)

Application Number Title Priority Date Filing Date
PT88590A PT88590B (pt) 1987-09-28 1988-09-26 Processo para a preparacao de uma composicao vacina inactivada
PT88591A PT88591B (pt) 1987-09-28 1988-09-26 Processo para a preparacao de uma composicao farmaceutica substancialmente livre de virus ou bacterias

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT88591A PT88591B (pt) 1987-09-28 1988-09-26 Processo para a preparacao de uma composicao farmaceutica substancialmente livre de virus ou bacterias

Country Status (14)

Country Link
EP (2) EP0310317B1 (pt)
JP (2) JP2733844B2 (pt)
KR (2) KR0135426B1 (pt)
AT (2) ATE117899T1 (pt)
AU (2) AU624081B2 (pt)
CA (2) CA1331562C (pt)
DE (2) DE3886332T2 (pt)
DK (2) DK175379B1 (pt)
ES (2) ES2067474T3 (pt)
GR (1) GR3015608T3 (pt)
IE (2) IE60950B1 (pt)
NZ (2) NZ226332A (pt)
PT (2) PT88590B (pt)
ZA (2) ZA887196B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE60950B1 (en) * 1987-09-28 1994-09-07 Beecham Inc Inactivation of viruses and bacteria
JPH05502443A (ja) * 1989-09-25 1993-04-28 ジェネティックス・インスティテュート・インコーポレイテッド 幹細胞の成長阻害法
US5276142A (en) * 1989-12-11 1994-01-04 American Cyanamid Company Process for purification of a 69000 dalton antigenic protein from Bordetella pertussis
EP0460480B1 (en) * 1990-06-07 1996-01-24 Bayer Corporation Bacterin for the treatment of necrophorum diseases and a method for the production thereof
US6372224B1 (en) 1990-11-14 2002-04-16 Pfizer Inc. Canine coronavirus S gene and uses therefor
US6057436A (en) * 1990-11-14 2000-05-02 Pfizer Inc. Canine coronavirus S gene and uses therefor
JPH0813753B2 (ja) * 1992-05-22 1996-02-14 株式会社微生物化学研究所 牛伝染性鼻気管炎ウイルス感染症、牛ウイルス性下痢−粘膜病ウイルス感染症、パラインフルエンザ3型ウイルス感染症、牛rsウイルス感染症および牛アデノ7型ウイルス感染症5種混合生ワクチン
CA2146321A1 (en) * 1992-10-05 1994-04-14 Cassius M. Tucker High potency vaccines
JP2521226B2 (ja) * 1993-01-28 1996-08-07 株式会社微生物化学研究所 犬用多種混合ワクチン
EP0612532A3 (en) * 1993-02-26 1998-02-04 Solvay Animal Health, Inc. Canine coronavirus vaccine from feline enteric coronavirus
US5750112A (en) * 1993-02-26 1998-05-12 Solvay Animal Health, Inc. Canine coronavirus vaccine from feline enteric coronavirus
US5362442A (en) 1993-07-22 1994-11-08 2920913 Canada Inc. Method for sterilizing products with gamma radiation
KR100402379B1 (ko) * 1993-08-06 2004-03-24 코노트 래보러토리즈 리미티드 불활성화된호흡기신시튬바이러스백신
US6682746B2 (en) 1995-09-21 2004-01-27 Kristina J. Hennessy Adjuvanted vaccine which is substantially free of non-host albumin
CA2184132C (en) 1995-09-21 2011-03-15 Kristina J. Hennessy An adjuvanted vaccine which is substantially free of non-host albumin
US5853715A (en) * 1996-08-16 1998-12-29 Bayer Corporation Cross-protective equine herpesvirus preparations and method of making and using the same
UA78180C2 (uk) * 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
EP0978286A1 (en) * 1998-08-07 2000-02-09 Bayer Corporation Cross-protective equine herpesvirus preparations and method of making and using the same
US6682695B2 (en) 2001-03-23 2004-01-27 Clearant, Inc. Methods for sterilizing biological materials by multiple rates
US6696060B2 (en) 2001-06-14 2004-02-24 Clearant, Inc. Methods for sterilizing preparations of monoclonal immunoglobulins
US6946098B2 (en) 2001-08-10 2005-09-20 Clearant, Inc. Methods for sterilizing biological materials
US7252799B2 (en) 2001-08-31 2007-08-07 Clearant, Inc. Methods for sterilizing preparations containing albumin
US6749851B2 (en) 2001-08-31 2004-06-15 Clearant, Inc. Methods for sterilizing preparations of digestive enzymes
US6783968B2 (en) 2001-09-24 2004-08-31 Clearant, Inc. Methods for sterilizing preparations of glycosidases
US20030095890A1 (en) 2001-09-24 2003-05-22 Shirley Miekka Methods for sterilizing biological materials containing non-aqueous solvents
US6908591B2 (en) 2002-07-18 2005-06-21 Clearant, Inc. Methods for sterilizing biological materials by irradiation over a temperature gradient
US7682619B2 (en) 2006-04-06 2010-03-23 Cornell Research Foundation, Inc. Canine influenza virus
CN103709248B (zh) * 2013-12-24 2019-07-16 北京大北农科技集团股份有限公司动物医学研究中心 一种抗猪传染性胃肠炎病毒高免血清及其制备方法
DE202020001666U1 (de) 2020-04-21 2020-06-08 Walther Enßlin Imprägnierung der Oberfläche von Kleidung, Schutzkleidung, Gewebehandschuhen gegen Viren aus den Tröpfchen der Atemluft
DE202020003865U1 (de) 2020-09-11 2021-09-22 Karin Emde Einfangen und Vernichten von Viren und andere Mikroorganismen in Raumluft und Raumluftfiltern
DE102021001635A1 (de) 2021-03-27 2022-09-29 Karin Emde Abfangen und Vernichten von Viren und andere Mikroorganismen auf Oberflächen, in Raumluft, in der Abluft von Staubsaugern und in Raumluftfiltern.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145144A (en) * 1951-08-09 1964-08-18 Takeda Pharmacentical Ind Ltd Process for manufacturing chromium treated vaccines
FR1488212A (fr) * 1964-06-22 1967-07-13 Behringwerke Ag Procédé permettant d'atténuer le virus de la fièvre aphteuse
DE1253412B (de) * 1964-09-22 1967-11-02 Diamond Lab Inc Verfahren zur Gewinnung eines Impfstoffes gegen infektioese Schweinegastroenteritis
US3925544A (en) * 1971-07-12 1975-12-09 Univ Southern Illinois Bovine vaccines and methods of making and using same
US3907986A (en) * 1972-12-18 1975-09-23 Rit Rech Ind Therapeut Live attenuated infectious bovine rhinotracheitis virus vaccines and preparation thereof
JPS5531762B2 (pt) * 1973-03-28 1980-08-20
DE2860895D1 (en) * 1977-07-22 1981-11-05 Merck & Co Inc Parainfluenza virus vaccine and its preparation
JPS55104215A (en) * 1979-02-06 1980-08-09 Merck & Co Inc Parainfluenza virus vaccine and its manufacture
GB8502399D0 (en) * 1985-01-31 1985-03-06 Akzo Nv Canine parvovirus vaccines
IE60950B1 (en) * 1987-09-28 1994-09-07 Beecham Inc Inactivation of viruses and bacteria

Also Published As

Publication number Publication date
JP2733844B2 (ja) 1998-03-30
EP0310316A3 (en) 1990-02-14
ES2067474T3 (es) 1995-04-01
GR3015608T3 (en) 1995-06-30
NZ226332A (en) 1991-10-25
DE3886332D1 (de) 1994-01-27
PT88591B (pt) 1992-11-30
DK534188D0 (da) 1988-09-26
AU2281488A (en) 1989-04-06
ATE117899T1 (de) 1995-02-15
DK534288A (da) 1989-03-29
AU624339B2 (en) 1992-06-11
JPH01230532A (ja) 1989-09-14
EP0310316B1 (en) 1995-02-01
IE60950B1 (en) 1994-09-07
IE882909L (en) 1989-03-28
AU624081B2 (en) 1992-06-04
NZ226333A (en) 1991-09-25
DK175308B1 (da) 2004-08-16
CA1332919C (en) 1994-11-08
CA1331562C (en) 1994-08-23
DK534288D0 (da) 1988-09-26
IE66015B1 (en) 1995-11-29
ZA887195B (en) 1989-07-26
EP0310317A3 (en) 1990-02-14
KR0135426B1 (ko) 1998-04-23
EP0310316A2 (en) 1989-04-05
DK534188A (da) 1989-03-29
DK175379B1 (da) 2004-09-20
PT88590B (pt) 1993-04-30
ES2061673T3 (es) 1994-12-16
IE882908L (en) 1989-03-28
KR890004725A (ko) 1989-05-09
ATE98680T1 (de) 1994-01-15
AU2284388A (en) 1989-04-06
ZA887196B (en) 1989-07-26
DE3886332T2 (de) 1994-03-31
EP0310317B1 (en) 1993-12-15
JP2715114B2 (ja) 1998-02-18
JPH01230523A (ja) 1989-09-14
PT88591A (pt) 1988-10-01
EP0310317A2 (en) 1989-04-05
KR890004728A (ko) 1989-05-09
DE3852918T2 (de) 1995-07-13
DE3852918D1 (de) 1995-03-16

Similar Documents

Publication Publication Date Title
PT88590A (pt) Process for preparing an inactivated vaccine composition
NO900185D0 (no) Preparater og fremgangsmaate for behandling eller forhindring av infeksjoner hos dyr.
ATE366312T1 (de) Impfstoff und antitoxine zur behandlung und vorbeugung von c. difficile krankheiten
DE3361598D1 (en) Process for the preparation of polysaccharide-protein complexes from bacterial envelopes, products obtained and immunogenic compostions containing them
ES379641A1 (es) Procedimiento de produccion de antigenos inactivos para preparados farmaceuticos.
IL88971A (en) Disubstituted pyridines, process and intermediates, their preparation and pharmaceutical compositions containing them
PT600396E (pt) Vacinas contra protozoarios intestinais
DE3750886D1 (de) Verwendung eines immunglobulinhaltigen Präparates zur Prophylaxe und Therapie von AIDS beim Menschen.
DE69010523D1 (de) Kit oder Zusammensetzung zur Vorbeugung oder Behandlung von HIV-1 Infektionen.
HUP9700975A2 (hu) Élő, legyengített, Pasteurellaceae családba tartozó, RTX-termelő baktériumok
KR880008812A (ko) 항균성 동결건조 제제
MX169374B (es) Procedimiento para la preparacion de una composicion farmaceutica libre de virus o bacterias vivas

Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19921027

PC3A Transfer or assignment

Free format text: 970331 SMITHKLINE BEECHAM CORPORATION US

PD3A Change of proprietorship