ES2380923T3 - Procedimientos de cuantificación de microARN y ARN interferentes pequeños - Google Patents
Procedimientos de cuantificación de microARN y ARN interferentes pequeños Download PDFInfo
- Publication number
- ES2380923T3 ES2380923T3 ES05715157T ES05715157T ES2380923T3 ES 2380923 T3 ES2380923 T3 ES 2380923T3 ES 05715157 T ES05715157 T ES 05715157T ES 05715157 T ES05715157 T ES 05715157T ES 2380923 T3 ES2380923 T3 ES 2380923T3
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- sequence
- rna
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- lna
- microrna
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
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- General Health & Medical Sciences (AREA)
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| DKPA200400578 | 2004-04-07 | ||
| DK200401146 | 2004-07-23 | ||
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| DKPA200401218 | 2004-08-11 | ||
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| DKPA200401587 | 2004-10-15 | ||
| DKPA200500140 | 2005-01-28 | ||
| DK200500140 | 2005-01-28 | ||
| PCT/DK2005/000239 WO2005098029A2 (en) | 2004-04-07 | 2005-04-07 | Methods for quantification of micrornas and small interfering rnas |
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| ES (1) | ES2380923T3 (https=) |
| WO (1) | WO2005098029A2 (https=) |
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| US8192937B2 (en) | 2004-04-07 | 2012-06-05 | Exiqon A/S | Methods for quantification of microRNAs and small interfering RNAs |
| EP1838870A2 (en) * | 2004-12-29 | 2007-10-03 | Exiqon A/S | NOVEL OLIGONUCLEOTIDE COMPOSITIONS AND PROBE SEQUENCES USEFUL FOR DETECTION AND ANALYSIS OF MICRORNAS AND THEIR TARGET MRNAs |
| JP2008528003A (ja) * | 2005-01-25 | 2008-07-31 | ロゼッタ インファーマティックス エルエルシー | 小ｒｎａ分子の定量方法 |
| US8071306B2 (en) | 2005-01-25 | 2011-12-06 | Merck Sharp & Dohme Corp. | Methods for quantitating small RNA molecules |
| US7556943B2 (en) * | 2005-05-31 | 2009-07-07 | Applied Biosystems, Llc | Linear amplification of short nucleic acids |
| JP2007082436A (ja) * | 2005-09-20 | 2007-04-05 | Bioinformatics Institute For Global Good Inc | 機能性ＲＮＡが制御するターゲットｍＲＮＡの予測・同定方法及びその利用方法 |
| WO2007073737A1 (en) * | 2005-12-29 | 2007-07-05 | Exiqon A/S | Detection of tissue origin of cancer |
| SG10201406016SA (en) | 2006-04-03 | 2014-11-27 | Stella Aps | Pharmaceutical composition comprising anti-mirna antisense oligonucleotides |
| US7955848B2 (en) | 2006-04-03 | 2011-06-07 | Trustees Of Dartmouth College | MicroRNA biomarkers for human breast and lung cancer |
| EP2007888A2 (en) | 2006-04-03 | 2008-12-31 | Santaris Pharma A/S | Pharmaceutical composition comprising anti-mirna antisense oligonucleotides |
| US8207325B2 (en) | 2006-04-03 | 2012-06-26 | Univ. of Copenhagen | MicroRNA biomarkers for human breast and lung cancer |
| US8580494B2 (en) | 2006-08-25 | 2013-11-12 | Research Foundation For Mental Hygiene, Inc. | Methods and compositions for amplification and detection of MicroRNAs |
| WO2008040355A2 (en) * | 2006-10-06 | 2008-04-10 | Exiqon A/S | Novel methods for quantification of micrornas and small interfering rnas |
| US8188255B2 (en) | 2006-10-20 | 2012-05-29 | Exiqon A/S | Human microRNAs associated with cancer |
| EP2090665A2 (en) | 2006-10-20 | 2009-08-19 | Exiqon A/S | Novel human microRNAs associated with cancer |
| EP1914317A1 (en) * | 2006-10-21 | 2008-04-23 | Biolytix AG | A method for qualitative and quantitative detection of short nucleic acid sequences of about 8 to 50 nucleotides in length |
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| KR20100099158A (ko) | 2007-11-09 | 2010-09-10 | 보드 오브 리전츠 더 유니버시티 오브 텍사스 시스템 | 심근세포 생존과 심장 회복을 제어하는 ＭＩＲ-15 집단의 마이크로ＲＮＡｓ |
| WO2009098988A1 (ja) | 2008-02-04 | 2009-08-13 | Genecare Research Institute Co., Ltd. | siRNA検出方法 |
| CA2717792A1 (en) | 2008-03-07 | 2009-09-11 | Santaris Pharma A/S | Pharmaceutical compositions for treatment of microrna related diseases |
| WO2010012667A1 (en) | 2008-08-01 | 2010-02-04 | Santaris Pharma A/S | Micro-rna mediated modulation of colony stimulating factors |
| US20100240049A1 (en) | 2009-01-16 | 2010-09-23 | Cepheid | Methods of Detecting Cervical Cancer |
| CA2787218A1 (en) * | 2009-01-19 | 2010-07-22 | Sistemic Scotland Limited | Methods employing non-coding rna expression assays |
| DK2391736T3 (en) * | 2009-02-02 | 2015-05-11 | Exiqon As | A method for the quantitation of small RNA species |
| US9493832B2 (en) | 2009-02-02 | 2016-11-15 | Cepheid | Methods of detecting sepsis |
| EP2419537B1 (en) | 2009-04-13 | 2014-01-29 | Somagenics, Inc. | Methods and compositions for detection of small rnas |
| ES2599979T3 (es) | 2009-04-24 | 2017-02-06 | Roche Innovation Center Copenhagen A/S | Composiciones farmacéuticas para el tratamiento de pacientes de VHC que no responden al interferón |
| EP2456870A1 (en) | 2009-07-21 | 2012-05-30 | Santaris Pharma A/S | Antisense oligomers targeting pcsk9 |
| KR101822609B1 (ko) * | 2010-06-24 | 2018-01-26 | 주식회사 파나진 | Ｐｎａ 기반의 실시간 ｐｃｒ 클램핑을 이용한 마이크로ｒｎａ 발현양상의 분석 방법 및 키트 |
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| CN102154505B (zh) * | 2011-04-20 | 2013-03-20 | 苟德明 | 一种检测miRNA的方法及引物及其应用 |
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| CN104673901B (zh) * | 2015-02-06 | 2018-05-11 | 中国医学科学院基础医学研究所 | 用于检测靶核酸的用途和试剂盒 |
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| WO2020239822A1 (en) * | 2019-05-27 | 2020-12-03 | The European Molecular Biology Laboratory | Nucleic acid construct binding to influenza polymerase pb1 rna synthesis active site |
| EP3901286A1 (en) * | 2020-04-24 | 2021-10-27 | Mirnax Biosens, S.L. | Bivalent reverse primer |
| ES3030914T3 (en) * | 2019-11-04 | 2025-07-02 | Mirnax Biosens S L | Bivalent reverse primer |
| CN111665351B (zh) * | 2020-06-20 | 2021-12-03 | 江南大学 | 一种快速、特异性测定rna含量的方法 |
| CN113322523B (zh) * | 2021-06-17 | 2024-03-19 | 翌圣生物科技(上海)股份有限公司 | Rna快速建库方法及其应用 |
| CN116200492B (zh) * | 2022-11-08 | 2025-04-01 | 浙江大学 | 一种基于探针锚定双链的小核酸检测试剂盒及其应用 |
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| AU6695600A (en) * | 1999-07-19 | 2001-02-05 | Cambridge University Technical Services Limited | A method for amplifying low abundance nucleic acid sequences and means for performing said method |
| WO2002057479A2 (en) * | 2000-12-27 | 2002-07-25 | Invitrogen Corporation | Primers and methods for the detection and discrimination of nucleic acids |
| US20040235005A1 (en) * | 2002-10-23 | 2004-11-25 | Ernest Friedlander | Methods and composition for detecting targets |
| US7217807B2 (en) * | 2002-11-26 | 2007-05-15 | Rosetta Genomics Ltd | Bioinformatically detectable group of novel HIV regulatory genes and uses thereof |
| JP4230457B2 (ja) * | 2002-12-18 | 2009-02-25 | サード・ウェーブ・テクノロジーズ・インク | 低分子核酸の検出方法 |
| EP1644533A4 (en) * | 2003-07-02 | 2007-11-14 | Perkinelmer Las Inc | ANALYSIS AND METHOD OF MARKING AND DETECTING RNA MICROSEQUENCES AND SMALL INTERFERENCE RNA SEQUENCES |
| JP2007512805A (ja) * | 2003-10-14 | 2007-05-24 | ノバルティス アクチエンゲゼルシャフト | オリゴヌクレオチドマイクロアレイ |
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- 2005-04-07 JP JP2007506659A patent/JP5192229B2/ja not_active Expired - Lifetime
- 2005-04-07 CN CN2005800176883A patent/CN1961081B/zh not_active Expired - Lifetime
- 2005-04-07 DK DK05715157.3T patent/DK1735459T3/da active
- 2005-04-07 AT AT05715157T patent/ATE542918T1/de active
- 2005-04-07 EP EP05715157A patent/EP1735459B1/en not_active Expired - Lifetime
- 2005-04-07 ES ES05715157T patent/ES2380923T3/es not_active Expired - Lifetime
- 2005-04-07 WO PCT/DK2005/000239 patent/WO2005098029A2/en not_active Ceased
Also Published As
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| CN1961081B (zh) | 2012-09-05 |
| JP5192229B2 (ja) | 2013-05-08 |
| WO2005098029A3 (en) | 2005-12-15 |
| EP1735459A2 (en) | 2006-12-27 |
| CA2562390A1 (en) | 2005-10-20 |
| JP2007532100A (ja) | 2007-11-15 |
| DK1735459T3 (da) | 2012-05-29 |
| CN1961081A (zh) | 2007-05-09 |
| CA2562390C (en) | 2014-12-02 |
| EP1735459B1 (en) | 2012-01-25 |
| WO2005098029A2 (en) | 2005-10-20 |
| ATE542918T1 (de) | 2012-02-15 |
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