ES2340662T3 - Factor de crecimiento de fibroblastos (fgf23) nuevo procedimiento para el uso. - Google Patents
Factor de crecimiento de fibroblastos (fgf23) nuevo procedimiento para el uso. Download PDFInfo
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- ES2340662T3 ES2340662T3 ES01952590T ES01952590T ES2340662T3 ES 2340662 T3 ES2340662 T3 ES 2340662T3 ES 01952590 T ES01952590 T ES 01952590T ES 01952590 T ES01952590 T ES 01952590T ES 2340662 T3 ES2340662 T3 ES 2340662T3
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| US6838264B2 (en) | 2000-12-05 | 2005-01-04 | Immutopics, Inc. | Antibodies and peptide antigens for producing antibodies having a selective binding specificity to bioactive intact parathyroid hormone (PTH) 1-84 |
| US7226749B2 (en) | 2000-12-05 | 2007-06-05 | Zahradnik Richard J | Antibodies and peptide antigens for producing antibodies having a selective binding specificity to bioactive intact parathyroid hormone (PTH) 1-84 |
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| CN100519584C (zh) * | 2001-12-28 | 2009-07-29 | 麒麟医药株式会社 | 抗成纤维细胞生长因子23的抗体 |
| US7094551B2 (en) | 2002-09-17 | 2006-08-22 | Zahradnik Richard J | Immunoassays, assay methods, antibodies and method of creating antibodies for detecting FGF-23 |
| JP5118851B2 (ja) * | 2003-11-07 | 2013-01-16 | ノバルティス アーゲー | 線維芽細胞増殖因子フラグメントの使用 |
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| US8012694B2 (en) | 2006-09-14 | 2011-09-06 | Immutopics, Inc. | Assay for the detection of phosphorylated PTH |
| EP2468888B1 (en) * | 2007-01-22 | 2018-04-11 | Medizinische Universität Innsbruck | Novel markers for chronic kidney disease |
| US7883705B2 (en) * | 2007-02-14 | 2011-02-08 | Kyowa Hakko Kirin Co., Ltd. | Anti FGF23 antibody and a pharmaceutical composition comprising the same |
| WO2009091556A2 (en) * | 2008-01-17 | 2009-07-23 | The General Hospital Corporation | Diagnostic methods and kits using fibroblast growth factor-23 |
| TW200936156A (en) | 2008-01-28 | 2009-09-01 | Novartis Ag | Methods and compositions using Klotho-FGF fusion polypeptides |
| US8420088B2 (en) * | 2008-01-28 | 2013-04-16 | Novartis Ag | Methods and compositions using FGF23 fusion polypeptides |
| CN103353532B (zh) * | 2008-04-29 | 2016-05-11 | 诺瓦提斯公司 | 监测成纤维细胞生长因子受体的激酶活性的调节的方法及所述方法的应用 |
| US8889621B2 (en) * | 2009-10-30 | 2014-11-18 | New York University | Inhibiting binding of FGF23 to the binary FGFR-Klotho complex for the treatment of hypophosphatemia |
| US20110195077A1 (en) * | 2010-01-29 | 2011-08-11 | Novartis Ag | Methods and compositions using fgf23 fusion ppolypeptides |
| WO2012029837A1 (ja) | 2010-08-31 | 2012-03-08 | 協和メデックス株式会社 | 線維芽細胞増殖因子－２３の測定方法及び測定試薬 |
| WO2012055096A1 (zh) * | 2010-10-27 | 2012-05-03 | 温州医学院生物与天然药物开发中心有限公司 | 抗fgf-23抗体的制备方法及用途 |
| US20140294820A1 (en) | 2011-06-24 | 2014-10-02 | University Of Miami | Fibroblast growth factor receptor inhibition for the treatment of disease |
| LT2726511T (lt) | 2011-07-01 | 2019-11-11 | Ngm Biopharmaceuticals Inc | Kompozicijos, panaudojimai ir būdai, skirti metabolinių sutrikimų ir ligų gydymui |
| WO2013027191A1 (en) | 2011-08-25 | 2013-02-28 | Novartis Ag | Methods and compositions using fgf23 fusion polypeptides |
| US9657075B2 (en) | 2012-06-07 | 2017-05-23 | New York University | Chimeric fibroblast growth factor 23 proteins and methods of use |
| AU2013352363B2 (en) | 2012-11-28 | 2018-04-12 | Ngm Biopharmaceuticals, Inc. | Compositions and methods for treatment of metabolic disorders and diseases |
| US9290557B2 (en) | 2012-11-28 | 2016-03-22 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants and fusions of FGF19 polypeptides |
| US9273107B2 (en) | 2012-12-27 | 2016-03-01 | Ngm Biopharmaceuticals, Inc. | Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
| AU2013370404B2 (en) | 2012-12-27 | 2017-11-02 | Ngm Biopharmaceuticals, Inc. | Methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
| US9550820B2 (en) | 2013-02-22 | 2017-01-24 | New York University | Chimeric fibroblast growth factor 23/fibroblast growth factor 19 proteins and methods of use |
| JP6479775B2 (ja) * | 2013-09-20 | 2019-03-06 | ロンザ リミテッドＬｏｎｚａ Ｌｉｍｉｔｅｄ | 細胞の核リプログラミングのための方法 |
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| SI3097122T1 (sl) | 2014-01-24 | 2020-07-31 | Ngm Biopharmaceuticals, Inc. | Protitelesa, ki se vežejo v domeni beta klotho 2, in metode za njihovo uporabo |
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| AU2016284696B2 (en) * | 2015-06-25 | 2021-10-28 | Amyris, Inc. | Maltose dependent degrons, maltose-responsive promoters, stabilization constructs, and their use in production of non-catabolic compounds |
| WO2017019957A2 (en) | 2015-07-29 | 2017-02-02 | Ngm Biopharmaceuticals, Inc. | Binding proteins and methods of use thereof |
| CA3003616C (en) | 2015-11-09 | 2020-07-28 | Ngm Biopharmaceuticals, Inc. | Methods for treatment of bile acid-related disorders |
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| WO1994017810A1 (en) | 1993-02-12 | 1994-08-18 | The Wistar Institute Of Anatomy And Biology | Recombinant cytomegalovirus vaccine |
| EP0708658A4 (en) | 1993-04-16 | 1997-05-21 | Wistar Inst | RECOMBINANT CYTOMEGALOVIRUS VACCINE |
| US5693775A (en) * | 1995-05-12 | 1997-12-02 | The Johns Hopkins University School Of Medicine | Fibroblast growth factor homologous factor-1 (FHF-1) and methods of use |
| US20020102604A1 (en) * | 1999-12-08 | 2002-08-01 | Milne Edwards Jean-Baptiste Dumas | Full-length human cDNAs encoding potentially secreted proteins |
| EP1210418B1 (en) | 1999-06-02 | 2010-08-18 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| CA2490909A1 (en) * | 1999-12-01 | 2001-06-07 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| JP2003518944A (ja) | 2000-01-05 | 2003-06-17 | ザイモジェネティクス，インコーポレイティド | 新規ｆｇｆ相同体ｚｆｇｆ１２ |
| US20030149238A1 (en) | 2000-02-14 | 2003-08-07 | Pankaj Agarwal | Novel compounds |
| CA2398603A1 (en) * | 2000-02-15 | 2001-08-23 | Amgen, Inc. | Fibroblast growth factor-23 molecules and uses thereof |
| AU2001249125A1 (en) * | 2000-03-08 | 2001-09-17 | Chiron Corporation | Human fgf-23 gene and gene expression products |
| WO2002076467A1 (en) * | 2001-03-22 | 2002-10-03 | Genzyme Corporation | Compositions and methods to regulate bone and mineral metabolism |
-
2001
- 2001-07-10 AT AT01952590T patent/ATE461213T1/de not_active IP Right Cessation
- 2001-07-10 AU AU7332301A patent/AU7332301A/xx active Pending
- 2001-07-10 JP JP2002514175A patent/JP2004504063A/ja active Pending
- 2001-07-10 DE DE60141582T patent/DE60141582D1/de not_active Expired - Lifetime
- 2001-07-10 CA CA002418215A patent/CA2418215A1/en not_active Abandoned
- 2001-07-10 KR KR1020097006051A patent/KR20090036151A/ko not_active Ceased
- 2001-07-10 AU AU2001273323A patent/AU2001273323B2/en not_active Expired
- 2001-07-10 EP EP10001442A patent/EP2184296A1/en not_active Withdrawn
- 2001-07-10 WO PCT/US2001/021738 patent/WO2002008271A1/en not_active Ceased
- 2001-07-10 ES ES01952590T patent/ES2340662T3/es not_active Expired - Lifetime
- 2001-07-10 EP EP01952590A patent/EP1303536B1/en not_active Expired - Lifetime
- 2001-07-10 US US09/901,938 patent/US7223563B2/en not_active Expired - Lifetime
- 2001-07-10 CN CN018140572A patent/CN1446227B/zh not_active Expired - Lifetime
-
2003
- 2003-01-18 KR KR1020037000821A patent/KR100924183B1/ko not_active Expired - Lifetime
- 2003-03-04 US US10/379,334 patent/US7314618B2/en not_active Expired - Lifetime
-
2007
- 2007-11-07 US US11/983,137 patent/US7745406B2/en not_active Expired - Fee Related
- 2007-11-07 US US11/983,190 patent/US7947810B2/en not_active Expired - Fee Related
-
2008
- 2008-02-05 JP JP2008025528A patent/JP2008194039A/ja active Pending
-
2011
- 2011-04-11 US US13/084,203 patent/US8586317B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1446227B (zh) | 2011-10-05 |
| US20090311792A1 (en) | 2009-12-17 |
| AU7332301A (en) | 2002-02-05 |
| US20020156001A1 (en) | 2002-10-24 |
| JP2008194039A (ja) | 2008-08-28 |
| EP2184296A1 (en) | 2010-05-12 |
| EP1303536B1 (en) | 2010-03-17 |
| KR100924183B1 (ko) | 2009-10-28 |
| KR20090036151A (ko) | 2009-04-13 |
| US7223563B2 (en) | 2007-05-29 |
| US7314618B2 (en) | 2008-01-01 |
| CN1446227A (zh) | 2003-10-01 |
| DE60141582D1 (de) | 2010-04-29 |
| US20030181379A1 (en) | 2003-09-25 |
| EP1303536A4 (en) | 2005-01-05 |
| US20080241946A1 (en) | 2008-10-02 |
| AU2001273323B2 (en) | 2005-11-10 |
| JP2004504063A (ja) | 2004-02-12 |
| ATE461213T1 (de) | 2010-04-15 |
| US7947810B2 (en) | 2011-05-24 |
| KR20030029111A (ko) | 2003-04-11 |
| US8586317B2 (en) | 2013-11-19 |
| WO2002008271A1 (en) | 2002-01-31 |
| US20120064544A1 (en) | 2012-03-15 |
| CA2418215A1 (en) | 2002-01-31 |
| US7745406B2 (en) | 2010-06-29 |
| EP1303536A1 (en) | 2003-04-23 |
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