ES2337167T3 - Derivados de sulfonamida aminoarilos como ligandos funcionales 5ht6. - Google Patents
Derivados de sulfonamida aminoarilos como ligandos funcionales 5ht6. Download PDFInfo
- Publication number
- ES2337167T3 ES2337167T3 ES05813800T ES05813800T ES2337167T3 ES 2337167 T3 ES2337167 T3 ES 2337167T3 ES 05813800 T ES05813800 T ES 05813800T ES 05813800 T ES05813800 T ES 05813800T ES 2337167 T3 ES2337167 T3 ES 2337167T3
- Authority
- ES
- Spain
- Prior art keywords
- methylpiperidin
- amino
- benzenesulfonyl
- alkyl
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Semiconductor Integrated Circuits (AREA)
- Insulated Gate Type Field-Effect Transistor (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| INCH1127/05 | 2005-08-12 | ||
| IN1127CH2005 | 2005-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2337167T3 true ES2337167T3 (es) | 2010-04-21 |
Family
ID=36130030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES05813800T Expired - Lifetime ES2337167T3 (es) | 2005-08-12 | 2005-10-26 | Derivados de sulfonamida aminoarilos como ligandos funcionales 5ht6. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7998981B2 (pt) |
| EP (1) | EP1919896B1 (pt) |
| JP (1) | JP5091138B2 (pt) |
| KR (1) | KR101016972B1 (pt) |
| CN (1) | CN101258144B (pt) |
| AT (1) | ATE452885T1 (pt) |
| AU (1) | AU2005335620B2 (pt) |
| BR (1) | BRPI0520579B8 (pt) |
| CA (1) | CA2618636C (pt) |
| CY (1) | CY1110276T1 (pt) |
| DE (1) | DE602005018554D1 (pt) |
| DK (1) | DK1919896T3 (pt) |
| EA (1) | EA013875B1 (pt) |
| ES (1) | ES2337167T3 (pt) |
| MX (1) | MX2008002018A (pt) |
| NO (1) | NO340511B1 (pt) |
| NZ (1) | NZ566495A (pt) |
| PL (1) | PL1919896T3 (pt) |
| PT (1) | PT1919896E (pt) |
| SI (1) | SI1919896T1 (pt) |
| WO (1) | WO2007020652A1 (pt) |
| ZA (1) | ZA200801276B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2009006077A (es) | 2007-01-08 | 2009-06-17 | Suven Life Sciences Ltd | Compuestos de 5-(heterociclil)alquil-n-(arilsulfonil)indol y su uso como ligandos de la 5-hidroxitriptamina6. |
| EA016594B1 (ru) | 2007-05-03 | 2012-06-29 | Сувен Лайф Сайенсиз Лимитед | Производные 1-(аминоалкоксиарилсульфонил)индола в качестве 5-нтлигандов |
| US7964627B2 (en) * | 2007-10-26 | 2011-06-21 | Suven Life Sciences Limited | Amino arylsulfonamide compounds and their use as 5-HT6 ligands |
| US8318725B2 (en) | 2008-09-17 | 2012-11-27 | Suven Life Sciences Limited | Aryl indolyl sulfonamide compounds and their use as 5-HT6 ligands |
| JP5628937B2 (ja) * | 2010-01-05 | 2014-11-19 | スベン ライフ サイエンシズ リミティド | ５−ｈｔ６受容体リガンドとしてのスルホン化合物 |
| CN102153884B (zh) * | 2011-02-16 | 2013-06-19 | 连云港清泰化工有限公司 | 一种墨水型染料及其制备方法与用途 |
| EP3083588B1 (en) | 2013-12-20 | 2020-12-09 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic compounds and their application in pharmaceuticals |
| EP3166924B1 (en) | 2014-07-08 | 2019-02-20 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic derivatives and pharmaceutical applications thereof |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT69705A (en) * | 1991-11-25 | 1995-09-28 | Pfizer | Indole derivatives |
| DZ2376A1 (fr) | 1996-12-19 | 2002-12-28 | Smithkline Beecham Plc | Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant. |
| EP0994862B1 (en) * | 1997-07-11 | 2005-06-01 | SmithKline Beecham plc | Sulphonamide derivatives being 5-ht6 receptor antagonists and process for their preparation |
| GB9801392D0 (en) | 1998-01-22 | 1998-03-18 | Smithkline Beecham Plc | Novel compounds |
| GB9803411D0 (en) | 1998-02-18 | 1998-04-15 | Smithkline Beecham Plc | Novel compounds |
| GB9926302D0 (en) | 1999-11-05 | 2000-01-12 | Smithkline Beecham Plc | Novel compounds |
| ATE327232T1 (de) * | 2000-12-22 | 2006-06-15 | Wyeth Corp | Heterozyklylalkylindole oder -azaindole als 5- hydroxytryptamine-6 liganden |
| CN100439370C (zh) | 2001-02-08 | 2008-12-03 | 记忆药物公司 | 作为磷酸二酯酶4抑制剂的三氟甲基嘌呤 |
| BR0211561A (pt) * | 2001-08-03 | 2004-11-30 | Upjohn Co | Compostos e composições de 5-arilsulfonil indóis tendo afinidade para receptor 5-ht6 e seus usos |
| WO2003065046A2 (en) | 2002-02-01 | 2003-08-07 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with a new human 5-ht6 receptor |
| AU2003244452A1 (en) | 2002-02-05 | 2003-09-02 | Glaxo Group Limited | Method of promoting neuronal growth |
| JP4467307B2 (ja) * | 2002-02-22 | 2010-05-26 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | ５−ｈｔ受容体アンタゴニストとしてのピリジルスルホン誘導体 |
| CA2485725A1 (en) * | 2002-06-05 | 2003-12-18 | F. Hoffmann-La Roche Ag | 1-sulfonyl-4-aminoalkoxy indole derivatives as 5-ht6-receptor modulators for the treatment of cns-disorders |
| RU2324693C2 (ru) | 2002-10-18 | 2008-05-20 | Ф.Хоффманн-Ля Рош Аг | 4-пиперазинилбензолсульфонилиндолы, характеризующиеся сродством к рецептору 5-нт6 |
| MXPA05005700A (es) | 2002-11-28 | 2005-08-16 | Suven Life Sciences Ltd | N-arilsulfonil-3-aminoalcoxiindoles. |
| JP4559230B2 (ja) | 2002-11-28 | 2010-10-06 | スベン ライフ サイエンシズ リミティド | セロトニン受容体に対する親和性を有する新規ｎ−アリールスルホニル−３−置換されたインドール、その調製方法、それを含有する医薬組成物 |
| AU2003292508A1 (en) | 2002-11-28 | 2004-06-18 | Suven Life Sciences Limited | N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands |
| EA009367B1 (ru) | 2002-12-18 | 2007-12-28 | Сувен Лайф Сайенсиз Лимитед | ПРОИЗВОДНЫЕ 5-ТИА-5-ДИОКСО-4b-АЗАИНДЕНО[2,1-a]ИНДЕНА, ОБЛАДАЮЩИЕ АФФИННОСТЬЮ К РЕЦЕПТОРУ СЕРОТОНИНА |
| ATE551997T1 (de) * | 2003-09-12 | 2012-04-15 | Merck Serono Sa | Sulfonamid-derivate zur behandlung von diabetes |
-
2005
- 2005-10-26 BR BRPI0520579A patent/BRPI0520579B8/pt not_active IP Right Cessation
- 2005-10-26 MX MX2008002018A patent/MX2008002018A/es active IP Right Grant
- 2005-10-26 SI SI200530928T patent/SI1919896T1/sl unknown
- 2005-10-26 PT PT05813800T patent/PT1919896E/pt unknown
- 2005-10-26 CA CA2618636A patent/CA2618636C/en not_active Expired - Fee Related
- 2005-10-26 AU AU2005335620A patent/AU2005335620B2/en not_active Ceased
- 2005-10-26 JP JP2008525723A patent/JP5091138B2/ja not_active Expired - Fee Related
- 2005-10-26 ES ES05813800T patent/ES2337167T3/es not_active Expired - Lifetime
- 2005-10-26 KR KR1020087005968A patent/KR101016972B1/ko not_active Expired - Fee Related
- 2005-10-26 DK DK05813800.9T patent/DK1919896T3/da active
- 2005-10-26 NZ NZ566495A patent/NZ566495A/en not_active IP Right Cessation
- 2005-10-26 WO PCT/IN2005/000345 patent/WO2007020652A1/en not_active Ceased
- 2005-10-26 EP EP05813800A patent/EP1919896B1/en not_active Expired - Lifetime
- 2005-10-26 CN CN2005800515505A patent/CN101258144B/zh not_active Expired - Fee Related
- 2005-10-26 AT AT05813800T patent/ATE452885T1/de active
- 2005-10-26 EA EA200800573A patent/EA013875B1/ru not_active IP Right Cessation
- 2005-10-26 DE DE602005018554T patent/DE602005018554D1/de not_active Expired - Lifetime
- 2005-10-26 US US11/990,383 patent/US7998981B2/en not_active Expired - Fee Related
- 2005-10-26 PL PL05813800T patent/PL1919896T3/pl unknown
-
2008
- 2008-02-06 ZA ZA200801276A patent/ZA200801276B/xx unknown
- 2008-02-08 NO NO20080705A patent/NO340511B1/no not_active IP Right Cessation
-
2010
- 2010-02-04 CY CY20101100110T patent/CY1110276T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR101016972B1 (ko) | 2011-02-25 |
| CA2618636C (en) | 2011-01-18 |
| EP1919896A1 (en) | 2008-05-14 |
| WO2007020652A1 (en) | 2007-02-22 |
| HK1116796A1 (en) | 2009-01-02 |
| US20100168168A1 (en) | 2010-07-01 |
| CA2618636A1 (en) | 2007-02-22 |
| MX2008002018A (es) | 2008-03-27 |
| US7998981B2 (en) | 2011-08-16 |
| ATE452885T1 (de) | 2010-01-15 |
| EP1919896B1 (en) | 2009-12-23 |
| AU2005335620A1 (en) | 2007-02-22 |
| BRPI0520579B8 (pt) | 2021-05-25 |
| EA013875B1 (ru) | 2010-08-30 |
| PT1919896E (pt) | 2010-02-26 |
| SI1919896T1 (sl) | 2010-04-30 |
| NO20080705L (no) | 2008-05-06 |
| KR20080039984A (ko) | 2008-05-07 |
| CN101258144A (zh) | 2008-09-03 |
| AU2005335620B2 (en) | 2009-12-10 |
| DE602005018554D1 (de) | 2010-02-04 |
| JP5091138B2 (ja) | 2012-12-05 |
| JP2009504633A (ja) | 2009-02-05 |
| ZA200801276B (en) | 2009-02-25 |
| CY1110276T1 (el) | 2015-01-14 |
| NZ566495A (en) | 2010-06-25 |
| PL1919896T3 (pl) | 2010-05-31 |
| NO340511B1 (no) | 2017-05-02 |
| DK1919896T3 (da) | 2010-04-19 |
| BRPI0520579A2 (pt) | 2009-11-10 |
| CN101258144B (zh) | 2012-05-30 |
| EA200800573A1 (ru) | 2008-08-29 |
| BRPI0520579B1 (pt) | 2019-08-06 |
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