DE602005018554D1 - Aminoarylsulfonamidderivate als funktionelle 5-ht6-liganden - Google Patents
Aminoarylsulfonamidderivate als funktionelle 5-ht6-ligandenInfo
- Publication number
- DE602005018554D1 DE602005018554D1 DE602005018554T DE602005018554T DE602005018554D1 DE 602005018554 D1 DE602005018554 D1 DE 602005018554D1 DE 602005018554 T DE602005018554 T DE 602005018554T DE 602005018554 T DE602005018554 T DE 602005018554T DE 602005018554 D1 DE602005018554 D1 DE 602005018554D1
- Authority
- DE
- Germany
- Prior art keywords
- derivatives
- aminoarylsulfonamide
- ligands
- functional
- receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Semiconductor Integrated Circuits (AREA)
- Insulated Gate Type Field-Effect Transistor (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1127CH2005 | 2005-08-12 | ||
| PCT/IN2005/000345 WO2007020652A1 (en) | 2005-08-12 | 2005-10-26 | Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602005018554D1 true DE602005018554D1 (de) | 2010-02-04 |
Family
ID=36130030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005018554T Active DE602005018554D1 (de) | 2005-08-12 | 2005-10-26 | Aminoarylsulfonamidderivate als funktionelle 5-ht6-liganden |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7998981B2 (de) |
| EP (1) | EP1919896B1 (de) |
| JP (1) | JP5091138B2 (de) |
| KR (1) | KR101016972B1 (de) |
| CN (1) | CN101258144B (de) |
| AT (1) | ATE452885T1 (de) |
| AU (1) | AU2005335620B2 (de) |
| BR (1) | BRPI0520579B8 (de) |
| CA (1) | CA2618636C (de) |
| CY (1) | CY1110276T1 (de) |
| DE (1) | DE602005018554D1 (de) |
| DK (1) | DK1919896T3 (de) |
| EA (1) | EA013875B1 (de) |
| ES (1) | ES2337167T3 (de) |
| HK (1) | HK1116796A1 (de) |
| MX (1) | MX2008002018A (de) |
| NO (1) | NO340511B1 (de) |
| NZ (1) | NZ566495A (de) |
| PL (1) | PL1919896T3 (de) |
| PT (1) | PT1919896E (de) |
| SI (1) | SI1919896T1 (de) |
| WO (1) | WO2007020652A1 (de) |
| ZA (1) | ZA200801276B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8470830B2 (en) | 2007-01-08 | 2013-06-25 | Suven Life Sciences Limited | 5-(heterocyclyl)alkyl-N-(arylsulfonyl)indole compounds and their use as 5-HT6 ligands |
| ATE513810T1 (de) * | 2007-05-03 | 2011-07-15 | Suven Life Sciences Ltd | Aminoalkoxy-aryl-sulfonamidverbindungen und ihre verwendung als 5-ht6-liganden |
| EA017154B1 (ru) * | 2007-10-26 | 2012-10-30 | Сувен Лайф Сайенсиз Лимитед | Аминоарилсульфонамидные соединения и их применение в качестве 5-нтлигандов |
| WO2010032257A1 (en) * | 2008-09-17 | 2010-03-25 | Suven Life Sciences Limited | Aryl indolyl sulfonamide compounds and their use as 5-ht6 ligands |
| DK2521714T3 (en) * | 2010-01-05 | 2015-10-19 | Suven Life Sciences Ltd | Aromatic sulfone compositions useful in the treatment of central nervous disorders |
| CN102153884B (zh) * | 2011-02-16 | 2013-06-19 | 连云港清泰化工有限公司 | 一种墨水型染料及其制备方法与用途 |
| JP6454346B2 (ja) | 2013-12-20 | 2019-01-16 | サンシャイン・レイク・ファーマ・カンパニー・リミテッドＳｕｎｓｈｉｎｅ Ｌａｋｅ Ｐｈａｒｍａ Ｃｏ．，Ｌｔｄ． | 芳香族複素環式化合物及び医薬におけるその応用 |
| JP6515175B2 (ja) | 2014-07-08 | 2019-05-15 | サンシャイン・レイク・ファーマ・カンパニー・リミテッドＳｕｎｓｈｉｎｅ Ｌａｋｅ Ｐｈａｒｍａ Ｃｏ．，Ｌｔｄ． | 芳香族ヘテロ環誘導体及びその医薬的適用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2143992T3 (es) * | 1991-11-25 | 2000-06-01 | Pfizer | Derivados de 5-(hetero- o carbociclilamino)-indol, su preparacion y uso como 5-ht1 agonistas. |
| DZ2376A1 (fr) | 1996-12-19 | 2002-12-28 | Smithkline Beecham Plc | Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant. |
| EP0994862B1 (de) * | 1997-07-11 | 2005-06-01 | SmithKline Beecham plc | Sulfonamid-derivate als 5-ht6 receptor antagonisten und verfahren zu ihrer herstellung |
| GB9801392D0 (en) | 1998-01-22 | 1998-03-18 | Smithkline Beecham Plc | Novel compounds |
| GB9803411D0 (en) | 1998-02-18 | 1998-04-15 | Smithkline Beecham Plc | Novel compounds |
| GB9926302D0 (en) | 1999-11-05 | 2000-01-12 | Smithkline Beecham Plc | Novel compounds |
| CN1492863A (zh) * | 2000-12-22 | 2004-04-28 | 作为5-羟色胺-6配基的杂环基烷基-吲哚或氮杂吲哚化合物 | |
| BR0207302A (pt) | 2001-02-08 | 2004-02-10 | Memory Pharm Corp | Trifluorometilpurinas como inibidores da fosfodiesterase 4 |
| MXPA04001089A (es) * | 2001-08-03 | 2004-05-20 | Upjohn Co | 5-arilsulfonil indoles que tienen afinidad por el receptor de 5-ht. |
| EP1472544A2 (de) | 2002-02-01 | 2004-11-03 | Bayer HealthCare AG | Diagnostika und therapeutika gegen mit einem neuen menschlichen 5-ht6-rezeptor assoziierten krankheiten |
| WO2003066056A1 (en) | 2002-02-05 | 2003-08-14 | Glaxo Group Limited | Method of promoting neuronal growth |
| MXPA04008097A (es) | 2002-02-22 | 2004-11-26 | Upjohn Co | Derivados de piridilsulfona como antagonistas del receptor 5-ht. |
| CN1293053C (zh) * | 2002-06-05 | 2007-01-03 | 弗·哈夫曼-拉罗切有限公司 | 作为5－ht6－受体调节剂用于治疗cns－病症的1－磺酰基－4－氨基烷氧基吲哚衍生物 |
| KR20050073560A (ko) * | 2002-10-18 | 2005-07-14 | 에프. 호프만-라 로슈 아게 | 5-ｈｔ6 수용체 친화성을 갖는 4-피페라진일 벤젠설폰일인돌 |
| AU2003285759B2 (en) | 2002-11-28 | 2010-01-28 | Suven Life Sciences Limited | N-arylsulfonyl-3-aminoalkoxyindoles |
| WO2004048331A1 (en) | 2002-11-28 | 2004-06-10 | Suven Life Sciences Limited | N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands |
| KR100818508B1 (ko) | 2002-11-28 | 2008-03-31 | 수벤 라이프 사이언시스 리미티드 | 세로토닌 수용체 친화력을 가지는 엔-아릴술포닐-3-치환인돌, 그 제조방법 및 그를 포함하는 약제학적 조성물 |
| PT1581538E (pt) | 2002-12-18 | 2007-05-31 | Suven Life Sciences Ltd | Indolos tetracíclicos substituidos na posição 3 que possuem afinidade pelo receptor de serotonina. |
| ES2385219T3 (es) * | 2003-09-12 | 2012-07-19 | Merck Serono Sa | Derivados de sulfonamida para el tratamiento de diabetes |
-
2005
- 2005-10-26 MX MX2008002018A patent/MX2008002018A/es active IP Right Grant
- 2005-10-26 KR KR1020087005968A patent/KR101016972B1/ko active IP Right Grant
- 2005-10-26 CN CN2005800515505A patent/CN101258144B/zh not_active Expired - Fee Related
- 2005-10-26 ES ES05813800T patent/ES2337167T3/es active Active
- 2005-10-26 AU AU2005335620A patent/AU2005335620B2/en not_active Ceased
- 2005-10-26 EP EP05813800A patent/EP1919896B1/de active Active
- 2005-10-26 WO PCT/IN2005/000345 patent/WO2007020652A1/en active Application Filing
- 2005-10-26 DK DK05813800.9T patent/DK1919896T3/da active
- 2005-10-26 SI SI200530928T patent/SI1919896T1/sl unknown
- 2005-10-26 US US11/990,383 patent/US7998981B2/en not_active Expired - Fee Related
- 2005-10-26 EA EA200800573A patent/EA013875B1/ru not_active IP Right Cessation
- 2005-10-26 AT AT05813800T patent/ATE452885T1/de active
- 2005-10-26 BR BRPI0520579A patent/BRPI0520579B8/pt not_active IP Right Cessation
- 2005-10-26 DE DE602005018554T patent/DE602005018554D1/de active Active
- 2005-10-26 NZ NZ566495A patent/NZ566495A/en not_active IP Right Cessation
- 2005-10-26 PL PL05813800T patent/PL1919896T3/pl unknown
- 2005-10-26 PT PT05813800T patent/PT1919896E/pt unknown
- 2005-10-26 JP JP2008525723A patent/JP5091138B2/ja not_active Expired - Fee Related
- 2005-10-26 CA CA2618636A patent/CA2618636C/en not_active Expired - Fee Related
-
2008
- 2008-02-06 ZA ZA200801276A patent/ZA200801276B/xx unknown
- 2008-02-08 NO NO20080705A patent/NO340511B1/no not_active IP Right Cessation
- 2008-10-15 HK HK08111412.9A patent/HK1116796A1/xx not_active IP Right Cessation
-
2010
- 2010-02-04 CY CY20101100110T patent/CY1110276T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US7998981B2 (en) | 2011-08-16 |
| CA2618636A1 (en) | 2007-02-22 |
| NO20080705L (no) | 2008-05-06 |
| AU2005335620A1 (en) | 2007-02-22 |
| ATE452885T1 (de) | 2010-01-15 |
| PL1919896T3 (pl) | 2010-05-31 |
| HK1116796A1 (en) | 2009-01-02 |
| US20100168168A1 (en) | 2010-07-01 |
| CA2618636C (en) | 2011-01-18 |
| BRPI0520579B8 (pt) | 2021-05-25 |
| BRPI0520579B1 (pt) | 2019-08-06 |
| EA013875B1 (ru) | 2010-08-30 |
| SI1919896T1 (sl) | 2010-04-30 |
| BRPI0520579A2 (pt) | 2009-11-10 |
| CN101258144A (zh) | 2008-09-03 |
| EP1919896A1 (de) | 2008-05-14 |
| DK1919896T3 (da) | 2010-04-19 |
| NO340511B1 (no) | 2017-05-02 |
| ZA200801276B (en) | 2009-02-25 |
| PT1919896E (pt) | 2010-02-26 |
| WO2007020652A1 (en) | 2007-02-22 |
| EA200800573A1 (ru) | 2008-08-29 |
| EP1919896B1 (de) | 2009-12-23 |
| CN101258144B (zh) | 2012-05-30 |
| JP2009504633A (ja) | 2009-02-05 |
| KR20080039984A (ko) | 2008-05-07 |
| MX2008002018A (es) | 2008-03-27 |
| AU2005335620B2 (en) | 2009-12-10 |
| NZ566495A (en) | 2010-06-25 |
| KR101016972B1 (ko) | 2011-02-25 |
| CY1110276T1 (el) | 2015-01-14 |
| ES2337167T3 (es) | 2010-04-21 |
| JP5091138B2 (ja) | 2012-12-05 |
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| TH95735A (th) | อนุพันธ์ 3-ซัลโฟนิลอินดาโซลที่ถูกแทนที่เป็นลิแกนด์ 5-ไฮดรอกซีทริปทามีน-6 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |