NO20080705L - Aminoaryl Sulphonamide Derivatives as functional 5-HT6 Ligands - Google Patents
Aminoaryl Sulphonamide Derivatives as functional 5-HT6 LigandsInfo
- Publication number
- NO20080705L NO20080705L NO20080705A NO20080705A NO20080705L NO 20080705 L NO20080705 L NO 20080705L NO 20080705 A NO20080705 A NO 20080705A NO 20080705 A NO20080705 A NO 20080705A NO 20080705 L NO20080705 L NO 20080705L
- Authority
- NO
- Norway
- Prior art keywords
- sulphonamide derivatives
- ligands
- functional
- aminoaryl
- aminoaryl sulphonamide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Abstract
Det beskrives aminoarylsulfonamidderivater med formel (I) som kan anvendes ved behandling av en CNS-forstyrrelse relatert til eller påvirket av 5-HT6-reseptoren. Den farmakologiske profil for disse forbindelser inkluderer høy affinitetsbinding med 5-HT6-reseptoren sammen med god selektivitet mot reseptoren. Det beskrives også stereoisomerer, salter, metoder for fremstilling og medikamenter inneholdende disse aminoarylsulfonamidderivater.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1127CH2005 | 2005-08-12 | ||
PCT/IN2005/000345 WO2007020652A1 (en) | 2005-08-12 | 2005-10-26 | Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands. |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20080705L true NO20080705L (no) | 2008-05-06 |
NO340511B1 NO340511B1 (no) | 2017-05-02 |
Family
ID=36130030
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20080705A NO340511B1 (no) | 2005-08-12 | 2008-02-08 | Aminoarylsulfonamidderivater som funksjonelle 5-ht6 ligander |
Country Status (23)
Country | Link |
---|---|
US (1) | US7998981B2 (no) |
EP (1) | EP1919896B1 (no) |
JP (1) | JP5091138B2 (no) |
KR (1) | KR101016972B1 (no) |
CN (1) | CN101258144B (no) |
AT (1) | ATE452885T1 (no) |
AU (1) | AU2005335620B2 (no) |
BR (1) | BRPI0520579B8 (no) |
CA (1) | CA2618636C (no) |
CY (1) | CY1110276T1 (no) |
DE (1) | DE602005018554D1 (no) |
DK (1) | DK1919896T3 (no) |
EA (1) | EA013875B1 (no) |
ES (1) | ES2337167T3 (no) |
HK (1) | HK1116796A1 (no) |
MX (1) | MX2008002018A (no) |
NO (1) | NO340511B1 (no) |
NZ (1) | NZ566495A (no) |
PL (1) | PL1919896T3 (no) |
PT (1) | PT1919896E (no) |
SI (1) | SI1919896T1 (no) |
WO (1) | WO2007020652A1 (no) |
ZA (1) | ZA200801276B (no) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0718737A2 (pt) | 2007-01-08 | 2014-03-25 | Suven Life Sciences Ltd | "composto, processo para a preparação de um composto, método para o tratamento de uma desordem do sistema nervoso central, composição farmacêutica, uso do composto, método para testar antagonistas e antagonistas com seletividade para o receptor 5-ht6, e método de tratamento" |
WO2008136017A1 (en) * | 2007-05-03 | 2008-11-13 | Suven Life Sciences Limited | Aminoalkoxy aryl sulfonamide compounds and their use as 5-ht6 ligands |
NZ585374A (en) | 2007-10-26 | 2011-09-30 | Suven Life Sciences Ltd | Amino arylsulfonamide compounds for treating disorders related to 5-HT6 receptor functions |
WO2010032257A1 (en) * | 2008-09-17 | 2010-03-25 | Suven Life Sciences Limited | Aryl indolyl sulfonamide compounds and their use as 5-ht6 ligands |
ES2552463T3 (es) * | 2010-01-05 | 2015-11-30 | Suven Life Sciences Limited | Compuestos aromáticos de sulfona útiles para el tratamiento de enfermedades del sistema nervioso central |
CN102153884B (zh) * | 2011-02-16 | 2013-06-19 | 连云港清泰化工有限公司 | 一种墨水型染料及其制备方法与用途 |
JP6454346B2 (ja) | 2013-12-20 | 2019-01-16 | サンシャイン・レイク・ファーマ・カンパニー・リミテッドSunshine Lake Pharma Co.,Ltd. | 芳香族複素環式化合物及び医薬におけるその応用 |
SG11201610407QA (en) | 2014-07-08 | 2017-01-27 | Sunshine Lake Pharma Co Ltd | Aromatic heterocyclic derivatives and pharmaceutical applications thereof |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69230803T2 (de) * | 1991-11-25 | 2000-12-07 | Pfizer | 5-(hetero- oder carbocyclylamino)-indol derivate, deren herstellung und deren verwendung als 5-ht1 agonisten |
DZ2376A1 (fr) | 1996-12-19 | 2002-12-28 | Smithkline Beecham Plc | Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant. |
TR200000073T2 (tr) | 1997-07-11 | 2000-06-21 | Smithkline Beecham P.L.C. | 5-HT6 Reseptör antagonistleri olan sülfonamid türevleri ve bunların hazırlanma prosesi |
GB9801392D0 (en) | 1998-01-22 | 1998-03-18 | Smithkline Beecham Plc | Novel compounds |
GB9803411D0 (en) | 1998-02-18 | 1998-04-15 | Smithkline Beecham Plc | Novel compounds |
GB9926302D0 (en) | 1999-11-05 | 2000-01-12 | Smithkline Beecham Plc | Novel compounds |
ES2264994T3 (es) * | 2000-12-22 | 2007-02-01 | Wyeth | Compuestos heterociclilalquilindol o -azaindol como ligandos de 5-hidroxitriptamina-6. |
KR100863622B1 (ko) | 2001-02-08 | 2008-10-15 | 메모리 파마슈티칼스 코포레이션 | 포스포디에스테라제 4 억제제로서의 트리플루오로메틸푸린 |
CA2452743A1 (en) * | 2001-08-03 | 2003-02-13 | Pharmacia & Upjohn Company | 5-arylsulfonyl indoles having 5-ht6 receptor affinity |
WO2003065046A2 (en) | 2002-02-01 | 2003-08-07 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with a new human 5-ht6 receptor |
EP1471912A1 (en) | 2002-02-05 | 2004-11-03 | Glaxo Group Limited | Method of promoting neuronal growth |
JP4467307B2 (ja) * | 2002-02-22 | 2010-05-26 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | 5−ht受容体アンタゴニストとしてのピリジルスルホン誘導体 |
KR100657056B1 (ko) * | 2002-06-05 | 2006-12-13 | 에프. 호프만-라 로슈 아게 | 중추 신경계 장애의 치료를 위한 5-ht6-수용체조절제로서 1-설폰일-4-아미노알콕시 인돌 유도체 |
DE60309498T2 (de) | 2002-10-18 | 2007-08-30 | F. Hoffmann-La Roche Ag | 4-piperazinylbenzolsulfonyl-indole mit 5-ht6 rezeptor-affinität |
WO2004048331A1 (en) | 2002-11-28 | 2004-06-10 | Suven Life Sciences Limited | N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands |
NZ540842A (en) | 2002-11-28 | 2008-05-30 | Suven Life Sciences Ltd | N-arylsulfonyl-3-aminoalkoxyindoles |
SI1581492T1 (sl) | 2002-11-28 | 2008-12-31 | Suven Life Sciences Ltd | N-arilsulfonil-3-substituirani indoli, ki imajo afiniteto za serotoninski receptor, postopek za njihovo pripravo in farmacevtski sestavek, ki jih vsebuje |
EP1581538B1 (en) | 2002-12-18 | 2007-02-28 | Suven Life Sciences Limited | Tetracyclic 3-substituted indoles having serotonin receptor affinity |
CA2534312A1 (en) * | 2003-09-12 | 2005-03-24 | Applied Research Systems Ars Holding N.V. | Sulfonamide derivatives for the treatment of diabetes |
-
2005
- 2005-10-26 CN CN2005800515505A patent/CN101258144B/zh not_active Expired - Fee Related
- 2005-10-26 US US11/990,383 patent/US7998981B2/en not_active Expired - Fee Related
- 2005-10-26 DE DE602005018554T patent/DE602005018554D1/de active Active
- 2005-10-26 CA CA2618636A patent/CA2618636C/en not_active Expired - Fee Related
- 2005-10-26 SI SI200530928T patent/SI1919896T1/sl unknown
- 2005-10-26 EP EP05813800A patent/EP1919896B1/en active Active
- 2005-10-26 PL PL05813800T patent/PL1919896T3/pl unknown
- 2005-10-26 DK DK05813800.9T patent/DK1919896T3/da active
- 2005-10-26 AU AU2005335620A patent/AU2005335620B2/en not_active Ceased
- 2005-10-26 ES ES05813800T patent/ES2337167T3/es active Active
- 2005-10-26 AT AT05813800T patent/ATE452885T1/de active
- 2005-10-26 PT PT05813800T patent/PT1919896E/pt unknown
- 2005-10-26 BR BRPI0520579A patent/BRPI0520579B8/pt not_active IP Right Cessation
- 2005-10-26 MX MX2008002018A patent/MX2008002018A/es active IP Right Grant
- 2005-10-26 EA EA200800573A patent/EA013875B1/ru not_active IP Right Cessation
- 2005-10-26 WO PCT/IN2005/000345 patent/WO2007020652A1/en active Application Filing
- 2005-10-26 KR KR1020087005968A patent/KR101016972B1/ko active IP Right Grant
- 2005-10-26 JP JP2008525723A patent/JP5091138B2/ja not_active Expired - Fee Related
- 2005-10-26 NZ NZ566495A patent/NZ566495A/en not_active IP Right Cessation
-
2008
- 2008-02-06 ZA ZA200801276A patent/ZA200801276B/xx unknown
- 2008-02-08 NO NO20080705A patent/NO340511B1/no not_active IP Right Cessation
- 2008-10-15 HK HK08111412.9A patent/HK1116796A1/xx not_active IP Right Cessation
-
2010
- 2010-02-04 CY CY20101100110T patent/CY1110276T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EA200800573A1 (ru) | 2008-08-29 |
ES2337167T3 (es) | 2010-04-21 |
DE602005018554D1 (de) | 2010-02-04 |
BRPI0520579B1 (pt) | 2019-08-06 |
EP1919896A1 (en) | 2008-05-14 |
NO340511B1 (no) | 2017-05-02 |
CN101258144A (zh) | 2008-09-03 |
BRPI0520579B8 (pt) | 2021-05-25 |
US7998981B2 (en) | 2011-08-16 |
BRPI0520579A2 (pt) | 2009-11-10 |
EA013875B1 (ru) | 2010-08-30 |
NZ566495A (en) | 2010-06-25 |
MX2008002018A (es) | 2008-03-27 |
CA2618636A1 (en) | 2007-02-22 |
WO2007020652A1 (en) | 2007-02-22 |
JP5091138B2 (ja) | 2012-12-05 |
HK1116796A1 (en) | 2009-01-02 |
DK1919896T3 (da) | 2010-04-19 |
CA2618636C (en) | 2011-01-18 |
US20100168168A1 (en) | 2010-07-01 |
PL1919896T3 (pl) | 2010-05-31 |
PT1919896E (pt) | 2010-02-26 |
KR20080039984A (ko) | 2008-05-07 |
AU2005335620B2 (en) | 2009-12-10 |
KR101016972B1 (ko) | 2011-02-25 |
ATE452885T1 (de) | 2010-01-15 |
ZA200801276B (en) | 2009-02-25 |
CY1110276T1 (el) | 2015-01-14 |
EP1919896B1 (en) | 2009-12-23 |
SI1919896T1 (sl) | 2010-04-30 |
AU2005335620A1 (en) | 2007-02-22 |
JP2009504633A (ja) | 2009-02-05 |
CN101258144B (zh) | 2012-05-30 |
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