ES2298402T3 - Eritropoyetina pegilada y diglicosilada. - Google Patents
Eritropoyetina pegilada y diglicosilada. Download PDFInfo
- Publication number
- ES2298402T3 ES2298402T3 ES02777160T ES02777160T ES2298402T3 ES 2298402 T3 ES2298402 T3 ES 2298402T3 ES 02777160 T ES02777160 T ES 02777160T ES 02777160 T ES02777160 T ES 02777160T ES 2298402 T3 ES2298402 T3 ES 2298402T3
- Authority
- ES
- Spain
- Prior art keywords
- erythropoietin
- mutein
- terminal
- glycosylated
- epo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Toxicology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
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| EP01122555 | 2001-09-25 | ||
| EP01122555 | 2001-09-25 |
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| ES2298402T3 true ES2298402T3 (es) | 2008-05-16 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| ES02777160T Expired - Lifetime ES2298402T3 (es) | 2001-09-25 | 2002-09-20 | Eritropoyetina pegilada y diglicosilada. |
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| AR (1) | AR036575A1 (enExample) |
| AU (1) | AU2002338743A1 (enExample) |
| CA (1) | CA2460489C (enExample) |
| DE (1) | DE60224415T2 (enExample) |
| ES (1) | ES2298402T3 (enExample) |
| WO (1) | WO2003029291A2 (enExample) |
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| DE3924746A1 (de) | 1989-07-26 | 1991-01-31 | Behringwerke Ag | Erythropoietin (epo)-peptide und dagegen gerichtete antikoerper |
| CN1057534C (zh) | 1993-08-17 | 2000-10-18 | 柯瑞英-艾格公司 | 促红细胞生成素类似物 |
| DE19535571A1 (de) | 1995-09-14 | 1997-03-20 | Boehringer Mannheim Gmbh | Pharmazeutische Kombinationspräparate und deren Verwendung zur Behandlung von Hämodialysepatienten |
| JP2002531089A (ja) | 1998-11-30 | 2002-09-24 | イーライ・リリー・アンド・カンパニー | 赤血球産生性化合物 |
| PE20010288A1 (es) | 1999-07-02 | 2001-03-07 | Hoffmann La Roche | Derivados de eritropoyetina |
-
2002
- 2002-09-11 US US10/241,356 patent/US6930086B2/en not_active Expired - Lifetime
- 2002-09-20 AU AU2002338743A patent/AU2002338743A1/en not_active Abandoned
- 2002-09-20 DE DE60224415T patent/DE60224415T2/de not_active Expired - Lifetime
- 2002-09-20 CA CA2460489A patent/CA2460489C/en not_active Expired - Lifetime
- 2002-09-20 JP JP2003532536A patent/JP4025727B2/ja not_active Expired - Lifetime
- 2002-09-20 WO PCT/EP2002/010556 patent/WO2003029291A2/en not_active Ceased
- 2002-09-20 CN CNB028187520A patent/CN100365117C/zh not_active Expired - Lifetime
- 2002-09-20 EP EP02777160A patent/EP1432802B1/en not_active Expired - Lifetime
- 2002-09-20 ES ES02777160T patent/ES2298402T3/es not_active Expired - Lifetime
- 2002-09-23 AR ARP020103572A patent/AR036575A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE60224415D1 (de) | 2008-02-14 |
| AR036575A1 (es) | 2004-09-15 |
| DE60224415T2 (de) | 2008-12-18 |
| WO2003029291A3 (en) | 2003-07-24 |
| CN1558952A (zh) | 2004-12-29 |
| CA2460489A1 (en) | 2003-04-10 |
| AU2002338743A1 (en) | 2003-04-14 |
| EP1432802B1 (en) | 2008-01-02 |
| CN100365117C (zh) | 2008-01-30 |
| EP1432802A2 (en) | 2004-06-30 |
| JP4025727B2 (ja) | 2007-12-26 |
| WO2003029291A2 (en) | 2003-04-10 |
| US20030077753A1 (en) | 2003-04-24 |
| US6930086B2 (en) | 2005-08-16 |
| JP2005509609A (ja) | 2005-04-14 |
| CA2460489C (en) | 2011-12-06 |
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