ES2275304T3 - Nuevas composiciones de delta-3 humana y usos diagnosticos y terapeuticos para las mismas. - Google Patents
Nuevas composiciones de delta-3 humana y usos diagnosticos y terapeuticos para las mismas. Download PDFInfo
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- ES2275304T3 ES2275304T3 ES98915305T ES98915305T ES2275304T3 ES 2275304 T3 ES2275304 T3 ES 2275304T3 ES 98915305 T ES98915305 T ES 98915305T ES 98915305 T ES98915305 T ES 98915305T ES 2275304 T3 ES2275304 T3 ES 2275304T3
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83263397A | 1997-04-04 | 1997-04-04 | |
| US832633 | 1997-04-04 | ||
| US08/872,855 US6121045A (en) | 1997-04-04 | 1997-06-11 | Human Delta3 nucleic acid molecules |
| US872855 | 1997-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2275304T3 true ES2275304T3 (es) | 2007-06-01 |
Family
ID=27125549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98915305T Expired - Lifetime ES2275304T3 (es) | 1997-04-04 | 1998-04-06 | Nuevas composiciones de delta-3 humana y usos diagnosticos y terapeuticos para las mismas. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0972041B2 (enExample) |
| JP (1) | JP2001521382A (enExample) |
| AT (1) | ATE342358T1 (enExample) |
| AU (1) | AU6952498A (enExample) |
| CA (1) | CA2285020A1 (enExample) |
| DE (1) | DE69836131T3 (enExample) |
| ES (1) | ES2275304T3 (enExample) |
| WO (1) | WO1998045434A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0861261B9 (en) | 1995-06-28 | 2010-02-24 | Imperial Cancer Research Technology Limited | Nucleotide and protein sequences of vertebrate delta genes and methods based thereon |
| US5780300A (en) * | 1995-09-29 | 1998-07-14 | Yale University | Manipulation of non-terminally differentiated cells using the notch pathway |
| US20060122373A1 (en) | 1997-04-04 | 2006-06-08 | Millennium Pharmaceuticals, Inc. | Delta3, FTHMA-070, Tango85, Tango77, SPOIL,NEOKINE, Tango129 and integrin alpha subunit protein and nucleic acid molecules and uses thereof |
| WO1998051799A1 (en) * | 1997-05-14 | 1998-11-19 | Asahi Kasei Kogyo Kabushiki Kaisha | Novel differentiation inhibitor |
| EP1100899A2 (en) * | 1998-07-27 | 2001-05-23 | Amgen Inc. | Delta-related polypeptides |
| US6703221B1 (en) | 1999-08-19 | 2004-03-09 | Chiron Corporation | Notch receptor ligands and uses thereof |
| JP2003507029A (ja) * | 1999-08-19 | 2003-02-25 | カイロン コーポレイション | Ｎｏｔｃｈレセプターリガンドおよびその使用 |
| GB9927331D0 (en) | 1999-11-18 | 2000-01-12 | Fluorescience Ltd | Assay for measuring enzyme activity in vivo |
| GB9927328D0 (en) | 1999-11-18 | 2000-01-12 | Lorantis Ltd | Immunotherapy |
| US6984522B2 (en) | 2000-08-03 | 2006-01-10 | Regents Of The University Of Michigan | Isolation and use of solid tumor stem cells |
| US8044259B2 (en) | 2000-08-03 | 2011-10-25 | The Regents Of The University Of Michigan | Determining the capability of a test compound to affect solid tumor stem cells |
| EP1438402A2 (en) * | 2001-08-22 | 2004-07-21 | Galapagos Genomics N.V. | Modulators of bone homeostasis identified in a high-throughput screen |
| JP2003245084A (ja) | 2001-12-20 | 2003-09-02 | Morinaga Milk Ind Co Ltd | 脳梁又は精子の形成不全の診断及び治療に有用な新規遺伝子、並びにその用途 |
| US8048418B2 (en) | 2004-10-29 | 2011-11-01 | Regeneron Pharmaceuticals, Inc. | Therapeutic methods for inhibiting tumor growth with combination of Dll4 antagonists and VEGF antagonists |
| US7906116B2 (en) | 2005-09-01 | 2011-03-15 | Parkash Gill | Methods for using and identifying modulators of Delta-like 4 |
| US7723477B2 (en) | 2005-10-31 | 2010-05-25 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth |
| PT2500360E (pt) | 2005-10-31 | 2015-10-15 | Oncomed Pharm Inc | Composições e métodos para diagnóstico e tratamento do cancro |
| CA2654000A1 (en) | 2006-06-06 | 2008-05-22 | Genentech, Inc. | Anti-dll4 antibodies and methods using same |
| US7750124B2 (en) | 2006-09-29 | 2010-07-06 | Oncomed Pharmaceuticals, Inc. | Anti-human DLL4 antibodies and compositions |
| NO347649B1 (no) | 2006-12-14 | 2024-02-12 | Regeneron Pharma | Humant antistoff eller antistoff fragment som spesifikt binder human deltaliknende ligand 4 (hDII4), nukleinsyremolekyl som koder for slike og vektor og vert-vektorsystemer, samt fremgangsmåte for fremstilling, sammensetning og anvendelse. |
| EP2106439B1 (en) | 2007-01-24 | 2014-11-12 | The Regents of the University of Michigan | Compositions and methods for treating and diagnosing pancreatic cancer |
| MX2011003183A (es) | 2008-09-26 | 2011-04-21 | Oncomed Pharm Inc | Agentes que se unen a receptor encrespado y usos de los mismos. |
| EP2356270B1 (en) | 2008-11-07 | 2016-08-24 | Fabrus Llc | Combinatorial antibody libraries and uses thereof |
| EP3485908B1 (en) | 2009-10-16 | 2021-08-18 | Mereo BioPharma 5, Inc. | Therapeutic combination and use of dll4 antagonist antibodies and anti-hypertensive agents |
| TWI535445B (zh) | 2010-01-12 | 2016-06-01 | 安可美德藥物股份有限公司 | Ｗｎｔ拮抗劑及治療和篩選方法 |
| DK3342786T3 (en) | 2010-01-29 | 2021-09-27 | Chugai Pharmaceutical Co Ltd | Anti-dll3-antistof |
| KR20130043102A (ko) | 2010-04-01 | 2013-04-29 | 온코메드 파마슈티칼스, 인크. | 프리즐드-결합 작용제 및 그의 용도 |
| US8551479B2 (en) | 2010-09-10 | 2013-10-08 | Oncomed Pharmaceuticals, Inc. | Methods for treating melanoma |
| HRP20190044T1 (hr) | 2011-09-23 | 2019-02-22 | Oncomed Pharmaceuticals, Inc. | Agensi koji vežu vegf/dll4 i njihove uporabe |
| HK1212216A1 (en) | 2012-10-23 | 2016-06-10 | Oncomed Pharmaceuticals, Inc. | Methods of treating neuroendocrine tumors using wnt pathway-binding agents |
| AU2013337811A1 (en) | 2012-10-31 | 2015-05-14 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a DLL4 antagonist |
| HK1211887A1 (en) | 2013-02-04 | 2016-06-03 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a wnt pathway inhibitor |
| US9168300B2 (en) | 2013-03-14 | 2015-10-27 | Oncomed Pharmaceuticals, Inc. | MET-binding agents and uses thereof |
| MX382902B (es) | 2014-10-31 | 2025-03-13 | Oncomed Pharm Inc | Inhibidor de la vía noth en combinación con un agente inmunoterapéutico para usarse en el tratamiento de cáncer. |
| WO2017053705A1 (en) | 2015-09-23 | 2017-03-30 | Oncomed Pharmaceuticals, Inc. | Methods and compositions for treatment of cancer |
| WO2019131988A1 (en) | 2017-12-28 | 2019-07-04 | Chugai Seiyaku Kabushiki Kaisha | Cytotoxicity-inducing therapeutic agent |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL101728A (en) | 1991-05-03 | 2007-08-19 | Univ Yale | Human Abandonment and Delta, Restrictive Areas of Effect in Tophoric Proteins, and Methods Based on Them |
| US5786158A (en) | 1992-04-30 | 1998-07-28 | Yale University | Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids |
| EP0861261B9 (en) * | 1995-06-28 | 2010-02-24 | Imperial Cancer Research Technology Limited | Nucleotide and protein sequences of vertebrate delta genes and methods based thereon |
| DE69635899T2 (de) * | 1995-11-17 | 2006-11-23 | Asahi Kasei Kabushiki Kaisha | Polypeptid, das die differenzierung unterdrueckt |
-
1998
- 1998-04-06 EP EP98915305.1A patent/EP0972041B2/en not_active Expired - Lifetime
- 1998-04-06 WO PCT/US1998/006775 patent/WO1998045434A1/en not_active Ceased
- 1998-04-06 CA CA002285020A patent/CA2285020A1/en not_active Abandoned
- 1998-04-06 ES ES98915305T patent/ES2275304T3/es not_active Expired - Lifetime
- 1998-04-06 AU AU69524/98A patent/AU6952498A/en not_active Abandoned
- 1998-04-06 JP JP54299298A patent/JP2001521382A/ja active Pending
- 1998-04-06 AT AT98915305T patent/ATE342358T1/de not_active IP Right Cessation
- 1998-04-06 DE DE69836131.8T patent/DE69836131T3/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69836131T2 (de) | 2007-08-30 |
| ATE342358T1 (de) | 2006-11-15 |
| DE69836131D1 (de) | 2006-11-23 |
| CA2285020A1 (en) | 1998-10-15 |
| DE69836131T3 (de) | 2017-06-14 |
| EP0972041B2 (en) | 2017-01-18 |
| AU6952498A (en) | 1998-10-30 |
| WO1998045434A1 (en) | 1998-10-15 |
| JP2001521382A (ja) | 2001-11-06 |
| EP0972041A1 (en) | 2000-01-19 |
| EP0972041B1 (en) | 2006-10-11 |
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