ES2245807T3 - Quinasa humana de puntos de control, hcds1, composiciones y procedimientos. - Google Patents

Quinasa humana de puntos de control, hcds1, composiciones y procedimientos.

Info

Publication number
ES2245807T3
ES2245807T3 ES98966890T ES98966890T ES2245807T3 ES 2245807 T3 ES2245807 T3 ES 2245807T3 ES 98966890 T ES98966890 T ES 98966890T ES 98966890 T ES98966890 T ES 98966890T ES 2245807 T3 ES2245807 T3 ES 2245807T3
Authority
ES
Spain
Prior art keywords
protein
acid sequence
seq
nucleic acid
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98966890T
Other languages
English (en)
Spanish (es)
Inventor
Walter H. M.-Janssen Pharmaceutica N.V. LUYTEN
Andrew E.-Zeneca Pharmaceuticals PARKER
Clare Mcgowan
Alessandra Blasina
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Application granted granted Critical
Publication of ES2245807T3 publication Critical patent/ES2245807T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Dental Preparations (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
ES98966890T 1997-10-22 1998-10-21 Quinasa humana de puntos de control, hcds1, composiciones y procedimientos. Expired - Lifetime ES2245807T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9722320.0A GB9722320D0 (en) 1997-10-22 1997-10-22 Human cell cycle checkpoint proteins
GB9722320 1997-10-22

Publications (1)

Publication Number Publication Date
ES2245807T3 true ES2245807T3 (es) 2006-01-16

Family

ID=10820925

Family Applications (2)

Application Number Title Priority Date Filing Date
ES98966890T Expired - Lifetime ES2245807T3 (es) 1997-10-22 1998-10-21 Quinasa humana de puntos de control, hcds1, composiciones y procedimientos.
ES98955533T Expired - Lifetime ES2245050T3 (es) 1997-10-22 1998-10-21 Nueva quinasa humana punto de control, hcds1, composiciones y procedimientos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES98955533T Expired - Lifetime ES2245050T3 (es) 1997-10-22 1998-10-21 Nueva quinasa humana punto de control, hcds1, composiciones y procedimientos.

Country Status (13)

Country Link
US (4) US6413755B1 (enExample)
EP (2) EP1025236B1 (enExample)
JP (2) JP4418103B2 (enExample)
AT (2) ATE300619T1 (enExample)
AU (2) AU760544B2 (enExample)
CA (2) CA2308013A1 (enExample)
DE (2) DE69831500T2 (enExample)
DK (2) DK1025236T3 (enExample)
ES (2) ES2245807T3 (enExample)
GB (1) GB9722320D0 (enExample)
IL (2) IL135687A (enExample)
NZ (2) NZ503983A (enExample)
WO (2) WO1999025843A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins
EP1090987A4 (en) * 1998-06-23 2003-05-28 Chugai Pharmaceutical Co Ltd CELL CYCLE REGULATION FACTOR
GB9827430D0 (en) * 1998-12-11 1999-02-03 Ludwig Inst Cancer Res Differential expression in primary breast cancer
US20020038011A1 (en) * 2000-02-18 2002-03-28 Walke D. Wade Novel human kinases and polynucleotides encoding the same
AU2001237599A1 (en) * 2000-03-08 2001-09-17 Zealand Pharma A/S Materials and methods relating to the degradation of cdc25a in response to dna damage
EP1297150A2 (en) * 2000-04-20 2003-04-02 Incyte Genomics, Inc. Human kinases
US6323016B1 (en) 2000-06-09 2001-11-27 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
FR2812945B1 (fr) * 2000-08-10 2002-10-04 Aventis Pharma Sa Utilisation de la proteine grf1 et cellules exprimant la proteine grf1 pour le criblage de molecules
US6372468B1 (en) * 2000-09-14 2002-04-16 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
WO2002048328A2 (en) * 2000-12-14 2002-06-20 Pe Corporation (Ny) Isolated human kinase proteins, their encoding nucleic acid molecules, and uses thereof
US6451538B1 (en) * 2000-12-22 2002-09-17 Isis Pharmaceuticals, Inc. Antisense modulation of CHK2 expression
WO2002051858A2 (en) * 2000-12-22 2002-07-04 Isis Pharmaceuticals, Inc. Antisense modulation of chk2 expression
WO2002059325A2 (en) * 2000-12-27 2002-08-01 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
EP1224942A1 (en) * 2001-01-23 2002-07-24 Bernhard Dr. Nieswandt Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases
KR100697746B1 (ko) 2003-01-09 2007-03-22 화이자 인코포레이티드 키나제 저해제로서의 디아제피노인돌 유도체
CA2536788A1 (en) * 2003-08-29 2005-03-10 Pfizer Inc. Naphthalene carboxamides and their derivatives useful as new anti-angiogenic agents
BRPI0413876A (pt) * 2003-08-29 2006-10-24 Pfizer tienopiridin-fenilacetamidas e seus derivados úteis como agentes antiangiogênicos
US8572169B2 (en) * 2006-08-28 2013-10-29 Myspace, Llc System, apparatus and method for discovery of music within a social network
BRPI0823416A2 (pt) 2007-05-08 2015-06-16 Schering Corp Métodos de tratamento usando formulações intravenosas compreendendo temozolomida.
JP5576370B2 (ja) * 2008-08-06 2014-08-20 ファイザー・インク Chk−1阻害剤としての6置換2−ヘテロシクリルアミノピラジン化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443962A (en) * 1993-06-04 1995-08-22 Mitotix, Inc. Methods of identifying inhibitors of cdc25 phosphatase
US5674748A (en) * 1995-03-14 1997-10-07 Thomas Jefferson University Human cyclin-dependent kinase-like proteins and methods of using the same
IL121306A0 (en) * 1995-11-16 1998-01-04 Icos Corp Cell cycle checkpoint pik-related kinase materials and methods
US5744349A (en) * 1996-03-05 1998-04-28 Washington University DNA sequences encoding human Myt1 kinase
US6218109B1 (en) * 1997-09-05 2001-04-17 Baylor College Of Medicine Mammalian checkpoint genes and proteins
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins

Also Published As

Publication number Publication date
US6531312B1 (en) 2003-03-11
CA2306492A1 (en) 1999-05-27
EP1025237B1 (en) 2005-09-07
US6413755B1 (en) 2002-07-02
US6943013B2 (en) 2005-09-13
IL135687A (en) 2007-07-04
DK1025237T3 (da) 2005-11-28
AU2612699A (en) 1999-06-07
EP1025236B1 (en) 2005-07-27
AU1232299A (en) 1999-05-10
ATE300619T1 (de) 2005-08-15
WO1999025843A2 (en) 1999-05-27
US7414020B2 (en) 2008-08-19
DE69831007D1 (de) 2005-09-01
AU752617B2 (en) 2002-09-26
GB9722320D0 (en) 1997-12-17
US20030017160A1 (en) 2003-01-23
NZ503965A (en) 2002-03-28
IL135687A0 (en) 2001-05-20
ES2245050T3 (es) 2005-12-16
EP1025237A2 (en) 2000-08-09
US20050180981A1 (en) 2005-08-18
WO1999025843A3 (en) 1999-08-05
IL135688A0 (en) 2001-05-20
IL135688A (en) 2010-04-29
JP4418103B2 (ja) 2010-02-17
DE69831500D1 (de) 2005-10-13
WO1999020747A2 (en) 1999-04-29
JP4261050B2 (ja) 2009-04-30
CA2306492C (en) 2014-03-25
EP1025236A2 (en) 2000-08-09
DK1025236T3 (da) 2005-10-24
ATE304052T1 (de) 2005-09-15
DE69831500T2 (de) 2006-06-14
JP2001523461A (ja) 2001-11-27
WO1999020747A3 (en) 1999-07-01
CA2308013A1 (en) 1999-04-29
DE69831007T2 (de) 2006-04-20
NZ503983A (en) 2002-03-28
AU760544B2 (en) 2003-05-15
JP2001520037A (ja) 2001-10-30

Similar Documents

Publication Publication Date Title
ES2245807T3 (es) Quinasa humana de puntos de control, hcds1, composiciones y procedimientos.
Kharbanda et al. Activation of the c-Abl tyrosine kinase in the stress response to DMA-damaging agents
ES2200526T5 (es) Peptidos antigenicos derivados de telomerasa.
ES2248997T3 (es) Proteina-quinasas ste20-relacionadas.
US6534056B1 (en) Therapeutic and diagnostic uses of protein tyrosine phosphatase TC-PTP
US20030166025A1 (en) Antiproliferative Sgk reagents and methods
Elzen et al. Resisting arrest: recovery from checkpoint arrest through dephosphorylation of Chk1 by PP1
ES2327815T3 (es) 18477, proteina quinasa humana y usos de la misma.
WO1997042212A1 (en) Sok-1 and methods of use
JP2001517430A (ja) ヒトSte20様ストレス活性化セリン/スレオニンキナーゼ
AU2003235055B2 (en) Human checkpoint kinase, HCDS1, compositions and methods
KR100740342B1 (ko) Pkc 델타의 hspb1 결합부위를 포함하는 암 치료용조성물
US20040151713A1 (en) Cell cycle regulatory factor
US20020102248A1 (en) Modulating response to genotoxic stress
PT1328621E (pt) 13245, uma nova proteína cinase humana de tipo distrofia miotónica e suas utilizações
Williams Characterization of the in vitro protein binding interactions of the extreme C-terminal domains of ataxia telangiectasia mutated and the DNA-dependent protein kinase