ATE304052T1 - Humane checkpointkinase, hcds1, zusammensetzungen und verfahren - Google Patents

Humane checkpointkinase, hcds1, zusammensetzungen und verfahren

Info

Publication number
ATE304052T1
ATE304052T1 AT98966890T AT98966890T ATE304052T1 AT E304052 T1 ATE304052 T1 AT E304052T1 AT 98966890 T AT98966890 T AT 98966890T AT 98966890 T AT98966890 T AT 98966890T AT E304052 T1 ATE304052 T1 AT E304052T1
Authority
AT
Austria
Prior art keywords
hcds1
protein
methods
compositions
checkpoint kinase
Prior art date
Application number
AT98966890T
Other languages
English (en)
Inventor
Walter H M Luyten
Andrew E Parker
Clare Mcgowan
Alessandra Blasina
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of ATE304052T1 publication Critical patent/ATE304052T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Dental Preparations (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT98966890T 1997-10-22 1998-10-21 Humane checkpointkinase, hcds1, zusammensetzungen und verfahren ATE304052T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9722320.0A GB9722320D0 (en) 1997-10-22 1997-10-22 Human cell cycle checkpoint proteins
PCT/EP1998/006981 WO1999025843A2 (en) 1997-10-22 1998-10-21 Human checkpoint kinase, hcds1, compositions and methods

Publications (1)

Publication Number Publication Date
ATE304052T1 true ATE304052T1 (de) 2005-09-15

Family

ID=10820925

Family Applications (2)

Application Number Title Priority Date Filing Date
AT98955533T ATE300619T1 (de) 1997-10-22 1998-10-21 Humane checkpointkinase, hcds1, zusammensetzungen und verfahren
AT98966890T ATE304052T1 (de) 1997-10-22 1998-10-21 Humane checkpointkinase, hcds1, zusammensetzungen und verfahren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT98955533T ATE300619T1 (de) 1997-10-22 1998-10-21 Humane checkpointkinase, hcds1, zusammensetzungen und verfahren

Country Status (13)

Country Link
US (4) US6413755B1 (de)
EP (2) EP1025236B1 (de)
JP (2) JP4261050B2 (de)
AT (2) ATE300619T1 (de)
AU (2) AU760544B2 (de)
CA (2) CA2306492C (de)
DE (2) DE69831500T2 (de)
DK (2) DK1025236T3 (de)
ES (2) ES2245807T3 (de)
GB (1) GB9722320D0 (de)
IL (2) IL135687A (de)
NZ (2) NZ503965A (de)
WO (2) WO1999025843A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins
WO1999067369A1 (en) * 1998-06-23 1999-12-29 Chugai Seiyaku Kabushiki Kaisha Cell cycle regulatory factor
GB9827430D0 (en) * 1998-12-11 1999-02-03 Ludwig Inst Cancer Res Differential expression in primary breast cancer
WO2001061016A2 (en) * 2000-02-18 2001-08-23 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
AU2001237599A1 (en) * 2000-03-08 2001-09-17 Zealand Pharma A/S Materials and methods relating to the degradation of cdc25a in response to dna damage
CA2406399A1 (en) * 2000-04-20 2001-11-01 Incyte Genomics, Inc. Human kinases
US6323016B1 (en) 2000-06-09 2001-11-27 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
FR2812945B1 (fr) * 2000-08-10 2002-10-04 Aventis Pharma Sa Utilisation de la proteine grf1 et cellules exprimant la proteine grf1 pour le criblage de molecules
US6372468B1 (en) * 2000-09-14 2002-04-16 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
AU2002211305A1 (en) * 2000-12-14 2002-06-24 Pe Corporation (Ny) Isolated human kinase proteins, their encoding nucleic acid molecules, and uses thereof
US6451538B1 (en) * 2000-12-22 2002-09-17 Isis Pharmaceuticals, Inc. Antisense modulation of CHK2 expression
WO2002051858A2 (en) * 2000-12-22 2002-07-04 Isis Pharmaceuticals, Inc. Antisense modulation of chk2 expression
AU2002246858A1 (en) 2000-12-27 2002-08-06 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
EP1224942A1 (de) * 2001-01-23 2002-07-24 Bernhard Dr. Nieswandt Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases
DK1585749T3 (da) * 2003-01-09 2008-09-22 Pfizer Diazepinoindol-derivater som kinaseinhibitorer
EP1660504B1 (de) * 2003-08-29 2008-10-29 Pfizer Inc. Als neue antiangiogene mittel geeignete thienopyridinphenylacetamide und derivate davon
BRPI0414011A (pt) * 2003-08-29 2006-10-24 Pfizer naftalencarboxamidas e seus derivados úteis como novos agentes antiangiogênicos
US8572169B2 (en) * 2006-08-28 2013-10-29 Myspace, Llc System, apparatus and method for discovery of music within a social network
EP2409700A1 (de) 2007-05-08 2012-01-25 Schering Corporation Verfahren zur Behandlung mit intravenösen Formulierungen mit Temozolomid
ES2378513T3 (es) * 2008-08-06 2012-04-13 Pfizer Inc. Compuestos 2-heterociclilamino piracinas sustituidas en posición 6 como inhibidores de CHK-1

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443962A (en) * 1993-06-04 1995-08-22 Mitotix, Inc. Methods of identifying inhibitors of cdc25 phosphatase
US5674748A (en) * 1995-03-14 1997-10-07 Thomas Jefferson University Human cyclin-dependent kinase-like proteins and methods of using the same
AU1461197A (en) * 1995-11-16 1997-06-05 Icos Corporation Cell cycle checkpoint pik-related kinase materials and methods
US5744349A (en) * 1996-03-05 1998-04-28 Washington University DNA sequences encoding human Myt1 kinase
US6218109B1 (en) * 1997-09-05 2001-04-17 Baylor College Of Medicine Mammalian checkpoint genes and proteins
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins

Also Published As

Publication number Publication date
US20050180981A1 (en) 2005-08-18
EP1025236B1 (de) 2005-07-27
JP4261050B2 (ja) 2009-04-30
ES2245050T3 (es) 2005-12-16
WO1999025843A3 (en) 1999-08-05
US20030017160A1 (en) 2003-01-23
DE69831500T2 (de) 2006-06-14
EP1025236A2 (de) 2000-08-09
US6943013B2 (en) 2005-09-13
NZ503983A (en) 2002-03-28
DK1025236T3 (da) 2005-10-24
CA2306492A1 (en) 1999-05-27
IL135688A0 (en) 2001-05-20
CA2308013A1 (en) 1999-04-29
CA2306492C (en) 2014-03-25
WO1999020747A3 (en) 1999-07-01
ES2245807T3 (es) 2006-01-16
JP2001523461A (ja) 2001-11-27
IL135687A (en) 2007-07-04
US6413755B1 (en) 2002-07-02
WO1999020747A2 (en) 1999-04-29
AU2612699A (en) 1999-06-07
JP2001520037A (ja) 2001-10-30
AU760544B2 (en) 2003-05-15
IL135687A0 (en) 2001-05-20
DE69831500D1 (de) 2005-10-13
WO1999025843A2 (en) 1999-05-27
ATE300619T1 (de) 2005-08-15
DE69831007D1 (de) 2005-09-01
NZ503965A (en) 2002-03-28
AU752617B2 (en) 2002-09-26
US7414020B2 (en) 2008-08-19
AU1232299A (en) 1999-05-10
EP1025237A2 (de) 2000-08-09
DK1025237T3 (da) 2005-11-28
DE69831007T2 (de) 2006-04-20
GB9722320D0 (en) 1997-12-17
JP4418103B2 (ja) 2010-02-17
US6531312B1 (en) 2003-03-11
EP1025237B1 (de) 2005-09-07
IL135688A (en) 2010-04-29

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