DE69831007D1 - Humane checkpointkinase, hcds1, zusammensetzungen und verfahren - Google Patents

Humane checkpointkinase, hcds1, zusammensetzungen und verfahren

Info

Publication number
DE69831007D1
DE69831007D1 DE69831007T DE69831007T DE69831007D1 DE 69831007 D1 DE69831007 D1 DE 69831007D1 DE 69831007 T DE69831007 T DE 69831007T DE 69831007 T DE69831007 T DE 69831007T DE 69831007 D1 DE69831007 D1 DE 69831007D1
Authority
DE
Germany
Prior art keywords
hcds1
protein
compositions
checkpoint kinase
human checkpoint
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69831007T
Other languages
English (en)
Other versions
DE69831007T2 (de
Inventor
H Luyten
E Parker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of DE69831007D1 publication Critical patent/DE69831007D1/de
Application granted granted Critical
Publication of DE69831007T2 publication Critical patent/DE69831007T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69831007T 1997-10-22 1998-10-21 Humane checkpointkinase, hcds1, zusammensetzungen und verfahren Expired - Lifetime DE69831007T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9722320 1997-10-22
GBGB9722320.0A GB9722320D0 (en) 1997-10-22 1997-10-22 Human cell cycle checkpoint proteins
PCT/EP1998/006982 WO1999020747A2 (en) 1997-10-22 1998-10-21 HUMAN CHECKPOINT KINASE, hCDS1, COMPOSITIONS AND METHODS

Publications (2)

Publication Number Publication Date
DE69831007D1 true DE69831007D1 (de) 2005-09-01
DE69831007T2 DE69831007T2 (de) 2006-04-20

Family

ID=10820925

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69831007T Expired - Lifetime DE69831007T2 (de) 1997-10-22 1998-10-21 Humane checkpointkinase, hcds1, zusammensetzungen und verfahren
DE69831500T Expired - Lifetime DE69831500T2 (de) 1997-10-22 1998-10-21 Humane checkpointkinase, hcds1, zusammensetzungen und verfahren

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69831500T Expired - Lifetime DE69831500T2 (de) 1997-10-22 1998-10-21 Humane checkpointkinase, hcds1, zusammensetzungen und verfahren

Country Status (13)

Country Link
US (4) US6413755B1 (de)
EP (2) EP1025236B1 (de)
JP (2) JP4261050B2 (de)
AT (2) ATE304052T1 (de)
AU (2) AU760544B2 (de)
CA (2) CA2308013A1 (de)
DE (2) DE69831007T2 (de)
DK (2) DK1025237T3 (de)
ES (2) ES2245050T3 (de)
GB (1) GB9722320D0 (de)
IL (2) IL135687A (de)
NZ (2) NZ503965A (de)
WO (2) WO1999025843A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins
CA2331152A1 (en) * 1998-06-23 1999-12-29 Chugai Seiyaku Kabushiki Kaisha Cell cycle regulating factor
GB9827430D0 (en) * 1998-12-11 1999-02-03 Ludwig Inst Cancer Res Differential expression in primary breast cancer
JP2003531577A (ja) * 2000-02-18 2003-10-28 レキシコン・ジェネティクス・インコーポレーテッド 新規ヒトキナーゼおよびそれをコードするポリヌクレオチド
AU2001237599A1 (en) * 2000-03-08 2001-09-17 Zealand Pharma A/S Materials and methods relating to the degradation of cdc25a in response to dna damage
WO2001081555A2 (en) * 2000-04-20 2001-11-01 Incyte Genomics, Inc. Human kinases
US6323016B1 (en) 2000-06-09 2001-11-27 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
FR2812945B1 (fr) * 2000-08-10 2002-10-04 Aventis Pharma Sa Utilisation de la proteine grf1 et cellules exprimant la proteine grf1 pour le criblage de molecules
US6372468B1 (en) * 2000-09-14 2002-04-16 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
AU2002211305A1 (en) * 2000-12-14 2002-06-24 Pe Corporation (Ny) Isolated human kinase proteins, their encoding nucleic acid molecules, and uses thereof
US6451538B1 (en) * 2000-12-22 2002-09-17 Isis Pharmaceuticals, Inc. Antisense modulation of CHK2 expression
WO2002051858A2 (en) * 2000-12-22 2002-07-04 Isis Pharmaceuticals, Inc. Antisense modulation of chk2 expression
AU2002246858A1 (en) 2000-12-27 2002-08-06 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
EP1224942A1 (de) * 2001-01-23 2002-07-24 Bernhard Dr. Nieswandt Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases
AU2004203977B2 (en) * 2003-01-09 2010-06-17 Pfizer Inc. Diazepinoindole derivatives as kinase inhibitors
JP2007504122A (ja) * 2003-08-29 2007-03-01 ファイザー・インク 新規抗血管形成剤として有用なチエノピリジン−フェニルアセトアミドおよびその誘導体
CA2536788A1 (en) * 2003-08-29 2005-03-10 Pfizer Inc. Naphthalene carboxamides and their derivatives useful as new anti-angiogenic agents
US8572169B2 (en) * 2006-08-28 2013-10-29 Myspace, Llc System, apparatus and method for discovery of music within a social network
US20100210700A1 (en) 2007-05-08 2010-08-19 Schering Corporation Methods of treatment using intravenous formulations comprising temozolomide
EP2328890B1 (de) * 2008-08-06 2012-01-25 Pfizer Inc. 6-substituierte 2-heterocyclylaminopyrazinverbindungen als chk-1-inhibitoren

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443962A (en) * 1993-06-04 1995-08-22 Mitotix, Inc. Methods of identifying inhibitors of cdc25 phosphatase
US5674748A (en) * 1995-03-14 1997-10-07 Thomas Jefferson University Human cyclin-dependent kinase-like proteins and methods of using the same
CN1199420A (zh) * 1995-11-16 1998-11-18 艾科斯有限公司 细胞周期关卡与pik相关的激酶材料和方法
US5744349A (en) * 1996-03-05 1998-04-28 Washington University DNA sequences encoding human Myt1 kinase
US6218109B1 (en) * 1997-09-05 2001-04-17 Baylor College Of Medicine Mammalian checkpoint genes and proteins
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins

Also Published As

Publication number Publication date
ES2245050T3 (es) 2005-12-16
EP1025237B1 (de) 2005-09-07
DK1025237T3 (da) 2005-11-28
DK1025236T3 (da) 2005-10-24
DE69831500T2 (de) 2006-06-14
WO1999025843A2 (en) 1999-05-27
JP2001520037A (ja) 2001-10-30
US6413755B1 (en) 2002-07-02
CA2308013A1 (en) 1999-04-29
NZ503965A (en) 2002-03-28
ES2245807T3 (es) 2006-01-16
AU752617B2 (en) 2002-09-26
IL135688A (en) 2010-04-29
EP1025236B1 (de) 2005-07-27
EP1025236A2 (de) 2000-08-09
CA2306492A1 (en) 1999-05-27
US6943013B2 (en) 2005-09-13
AU2612699A (en) 1999-06-07
CA2306492C (en) 2014-03-25
JP4261050B2 (ja) 2009-04-30
US20050180981A1 (en) 2005-08-18
ATE300619T1 (de) 2005-08-15
JP4418103B2 (ja) 2010-02-17
WO1999020747A2 (en) 1999-04-29
AU760544B2 (en) 2003-05-15
AU1232299A (en) 1999-05-10
WO1999025843A3 (en) 1999-08-05
NZ503983A (en) 2002-03-28
IL135687A (en) 2007-07-04
DE69831500D1 (de) 2005-10-13
IL135687A0 (en) 2001-05-20
EP1025237A2 (de) 2000-08-09
US6531312B1 (en) 2003-03-11
IL135688A0 (en) 2001-05-20
ATE304052T1 (de) 2005-09-15
DE69831007T2 (de) 2006-04-20
GB9722320D0 (en) 1997-12-17
US7414020B2 (en) 2008-08-19
JP2001523461A (ja) 2001-11-27
WO1999020747A3 (en) 1999-07-01
US20030017160A1 (en) 2003-01-23

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