AU2001237599A1 - Materials and methods relating to the degradation of cdc25a in response to dna damage - Google Patents

Materials and methods relating to the degradation of cdc25a in response to dna damage

Info

Publication number
AU2001237599A1
AU2001237599A1 AU2001237599A AU3759901A AU2001237599A1 AU 2001237599 A1 AU2001237599 A1 AU 2001237599A1 AU 2001237599 A AU2001237599 A AU 2001237599A AU 3759901 A AU3759901 A AU 3759901A AU 2001237599 A1 AU2001237599 A1 AU 2001237599A1
Authority
AU
Australia
Prior art keywords
cdc25a
degradation
response
materials
dna damage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001237599A
Inventor
Jiri Bartek
Jakob Falck
Claudia Lukas
Jiri Lukas
Randi Syljuasen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zealand Pharma AS
Original Assignee
Zealand Pharma AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0005573A external-priority patent/GB0005573D0/en
Priority claimed from GB0101021A external-priority patent/GB0101021D0/en
Application filed by Zealand Pharma AS filed Critical Zealand Pharma AS
Publication of AU2001237599A1 publication Critical patent/AU2001237599A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03048Protein-tyrosine-phosphatase (3.1.3.48)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2001237599A 2000-03-08 2001-03-08 Materials and methods relating to the degradation of cdc25a in response to dna damage Abandoned AU2001237599A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0005573 2000-03-08
GB0005573A GB0005573D0 (en) 2000-03-08 2000-03-08 Materials and methods relating to the degradation of CDC25A in response to DNA damage
GB0101021A GB0101021D0 (en) 2001-01-15 2001-01-15 Materials and methods relating to the degradation of Cdc25A in response to DNA damage
GB0101021 2001-01-15
PCT/GB2001/001008 WO2001066708A2 (en) 2000-03-08 2001-03-08 MATERIALS AND METHODS RELATING TO THE DEGRADATION OF Cdc25A IN RESPONSE TO DNA DAMAGE

Publications (1)

Publication Number Publication Date
AU2001237599A1 true AU2001237599A1 (en) 2001-09-17

Family

ID=26243813

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001237599A Abandoned AU2001237599A1 (en) 2000-03-08 2001-03-08 Materials and methods relating to the degradation of cdc25a in response to dna damage

Country Status (4)

Country Link
US (1) US20020147145A1 (en)
EP (1) EP1265992A2 (en)
AU (1) AU2001237599A1 (en)
WO (1) WO2001066708A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6797825B2 (en) 2001-12-13 2004-09-28 Abbott Laboratories Protein kinase inhibitors
US20030187026A1 (en) 2001-12-13 2003-10-02 Qun Li Kinase inhibitors
WO2003098220A1 (en) * 2002-05-15 2003-11-27 Zealand Pharma A/S Modulation of mitosis by enhancing the interaction of cdc24a and cyclinb/cdk1
GB0308711D0 (en) * 2003-04-15 2003-05-21 Univ The Glasgow Assay methods
AU2003902066A0 (en) * 2003-05-01 2003-05-15 Norika Holdings Extraction process for a pharmaceutical product
EP2247953A2 (en) * 2008-02-04 2010-11-10 Dana-farber Cancer Institute, Inc. Chk1 suppresses a caspase-2 apoptotic response to dna damage that bypasses p53, bcl-2 and caspase-3
US8778890B2 (en) 2009-03-31 2014-07-15 Temple University—Of the Commonwealth System of Higher Education Leptin antagonist and methods of use
CN107058233A (en) * 2017-05-03 2017-08-18 上海长海医院 A kind of method for reducing tumour cell to the drug resistance of antineoplastic

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2891023B2 (en) * 1993-03-09 1999-05-17 味の素株式会社 Method for producing lanthionine-containing material
US5981201A (en) * 1997-01-08 1999-11-09 Beth Israel Deaconess Medical Center Methods of detection and treatment of breast cancer
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins
US6011058A (en) * 1998-09-22 2000-01-04 Georgia Tech Research Corporation Seco-cholestane derivatives and methods of making the same

Also Published As

Publication number Publication date
US20020147145A1 (en) 2002-10-10
WO2001066708A2 (en) 2001-09-13
WO2001066708A3 (en) 2002-01-03
EP1265992A2 (en) 2002-12-18

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