JP4418103B2 - 新規なヒトチェックポイントキナーゼ、ｈＣＤＳ１、組成物および方法 - Google Patents
新規なヒトチェックポイントキナーゼ、ｈＣＤＳ１、組成物および方法 Download PDFInfo
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- JP4418103B2 JP4418103B2 JP2000517068A JP2000517068A JP4418103B2 JP 4418103 B2 JP4418103 B2 JP 4418103B2 JP 2000517068 A JP2000517068 A JP 2000517068A JP 2000517068 A JP2000517068 A JP 2000517068A JP 4418103 B2 JP4418103 B2 JP 4418103B2
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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| PCT/EP1998/006982 WO1999020747A2 (en) | 1997-10-22 | 1998-10-21 | HUMAN CHECKPOINT KINASE, hCDS1, COMPOSITIONS AND METHODS |
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| CA2331152A1 (en) * | 1998-06-23 | 1999-12-29 | Chugai Seiyaku Kabushiki Kaisha | Cell cycle regulating factor |
| GB9827430D0 (en) * | 1998-12-11 | 1999-02-03 | Ludwig Inst Cancer Res | Differential expression in primary breast cancer |
| CA2400785A1 (en) * | 2000-02-18 | 2001-08-23 | Lexicon Genetics Incorporated | Novel human kinases and polynucleotides encoding the same |
| AU2001237599A1 (en) * | 2000-03-08 | 2001-09-17 | Zealand Pharma A/S | Materials and methods relating to the degradation of cdc25a in response to dna damage |
| CA2406399A1 (en) * | 2000-04-20 | 2001-11-01 | Incyte Genomics, Inc. | Human kinases |
| US6323016B1 (en) | 2000-06-09 | 2001-11-27 | Pe Corporation (Ny) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof |
| FR2812945B1 (fr) * | 2000-08-10 | 2002-10-04 | Aventis Pharma Sa | Utilisation de la proteine grf1 et cellules exprimant la proteine grf1 pour le criblage de molecules |
| US6372468B1 (en) * | 2000-09-14 | 2002-04-16 | Pe Corporation (Ny) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof |
| AU2002211305A1 (en) * | 2000-12-14 | 2002-06-24 | Pe Corporation (Ny) | Isolated human kinase proteins, their encoding nucleic acid molecules, and uses thereof |
| WO2002051858A2 (en) * | 2000-12-22 | 2002-07-04 | Isis Pharmaceuticals, Inc. | Antisense modulation of chk2 expression |
| US6451538B1 (en) * | 2000-12-22 | 2002-09-17 | Isis Pharmaceuticals, Inc. | Antisense modulation of CHK2 expression |
| WO2002059325A2 (en) * | 2000-12-27 | 2002-08-01 | Lexicon Genetics Incorporated | Human kinases and polynucleotides encoding the same |
| EP1224942A1 (en) * | 2001-01-23 | 2002-07-24 | Bernhard Dr. Nieswandt | Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases |
| EP1947102A1 (en) * | 2003-01-09 | 2008-07-23 | Pfizer, Inc. | Compositions comprising diazepinoindole derivatives as kinase inhibitors |
| EP1660503A1 (en) * | 2003-08-29 | 2006-05-31 | Pfizer Inc. | Naphthalene carboxamides and their derivatives useful as new anti-angiogenic agents |
| WO2005021554A1 (en) * | 2003-08-29 | 2005-03-10 | Pfizer Inc. | Thienopyridine-phenylacet amides and their derivatives useful as new anti-angiogenic agents |
| US8572169B2 (en) * | 2006-08-28 | 2013-10-29 | Myspace, Llc | System, apparatus and method for discovery of music within a social network |
| MX2009012054A (es) | 2007-05-08 | 2009-11-19 | Schering Corp | Metodos de tratamiento que usan formulaciones intravenosas que comprenden temozolomida. |
| CA2731368C (en) * | 2008-08-06 | 2013-05-14 | Pfizer Inc. | 6 substituted 2-heterocyclylamino pyrazine compounds as chk-1 inhibitors |
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| US5443962A (en) * | 1993-06-04 | 1995-08-22 | Mitotix, Inc. | Methods of identifying inhibitors of cdc25 phosphatase |
| US5674748A (en) * | 1995-03-14 | 1997-10-07 | Thomas Jefferson University | Human cyclin-dependent kinase-like proteins and methods of using the same |
| PL322876A1 (en) * | 1995-11-16 | 1998-03-02 | Icos Corp | Pik type kinase of cellular cycle control point: materials and methods |
| US5744349A (en) * | 1996-03-05 | 1998-04-28 | Washington University | DNA sequences encoding human Myt1 kinase |
| US6218109B1 (en) * | 1997-09-05 | 2001-04-17 | Baylor College Of Medicine | Mammalian checkpoint genes and proteins |
| GB9722320D0 (en) * | 1997-10-22 | 1997-12-17 | Janssen Pharmaceutica Nv | Human cell cycle checkpoint proteins |
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- 1998-10-21 AU AU26126/99A patent/AU760544B2/en not_active Ceased
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- 1998-10-21 AT AT98966890T patent/ATE304052T1/de not_active IP Right Cessation
- 1998-10-21 US US09/529,093 patent/US6413755B1/en not_active Expired - Lifetime
- 1998-10-21 EP EP98955533A patent/EP1025236B1/en not_active Expired - Lifetime
- 1998-10-21 AU AU12322/99A patent/AU752617B2/en not_active Expired
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2002
- 2002-06-27 US US10/185,182 patent/US6943013B2/en not_active Expired - Lifetime
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