ES2245050T3 - Nueva quinasa humana punto de control, hcds1, composiciones y procedimientos. - Google Patents
Nueva quinasa humana punto de control, hcds1, composiciones y procedimientos.Info
- Publication number
- ES2245050T3 ES2245050T3 ES98955533T ES98955533T ES2245050T3 ES 2245050 T3 ES2245050 T3 ES 2245050T3 ES 98955533 T ES98955533 T ES 98955533T ES 98955533 T ES98955533 T ES 98955533T ES 2245050 T3 ES2245050 T3 ES 2245050T3
- Authority
- ES
- Spain
- Prior art keywords
- nucleic acid
- hcds1
- protein
- present
- dna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 description 1
- 229960004528 vincristine Drugs 0.000 description 1
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 description 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 description 1
- CILBMBUYJCWATM-PYGJLNRPSA-N vinorelbine ditartrate Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O.OC(=O)[C@H](O)[C@@H](O)C(O)=O.C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC CILBMBUYJCWATM-PYGJLNRPSA-N 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Dental Preparations (AREA)
- Medicines Containing Plant Substances (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9722320.0A GB9722320D0 (en) | 1997-10-22 | 1997-10-22 | Human cell cycle checkpoint proteins |
| GB9722320 | 1997-10-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2245050T3 true ES2245050T3 (es) | 2005-12-16 |
Family
ID=10820925
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98966890T Expired - Lifetime ES2245807T3 (es) | 1997-10-22 | 1998-10-21 | Quinasa humana de puntos de control, hcds1, composiciones y procedimientos. |
| ES98955533T Expired - Lifetime ES2245050T3 (es) | 1997-10-22 | 1998-10-21 | Nueva quinasa humana punto de control, hcds1, composiciones y procedimientos. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98966890T Expired - Lifetime ES2245807T3 (es) | 1997-10-22 | 1998-10-21 | Quinasa humana de puntos de control, hcds1, composiciones y procedimientos. |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US6413755B1 (enExample) |
| EP (2) | EP1025236B1 (enExample) |
| JP (2) | JP4418103B2 (enExample) |
| AT (2) | ATE300619T1 (enExample) |
| AU (2) | AU760544B2 (enExample) |
| CA (2) | CA2308013A1 (enExample) |
| DE (2) | DE69831500T2 (enExample) |
| DK (2) | DK1025236T3 (enExample) |
| ES (2) | ES2245807T3 (enExample) |
| GB (1) | GB9722320D0 (enExample) |
| IL (2) | IL135687A (enExample) |
| NZ (2) | NZ503983A (enExample) |
| WO (2) | WO1999025843A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9722320D0 (en) * | 1997-10-22 | 1997-12-17 | Janssen Pharmaceutica Nv | Human cell cycle checkpoint proteins |
| EP1090987A4 (en) * | 1998-06-23 | 2003-05-28 | Chugai Pharmaceutical Co Ltd | CELL CYCLE REGULATION FACTOR |
| GB9827430D0 (en) * | 1998-12-11 | 1999-02-03 | Ludwig Inst Cancer Res | Differential expression in primary breast cancer |
| US20020038011A1 (en) * | 2000-02-18 | 2002-03-28 | Walke D. Wade | Novel human kinases and polynucleotides encoding the same |
| AU2001237599A1 (en) * | 2000-03-08 | 2001-09-17 | Zealand Pharma A/S | Materials and methods relating to the degradation of cdc25a in response to dna damage |
| EP1297150A2 (en) * | 2000-04-20 | 2003-04-02 | Incyte Genomics, Inc. | Human kinases |
| US6323016B1 (en) | 2000-06-09 | 2001-11-27 | Pe Corporation (Ny) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof |
| FR2812945B1 (fr) * | 2000-08-10 | 2002-10-04 | Aventis Pharma Sa | Utilisation de la proteine grf1 et cellules exprimant la proteine grf1 pour le criblage de molecules |
| US6372468B1 (en) * | 2000-09-14 | 2002-04-16 | Pe Corporation (Ny) | Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof |
| WO2002048328A2 (en) * | 2000-12-14 | 2002-06-20 | Pe Corporation (Ny) | Isolated human kinase proteins, their encoding nucleic acid molecules, and uses thereof |
| US6451538B1 (en) * | 2000-12-22 | 2002-09-17 | Isis Pharmaceuticals, Inc. | Antisense modulation of CHK2 expression |
| WO2002051858A2 (en) * | 2000-12-22 | 2002-07-04 | Isis Pharmaceuticals, Inc. | Antisense modulation of chk2 expression |
| WO2002059325A2 (en) * | 2000-12-27 | 2002-08-01 | Lexicon Genetics Incorporated | Human kinases and polynucleotides encoding the same |
| EP1224942A1 (en) * | 2001-01-23 | 2002-07-24 | Bernhard Dr. Nieswandt | Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases |
| KR100697746B1 (ko) | 2003-01-09 | 2007-03-22 | 화이자 인코포레이티드 | 키나제 저해제로서의 디아제피노인돌 유도체 |
| CA2536788A1 (en) * | 2003-08-29 | 2005-03-10 | Pfizer Inc. | Naphthalene carboxamides and their derivatives useful as new anti-angiogenic agents |
| BRPI0413876A (pt) * | 2003-08-29 | 2006-10-24 | Pfizer | tienopiridin-fenilacetamidas e seus derivados úteis como agentes antiangiogênicos |
| US8572169B2 (en) * | 2006-08-28 | 2013-10-29 | Myspace, Llc | System, apparatus and method for discovery of music within a social network |
| BRPI0823416A2 (pt) | 2007-05-08 | 2015-06-16 | Schering Corp | Métodos de tratamento usando formulações intravenosas compreendendo temozolomida. |
| JP5576370B2 (ja) * | 2008-08-06 | 2014-08-20 | ファイザー・インク | Ｃｈｋ−１阻害剤としての６置換２−ヘテロシクリルアミノピラジン化合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5443962A (en) * | 1993-06-04 | 1995-08-22 | Mitotix, Inc. | Methods of identifying inhibitors of cdc25 phosphatase |
| US5674748A (en) * | 1995-03-14 | 1997-10-07 | Thomas Jefferson University | Human cyclin-dependent kinase-like proteins and methods of using the same |
| IL121306A0 (en) * | 1995-11-16 | 1998-01-04 | Icos Corp | Cell cycle checkpoint pik-related kinase materials and methods |
| US5744349A (en) * | 1996-03-05 | 1998-04-28 | Washington University | DNA sequences encoding human Myt1 kinase |
| US6218109B1 (en) * | 1997-09-05 | 2001-04-17 | Baylor College Of Medicine | Mammalian checkpoint genes and proteins |
| GB9722320D0 (en) * | 1997-10-22 | 1997-12-17 | Janssen Pharmaceutica Nv | Human cell cycle checkpoint proteins |
-
1997
- 1997-10-22 GB GBGB9722320.0A patent/GB9722320D0/en not_active Ceased
-
1998
- 1998-10-21 NZ NZ503983A patent/NZ503983A/en not_active IP Right Cessation
- 1998-10-21 CA CA002308013A patent/CA2308013A1/en not_active Abandoned
- 1998-10-21 IL IL135687A patent/IL135687A/en not_active IP Right Cessation
- 1998-10-21 DK DK98955533T patent/DK1025236T3/da active
- 1998-10-21 EP EP98955533A patent/EP1025236B1/en not_active Expired - Lifetime
- 1998-10-21 DE DE69831500T patent/DE69831500T2/de not_active Expired - Lifetime
- 1998-10-21 JP JP2000517068A patent/JP4418103B2/ja not_active Expired - Lifetime
- 1998-10-21 AT AT98955533T patent/ATE300619T1/de not_active IP Right Cessation
- 1998-10-21 US US09/529,093 patent/US6413755B1/en not_active Expired - Lifetime
- 1998-10-21 CA CA2306492A patent/CA2306492C/en not_active Expired - Fee Related
- 1998-10-21 DE DE69831007T patent/DE69831007T2/de not_active Expired - Lifetime
- 1998-10-21 WO PCT/EP1998/006981 patent/WO1999025843A2/en not_active Ceased
- 1998-10-21 AU AU26126/99A patent/AU760544B2/en not_active Ceased
- 1998-10-21 ES ES98966890T patent/ES2245807T3/es not_active Expired - Lifetime
- 1998-10-21 NZ NZ503965A patent/NZ503965A/en not_active IP Right Cessation
- 1998-10-21 WO PCT/EP1998/006982 patent/WO1999020747A2/en not_active Ceased
- 1998-10-21 IL IL135688A patent/IL135688A/en not_active IP Right Cessation
- 1998-10-21 AT AT98966890T patent/ATE304052T1/de not_active IP Right Cessation
- 1998-10-21 AU AU12322/99A patent/AU752617B2/en not_active Expired
- 1998-10-21 US US09/529,154 patent/US6531312B1/en not_active Expired - Lifetime
- 1998-10-21 JP JP2000521208A patent/JP4261050B2/ja not_active Expired - Fee Related
- 1998-10-21 ES ES98955533T patent/ES2245050T3/es not_active Expired - Lifetime
- 1998-10-21 DK DK98966890T patent/DK1025237T3/da active
- 1998-10-21 EP EP98966890A patent/EP1025237B1/en not_active Expired - Lifetime
-
2002
- 2002-06-27 US US10/185,182 patent/US6943013B2/en not_active Expired - Lifetime
-
2005
- 2005-04-12 US US11/103,704 patent/US7414020B2/en not_active Expired - Fee Related
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