IL135688A - HUMAN CHECKPOINT KINASE hCDS1, PROTEINS, ANTIBODIES AND METHODS OF USE - Google Patents

HUMAN CHECKPOINT KINASE hCDS1, PROTEINS, ANTIBODIES AND METHODS OF USE

Info

Publication number
IL135688A
IL135688A IL135688A IL13568898A IL135688A IL 135688 A IL135688 A IL 135688A IL 135688 A IL135688 A IL 135688A IL 13568898 A IL13568898 A IL 13568898A IL 135688 A IL135688 A IL 135688A
Authority
IL
Israel
Prior art keywords
protein
cell
acid sequence
seq
amino acid
Prior art date
Application number
IL135688A
Other languages
English (en)
Other versions
IL135688A0 (en
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of IL135688A0 publication Critical patent/IL135688A0/xx
Publication of IL135688A publication Critical patent/IL135688A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Dental Preparations (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
IL135688A 1997-10-22 1998-10-21 HUMAN CHECKPOINT KINASE hCDS1, PROTEINS, ANTIBODIES AND METHODS OF USE IL135688A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9722320.0A GB9722320D0 (en) 1997-10-22 1997-10-22 Human cell cycle checkpoint proteins
PCT/EP1998/006981 WO1999025843A2 (en) 1997-10-22 1998-10-21 Human checkpoint kinase, hcds1, compositions and methods

Publications (2)

Publication Number Publication Date
IL135688A0 IL135688A0 (en) 2001-05-20
IL135688A true IL135688A (en) 2010-04-29

Family

ID=10820925

Family Applications (2)

Application Number Title Priority Date Filing Date
IL135688A IL135688A (en) 1997-10-22 1998-10-21 HUMAN CHECKPOINT KINASE hCDS1, PROTEINS, ANTIBODIES AND METHODS OF USE
IL135687A IL135687A (en) 1997-10-22 1998-10-21 Compounds and methods for the modern human kinetic control point HCDS1

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL135687A IL135687A (en) 1997-10-22 1998-10-21 Compounds and methods for the modern human kinetic control point HCDS1

Country Status (13)

Country Link
US (4) US6531312B1 (enExample)
EP (2) EP1025237B1 (enExample)
JP (2) JP4418103B2 (enExample)
AT (2) ATE300619T1 (enExample)
AU (2) AU760544B2 (enExample)
CA (2) CA2306492C (enExample)
DE (2) DE69831500T2 (enExample)
DK (2) DK1025236T3 (enExample)
ES (2) ES2245050T3 (enExample)
GB (1) GB9722320D0 (enExample)
IL (2) IL135688A (enExample)
NZ (2) NZ503983A (enExample)
WO (2) WO1999020747A2 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins
AU4289599A (en) * 1998-06-23 2000-01-10 Chugai Seiyaku Kabushiki Kaisha Cell cycle regulatory factor
GB9827430D0 (en) * 1998-12-11 1999-02-03 Ludwig Inst Cancer Res Differential expression in primary breast cancer
US20020038011A1 (en) * 2000-02-18 2002-03-28 Walke D. Wade Novel human kinases and polynucleotides encoding the same
WO2001066708A2 (en) * 2000-03-08 2001-09-13 Zealand Pharma A/S MATERIALS AND METHODS RELATING TO THE DEGRADATION OF Cdc25A IN RESPONSE TO DNA DAMAGE
AU2001255573A1 (en) * 2000-04-20 2001-11-07 Incyte Genomics, Inc. Human kinases
US6323016B1 (en) 2000-06-09 2001-11-27 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
FR2812945B1 (fr) * 2000-08-10 2002-10-04 Aventis Pharma Sa Utilisation de la proteine grf1 et cellules exprimant la proteine grf1 pour le criblage de molecules
US6372468B1 (en) 2000-09-14 2002-04-16 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
AU2002211305A1 (en) * 2000-12-14 2002-06-24 Pe Corporation (Ny) Isolated human kinase proteins, their encoding nucleic acid molecules, and uses thereof
WO2002051858A2 (en) * 2000-12-22 2002-07-04 Isis Pharmaceuticals, Inc. Antisense modulation of chk2 expression
US6451538B1 (en) 2000-12-22 2002-09-17 Isis Pharmaceuticals, Inc. Antisense modulation of CHK2 expression
WO2002059325A2 (en) * 2000-12-27 2002-08-01 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
EP1224942A1 (en) * 2001-01-23 2002-07-24 Bernhard Dr. Nieswandt Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases
EA009337B1 (ru) * 2003-01-09 2007-12-28 Пфайзер Инк. Трициклические соединения, представляющие собой ингибиторы протеинкиназ, для увеличения эффективности противоопухолевых агентов и лучевой терапии
WO2005021554A1 (en) * 2003-08-29 2005-03-10 Pfizer Inc. Thienopyridine-phenylacet amides and their derivatives useful as new anti-angiogenic agents
EP1660503A1 (en) * 2003-08-29 2006-05-31 Pfizer Inc. Naphthalene carboxamides and their derivatives useful as new anti-angiogenic agents
US8572169B2 (en) * 2006-08-28 2013-10-29 Myspace, Llc System, apparatus and method for discovery of music within a social network
CA2686848A1 (en) 2007-05-08 2008-11-20 Schering Corporation Methods of treatment using intravenous formulations comprising temozolomide
JP5576370B2 (ja) * 2008-08-06 2014-08-20 ファイザー・インク Chk−1阻害剤としての6置換2−ヘテロシクリルアミノピラジン化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5443962A (en) * 1993-06-04 1995-08-22 Mitotix, Inc. Methods of identifying inhibitors of cdc25 phosphatase
US5674748A (en) * 1995-03-14 1997-10-07 Thomas Jefferson University Human cyclin-dependent kinase-like proteins and methods of using the same
IL121306A0 (en) * 1995-11-16 1998-01-04 Icos Corp Cell cycle checkpoint pik-related kinase materials and methods
US5744349A (en) * 1996-03-05 1998-04-28 Washington University DNA sequences encoding human Myt1 kinase
US6218109B1 (en) * 1997-09-05 2001-04-17 Baylor College Of Medicine Mammalian checkpoint genes and proteins
GB9722320D0 (en) * 1997-10-22 1997-12-17 Janssen Pharmaceutica Nv Human cell cycle checkpoint proteins

Also Published As

Publication number Publication date
WO1999025843A2 (en) 1999-05-27
ATE304052T1 (de) 2005-09-15
IL135687A0 (en) 2001-05-20
DK1025236T3 (da) 2005-10-24
US7414020B2 (en) 2008-08-19
CA2306492A1 (en) 1999-05-27
US20030017160A1 (en) 2003-01-23
JP2001523461A (ja) 2001-11-27
WO1999020747A3 (en) 1999-07-01
AU1232299A (en) 1999-05-10
AU752617B2 (en) 2002-09-26
JP4418103B2 (ja) 2010-02-17
DE69831500D1 (de) 2005-10-13
AU2612699A (en) 1999-06-07
ES2245050T3 (es) 2005-12-16
US6531312B1 (en) 2003-03-11
AU760544B2 (en) 2003-05-15
DK1025237T3 (da) 2005-11-28
US6413755B1 (en) 2002-07-02
US20050180981A1 (en) 2005-08-18
EP1025237B1 (en) 2005-09-07
ES2245807T3 (es) 2006-01-16
NZ503983A (en) 2002-03-28
IL135688A0 (en) 2001-05-20
IL135687A (en) 2007-07-04
JP4261050B2 (ja) 2009-04-30
DE69831007T2 (de) 2006-04-20
DE69831500T2 (de) 2006-06-14
CA2308013A1 (en) 1999-04-29
CA2306492C (en) 2014-03-25
JP2001520037A (ja) 2001-10-30
EP1025237A2 (en) 2000-08-09
EP1025236B1 (en) 2005-07-27
NZ503965A (en) 2002-03-28
WO1999025843A3 (en) 1999-08-05
ATE300619T1 (de) 2005-08-15
US6943013B2 (en) 2005-09-13
EP1025236A2 (en) 2000-08-09
GB9722320D0 (en) 1997-12-17
WO1999020747A2 (en) 1999-04-29
DE69831007D1 (de) 2005-09-01

Similar Documents

Publication Publication Date Title
CA2306492C (en) Human checkpoint kinase, hcds1, compositions and methods
US6656716B1 (en) Polypeptide fragments of human PAK5 protein kinase
US5698428A (en) Human PAK65
JP3091769B2 (ja) プロテインキナーゼ
JP2008115164A (ja) IκBキナーゼ、そのサブユニット、およびこれらを使用する方法
US6689575B2 (en) IκB kinase, subunits thereof, and methods of using same
US6190663B1 (en) Human MAP kinase homolog
US6586242B1 (en) TAO protein kinases and methods of use therefor
US5830699A (en) SOK-1 and methods of use
US6383791B1 (en) Molecules of the HKID-1-related protein family and uses thereof
JP2001517430A (ja) ヒトSte20様ストレス活性化セリン/スレオニンキナーゼ
AU2003235055B2 (en) Human checkpoint kinase, HCDS1, compositions and methods
US20050037446A1 (en) Agents that recognize src when phosphorylated at serine 17
WO1999067369A1 (en) Cell cycle regulatory factor

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired