ES2240180T3 - Administracion sub-tenon de medicamentos. - Google Patents
Administracion sub-tenon de medicamentos.Info
- Publication number
- ES2240180T3 ES2240180T3 ES00968673T ES00968673T ES2240180T3 ES 2240180 T3 ES2240180 T3 ES 2240180T3 ES 00968673 T ES00968673 T ES 00968673T ES 00968673 T ES00968673 T ES 00968673T ES 2240180 T3 ES2240180 T3 ES 2240180T3
- Authority
- ES
- Spain
- Prior art keywords
- cannula
- distal part
- distal
- tenon
- tip
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 208000005590 Choroidal Neovascularization Diseases 0.000 description 10
- 206010060823 Choroidal neovascularisation Diseases 0.000 description 10
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- 241001631457 Cannula Species 0.000 description 7
- 210000000795 conjunctiva Anatomy 0.000 description 7
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- 239000013583 drug formulation Substances 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
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- 201000010230 macular retinal edema Diseases 0.000 description 3
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- 239000000243 solution Substances 0.000 description 3
- 239000004037 angiogenesis inhibitor Substances 0.000 description 2
- 230000001772 anti-angiogenic effect Effects 0.000 description 2
- 230000001384 anti-glaucoma Effects 0.000 description 2
- 239000002260 anti-inflammatory agent Substances 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 230000000340 anti-metabolite Effects 0.000 description 2
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- 230000004438 eyesight Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
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- 230000006785 proliferative vitreoretinopathy Effects 0.000 description 2
- 230000003637 steroidlike Effects 0.000 description 2
- 230000000699 topical effect Effects 0.000 description 2
- GGUSQTSTQSHJAH-UHFFFAOYSA-N 1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol Chemical compound C=1C=C(Cl)C=CC=1C(O)CN(CC1)CCC1CC1=CC=C(F)C=C1 GGUSQTSTQSHJAH-UHFFFAOYSA-N 0.000 description 1
- 102000003846 Carbonic anhydrases Human genes 0.000 description 1
- 108090000209 Carbonic anhydrases Proteins 0.000 description 1
- 208000002691 Choroiditis Diseases 0.000 description 1
- 206010058202 Cystoid macular oedema Diseases 0.000 description 1
- 206010012689 Diabetic retinopathy Diseases 0.000 description 1
- 208000031969 Eye Hemorrhage Diseases 0.000 description 1
- 208000001860 Eye Infections Diseases 0.000 description 1
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 208000003971 Posterior uveitis Diseases 0.000 description 1
- 208000002158 Proliferative Vitreoretinopathy Diseases 0.000 description 1
- 206010038934 Retinopathy proliferative Diseases 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 208000036866 Vitreoretinopathy Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000001800 adrenalinergic effect Effects 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000002160 alpha blocker Substances 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 238000001949 anaesthesia Methods 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000002924 anti-infective effect Effects 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 229960005475 antiinfective agent Drugs 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 229940121357 antivirals Drugs 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
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- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000000544 cholinesterase inhibitor Substances 0.000 description 1
- 210000003287 ciliary artery Anatomy 0.000 description 1
- 230000001886 ciliary effect Effects 0.000 description 1
- 229960003143 combination antiinfectives Drugs 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000013270 controlled release Methods 0.000 description 1
- 210000004087 cornea Anatomy 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 201000010206 cystoid macular edema Diseases 0.000 description 1
- 239000000850 decongestant Substances 0.000 description 1
- 229940124581 decongestants Drugs 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 230000010339 dilation Effects 0.000 description 1
- 238000009429 electrical wiring Methods 0.000 description 1
- 229950005455 eliprodil Drugs 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 208000011323 eye infectious disease Diseases 0.000 description 1
- 210000004709 eyebrow Anatomy 0.000 description 1
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- 239000003527 fibrinolytic agent Substances 0.000 description 1
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- 210000003630 histaminocyte Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000003589 local anesthetic agent Substances 0.000 description 1
- 208000018769 loss of vision Diseases 0.000 description 1
- 231100000864 loss of vision Toxicity 0.000 description 1
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- 208000021971 neovascular inflammatory vitreoretinopathy Diseases 0.000 description 1
- 230000001067 neuroprotector Effects 0.000 description 1
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- 238000011587 new zealand white rabbit Methods 0.000 description 1
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- 229910000811 surgical stainless steel Inorganic materials 0.000 description 1
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- 238000007910 systemic administration Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Prostheses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16166099P | 1999-10-21 | 1999-10-21 | |
| US161660P | 1999-10-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2240180T3 true ES2240180T3 (es) | 2005-10-16 |
Family
ID=22582174
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES00968673T Expired - Lifetime ES2240180T3 (es) | 1999-10-21 | 2000-10-04 | Administracion sub-tenon de medicamentos. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6413245B1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP1522289A3 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2003511204A (cg-RX-API-DMAC7.html) |
| AR (4) | AR026075A1 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE290837T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU775149B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR0014930B1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2383572C (cg-RX-API-DMAC7.html) |
| DE (1) | DE60018777T2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2240180T3 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1049438B (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA02002376A (cg-RX-API-DMAC7.html) |
| PT (1) | PT1221918E (cg-RX-API-DMAC7.html) |
| TW (1) | TW467740B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2001028473A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (186)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6936053B1 (en) * | 1998-07-02 | 2005-08-30 | Jeffrey N. Weiss | Ocular implant needle |
| SI1173124T1 (en) * | 1999-04-26 | 2005-08-31 | Gmp Vision Solutions Inc | Shunt device and method for treating glaucoma |
| US7943162B2 (en) * | 1999-10-21 | 2011-05-17 | Alcon, Inc. | Drug delivery device |
| EP1175879A1 (en) * | 2000-02-02 | 2002-01-30 | Ooo Meditsinsky Nauchno-Issledovatelsky Oftalmolog Ichesky Tsentr "Novy Vzglyad" | Kourenkov's cannula used for a method for an operation of refractory-correlating eximer-laser intrastromal keratectomy (reik) |
| US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
| ES2271301T3 (es) * | 2001-07-23 | 2007-04-16 | Alcon, Inc. | Dispositivo de suministro de farmaco oftalmico. |
| CN1203814C (zh) | 2001-07-23 | 2005-06-01 | 爱尔康公司 | 眼部药物输送装置 |
| JP4892800B2 (ja) * | 2001-08-24 | 2012-03-07 | 株式会社ジェイ・エム・エス | 薬液注入用針管、および該薬液注入用針管を装着した注射器 |
| US7153316B1 (en) | 2001-11-09 | 2006-12-26 | Mcdonald Marguerite B | Surgical instruments and method for corneal reformation |
| US6802829B2 (en) * | 2001-11-16 | 2004-10-12 | Infinite Vision, Llc | Spray device |
| CN1658894A (zh) * | 2002-02-14 | 2005-08-24 | 默克专利股份有限公司 | 用于治疗眼病的方法和组合物 |
| JP2004041492A (ja) * | 2002-07-12 | 2004-02-12 | Scitec Kk | 医療用針 |
| DE10238310A1 (de) * | 2002-08-21 | 2004-03-04 | Erich Jaeger Gmbh | Elektrodenanordnung |
| WO2004026347A2 (en) * | 2002-09-17 | 2004-04-01 | Iscience Surgical Corporation | Apparatus and method for surgical bypass of aqueous humor |
| WO2004028477A2 (en) * | 2002-09-29 | 2004-04-08 | Surmodics, Inc. | Methods for treatment and/or prevention of retinal disease |
| US7141048B1 (en) * | 2002-10-17 | 2006-11-28 | Alcon, Inc. | Vitreoretinal instrument |
| US7285107B1 (en) | 2002-10-17 | 2007-10-23 | Alcon, Inc. | Vitreoretinal instrument |
| CA2516782A1 (en) * | 2003-02-20 | 2004-09-02 | Alcon, Inc. | Use of steroids to treat ocular disorders |
| CN100431544C (zh) * | 2003-02-20 | 2008-11-12 | 爱尔康公司 | 用于治疗病理性眼血管生成的糖皮质激素制剂 |
| US20040199130A1 (en) * | 2003-04-03 | 2004-10-07 | Chornenky Victor I. | Apparatus and method for treatment of macular degeneration |
| US20070043006A1 (en) * | 2003-06-13 | 2007-02-22 | Bingaman David P | Formulations of non-steroidal anti-inflammatory agents to treat pathologic ocular angiogenesis |
| CA2528718A1 (en) * | 2003-06-20 | 2004-12-29 | Alcon, Inc. | Treatment of amd with combination of ingredients |
| EP1684669A4 (en) * | 2003-07-10 | 2008-01-02 | Alcon Inc | DEVICE FOR RELEASING AN OPHTHALMIC MEDICINAL PRODUCT |
| DE10337863A1 (de) | 2003-08-18 | 2005-03-17 | Merck Patent Gmbh | Verwendung von Chromen-4-on-Derivaten |
| KR101160702B1 (ko) * | 2003-08-20 | 2012-06-28 | 산텐 세이야꾸 가부시키가이샤 | 미립자 테논낭하 투여 약물 전달 시스템 |
| JP4869930B2 (ja) * | 2003-08-26 | 2012-02-08 | ヴィスタ サイエンティフィック エルエルシー | 眼科薬物供給装置 |
| CN102144961A (zh) | 2003-09-18 | 2011-08-10 | 参天制药株式会社 | 经巩膜递送 |
| WO2005048873A2 (en) * | 2003-11-12 | 2005-06-02 | Alcon, Inc. | Kit for administration of a drug |
| US20090148527A1 (en) * | 2007-12-07 | 2009-06-11 | Robinson Michael R | Intraocular formulation |
| EP1740239A4 (en) * | 2004-04-29 | 2008-12-03 | Iscience Interventional Corp | DEVICE AND METHOD FOR THE SURGICAL REINFORCEMENT OF THE DRAINAGE OF AQUEOUS HUMOR |
| US20080058704A1 (en) * | 2004-04-29 | 2008-03-06 | Michael Hee | Apparatus and Method for Ocular Treatment |
| WO2006002366A2 (en) * | 2004-06-24 | 2006-01-05 | Surmodics, Inc. | Biodegradable ocular devices, methods and systems |
| WO2006014484A2 (en) | 2004-07-02 | 2006-02-09 | Surmodics, Inc. | Methods and devices for the treatment of ocular conditions |
| US20060047250A1 (en) * | 2004-08-30 | 2006-03-02 | Hickingbotham Dyson W | Fluid delivery device |
| US7402156B2 (en) | 2004-09-01 | 2008-07-22 | Alcon, Inc. | Counter pressure device for ophthalmic drug delivery |
| US7226435B2 (en) * | 2004-10-14 | 2007-06-05 | Alcon, Inc. | Drug delivery device |
| MX2007006735A (es) * | 2004-12-22 | 2007-07-25 | Alcon Inc | Dispositivo para entregar farmaco oftalmico. |
| CN104147005B (zh) | 2005-02-09 | 2018-07-03 | 参天制药株式会社 | 用于治疗疾病或病症的液体制剂 |
| US8663639B2 (en) | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
| JP2006257080A (ja) * | 2005-02-18 | 2006-09-28 | Santen Pharmaceut Co Ltd | ステロイド化合物の副作用軽減または回避方法 |
| KR20070104645A (ko) * | 2005-02-18 | 2007-10-26 | 산텐 세이야꾸 가부시키가이샤 | 스테로이드 화합물의 부작용 경감 또는 회피 방법 |
| WO2006094014A2 (en) | 2005-02-28 | 2006-09-08 | The Regents Of The University Of California | Methods for diagnosis and treatment of endometrial cancer |
| EP1868661A1 (en) * | 2005-04-08 | 2007-12-26 | SurModics, Inc. | Sustained release implants for subretinal delivery |
| US8318906B2 (en) | 2005-04-15 | 2012-11-27 | The Regents Of The University Of California | EMP2 antibodies and their therapeutic uses |
| US20070038174A1 (en) * | 2005-08-09 | 2007-02-15 | Hopkins Mark A | Ophthalmic injector system |
| US20070060887A1 (en) * | 2005-08-22 | 2007-03-15 | Marsh David A | Ophthalmic injector |
| US20070134244A1 (en) * | 2005-10-14 | 2007-06-14 | Alcon, Inc. | Combination treatment for pathologic ocular angiogenesis |
| JP5063358B2 (ja) * | 2005-10-31 | 2012-10-31 | テルモ株式会社 | 穿刺器具、投与器具及び穿刺方法 |
| US20070156096A1 (en) * | 2005-11-10 | 2007-07-05 | Terumo Kabushiki Kaisha | Puncture device |
| US7611492B2 (en) * | 2005-11-10 | 2009-11-03 | Terumo Kabushiki Kaisha | Puncture device |
| BRPI0620249A2 (pt) * | 2005-12-22 | 2011-11-08 | Alcon Res Ltd | inibidores de c3-convertase para prevenção e tratamento de degeneração macular correlacionada à idade em pacientes com riscos alternativos do fator h de complemento |
| JP5528708B2 (ja) | 2006-02-09 | 2014-06-25 | 参天製薬株式会社 | 安定な製剤ならびにそれらを調製および使用する方法 |
| US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
| JP5506378B2 (ja) | 2006-03-23 | 2014-05-28 | 参天製薬株式会社 | 血管透過性に関連する疾患または病気のための製剤および方法 |
| US8197435B2 (en) * | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
| US20210393436A1 (en) * | 2006-05-02 | 2021-12-23 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
| US7674243B2 (en) * | 2006-05-17 | 2010-03-09 | Alcon Inc. | Ophthalmic injection device using piezoelectric array |
| US7862540B2 (en) * | 2006-05-17 | 2011-01-04 | Alcon Research, Ltd. | Ophthalmic injection device using shape memory alloy |
| US7887521B2 (en) * | 2006-05-17 | 2011-02-15 | Alcon Research, Ltd. | Ophthalmic injection system |
| US20070270744A1 (en) * | 2006-05-17 | 2007-11-22 | Bruno Dacquay | Limited Reuse Assembly For Ophthalmic Injection Device |
| US20070270750A1 (en) * | 2006-05-17 | 2007-11-22 | Alcon, Inc. | Drug delivery device |
| US7811252B2 (en) * | 2006-05-17 | 2010-10-12 | Alcon Research, Ltd. | Dosage control device |
| US20070270768A1 (en) * | 2006-05-17 | 2007-11-22 | Bruno Dacquay | Mechanical Linkage Mechanism For Ophthalmic Injection Device |
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2000
- 2000-10-04 DE DE60018777T patent/DE60018777T2/de not_active Expired - Lifetime
- 2000-10-04 WO PCT/US2000/027367 patent/WO2001028473A1/en not_active Ceased
- 2000-10-04 PT PT00968673T patent/PT1221918E/pt unknown
- 2000-10-04 JP JP2001531070A patent/JP2003511204A/ja active Pending
- 2000-10-04 ES ES00968673T patent/ES2240180T3/es not_active Expired - Lifetime
- 2000-10-04 US US09/677,656 patent/US6413245B1/en not_active Expired - Lifetime
- 2000-10-04 BR BRPI0014930-6A patent/BR0014930B1/pt not_active IP Right Cessation
- 2000-10-04 EP EP05100176A patent/EP1522289A3/en not_active Withdrawn
- 2000-10-04 HK HK03100463.5A patent/HK1049438B/en not_active IP Right Cessation
- 2000-10-04 EP EP00968673A patent/EP1221918B1/en not_active Expired - Lifetime
- 2000-10-04 MX MXPA02002376A patent/MXPA02002376A/es active IP Right Grant
- 2000-10-04 CA CA002383572A patent/CA2383572C/en not_active Expired - Fee Related
- 2000-10-04 AT AT00968673T patent/ATE290837T1/de active
- 2000-10-04 AU AU78548/00A patent/AU775149B2/en not_active Ceased
- 2000-10-18 AR ARP000105478A patent/AR026075A1/es active IP Right Grant
- 2000-10-20 TW TW089122136A patent/TW467740B/zh not_active IP Right Cessation
-
2003
- 2003-03-25 AR ARP030101036A patent/AR039133A2/es active IP Right Grant
- 2003-03-25 AR ARP030101031A patent/AR036065A2/es unknown
- 2003-03-25 AR ARP030101032A patent/AR036066A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60018777T2 (de) | 2006-02-02 |
| CA2383572C (en) | 2007-12-11 |
| BR0014930B1 (pt) | 2009-01-13 |
| EP1221918B1 (en) | 2005-03-16 |
| AU7854800A (en) | 2001-04-30 |
| AR039133A2 (es) | 2005-02-09 |
| HK1049438A1 (en) | 2003-05-16 |
| AU775149B2 (en) | 2004-07-22 |
| EP1522289A3 (en) | 2008-01-23 |
| EP1522289A2 (en) | 2005-04-13 |
| MXPA02002376A (es) | 2002-08-28 |
| AR036066A2 (es) | 2004-08-11 |
| DE60018777D1 (de) | 2005-04-21 |
| US6413245B1 (en) | 2002-07-02 |
| HK1049438B (en) | 2005-08-26 |
| JP2003511204A (ja) | 2003-03-25 |
| ATE290837T1 (de) | 2005-04-15 |
| CA2383572A1 (en) | 2001-04-26 |
| TW467740B (en) | 2001-12-11 |
| WO2001028473A1 (en) | 2001-04-26 |
| AR026075A1 (es) | 2002-12-26 |
| AR036065A2 (es) | 2004-08-11 |
| PT1221918E (pt) | 2005-06-30 |
| BR0014930A (pt) | 2003-07-15 |
| EP1221918A1 (en) | 2002-07-17 |
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