ES2194782T3 - Procedimiento mejorado de deteccion de bacterias acidorresistentes del genero helicobacter en las heces. - Google Patents

Procedimiento mejorado de deteccion de bacterias acidorresistentes del genero helicobacter en las heces.

Info

Publication number
ES2194782T3
ES2194782T3 ES00967861T ES00967861T ES2194782T3 ES 2194782 T3 ES2194782 T3 ES 2194782T3 ES 00967861 T ES00967861 T ES 00967861T ES 00967861 T ES00967861 T ES 00967861T ES 2194782 T3 ES2194782 T3 ES 2194782T3
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ES
Spain
Prior art keywords
antigen
acid
mammal
receptor
detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00967861T
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English (en)
Other versions
ES2194782T5 (es
Inventor
Christian Reiter
Gerhard Cullmann
Petra Heppner
Achim Ringeis
Heidemarie Muller
Eva Haindl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Connex Gesellschaft zur Optimierung von Forschung und Entwicklung mbH
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Connex Gesellschaft zur Optimierung von Forschung und Entwicklung mbH
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Application filed by Connex Gesellschaft zur Optimierung von Forschung und Entwicklung mbH filed Critical Connex Gesellschaft zur Optimierung von Forschung und Entwicklung mbH
Application granted granted Critical
Publication of ES2194782T3 publication Critical patent/ES2194782T3/es
Publication of ES2194782T5 publication Critical patent/ES2194782T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/121—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Helicobacter (Campylobacter) (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56922—Campylobacter
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/908—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96486—Metalloendopeptidases (3.4.24)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • G01N2333/98—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Procedimiento para la detección de una infección de una bacteria acidorresistente del género Helicobacter en un mamífero, en el que (a) se incuba una muestra de excrementos del mamífero empleando (aa) un receptor en condiciones que permitan la formación de un complejo de un antígeno de la bacteria acidorresistente con el receptor; o (ab) se incuban dos receptores distintos en condiciones que permitan la formación de un complejo de un antígeno de la bacteria acidorresistente con los dos receptores y en el que el receptor según (aa) o los receptores según (ab) se une(n) específicamente a un antígeno que, por lo menos en una parte del mamífero después de haber pasado el tracto intestinal, presenta una estructura que corresponde a la estructura nativa o a la estructura frente a la cual un mamífero produce o genera anticuerpos después de una infección o inmunización con la bacteria acidorresistente o con un extracto o con un lisado de la misma o con un fragmento de la misma o con un péptido sintético; y (b) se detecta la formación de un complejo de antígeno- receptor según (a).
ES00967861.6T 1999-10-12 2000-10-12 Procedimiento mejorado de detección de bacterias acidorresistentes del género Helicobacter en las heces Expired - Lifetime ES2194782T5 (es)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP99120351 1999-10-12
EP99120351 1999-10-12
EP00105592 2000-03-16
EP00105592 2000-03-16
EP00107028 2000-03-31
EP00107028 2000-03-31
EP00110110 2000-05-10
EP00110110 2000-05-10
PCT/EP2000/010058 WO2001027613A2 (de) 1999-10-12 2000-10-12 Verbessertes verfahren zum nachweis von säure-resistenten mikroorganismen im stuhl

Publications (2)

Publication Number Publication Date
ES2194782T3 true ES2194782T3 (es) 2003-12-01
ES2194782T5 ES2194782T5 (es) 2014-08-20

Family

ID=27439941

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00967861.6T Expired - Lifetime ES2194782T5 (es) 1999-10-12 2000-10-12 Procedimiento mejorado de detección de bacterias acidorresistentes del género Helicobacter en las heces

Country Status (16)

Country Link
US (1) US7129053B1 (es)
EP (2) EP1336850A1 (es)
JP (2) JP2003511697A (es)
CN (1) CN1382259A (es)
AT (1) ATE236398T1 (es)
AU (2) AU1137301A (es)
BR (1) BR0014734A (es)
CA (1) CA2387473C (es)
DE (1) DE50001665D1 (es)
DK (1) DK1232392T3 (es)
ES (1) ES2194782T5 (es)
IL (1) IL149062A0 (es)
PT (1) PT1232392E (es)
SI (1) SI1232392T1 (es)
TR (1) TR200201006T2 (es)
WO (2) WO2001027613A2 (es)

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PT1232392E (pt) 2003-08-29
WO2001027612A2 (de) 2001-04-19
BR0014734A (pt) 2002-06-18
EP1232392B2 (de) 2014-04-02
IL149062A0 (en) 2002-11-10
CA2387473C (en) 2010-02-02
US7129053B1 (en) 2006-10-31
ES2194782T5 (es) 2014-08-20
SI1232392T1 (en) 2003-10-31
CA2387473A1 (en) 2001-04-19
AU7787100A (en) 2001-04-23
CN1382259A (zh) 2002-11-27
JP2003511698A (ja) 2003-03-25
DK1232392T3 (da) 2003-07-28
WO2001027612A3 (de) 2001-10-11
AU1137301A (en) 2001-04-23
EP1232392B1 (de) 2003-04-02
WO2001027613A3 (de) 2001-10-18
ATE236398T1 (de) 2003-04-15
EP1336850A1 (de) 2003-08-20
EP1232392A1 (de) 2002-08-21
JP2003511697A (ja) 2003-03-25
WO2001027613A2 (de) 2001-04-19
DE50001665D1 (de) 2003-05-08

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