ES2160803T3 - Composicion farmaceutica de aplicacion topica, su procedimiento de produccion y su utilizacion. - Google Patents

Composicion farmaceutica de aplicacion topica, su procedimiento de produccion y su utilizacion.

Info

Publication number
ES2160803T3
ES2160803T3 ES96905579T ES96905579T ES2160803T3 ES 2160803 T3 ES2160803 T3 ES 2160803T3 ES 96905579 T ES96905579 T ES 96905579T ES 96905579 T ES96905579 T ES 96905579T ES 2160803 T3 ES2160803 T3 ES 2160803T3
Authority
ES
Spain
Prior art keywords
composition
active substance
liquid
dissolved
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96905579T
Other languages
English (en)
Inventor
Volker Eisenreich
Gerhard Hantich
Ernst Hesse
Torsten Moller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GEBRO PHARMA GmbH
Original Assignee
GEBRO PHARMA GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GEBRO PHARMA GmbH filed Critical GEBRO PHARMA GmbH
Application granted granted Critical
Publication of ES2160803T3 publication Critical patent/ES2160803T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

SE DESCRIBE UNA COMPOSICION FARMACEUTICA APLICABLE POR VIA TOPICA QUE CONTIENE AL MENOS UN LIPIDO LIQUIDO, UNA SUSTANCIA ACTIVA FARMACEUTICA COMO MINIMO, QUE PUEDE DISOLVERSE EN AL MENOS UNO DE LOS LIPIDOS LIQUIDOS Y ES ABSORBIDA POR LA PIEL, Y UN GEL HIDRATADO QUE SUPONE EL COMPONENTE PRINCIPAL DE LA COMPOSICION; UN LIPIDO Y UNA SUSTANCIA ACTIVA COMO MINIMO ESTAN INCORPORADOS AL GEL Y LA COMPOSICION ESTA ESENCIALMENTE LIBRE DE EMULSIONANTES Y COMPONENTES SOLIDOS, A EXCEPCION DEL GELATINIZANTE NECESARIO PARA LA FORMACION DEL GEL HIDRATADO. TODAS LAS SUSTANCIAS ACTIVAS ESTAN EN FORMA DISUELTA, PERO AL MENOS UNA SUSTANCIA ACTIVA ESTA DISUELTA EN EL LIPIDO LIQUIDO, Y ESTE LIPIDO QUE CONTIENE LA SUSTANCIA ACTIVA DISUELTA ESTA INCORPORADO COMO TAL COMO FASE INTERNA EN EL GEL HIDRATADO QUE FORMA LA FASE EXTERNA. BASICAMENTE LA COMPOSICION ESTA LIBRE DE SUSTANCIAS SURFACTIVAS. EL PROCEDIMIENTO PARA LA FABRICACION DE ESTA COMPOSICION FARMACEUTICA, APLICABLE POR VIA TOPICA, PREVE QUE AL MENOS UNA SUSTANCIA ACTIVA ABSORBIBLE POR LA PIEL SE DISUELVA EN UN LIPIDO, PREFERENTEMENTE EN FORMA CONCENTRADA, Y QUE LUEGO ESTA SOLUCION SE INCORPORE COMO FASE INTERNA EN UN HIDROGEL QUE FORMA LA FASE EXTERNA, FORMANDO ESTE HIDROGEL EL COMPONENTE PRINCIPAL DE LA COMPOSICION. LA COMPOSICION ASI OBTENIDA ES ALTAMENTE ESTABLE Y TIENE BUENAS PROPIEDADES GALENICAS.
ES96905579T 1995-03-17 1996-03-14 Composicion farmaceutica de aplicacion topica, su procedimiento de produccion y su utilizacion. Expired - Lifetime ES2160803T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0047595A AT408067B (de) 1995-03-17 1995-03-17 Pharmazeutische zusammensetzung zur topischen applizierung und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ES2160803T3 true ES2160803T3 (es) 2001-11-16

Family

ID=3491605

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96905579T Expired - Lifetime ES2160803T3 (es) 1995-03-17 1996-03-14 Composicion farmaceutica de aplicacion topica, su procedimiento de produccion y su utilizacion.

Country Status (20)

Country Link
US (1) US5894019A (es)
EP (1) EP0814776B1 (es)
JP (1) JPH11502809A (es)
KR (1) KR100253027B1 (es)
AT (2) AT408067B (es)
AU (1) AU697767B2 (es)
BR (1) BR9607668A (es)
CA (1) CA2211006C (es)
CZ (1) CZ291211B6 (es)
DE (2) DE29680194U1 (es)
DK (1) DK0814776T3 (es)
ES (1) ES2160803T3 (es)
GR (1) GR3036772T3 (es)
HU (1) HU222047B1 (es)
NO (1) NO315685B1 (es)
NZ (1) NZ303085A (es)
PL (1) PL186445B1 (es)
PT (1) PT814776E (es)
SK (1) SK282261B6 (es)
WO (1) WO1996029056A1 (es)

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Also Published As

Publication number Publication date
DE29680194U1 (de) 1998-03-19
KR100253027B1 (ko) 2000-05-01
NO315685B1 (no) 2003-10-13
HUP9801175A3 (en) 2000-06-28
PL186445B1 (pl) 2004-01-30
CA2211006C (en) 2001-08-07
US5894019A (en) 1999-04-13
AU4930796A (en) 1996-10-08
GR3036772T3 (en) 2002-01-31
CA2211006A1 (en) 1996-09-26
ATA47595A (de) 2001-01-15
EP0814776A1 (de) 1998-01-07
PT814776E (pt) 2001-12-28
SK99797A3 (en) 1998-01-14
KR19980702929A (ko) 1998-09-05
SK282261B6 (sk) 2001-12-03
HU222047B1 (hu) 2003-04-28
ATE202698T1 (de) 2001-07-15
CZ291211B6 (cs) 2003-01-15
NZ303085A (en) 1998-11-25
DE59607224D1 (de) 2001-08-09
AT408067B (de) 2001-08-27
JPH11502809A (ja) 1999-03-09
EP0814776B1 (de) 2001-07-04
CZ284097A3 (en) 1997-11-12
AU697767B2 (en) 1998-10-15
WO1996029056A1 (de) 1996-09-26
PL322267A1 (en) 1998-01-19
NO974023L (no) 1997-09-02
BR9607668A (pt) 1998-06-16
HUP9801175A2 (hu) 1998-08-28
DK0814776T3 (da) 2001-10-22
NO974023D0 (no) 1997-09-02

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