ES2175419T3 - Preparacion farmaceutica que contiene nimesulida para uso topico. - Google Patents
Preparacion farmaceutica que contiene nimesulida para uso topico.Info
- Publication number
- ES2175419T3 ES2175419T3 ES97927313T ES97927313T ES2175419T3 ES 2175419 T3 ES2175419 T3 ES 2175419T3 ES 97927313 T ES97927313 T ES 97927313T ES 97927313 T ES97927313 T ES 97927313T ES 2175419 T3 ES2175419 T3 ES 2175419T3
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical preparation
- nimesulide
- topical use
- preparation containing
- containing nimesulide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- HYWYRSMBCFDLJT-UHFFFAOYSA-N nimesulide Chemical compound CS(=O)(=O)NC1=CC=C([N+]([O-])=O)C=C1OC1=CC=CC=C1 HYWYRSMBCFDLJT-UHFFFAOYSA-N 0.000 title abstract 3
- 229960000965 nimesulide Drugs 0.000 title abstract 3
- 230000000699 topical effect Effects 0.000 title abstract 3
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PREPARADO FARMACEUTICO PARA USO TOPICO QUE CONTIENE COMO PRINCIPIO ACTIVO NIMESULIDE (CAS NO 51 803 - 78 - 2) O UNO DE SUS DERIVADOS ACTIVOS. LA PRESENTE INVENCION SE CARACTERIZA PORQUE LA BASE DE DICHO PREPARADO CONTIENE AL MENOS UN FOSFOLIPIDO Y AL MENOS UNA SUSTANCIA DE REACCION ACIDA, Y ESPECIFICAMENTE UN ACIDO. LA FIGURA MUESTRA LOS RESULTADOS DE UNA PRUEBA DE ABSORCION DE NIMESULIDE EX VIVO EFECTUADA CON AYUDA DE FORMULACIONES PARA APLICACION TOPICA INCLUYENDO LAS QUE CONSTITUYEN EL OBJETO DE LA PRESENTE INVENCION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT96RM000480A IT1291278B1 (it) | 1996-07-05 | 1996-07-05 | Preparazione farmaceutica a base di nimesulide per uso topico |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2175419T3 true ES2175419T3 (es) | 2002-11-16 |
Family
ID=11404325
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97927313T Expired - Lifetime ES2175419T3 (es) | 1996-07-05 | 1997-07-02 | Preparacion farmaceutica que contiene nimesulida para uso topico. |
Country Status (13)
Country | Link |
---|---|
US (1) | US5998480A (es) |
EP (1) | EP0853476B1 (es) |
JP (1) | JPH11512116A (es) |
KR (1) | KR19990044280A (es) |
CN (1) | CN1199335A (es) |
AT (1) | ATE215367T1 (es) |
CA (1) | CA2231118C (es) |
DE (1) | DE69711588T2 (es) |
DK (1) | DK0853476T5 (es) |
ES (1) | ES2175419T3 (es) |
IT (1) | IT1291278B1 (es) |
PT (1) | PT853476E (es) |
WO (1) | WO1998001124A2 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1289973B1 (it) * | 1997-02-25 | 1998-10-19 | Helsinn Healthcare Sa | Sistemi gelificati di nimesulide per uso topico |
IT1291895B1 (it) | 1997-04-24 | 1999-01-21 | Errekappa Euroterapici S P A | Preparazione farmaceutica fluida a base di nimesulide per uso orale e rinofaringeo |
AU1888900A (en) * | 1999-05-31 | 2000-12-18 | Shashikant Prabhudas Kurani | A novel formulation of n-(4-nitro-2-phenoxyphenyl)methanesulfonamide |
EP1172101A1 (en) * | 2000-06-20 | 2002-01-16 | Helsinn Healthcare S.A. | The use of nimesulide for the treatment of psoriasis and psoriatic arthritis |
IT1318588B1 (it) * | 2000-06-20 | 2003-08-27 | Helsinn Healthcare Sa | Uso della nimesulide nel trattamento di patologie dermatologiche. |
KR100752990B1 (ko) * | 2006-08-02 | 2007-08-30 | 주식회사 대웅 | 나노리포좀 및 천연 추출물을 포함하는 피부 질환의 예방또는 치료용 조성물 |
TR200906775A1 (tr) * | 2009-09-02 | 2011-03-21 | Sanovel İlaç San.Ve Ti̇c.A.Ş. | Nimesulid ve kas gevşetici kombinasyonları |
WO2014125085A1 (en) | 2013-02-15 | 2014-08-21 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Oral pharmaceutical formulations comprising nimesulide and thiocolchicoside |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR206496A1 (es) * | 1972-07-03 | 1976-07-30 | Riker Laboratories Inc | Procedimiento para la preparacion de 2-fenoxi-4-nitro-alquil o haloalquilsulfonanilidas |
US4933172A (en) * | 1988-10-06 | 1990-06-12 | Warner-Lambert Co. | Method of and compositions for treating destructive periodontal disease |
WO1991000043A1 (en) * | 1989-06-28 | 1991-01-10 | Black & Decker Inc. | Toaster |
ES2023552A6 (es) * | 1990-05-22 | 1992-01-16 | Leetrim Limited | Procedimiento para la preparacion de compuestos de inclusion de nimesulida con ciclodextrina. |
IT1251838B (it) * | 1991-09-20 | 1995-05-26 | Lpb Ist Farm | Uso della nimesulide nel trattamento della cataratta |
IL106035A0 (en) * | 1992-06-24 | 1993-10-20 | Skyview Cooling Co | Pest eradicating composition and methods for reducing pests on growing plants utilizing the same |
US5830499A (en) * | 1994-09-27 | 1998-11-03 | Rijksuniversiteit Leiden | Phospholipid-and cholestrol-free aqueous composition for topical application to the skin |
BR9509183A (pt) * | 1994-10-05 | 1997-12-30 | Helsinn Healthcare Sa | Agente antiinflamatório para uso externo |
US5763422A (en) * | 1995-01-27 | 1998-06-09 | Board Of Regents, The University Of Texas System | Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein |
US5654337A (en) * | 1995-03-24 | 1997-08-05 | II William Scott Snyder | Topical formulation for local delivery of a pharmaceutically active agent |
HUP9601442A3 (en) * | 1995-07-25 | 1999-03-29 | Panacea Biotec Ltd | Nes antinflammatory and analgetic pharmaceutical compositions, containing nimesulid for transdermal use, and process for producing them |
US5814659A (en) * | 1996-04-23 | 1998-09-29 | Dtr Dermal Therapy (Barbados) Inc. | Topical analgesic composition |
HUP9601443A3 (en) * | 1996-05-29 | 1999-03-29 | Panacea Biotec Ltd | Injectable analgetic pharmaceutical compositions for intramuscular use containing nimesulid, and process for producing them |
US5837289A (en) * | 1996-07-23 | 1998-11-17 | Grasela; John C. | Transdermal delivery of medications using a combination of penetration enhancers |
IT1286496B1 (it) * | 1996-11-20 | 1998-07-15 | Leetrim Ltd Dublin | Composizione farmaceutica orale ad attivita' antipiretica,analgesica ed antiinfiammatoria |
-
1996
- 1996-07-05 IT IT96RM000480A patent/IT1291278B1/it active IP Right Grant
-
1997
- 1997-07-02 KR KR1019980701516A patent/KR19990044280A/ko not_active Application Discontinuation
- 1997-07-02 CA CA002231118A patent/CA2231118C/en not_active Expired - Fee Related
- 1997-07-02 AT AT97927313T patent/ATE215367T1/de not_active IP Right Cessation
- 1997-07-02 ES ES97927313T patent/ES2175419T3/es not_active Expired - Lifetime
- 1997-07-02 US US09/029,456 patent/US5998480A/en not_active Expired - Lifetime
- 1997-07-02 DE DE69711588T patent/DE69711588T2/de not_active Expired - Fee Related
- 1997-07-02 PT PT97927313T patent/PT853476E/pt unknown
- 1997-07-02 JP JP10504989A patent/JPH11512116A/ja not_active Ceased
- 1997-07-02 CN CN97191123A patent/CN1199335A/zh active Pending
- 1997-07-02 EP EP97927313A patent/EP0853476B1/en not_active Expired - Lifetime
- 1997-07-02 DK DK97927313T patent/DK0853476T5/da active
- 1997-07-02 WO PCT/IB1997/000816 patent/WO1998001124A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US5998480A (en) | 1999-12-07 |
ITRM960480A1 (it) | 1998-01-05 |
PT853476E (pt) | 2002-08-30 |
DE69711588D1 (de) | 2002-05-08 |
CA2231118A1 (en) | 1998-01-15 |
DK0853476T3 (da) | 2002-07-29 |
IT1291278B1 (it) | 1999-01-07 |
JPH11512116A (ja) | 1999-10-19 |
CN1199335A (zh) | 1998-11-18 |
DK0853476T5 (da) | 2002-10-07 |
EP0853476B1 (en) | 2002-04-03 |
WO1998001124A2 (en) | 1998-01-15 |
WO1998001124A3 (en) | 1998-02-19 |
ATE215367T1 (de) | 2002-04-15 |
EP0853476A2 (en) | 1998-07-22 |
KR19990044280A (ko) | 1999-06-25 |
DE69711588T2 (de) | 2002-10-31 |
ITRM960480A0 (es) | 1996-07-05 |
CA2231118C (en) | 2001-09-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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