ES2148317T3 - Imidazo-piridinas y su utilizacion en enfermedades gastrointestinales. - Google Patents

Imidazo-piridinas y su utilizacion en enfermedades gastrointestinales.

Info

Publication number
ES2148317T3
ES2148317T3 ES94906909T ES94906909T ES2148317T3 ES 2148317 T3 ES2148317 T3 ES 2148317T3 ES 94906909 T ES94906909 T ES 94906909T ES 94906909 T ES94906909 T ES 94906909T ES 2148317 T3 ES2148317 T3 ES 2148317T3
Authority
ES
Spain
Prior art keywords
piridinas
imidazo
gastrointestinal diseases
compounds
ischesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94906909T
Other languages
English (en)
Spanish (es)
Inventor
Jorg Senn-Bilfinger
Gerhard Grundler
Georg Rainer
Stefan Postius
Richard Riedel
Wolfgang-Alexander Simon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Application granted granted Critical
Publication of ES2148317T3 publication Critical patent/ES2148317T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES94906909T 1993-02-15 1994-02-07 Imidazo-piridinas y su utilizacion en enfermedades gastrointestinales. Expired - Lifetime ES2148317T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH45393 1993-02-15
CH194593 1993-06-29

Publications (1)

Publication Number Publication Date
ES2148317T3 true ES2148317T3 (es) 2000-10-16

Family

ID=25684624

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94906909T Expired - Lifetime ES2148317T3 (es) 1993-02-15 1994-02-07 Imidazo-piridinas y su utilizacion en enfermedades gastrointestinales.

Country Status (29)

Country Link
US (1) US5665730A (en, 2012)
EP (1) EP0683780B1 (en, 2012)
JP (1) JP3447292B2 (en, 2012)
KR (1) KR100297057B1 (en, 2012)
CN (1) CN1052005C (en, 2012)
AT (1) ATE192151T1 (en, 2012)
AU (1) AU678434B2 (en, 2012)
BG (1) BG62773B1 (en, 2012)
CA (1) CA2156078C (en, 2012)
CZ (1) CZ287313B6 (en, 2012)
DE (1) DE59409312D1 (en, 2012)
DK (1) DK0683780T3 (en, 2012)
ES (1) ES2148317T3 (en, 2012)
FI (1) FI109537B (en, 2012)
GR (1) GR3033846T3 (en, 2012)
HU (1) HU219395B (en, 2012)
IL (1) IL108520A (en, 2012)
MY (1) MY111201A (en, 2012)
NO (1) NO304889B1 (en, 2012)
NZ (1) NZ261579A (en, 2012)
PL (1) PL175932B1 (en, 2012)
PT (1) PT683780E (en, 2012)
RO (1) RO117917B1 (en, 2012)
RU (1) RU2136682C1 (en, 2012)
SG (1) SG55184A1 (en, 2012)
SK (1) SK280822B6 (en, 2012)
TW (1) TW293008B (en, 2012)
UA (1) UA43841C2 (en, 2012)
WO (1) WO1994018199A1 (en, 2012)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2191979A1 (en) * 1994-06-20 1995-12-28 Muneo Takatani Condensed imidazole compounds, their production and use
FI970330L (fi) * 1994-07-28 1997-01-27 Byk Gulden Lomberg Chem Fab Imidatsopyridiini-atsolidinonit
EP0773944A1 (de) * 1994-07-28 1997-05-21 Byk Gulden Lomberg Chemische Fabrik GmbH Benzylimidazopyridine
AU3343295A (en) * 1994-08-12 1996-03-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Imidazopyridine salt
US6132768A (en) * 1995-07-05 2000-10-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for reversible proton pump inhibitors
JP2949474B2 (ja) * 1995-08-28 1999-09-13 隆久 古田 ペプシノーゲンｉ／ｉｉ比の変化率を基礎としたヘリコバクター・ピロリ除菌判定方法
WO1997027192A1 (de) * 1996-01-26 1997-07-31 Byk Gulden Lomberg Chemische Fabrik Gmbh 3-methylimidazopyridine
AU1545297A (en) * 1996-01-26 1997-08-20 Byk Gulden Imidazopyridine halides
DE19602855A1 (de) * 1996-01-26 1997-07-31 Byk Gulden Lomberg Chem Fab Neue 3-Methylimidazopyridine
US6197783B1 (en) * 1997-03-24 2001-03-06 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyrido compounds
HUP0001555A3 (en) * 1997-10-30 2001-01-29 Altana Pharma Ag Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
SE9802794D0 (sv) 1998-08-21 1998-08-21 Astra Ab New compounds
US6852739B1 (en) * 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
DK1173439T3 (da) * 1999-04-17 2003-09-08 Altana Pharma Ag Halogenalkoxy-imidazonaphthyridiner
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6369087B1 (en) * 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
DE10019714A1 (de) * 2000-04-20 2002-01-10 Gruenenthal Gmbh Salze von bicyclischen, N-acylierten Imidazo-3-aminen und Imidazo-5-aminen
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
UA80393C2 (uk) * 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
DE10145457A1 (de) * 2001-09-14 2003-04-03 Basf Ag Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
AU2003254282A1 (en) * 2002-08-01 2004-02-23 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
AR043063A1 (es) * 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
WO2004080967A1 (en) 2003-03-10 2004-09-23 Altana Pharma Ag Novel process for the preparation of roflumilast
RU2241710C1 (ru) * 2003-04-24 2004-12-10 Ярославский государственный технический университет Способ получения замещенных пиридо[1,2-а][1,3]бензимидазолов
US20080280944A1 (en) 2003-11-03 2008-11-13 Paula Fernstrom Imidazo[1,2-A]Pyridine Derivatives For The Treatment Of Silent Gastro-Esophageal Reflux
AR049168A1 (es) * 2004-05-18 2006-07-05 Altana Pharma Ag Derivados de benzimidazol
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
EP0204785A1 (de) * 1984-12-14 1986-12-17 Ulrich Möbius Halterung für skier
EP0228006A1 (en) * 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
US4831041A (en) * 1986-11-26 1989-05-16 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
GB8722488D0 (en) * 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound

Also Published As

Publication number Publication date
MY111201A (en) 1999-09-30
TW293008B (en, 2012) 1996-12-11
EP0683780A1 (de) 1995-11-29
PT683780E (pt) 2000-10-31
CN1119863A (zh) 1996-04-03
HU219395B (hu) 2001-04-28
UA43841C2 (uk) 2002-01-15
WO1994018199A1 (de) 1994-08-18
FI109537B (fi) 2002-08-30
CA2156078C (en) 2005-02-01
PL175932B1 (pl) 1999-03-31
SK99795A3 (en) 1995-12-06
KR960701051A (ko) 1996-02-24
CN1052005C (zh) 2000-05-03
BG99855A (bg) 1996-04-30
CA2156078A1 (en) 1994-08-18
BG62773B1 (bg) 2000-07-31
CZ287313B6 (en) 2000-10-11
HUT72436A (en) 1996-04-29
FI953838L (fi) 1995-09-06
NO953187L (no) 1995-08-14
NO953187D0 (no) 1995-08-14
RU2136682C1 (ru) 1999-09-10
GR3033846T3 (en) 2000-10-31
IL108520A0 (en) 1994-05-30
JPH08506333A (ja) 1996-07-09
PL310171A1 (en) 1995-11-27
ATE192151T1 (de) 2000-05-15
DK0683780T3 (da) 2000-09-25
NZ261579A (en) 1997-03-24
EP0683780B1 (de) 2000-04-26
CZ208895A3 (en) 1995-12-13
IL108520A (en) 1997-09-30
SG55184A1 (en) 1998-12-21
FI953838A0 (fi) 1995-08-14
RO117917B1 (ro) 2002-09-30
JP3447292B2 (ja) 2003-09-16
SK280822B6 (sk) 2000-08-14
AU678434B2 (en) 1997-05-29
US5665730A (en) 1997-09-09
DE59409312D1 (de) 2000-05-31
KR100297057B1 (ko) 2001-10-24
AU6039194A (en) 1994-08-29
NO304889B1 (no) 1999-03-01

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