ES2130081A1 - Comprimido de maleato de trimebutina con recubrimiento laminar. - Google Patents

Comprimido de maleato de trimebutina con recubrimiento laminar.

Info

Publication number
ES2130081A1
ES2130081A1 ES09701642A ES9701642A ES2130081A1 ES 2130081 A1 ES2130081 A1 ES 2130081A1 ES 09701642 A ES09701642 A ES 09701642A ES 9701642 A ES9701642 A ES 9701642A ES 2130081 A1 ES2130081 A1 ES 2130081A1
Authority
ES
Spain
Prior art keywords
trimebutine maleate
core
coated
maleate tablet
tablet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09701642A
Other languages
English (en)
Other versions
ES2130081B1 (es
Inventor
Loutfy Benkerrour
Bernard Doat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JOUVENINAL LABORATOIRES
Original Assignee
JOUVENINAL LABORATOIRES
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9494890&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2130081(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by JOUVENINAL LABORATOIRES filed Critical JOUVENINAL LABORATOIRES
Publication of ES2130081A1 publication Critical patent/ES2130081A1/es
Application granted granted Critical
Publication of ES2130081B1 publication Critical patent/ES2130081B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Comprimido de maleato de trimebutina con recubrimiento laminar. Comprimido dotado de recubrimiento laminar de maleato de trimebutina destinado a la administración por vía oral, caracterizado por comprender: - un núcleo que comprende de 30 a 60 % de maleato de trimebutina, y excipientes adaptados a la preparación de dicho núcleo siendo éstos apropiados a la estabilidad y a la liberación del principio activo, - un recubrimiento laminar hidrosoluble, de eficacia transitoria pero suficiente para preservar de la desintegración al núcleo y de la liberación prematura del principio activo en el medio bucal.
ES009701642A 1996-08-07 1997-07-24 Comprimido de maleato de trimebutina con recubrimiento laminar. Expired - Fee Related ES2130081B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9609956A FR2752162B1 (fr) 1996-08-07 1996-08-07 Comprime de maleate de trimebutine pellicule

Publications (2)

Publication Number Publication Date
ES2130081A1 true ES2130081A1 (es) 1999-06-16
ES2130081B1 ES2130081B1 (es) 2000-01-01

Family

ID=9494890

Family Applications (2)

Application Number Title Priority Date Filing Date
ES97933713T Expired - Lifetime ES2244002T3 (es) 1996-08-07 1997-07-11 Comprimido de maleato de trimebutina revestido de pelicula.
ES009701642A Expired - Fee Related ES2130081B1 (es) 1996-08-07 1997-07-24 Comprimido de maleato de trimebutina con recubrimiento laminar.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES97933713T Expired - Lifetime ES2244002T3 (es) 1996-08-07 1997-07-11 Comprimido de maleato de trimebutina revestido de pelicula.

Country Status (27)

Country Link
EP (1) EP0942718B1 (es)
JP (1) JP2000515535A (es)
KR (1) KR100539642B1 (es)
CN (1) CN1206986C (es)
AR (1) AR008820A1 (es)
AT (1) ATE300297T1 (es)
AU (1) AU3697097A (es)
BR (1) BR9711032B1 (es)
CA (1) CA2256751C (es)
CO (1) CO4900042A1 (es)
CZ (1) CZ294195B6 (es)
DZ (1) DZ2272A1 (es)
EA (1) EA001506B1 (es)
ES (2) ES2244002T3 (es)
FR (1) FR2752162B1 (es)
GR (1) GR1002907B (es)
HK (1) HK1020888A1 (es)
HU (1) HU228040B1 (es)
IT (1) IT1294671B1 (es)
MX (2) MXPA98010007A (es)
OA (1) OA10968A (es)
PL (1) PL188839B1 (es)
PT (2) PT942718E (es)
TN (1) TNSN97134A1 (es)
TR (1) TR199900261T2 (es)
UA (1) UA52682C2 (es)
WO (1) WO1998005320A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20001302A1 (es) 1998-11-27 2000-11-30 Hoffmann La Roche Preparaciones de una combinacion farmaceutica que contiene carvedilol e hidroclorotiazida
FR2834889B1 (fr) 2002-01-18 2004-04-02 Roquette Freres Forme pharmaceutique solide orodispersible
US20030181488A1 (en) 2002-03-07 2003-09-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof
US7125563B2 (en) * 2002-04-12 2006-10-24 Dava Pharmaceuticals, Inc. Sustained release pharmaceutical preparations and methods for producing the same
EP1726621A1 (en) * 2005-05-26 2006-11-29 Cytec Surface Specialties, S.A. Thermosetting powder compositions
CN100393311C (zh) * 2006-01-26 2008-06-11 孙伟丰 马来酸曲美布汀分散片
CN1927185B (zh) * 2006-10-19 2010-05-19 开开援生制药股份有限公司 具速释部分的马来酸曲美布汀缓释片及其制备工艺
PE20110591A1 (es) 2008-07-28 2011-09-15 Takeda Pharmaceutical Composicion farmaceutica estabilizada a base de un compuesto no peptidico
KR101048487B1 (ko) * 2008-08-19 2011-07-11 한국콜마 주식회사 말레인산트리메부틴 서방정
KR101220829B1 (ko) * 2010-07-16 2013-01-10 안국약품 주식회사 트리메부틴 함유 서방성 정제
CN102462657A (zh) * 2010-11-15 2012-05-23 杭州赛利药物研究所有限公司 马来酸曲美布汀栓剂及其制备方法
WO2014148520A1 (ja) * 2013-03-21 2014-09-25 大正製薬株式会社 固形製剤
RU2536254C1 (ru) * 2013-11-26 2014-12-20 Общество С Ограниченной Ответственностью "Валента-Интеллект" Таблетки-ретард с тримебутином
CN107205984B (zh) * 2015-01-26 2019-11-12 第一三共株式会社 吡咯甲酰胺的固体组合物
RU2706166C2 (ru) * 2017-11-20 2019-11-14 Общество С Ограниченной Ответственностью "Валента - Интеллект" Новые полиморфные формы тримебутина малеата, способ получения и применения
RU2770300C2 (ru) * 2019-10-17 2022-04-15 Общество С Ограниченной Ответственностью "Валента - Интеллект" Новые полиморфные формы тримебутина малеата, способ получения и применения
RU2770301C2 (ru) * 2019-10-17 2022-04-15 Общество С Ограниченной Ответственностью "Валента - Интеллект" Новые полиморфные формы тримебутина малеата, способ получения и применения
CN113171353B (zh) * 2021-04-25 2022-10-21 海南普利制药股份有限公司 一种马来酸曲美布汀片

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2506613A1 (fr) * 1981-05-29 1982-12-03 Tanabe Seiyaku Co Microcapsules d'ethylcellulose
EP0076515A1 (en) * 1981-10-05 1983-04-13 Tanabe Seiyaku Co., Ltd. Rapidly releasable microcapsules and method for the preparation thereof
EP0099109A1 (en) * 1982-07-16 1984-01-25 Tanabe Seiyaku Co., Ltd. Process for preparing free-flowing ethylcellulose microcapsules
ES2019024A6 (es) * 1988-12-28 1991-05-16 Jouveinal Sa Procedimiento de preparar una composicion farmaceutica a base de trimebutina.
JPH03275622A (ja) * 1990-03-26 1991-12-06 Teisan Seiyaku Kk マレイン酸トリメブチンを含有する経口固形製剤
JPH0840885A (ja) * 1994-08-04 1996-02-13 Tanabe Seiyaku Co Ltd 苦味隠蔽されたマレイン酸トリメブチン含有製剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045845B2 (ja) * 1979-10-31 1985-10-12 田辺製薬株式会社 医薬物質含有マイクロカプセルの製法
JPS5858146A (ja) * 1981-10-05 1983-04-06 Tanabe Seiyaku Co Ltd 速放性マイクロカプセル

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2506613A1 (fr) * 1981-05-29 1982-12-03 Tanabe Seiyaku Co Microcapsules d'ethylcellulose
EP0076515A1 (en) * 1981-10-05 1983-04-13 Tanabe Seiyaku Co., Ltd. Rapidly releasable microcapsules and method for the preparation thereof
EP0099109A1 (en) * 1982-07-16 1984-01-25 Tanabe Seiyaku Co., Ltd. Process for preparing free-flowing ethylcellulose microcapsules
ES2019024A6 (es) * 1988-12-28 1991-05-16 Jouveinal Sa Procedimiento de preparar una composicion farmaceutica a base de trimebutina.
JPH03275622A (ja) * 1990-03-26 1991-12-06 Teisan Seiyaku Kk マレイン酸トリメブチンを含有する経口固形製剤
JPH0840885A (ja) * 1994-08-04 1996-02-13 Tanabe Seiyaku Co Ltd 苦味隠蔽されたマレイン酸トリメブチン含有製剤

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BASE DE DATOS WPI en EPOQUE, semana 9204, Londres: Derwent Publications Ltd., AN 92-028855, & JP 3275622 A (TEISAN SEIYAKU KK) 06.12.1991 *
BASE DE DATOS WPI en EPOQUE, semana 9616, Londres: Derwent Publications Ltd., AN 96-157001, & JP 8040885 A (TANABE SEIYAKU CO) 13.02.1996 *

Also Published As

Publication number Publication date
BR9711032B1 (pt) 2008-11-18
CO4900042A1 (es) 2000-03-27
ES2130081B1 (es) 2000-01-01
ES2244002T3 (es) 2005-12-01
UA52682C2 (uk) 2003-01-15
ITGE970067A1 (it) 1999-02-06
CN1206986C (zh) 2005-06-22
CZ294195B6 (cs) 2004-10-13
HK1020888A1 (en) 2000-05-26
OA10968A (fr) 2001-10-30
PT942718E (pt) 2005-10-31
PL331517A1 (en) 1999-07-19
HUP9902878A3 (en) 2000-11-28
TNSN97134A1 (fr) 2005-03-15
PT102031A (pt) 1998-02-27
CN1226162A (zh) 1999-08-18
EA199900102A1 (ru) 1999-06-24
CA2256751C (en) 2008-09-23
WO1998005320A1 (fr) 1998-02-12
EP0942718B1 (fr) 2005-07-27
PT102031B (pt) 2004-07-30
AU3697097A (en) 1998-02-25
DZ2272A1 (fr) 2004-06-20
KR20000029866A (ko) 2000-05-25
ATE300297T1 (de) 2005-08-15
KR100539642B1 (ko) 2005-12-29
CZ37699A3 (cs) 1999-05-12
EA001506B1 (ru) 2001-04-23
MXPA98010007A (es) 2002-07-22
PL188839B1 (pl) 2005-05-31
IT1294671B1 (it) 1999-04-12
EP0942718A1 (fr) 1999-09-22
HU228040B1 (en) 2012-09-28
FR2752162A1 (fr) 1998-02-13
GR1002907B (el) 1998-05-13
CA2256751A1 (fr) 1998-02-12
JP2000515535A (ja) 2000-11-21
MX9706053A (es) 1998-02-28
FR2752162B1 (fr) 1998-11-06
HUP9902878A2 (hu) 2000-04-28
AR008820A1 (es) 2000-02-23
BR9711032A (pt) 1999-08-17
TR199900261T2 (xx) 1999-04-21

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