ES2113074T3 - Recipiente para aerosol con gas propulsor exento de cfc y valvula dosificadora asi como su empleo. - Google Patents

Recipiente para aerosol con gas propulsor exento de cfc y valvula dosificadora asi como su empleo.

Info

Publication number
ES2113074T3
ES2113074T3 ES94810478T ES94810478T ES2113074T3 ES 2113074 T3 ES2113074 T3 ES 2113074T3 ES 94810478 T ES94810478 T ES 94810478T ES 94810478 T ES94810478 T ES 94810478T ES 2113074 T3 ES2113074 T3 ES 2113074T3
Authority
ES
Spain
Prior art keywords
container
cfc
well
aerosol
dispensing valve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94810478T
Other languages
English (en)
Inventor
Francois Brugger
Angelika Dr Stampf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8215022&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2113074(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy AG, Novartis AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2113074T3 publication Critical patent/ES2113074T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/44Valves specially adapted therefor; Regulating devices
    • B65D83/52Valves specially adapted therefor; Regulating devices for metering
    • B65D83/54Metering valves ; Metering valve assemblies

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Otolaryngology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Nozzles (AREA)
  • Details Of Rigid Or Semi-Rigid Containers (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA INVENCION SE REFIERE A UN RECIPIENTE AEROSOL PARA LA APLICACION DE AEROSOL ACTIVO FARMACEUTICAMENTE EN CANTIDADES PREVIAMENTE DETERMINADAS, QUE SE ENCUENTRA PREPARADO EN FORMA DE UNA SUSPENSION EN EL RECIPIENTE, CON LO CUAL LA SUSPENSION A PARTE DE LA SUSTANCIA ACTIVA FARMACEUTICA ABARCA AUN AL MENOS UN GAS DE IMPULSION. EL RECIPIENTE (1) ESTA EQUIPADO CON UNA VALVULA (2) DOSIFICADORA, QUE MUESTRA UNA CAMARA (20) DE DOSIFICACION Y UN TUBITO (21) DE VALVULA. EN UNA PRIMERA POSICION DEL TUBITO DE VALVULA LA CAMARA DOSIFICADORA SE ENCUENTRA EN UNION CON EL ESPACIO INTERIOR DE RECIPIENTE Y ESTA RELLENO CON UNA CANTIDAD DETERMINADA PREVIAMENTE DE AEROSOL. EN UNA SEGUNDA POSICION DEL TUBITO DE VALVULA SE LIBERA LA CANTIDAD DE AEROSOL QUE SE ENCUENTRA EN LA CAMARA DOSIFICADORA. EL GAS DE IMPULSION ES UN GAS ALTERNATIVO LIBRE DE HIDROCARBUROS FLUOCLORADOS, CON PREFERENCIA UN GAS DE IMPULSION QUE ABARCA SOLAMENTE FLUORHIDROCARBURO, Y LA PARED INTERIOR DEL RECIPIENTE ESTA RECUBIERTA CON UNA CAPA DE PLASTICO.
ES94810478T 1993-08-27 1994-08-18 Recipiente para aerosol con gas propulsor exento de cfc y valvula dosificadora asi como su empleo. Expired - Lifetime ES2113074T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93810614 1993-08-27

Publications (1)

Publication Number Publication Date
ES2113074T3 true ES2113074T3 (es) 1998-04-16

Family

ID=8215022

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94810478T Expired - Lifetime ES2113074T3 (es) 1993-08-27 1994-08-18 Recipiente para aerosol con gas propulsor exento de cfc y valvula dosificadora asi como su empleo.

Country Status (11)

Country Link
US (2) US6596260B1 (es)
EP (1) EP0642992B1 (es)
JP (1) JP3610438B2 (es)
AT (1) ATE163623T1 (es)
AU (1) AU690913B2 (es)
CA (1) CA2130867C (es)
DE (1) DE59405357D1 (es)
DK (1) DK0642992T3 (es)
ES (1) ES2113074T3 (es)
GR (1) GR3026507T3 (es)
HK (1) HK1010716A1 (es)

Families Citing this family (141)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6596260B1 (en) * 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
AU751859B2 (en) * 1995-04-14 2002-08-29 Smithkline Beecham Corporation Metered dose inhaler for beclomethasone dipropionate
ATE258813T1 (de) * 1995-04-14 2004-02-15 Smithkline Beecham Corp Vorrichtung zur dosierten inhalierung von beclomethason-diproprionat
AU752682B2 (en) * 1995-04-14 2002-09-26 Smithkline Beecham Corporation Metered dose inhaler for salmeterol
CN1217654C (zh) 1995-04-14 2005-09-07 史密丝克莱恩比彻姆公司 舒喘宁的计定剂量吸入器
AU2002301285B2 (en) * 1995-04-14 2005-09-08 Smithkline Beecham Corporation Metered dose inhaler for fluticasone propionate
ATE297773T1 (de) 1995-04-14 2005-07-15 Smithkline Beecham Corp Dosierinhalator für salmeterol
CN1113675C (zh) * 1995-04-14 2003-07-09 葛兰素惠尔康公司 丙酸福地卡松的计定剂量吸入器
EP0778001B1 (en) * 1995-05-12 2004-04-07 Seiko Epson Corporation Apparatus for diagnosing condition of living organism and control unit
FR2740527B1 (fr) * 1995-10-31 1998-01-02 Valois Tige de soupape a faibles frottements
US5871010A (en) * 1996-06-10 1999-02-16 Sarnoff Corporation Inhaler apparatus with modified surfaces for enhanced release of dry powders
GB9626960D0 (en) * 1996-12-27 1997-02-12 Glaxo Group Ltd Valve for aerosol container
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
GB2329939A (en) 1997-06-26 1999-04-07 Glaxo Group Ltd Self-lubricating valve stem for aerosol containers
GB2322847A (en) * 1997-11-05 1998-09-09 Bespak Plc Metering valve
DK1066073T4 (da) 1998-02-23 2008-06-16 Glaxo Group Ltd Dispensertrykbeholdere
GB9814717D0 (en) * 1998-02-23 1998-09-02 Bespak Plc Improvements in drug delivery devices
GB9805938D0 (en) * 1998-03-19 1998-05-13 Glaxo Group Ltd Valve for aerosol container
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
GB9904919D0 (en) 1999-03-03 1999-04-28 Novartis Ag Organic compounds
US6315985B1 (en) 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
GB9918627D0 (en) 1999-08-07 1999-10-13 Glaxo Group Ltd Valve
FR2798367B1 (fr) * 1999-09-15 2001-11-23 Valois Sa Joint de soupape pour valve doseuse
IL150397A0 (en) * 2000-01-14 2002-12-01 Astrazeneca Ab A method for applying a polymer coating to the internal surface of a container
DE10004465A1 (de) * 2000-02-02 2001-08-16 Pari Gmbh Inhalationsvernebler
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
US20030183223A1 (en) * 2000-03-01 2003-10-02 Hailey Andrew Mark Metered dose inhaler
JP2003525099A (ja) 2000-03-01 2003-08-26 グラクソ グループ リミテッド 定量噴霧式吸入器
AU2000250701B2 (en) 2000-05-22 2004-07-01 Chiesi Farmaceutici S.P.A. Stable pharmaceutical solution formulations for pressurised metered dose inhalers
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
TW523409B (en) 2000-09-15 2003-03-11 Baxter Int Container for inhalation anesthetic
US20030207057A1 (en) * 2000-09-18 2003-11-06 Britto Ignatius Loy Metered dose inhaler can coated two or more times with fluorocarbon polymers
GB0025092D0 (en) * 2000-10-13 2000-11-29 Glaxo Group Ltd Medicament dispenser
SE0004610D0 (sv) 2000-12-13 2000-12-13 Astrazeneca Ab Surface modification process
NZ526564A (en) * 2000-12-22 2004-12-24 Glaxo Group Ltd Metered dose inhaler for salmeterol xinafoate
GB0106046D0 (en) * 2001-03-12 2001-05-02 Glaxo Group Ltd Canister
SI1273292T1 (en) 2001-07-02 2004-12-31 Chiesi Farmaceutici S.P.A. Optimised formulation of tobramycin for aerosolization
JP2005504090A (ja) 2001-09-26 2005-02-10 バクスター・インターナショナル・インコーポレイテッド 分散体および溶媒相または液相の除去によるサブミクロンサイズ−ナノ粒子の調製
GB0125380D0 (en) * 2001-10-23 2001-12-12 Glaxo Group Ltd Medicament dispenser
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
CA2502986C (en) 2002-10-25 2011-08-23 Foamix Ltd. Cosmetic and pharmaceutical foam
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
FR2856990A1 (fr) * 2003-07-02 2005-01-07 Valois Sas Valve de distribution de produits fluides et distributeur comportant une telle valve
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
GB0405634D0 (en) * 2004-03-12 2004-04-21 Univ Southampton Anti-virus therapy for respiratory diseases
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
GB0425518D0 (en) 2004-11-19 2004-12-22 Clinical Designs Ltd Substance source
CA2590839A1 (en) * 2004-12-15 2006-06-22 3M Innovative Properties Company Elastomer seals for use in medicinal aerosol devices
GB0428204D0 (en) * 2004-12-23 2005-01-26 Clinical Designs Ltd Medicament container
US20070069046A1 (en) * 2005-04-19 2007-03-29 Foamix Ltd. Apparatus and method for releasing a measure of content from a plurality of containers
FR2885889B1 (fr) * 2005-05-20 2007-10-19 Valois Sas Valve de distribution de produit fluide
AU2006277929B2 (en) * 2005-08-08 2010-07-15 Novartis Ag Insulated canister for metered dose inhalers
US8367734B1 (en) 2005-08-11 2013-02-05 Amphastar Pharmaceuticals Inc. Stable epinephrine suspension formulation with high inhalation delivery efficiency
US20070272768A1 (en) * 2006-05-26 2007-11-29 Williams Donald R Water-Based Airless Adhesive Application Container
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009056991A2 (en) * 2007-09-04 2009-05-07 Foamix Ltd. Device for delivery of a foamable composition
GB0721737D0 (en) * 2007-11-06 2007-12-19 3M Innovative Properties Co Medicinal inhalation devices and components thereof
AU2008323924B2 (en) * 2007-11-06 2013-01-17 3M Innovative Properties Company Medicinal inhalation devices and components thereof
GB0721739D0 (en) * 2007-11-06 2007-12-19 3M Innovative Properties Co medicinal inhalation devices and components thereof
US20090130046A1 (en) * 2007-11-20 2009-05-21 S.C Johnson & Son, Inc. Concentrated Fragrance Composition Provided in Metered Aerosol Spray
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
US8518376B2 (en) 2007-12-07 2013-08-27 Foamix Ltd. Oil-based foamable carriers and formulations
US8227027B2 (en) * 2007-12-07 2012-07-24 Presspart Gmbh & Co. Kg Method for applying a polymer coating to an internal surface of a container
WO2009090495A2 (en) 2007-12-07 2009-07-23 Foamix Ltd. Oil and liquid silicone foamable carriers and formulations
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
WO2009087224A1 (en) 2008-01-11 2009-07-16 Novartis Ag Pyrimidines as kinase inhibitors
WO2009090558A2 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
GB0904059D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
GB0904040D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
EP2236227B1 (de) 2009-03-30 2013-12-18 Boehringer Ingelheim International GmbH Umformwerkzeug mit einem rotierbaren Grundkörper
EP2236224B1 (de) * 2009-03-30 2013-03-06 Boehringer Ingelheim International GmbH Umformwerkzeug mit einem rotierbaren Grundkörper zum Formen einer Inhalatorkartusche und Verwendung eines solchen Umformwerkzeugs
EP2662472B1 (de) 2009-03-31 2019-02-27 Boehringer Ingelheim International Gmbh Verfahren zur Beschichtung einer Oberfläche eines Bauteils
CA2662490C (en) * 2009-04-15 2016-07-19 Klenzoid Company Limited Polymer delivery system and method for waste water facility
CA2760186C (en) 2009-04-28 2019-10-29 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
US20120097159A1 (en) 2009-05-06 2012-04-26 Suresh Iyer Medicinal inhalation devices and components thereof
US9278048B2 (en) * 2009-05-06 2016-03-08 Baxter International, Inc. Pharmaceutical product and method of use
CN102460635B (zh) 2009-05-06 2014-12-24 3M创新有限公司 对容器进行等离子体处理的装置和方法
US8815325B2 (en) 2009-05-06 2014-08-26 3M Innovative Properties Company Medicinal inhalation device
US9265910B2 (en) 2009-05-18 2016-02-23 Boehringer Ingelheim International Gmbh Adapter, inhalation device, and nebulizer
DE102009022318A1 (de) * 2009-05-22 2010-12-23 Schott Solar Ag Verfahren zur Herstellung eines photovoltaischen Moduls
EP2457181A4 (en) 2009-07-24 2013-01-23 Digimarc Corp IMPROVED AUDIO / VIDEO PROCESSES AND SYSTEMS
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
MX359879B (es) 2009-10-02 2018-10-12 Foamix Pharmaceuticals Ltd Composiciones tópicas de tetraciclina.
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
GB0918149D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved medicinal aerosol formulation
GB0918150D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved formulations
JP5658268B2 (ja) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
EP2504052B1 (en) 2009-11-25 2022-07-27 Boehringer Ingelheim International GmbH Nebulizer
GB201003273D0 (en) 2010-02-26 2010-04-14 Portal Medical Ltd Medicament dispenser device
GB201003275D0 (en) 2010-02-26 2010-04-14 Portal Medical Ltd Method of manufacturing a medicament dispenser device
EP2585151B1 (en) 2010-06-24 2018-04-04 Boehringer Ingelheim International GmbH Nebulizer
FR2961795A1 (fr) 2010-06-28 2011-12-30 Lindal France Sas Valve de dosage pour flacon sous pression
WO2012007843A2 (en) 2010-07-12 2012-01-19 Foamix Ltd. Apparatus and method for releasing a unit dose of content from a container
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
SG10201510159XA (en) * 2010-12-10 2016-01-28 Advanced Tech Materials Generally cylindrically-shaped liner for use in pressure dispense systems and methods of manufacturing the same
EP2694220B1 (de) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
US20120318827A1 (en) * 2011-06-15 2012-12-20 Steven Schennum Canister
US8883819B2 (en) 2011-09-01 2014-11-11 Irm Llc Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
US20140171404A1 (en) 2012-12-19 2014-06-19 Novartis Ag Autotaxin inhibitors
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
BR112016000779A8 (pt) 2013-07-18 2020-01-07 Novartis Ag inibidores de autotaxina que compreendem núcleo do ciclo de benzilamida de anel heteroaromático, seus usos, composição e combinação farmacêuticas
WO2015008229A1 (en) 2013-07-18 2015-01-22 Novartis Ag Autotaxin inhibitors
ES2836977T3 (es) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizador
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
WO2015162558A1 (en) 2014-04-24 2015-10-29 Novartis Ag Autotaxin inhibitors
ES2667424T3 (es) 2014-04-24 2018-05-10 Novartis Ag Derivados de pirazina como inhibidores de fosfatidil-inositol-3-quinasa
US10112926B2 (en) 2014-04-24 2018-10-30 Novartis Ag Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitors
BR112016024533A8 (pt) 2014-04-24 2021-03-30 Novartis Ag derivados de amino pirazina como inibidores de fosfatidilinositol 3-cinase ou sal, seu uso, e composição e combinação farmacêuticas
ES2954961T3 (es) 2014-05-07 2023-11-27 Boehringer Ingelheim Int Unidad, nebulizador y método
DK3139984T3 (da) 2014-05-07 2021-07-19 Boehringer Ingelheim Int Forstøver
RS64124B1 (sr) 2014-05-07 2023-05-31 Boehringer Ingelheim Int Inhalator i kontejner
US20170088545A1 (en) 2014-05-14 2017-03-30 Novartis Ag Carboxamide inhibitors
WO2015173659A2 (en) 2014-05-14 2015-11-19 Novartis Ag Carboxamide derivatives
FR3049275B1 (fr) * 2016-03-23 2019-07-19 Aptar France Sas Valve doseuse et dispositif de distribution de produit fluide comportant une telle valve
MX2020012139A (es) 2016-09-08 2021-01-29 Vyne Pharmaceuticals Inc Composiciones y metodos para tratar rosacea y acne.
DE112017007053T5 (de) 2017-02-14 2019-10-31 Presspart Gmbh & Co. Kg Verfahren zum dichtenden Verbinden eines Kanisters und einer oberen Abdeckung
FR3065891B1 (fr) * 2017-05-05 2021-12-24 Aptar France Sas Valve doseuse et dispositif de distribution de produit fluide comportant une telle valve.
GB201717996D0 (en) * 2017-10-31 2017-12-13 Portal Medical Ltd Medicament dispenser device
EP3756711A1 (en) 2019-06-25 2020-12-30 Presspart Gmbh & Co. Kg Method of plasma cleaning and coating of mdi cans
CN113038982A (zh) * 2019-07-29 2021-06-25 上海谷森医药有限公司 用于雾化吸入的、具有单层容器和喷嘴形帽的盒

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2815889A (en) 1955-07-28 1957-12-10 Engine Parts Mfg Company Metering device controlling discharge of fluids from aerosol containers
US2886217A (en) 1957-05-20 1959-05-12 Riker Laboratories Inc Dispensing device
US3324069A (en) * 1964-10-23 1967-06-06 Pennsalt Chemicals Corp Vinylidene fluoride polymer dispersions
GB1064840A (en) 1964-11-23 1967-04-12 Du Pont Tetrafluoroethylene/hexafluoropropylene copolymer dispersions
DE1226251B (de) 1965-07-10 1966-10-06 Siegfried Witte Verwendung von Kunststoff zum Herstellen oder Auskleiden von Gefaessen fuer fluessiges Metall oder Legierungen
FR1584784A (es) * 1968-08-13 1970-01-02
GB1415778A (en) 1973-04-16 1975-11-26 Ici Ltd Increasing the molecular weight of aromatic polysulphones
JPS515447B2 (es) 1971-08-31 1976-02-20
NL167983C (nl) * 1973-11-19 1982-02-16 Ici Ltd Werkwijze voor de bereiding van een bekledingsmateriaal en de onder toepassing daarvan beklede voorwerpen.
FR2267496A1 (en) 1974-04-11 1975-11-07 Sidel Sa Method of sealing valve on aerosol container - uses internally ribbed sleeve over ribbed valve and sleeve
CH628355A5 (de) 1976-02-24 1982-02-26 Ciba Geigy Ag Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.
GB2077229B (en) 1980-05-16 1983-08-03 Neotechnic Eng Ltd Valve assembly for a pressurized aerosoldispensing container
JPH0335399Y2 (es) 1985-11-08 1991-07-26
DE68915203T2 (de) 1988-03-22 1994-09-22 Fisons Plc Pharmazeutische Mischungen.
FI94342C (fi) * 1988-03-29 1995-08-25 Ciba Geigy Ag Menetelmä uusien alkanofenonien valmistamiseksi
US5149717A (en) 1988-03-29 1992-09-22 Ciba-Geigy Corporation Alkanophenones useful for treating allergies
US4902318A (en) 1988-05-25 1990-02-20 The United States Of America As Represented By The Administrator Of The Environmental Protection Agency Inlet apparatus for gas-aerosol sampling
JP2517748B2 (ja) 1988-07-12 1996-07-24 株式会社大阪造船所 エアゾ―ル缶
US5290539A (en) 1990-12-21 1994-03-01 Minnesota Mining And Manufacturing Company Device for delivering an aerosol
IL104068A (en) 1991-12-12 1998-10-30 Glaxo Group Ltd Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant
US5349947A (en) * 1993-07-15 1994-09-27 Newhouse Michael T Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow
US6596260B1 (en) * 1993-08-27 2003-07-22 Novartis Corporation Aerosol container and a method for storage and administration of a predetermined amount of a pharmaceutically active aerosol
US7341345B2 (en) 2004-07-19 2008-03-11 Massachusetts Eye & Ear Infirmary Ocular wavefront-correction profiling
JP4736867B2 (ja) 2006-03-07 2011-07-27 オイレス工業株式会社 鍔付円筒軸受ブッシュ及びその製造方法並びに該鍔付円筒軸受ブッシュを用いたヒンジ構造
JP4833021B2 (ja) 2006-10-26 2011-12-07 株式会社フジクラ 波形表示装置、波形表示方法、及び波形表示プログラム

Also Published As

Publication number Publication date
CA2130867A1 (en) 1995-02-28
AU7142994A (en) 1995-03-09
GR3026507T3 (en) 1998-07-31
EP0642992B1 (de) 1998-03-04
US20030194379A1 (en) 2003-10-16
CA2130867C (en) 2006-07-11
DK0642992T3 (da) 1998-12-07
US6596260B1 (en) 2003-07-22
HK1010716A1 (en) 1999-06-25
JPH0776380A (ja) 1995-03-20
ATE163623T1 (de) 1998-03-15
US8119105B2 (en) 2012-02-21
EP0642992A2 (de) 1995-03-15
DE59405357D1 (de) 1998-04-09
AU690913B2 (en) 1998-05-07
JP3610438B2 (ja) 2005-01-12
EP0642992A3 (de) 1995-03-22

Similar Documents

Publication Publication Date Title
ES2113074T3 (es) Recipiente para aerosol con gas propulsor exento de cfc y valvula dosificadora asi como su empleo.
US4322020A (en) Invertible pump sprayer
BR9714091A (pt) Válvula para um recipiente de aerossol para dispensa de uma substância em um propelente lìquido contido do mesmo, e, recipiente de aerossol.
ES2178817T3 (es) Formulaciones medicinales de aerosol.
BG103221A (en) Pharmaceutical composition in aerosol form
WO2001098176A3 (en) Package for a pressurized container containing a drug
JPH02261888A (ja) 加圧ガスパックおよびエーロゾル用噴射剤
ZA200100408B (en) Medicinal aerosol formulations.
MXPA03000276A (es) Nueva formulacion en aerosol que contiene una molecula fluorada polar.
ES2093493T3 (es) Distribuidor de espuma bajo presion.
TR199700957T1 (xx) Farmas�tik bile�imler ve uygulanmalar� i�in cihazlar.
IT1317720B1 (it) Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
US3287214A (en) Surface disinfectant and space deodorant aerosol spray compositions
US5552088A (en) Non-ozone depleting malodorous composition of matter and warning system
JP2795354B2 (ja) 人体用エアゾール製品
US3460351A (en) Device to accelerate the boiling of a liquefied gas
CA2200240A1 (en) Agent dispenser and method and apparatus for introducing an agent into aliquid or gas at a controlled rate
US7841490B2 (en) Mixture of low-boiling liquids with products dispensable by pumps
US5340538A (en) Sterilizing gas delivery method
JP3378643B2 (ja) 粉末消火剤エアゾール式簡易消火具の製造法
JPH05201477A (ja) エアゾール装置
JP2001172616A (ja) 全量噴射型のエアゾール製品
JPS5689532A (en) Formation of foamable body
JPS5718776A (en) Propellant for spraying substance in spraying vessel
IT1259466B (it) Bomboletta ricaricabile per la nebulizzazione di miscele liquide.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 642992

Country of ref document: ES