ES2112258T3 - Gen y proteina precursora del cnp porcino. - Google Patents

Gen y proteina precursora del cnp porcino.

Info

Publication number
ES2112258T3
ES2112258T3 ES91111630T ES91111630T ES2112258T3 ES 2112258 T3 ES2112258 T3 ES 2112258T3 ES 91111630 T ES91111630 T ES 91111630T ES 91111630 T ES91111630 T ES 91111630T ES 2112258 T3 ES2112258 T3 ES 2112258T3
Authority
ES
Spain
Prior art keywords
leu
gly
lys
ala
pro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91111630T
Other languages
English (en)
Inventor
Hisayuki Matsuo
Kenji Kangawa
Naoto Minamino
Shoji Tanaka
Kayoko Kawashima
Yasunori Tawaragi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of ES2112258T3 publication Critical patent/ES2112258T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

SE PRESENTA EL GEN Y EL CADN DE UN CNP (PEPTIDO NATRIURETICO DE TIPO C) DERIVADO DE PORCINO, Y UNA PROTEINA PRECURSORA DE CNP DERIVADO DE PORCINO Y SUS DERIVADOS. EL PRECURSOR DE CNP DERIVADO DE PORCINO SE REPRESENTA POR LA SIGUIENTE SECUENCIA DE AMINO ACIDO: ESTOS DERIVADOS SON NUEVOS Y TIENEN ACTIVIDADES NATRIURETICAS E HIPOTENSORAS.
ES91111630T 1990-07-13 1991-07-12 Gen y proteina precursora del cnp porcino. Expired - Lifetime ES2112258T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2186583A JP3026351B2 (ja) 1990-07-13 1990-07-13 ブタｃｎｐ遺伝子及び前駆体蛋白

Publications (1)

Publication Number Publication Date
ES2112258T3 true ES2112258T3 (es) 1998-04-01

Family

ID=16191085

Family Applications (2)

Application Number Title Priority Date Filing Date
ES96117857T Expired - Lifetime ES2303336T3 (es) 1990-07-13 1991-07-12 Cnp-gen del cerdo y proteina precursora.
ES91111630T Expired - Lifetime ES2112258T3 (es) 1990-07-13 1991-07-12 Gen y proteina precursora del cnp porcino.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES96117857T Expired - Lifetime ES2303336T3 (es) 1990-07-13 1991-07-12 Cnp-gen del cerdo y proteina precursora.

Country Status (8)

Country Link
US (1) US6020168A (es)
EP (2) EP0771875B1 (es)
JP (1) JP3026351B2 (es)
AT (2) ATE162201T1 (es)
DE (2) DE69133591T2 (es)
DK (1) DK0466175T3 (es)
ES (2) ES2303336T3 (es)
GR (1) GR3026553T3 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3026352B2 (ja) * 1990-09-11 2000-03-27 壽之 松尾 ラットＣＮＰｃＤＮＡ及び前駆体蛋白
AU3749293A (en) * 1992-03-18 1993-10-21 Wolf-Georg Forssmann DNA coding for aphrodisin
IL142118A0 (en) * 2001-03-20 2002-03-10 Prochon Biotech Ltd Method and composition for treatment of skeletal dysplasias
HUE039448T2 (hu) 2004-04-21 2018-12-28 Alexion Pharma Inc Csontba szállító konjugátumok és alkalmazási módszerük a fehérjék csontba juttatására
AR069409A1 (es) 2007-11-21 2010-01-20 Biomarin Pharm Inc Variantes de peptidos natriureticos de tipo c
HUE032582T2 (en) 2009-05-20 2017-09-28 Biomarin Pharm Inc Variants of C-type natriuretic peptide
US9266939B2 (en) 2010-12-27 2016-02-23 Alexion Pharmaceuticals, Inc. Compositions comprising natriuretic peptides and methods of use thereof
WO2013058833A1 (en) 2011-10-19 2013-04-25 Enobia Canada Limited Partnership Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
US20150293119A1 (en) * 2011-12-23 2015-10-15 Mayo Foundation For Medical Education And Research Assessing renal structural alterations and outcomes
US10052366B2 (en) 2012-05-21 2018-08-21 Alexion Pharmaceuticsl, Inc. Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
WO2016007873A1 (en) 2014-07-11 2016-01-14 The Regents Of The University Of Michigan Compositions and methods for treating craniosynostosis
JP6787894B2 (ja) 2014-12-05 2020-11-18 アレクシオン ファーマシューティカルズ， インコーポレイテッド 組換えアルカリホスファターゼを用いた発作の処置
AU2016211447B2 (en) 2015-01-28 2021-09-23 Alexion Pharmaceuticals, Inc. Methods of treating a subject with an alkaline phosphatase deficiency
CN112924699A (zh) * 2015-03-30 2021-06-08 国立大学法人神户大学 动物物种的鉴定方法
KR102644116B1 (ko) 2015-08-17 2024-03-05 알렉시온 파마슈티칼스, 인코포레이티드 알칼린 포스파타제의 제조
JP6868617B2 (ja) 2015-09-28 2021-05-12 アレクシオン ファーマシューティカルズ， インコーポレイテッド 低ホスファターゼ血症の組織非特異的アルカリホスファターゼ（ｔｎｓａｌｐ）酵素補充療法に有効な投薬計画の特定
JP2018533571A (ja) 2015-10-30 2018-11-15 アレクシオン ファーマシューティカルズ， インコーポレイテッド 患者の頭蓋縫合早期癒合症を治療するための方法
WO2017155569A1 (en) 2016-03-08 2017-09-14 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia in children
US10898549B2 (en) 2016-04-01 2021-01-26 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia in adolescents and adults
WO2017173413A1 (en) 2016-04-01 2017-10-05 Alexion Pharmaceuticals, Inc. Treating muscle weakness with alkaline phosphatases
WO2017214130A1 (en) 2016-06-06 2017-12-14 Alexion Pharmaceuticals, Inc. Metal impact on manufacturing of alkaline phosphatases
WO2018035420A1 (en) 2016-08-18 2018-02-22 Alexion Pharmaceuticals, Inc. Methods for treating tracheobronchomalacia
CN110719786A (zh) 2017-03-31 2020-01-21 阿雷克森制药公司 用于治疗成人和青少年的低磷酸酯酶症(hpp)的方法
JP2021519590A (ja) 2018-03-30 2021-08-12 アレクシオン ファーマシューティカルズ， インコーポレイテッド 糖タンパク質の製造

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60136596A (ja) 1983-12-26 1985-07-20 Suntory Ltd ペプチド及びこれを有効成分とする利尿剤
JPH0794473B2 (ja) 1984-03-02 1995-10-11 サントリー株式会社 新規なペプチド及びこれを有効成分とする利尿剤
JPS60184098A (ja) 1984-03-02 1985-09-19 Suntory Ltd 新規なペプチド及びこれを有効成分とする利尿剤
JPS60260596A (ja) 1984-06-08 1985-12-23 Toshiyuki Matsuo 新規なペプチド及びこれを有効成分とする医薬
JPS617298A (ja) 1984-06-22 1986-01-13 Toshiyuki Matsuo 新規なペプチド及びこれを有効成分とする医薬

Also Published As

Publication number Publication date
DE69128664D1 (de) 1998-02-19
DE69133591D1 (de) 2008-03-27
JP3026351B2 (ja) 2000-03-27
EP0771875A1 (en) 1997-05-07
GR3026553T3 (en) 1998-07-31
JPH0474199A (ja) 1992-03-09
EP0466175A1 (en) 1992-01-15
EP0771875B1 (en) 2008-02-13
ATE386118T1 (de) 2008-03-15
ES2303336T3 (es) 2008-08-01
DK0466175T3 (da) 1998-09-07
DE69133591T2 (de) 2009-02-05
EP0466175B1 (en) 1998-01-14
US6020168A (en) 2000-02-01
DE69128664T2 (de) 1998-06-04
ATE162201T1 (de) 1998-01-15

Similar Documents

Publication Publication Date Title
ES2112258T3 (es) Gen y proteina precursora del cnp porcino.
NL300013I1 (nl) Nieuwe protein met TNF-remmende werking en hun ber
ATE528014T1 (de) Polypeptid mit modifizierten kunitz domains
MD1652F2 (en) Protein possessing the cytokin - type activity, recombinant DNA-codifyer for such protein, transformed cells and microorganism, expression vector, process for protein obtaining and remedy containing such a protein
DE3486154D1 (de) Cardiodilatin, ein neues peptidhormon und verfahren zu seiner herstellung.
FI943235A0 (fi) Uusi ihmisen Kunitz-tyyppinen proteaasiestäjä ja sen muunnnoksia
DK0466174T3 (da) Hidtil ukendt fysiologisk aktivt svinepeptid (CNP-53)
DK0475394T3 (da) Rotte C-type natriuretisk peptid cDNA, og precursorprotein
DE69201438D1 (en) Als therapeutika geeignete peptide.
EP0292257A3 (en) Peptides having anf activity
DE3751398T2 (de) Substrat-Peptide.
EP0687685A4 (en) PHYSIOLOGICALLY ACTIVE PEPTIDES
ES8605987A1 (es) Procedimiento para preparar polipeptidos inmunoterapeuticos
IT1177963B (it) Agenti polipeptidici immunoterapeutici e procedimento di preparazione

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 466175

Country of ref document: ES