ES2102518T3 - Motor de atraccion por gravitacion para el agrupamiento autoadaptativo de corrientes de datos n-dimensionales. - Google Patents

Motor de atraccion por gravitacion para el agrupamiento autoadaptativo de corrientes de datos n-dimensionales.

Info

Publication number
ES2102518T3
ES2102518T3 ES92919706T ES92919706T ES2102518T3 ES 2102518 T3 ES2102518 T3 ES 2102518T3 ES 92919706 T ES92919706 T ES 92919706T ES 92919706 T ES92919706 T ES 92919706T ES 2102518 T3 ES2102518 T3 ES 2102518T3
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ES
Spain
Prior art keywords
self
dimensional data
pct
data currents
adaptive grouping
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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ES92919706T
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English (en)
Inventor
Pierre Bierre
Ron A Mickaels
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Becton Dickinson and Co
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Becton Dickinson and Co
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Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of ES2102518T3 publication Critical patent/ES2102518T3/es
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10—Complex mathematical operations
    • G06F17/18—Complex mathematical operations for evaluating statistical data, e.g. average values, frequency distributions, probability functions, regression analysis
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G06F18/20—Analysing
    • G06F18/23—Clustering techniques
    • G06F18/232—Non-hierarchical techniques
    • G06F18/2321—Non-hierarchical techniques using statistics or function optimisation, e.g. modelling of probability density functions
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G06F18/20—Analysing
    • G06F18/23—Clustering techniques
    • G06F18/232—Non-hierarchical techniques
    • G06F18/2321—Non-hierarchical techniques using statistics or function optimisation, e.g. modelling of probability density functions
    • G06F18/23211—Non-hierarchical techniques using statistics or function optimisation, e.g. modelling of probability density functions with adaptive number of clusters
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/698—Matching; Classification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1488—Methods for deciding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Abstract

LA INVENCION SE REFIERE A UN METODO PARA AUTOAGRUPAR CORRIENTES DE DATOS DE DIMENSION N, DESCRITA COMO UNA MAQUINA DE ATRACCION POR GRAVEDAD, QUE CONSISTE EN UN ATRACTOR GRAVITACIONAL QUE TIENE UN LIMITE GEOMETRICO. LA CORRIENTE DE DATOS (5) ES ANALIZADA PARA FINES DE CENTRAR CON PRECISION CADA SUPERFICIE LIMITE (2) DEL MIEMBRO DEL ATRACTOR ALREDEDOR DEL CENTRO ESTADISTICO DE MASA (1) DEL GRUPO DE DATOS QUE SE PRETENDE CLASIFICAR. LA INVENCION TIENE UTILIDAD PARTICULAR PARA ANALIZAR DATOS DE PARAMETROS MULTIPLES PROCEDENTES DE UN CITOMETRO DE FLUJO, Y MAS PARTICULARMENTE TIENE UTILIDAD PARA ANALIZAR DATOS PROCEDENTES DE TODAS LAS CELULAS DE LA SANGRE ETIQUETADAS CON ANTICUERPOS MONOCLONALES CD3, CD4 Y CD8 MARCADOS FLUORESCENTEMENTE, PARA LO CUAL HA SIDO AÑADIDO UN NUMERO CONOCIDO DE MICROPERLAS FLUORESCENTES.
ES92919706T 1991-08-28 1992-08-28 Motor de atraccion por gravitacion para el agrupamiento autoadaptativo de corrientes de datos n-dimensionales. Expired - Lifetime ES2102518T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75102091A 1991-08-28 1991-08-28

Publications (1)

Publication Number Publication Date
ES2102518T3 true ES2102518T3 (es) 1997-08-01

Family

ID=25020137

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92919706T Expired - Lifetime ES2102518T3 (es) 1991-08-28 1992-08-28 Motor de atraccion por gravitacion para el agrupamiento autoadaptativo de corrientes de datos n-dimensionales.

Country Status (7)

Country Link
US (2) US5627040A (es)
EP (1) EP0554447B1 (es)
JP (1) JP2581514B2 (es)
AT (1) ATE151546T1 (es)
DE (1) DE69218912T2 (es)
ES (1) ES2102518T3 (es)
WO (1) WO1993005478A1 (es)

Families Citing this family (172)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739000A (en) * 1991-08-28 1998-04-14 Becton Dickinson And Company Algorithmic engine for automated N-dimensional subset analysis
US5627040A (en) * 1991-08-28 1997-05-06 Becton Dickinson And Company Flow cytometric method for autoclustering cells
US5776709A (en) * 1991-08-28 1998-07-07 Becton Dickinson And Company Method for preparation and analysis of leukocytes in whole blood
EP0559208B1 (en) * 1992-03-05 2000-09-06 Becton, Dickinson and Company Method for preparation and analysis of leukocytes in whole blood utilizing flow cytometry
JP3165247B2 (ja) * 1992-06-19 2001-05-14 シスメックス株式会社 粒子分析方法及び装置
AUPN214095A0 (en) * 1995-04-03 1995-04-27 Australian Water Technologies Pty Ltd Method for detecting microorganisms using flow cytometry
JP3308441B2 (ja) * 1995-12-19 2002-07-29 シスメックス株式会社 尿中有形成分分析装置
DE69737883T2 (de) 1996-04-25 2008-03-06 Bioarray Solutions Ltd. Licht-regulierte, elektrokinetische zusammensetzung von partikeln an oberflächen
US6014904A (en) * 1996-05-09 2000-01-18 Becton, Dickinson And Company Method for classifying multi-parameter data
US6316215B1 (en) 1999-12-27 2001-11-13 Edwin L. Adair Methods of cancer screening utilizing fluorescence detection techniques and selectable imager charge integration periods
US6211477B1 (en) 1998-02-26 2001-04-03 Becton Dickinson And Company Electrostatic deceleration system for flow cytometer
FR2783326B1 (fr) * 1998-09-10 2000-12-01 Immunotech Sa Procede de detection ou de quantification des basophiles et des eosinophiles
US6495333B1 (en) * 1998-09-22 2002-12-17 Becton Dickinson And Company Flow cytometric, whole blood dendritic cell immune function assay
US7351546B2 (en) * 1998-09-22 2008-04-01 Becton, Dickinson And Company Flow cytometric, whole blood dendritic cell immune function assay
ES2178517B1 (es) * 1999-05-31 2004-09-16 Universidad De Salamanca Procedimiento para el estudio de la activacion funcional de leucocitos, plaquetas y otras celulas.
US6750037B2 (en) * 1999-12-27 2004-06-15 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
US6190877B1 (en) 1999-12-27 2001-02-20 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection and fluorescence detection techniques
US6984498B2 (en) * 1999-12-27 2006-01-10 Adair Edwin L Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
CA2403874A1 (en) 2000-03-28 2001-12-06 Dana-Farber Cancer Institute, Inc. Molecular database for antibody characterization
EP1295243A4 (en) 2000-05-11 2010-09-01 Becton Dickinson Co SYSTEM FOR IDENTIFYING CLUSTERS IN DISPERSION DIAGRAMS INVOLVING SMOOTH POLYGONS WITH OPTIMAL LIMITS
NZ522859A (en) 2000-06-19 2005-08-26 Correlogic Systems Inc Heuristic method of classifying objects using a vector space having multiple preclassified data clusters
JP4744778B2 (ja) 2000-06-21 2011-08-10 バイオアレイ ソルーションズ リミテッド 特定のランダム粒子アレイを適用した複数の被検体分子の分析方法
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
NZ524171A (en) 2000-07-18 2006-09-29 Correlogic Systems Inc A process for discriminating between biological states based on hidden patterns from biological data
US20040225326A1 (en) * 2001-05-07 2004-11-11 Weiner Mike L. Apparatus for the detection of restenosis
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
JP4751535B2 (ja) * 2001-07-26 2011-08-17 シスメックス株式会社 分画方法とそれを用いた血液分析装置
US6519033B1 (en) 2001-11-19 2003-02-11 Point Source Technologies, Llc Identification of particles in fluid
EP1281951A1 (en) * 2001-08-03 2003-02-05 PointSource Technologies, LLC Method and device for identification of particles in fluid
JP4377689B2 (ja) 2001-10-15 2009-12-02 バイオアレイ ソリューションズ リミテッド 同時尋問及び酵素仲介検出による多型遺伝子座の複合分析
US6838289B2 (en) * 2001-11-14 2005-01-04 Beckman Coulter, Inc. Analyte detection system
US6628386B2 (en) 2001-12-12 2003-09-30 Pointsource Technologies, Llc Particle detection beam
US6930769B1 (en) 2002-03-21 2005-08-16 Pointsource Technologies, Llc Optical sensor module tester
US7057724B1 (en) 2002-03-21 2006-06-06 Institute Of Critical Care Medicine Particulate info to field units
US6846311B2 (en) * 2002-04-02 2005-01-25 Acueity, Inc. Method and apparatus for in VIVO treatment of mammary ducts by light induced fluorescence
US6972424B1 (en) 2002-04-16 2005-12-06 Pointsource Technologies, Llc High detection rate particle identifier
US9943847B2 (en) 2002-04-17 2018-04-17 Cytonome/St, Llc Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
US6976590B2 (en) 2002-06-24 2005-12-20 Cytonome, Inc. Method and apparatus for sorting particles
US6808075B2 (en) 2002-04-17 2004-10-26 Cytonome, Inc. Method and apparatus for sorting particles
US20070065808A1 (en) * 2002-04-17 2007-03-22 Cytonome, Inc. Method and apparatus for sorting particles
US7157274B2 (en) * 2002-06-24 2007-01-02 Cytonome, Inc. Method and apparatus for sorting particles
ATE336266T1 (de) * 2002-06-21 2006-09-15 Adair Edwin Lloyd Anwendung von metalloporphyrinen zur behandlung von arteriosklerose
WO2004106887A2 (en) 2002-07-29 2004-12-09 Correlogic Systems, Inc. Quality assurance/quality control for high throughput bioassay process
EP2261868A2 (en) * 2002-08-20 2010-12-15 Cyvera Corporation Diffraction grating-based optical identification element and its applications
EP1535241A1 (en) * 2002-08-20 2005-06-01 Cyvera Corporation Diffraction grating-based optical identification element
US7164533B2 (en) * 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7900836B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7508608B2 (en) 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
US7901630B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7619819B2 (en) 2002-08-20 2009-11-17 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
US7872804B2 (en) 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
WO2004025563A1 (en) * 2002-09-12 2004-03-25 Cyvera Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
AU2003278827A1 (en) * 2002-09-12 2004-04-30 Cyvera Corp. Method and apparatus for labelling using diffraction grating-based encoded optical identification elements
AU2003274979A1 (en) * 2002-09-12 2004-04-30 Cyvera Corporation Chemical synthesis using diffraction grating-based encoded optical elements
US7092160B2 (en) 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
WO2004025560A1 (en) * 2002-09-12 2004-03-25 Cyvera Corporation Assay stick comprising coded microbeads
AU2003267192A1 (en) * 2002-09-12 2004-04-30 Cyvera Corporation Method and apparatus for aligning elongated microbeads in order to interrogate the same
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
EP1616286A1 (en) * 2003-04-02 2006-01-18 Amersham Biosciences UK Limited Method of, and computer software for, classification of cells into subpopulations
US6819421B1 (en) 2003-04-11 2004-11-16 Point Source Technologies, Llc Detection of new species of particles
US8185317B2 (en) * 2003-06-12 2012-05-22 Cytyc Corporation Method and system of determining the stain quality of slides using scatter plot distribution
US8321136B2 (en) * 2003-06-12 2012-11-27 Cytyc Corporation Method and system for classifying slides using scatter plot distribution
US20050048547A1 (en) * 2003-07-17 2005-03-03 Hongyu Zhao Classification of disease states using mass spectrometry data
US7353218B2 (en) * 2003-08-14 2008-04-01 International Business Machines Corporation Methods and apparatus for clustering evolving data streams through online and offline components
WO2005029705A2 (en) 2003-09-18 2005-03-31 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
NZ546072A (en) 2003-09-22 2009-08-28 Bioarray Solutions Ltd Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
WO2005042763A2 (en) 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
EP1694859B1 (en) 2003-10-29 2015-01-07 Bioarray Solutions Ltd Multiplexed nucleic acid analysis by fragmentation of double-stranded dna
CA2548842A1 (en) 2003-12-11 2005-07-07 Correlogic Systems, Inc. Method of diagnosing biological states through the use of a centralized, adaptive model, and remote sample processing
KR20060123539A (ko) * 2004-01-14 2006-12-01 루미넥스 코포레이션 측정시스템의 하나 이상의 매개변수를 변경하는 방법
WO2005072205A2 (en) * 2004-01-15 2005-08-11 Chemicon International, Inc. Image analysis and assay system
US7433123B2 (en) 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
US7315637B2 (en) * 2004-07-16 2008-01-01 Bioarray Solutions Ltd. Image processing and analysis of array data
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
AU2005307746B2 (en) 2004-11-16 2011-05-12 Illumina, Inc. And methods and apparatus for reading coded microbeads
US9260693B2 (en) 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
ES2609412T3 (es) * 2005-02-18 2017-04-20 Hematologics, Inc. Sistema para detectar células anómalas empleando un análisis multidimensional
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
GB2428471A (en) * 2005-07-18 2007-01-31 Mathshop Ltd Flow cytometry
CA2617678A1 (en) * 2005-08-02 2007-02-08 Luminex Corporation Methods, data structures, and systems for classifying microparticles
US20070043510A1 (en) * 2005-08-19 2007-02-22 Beckman Coulter, Inc. Assay system
WO2007117423A2 (en) * 2006-03-31 2007-10-18 Cira Discovery Sciences, Inc. Method and apparatus for representing multidimensional data
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
US20090105963A1 (en) * 2006-05-13 2009-04-23 Jesper Laursen Methods for Flow Cytometry Analyses of Un-Lysed Cells from Biological Fluids
CN101226190B (zh) * 2007-01-17 2013-07-03 深圳迈瑞生物医疗电子股份有限公司 流式细胞术的自动分类方法和装置
CA2691980C (en) 2007-06-29 2022-05-10 Correlogic Systems, Inc. Predictive markers for ovarian cancer
US20090269800A1 (en) * 2008-04-29 2009-10-29 Todd Covey Device and method for processing cell samples
US8140300B2 (en) * 2008-05-15 2012-03-20 Becton, Dickinson And Company High throughput flow cytometer operation with data quality assessment and control
US9183237B2 (en) 2008-07-10 2015-11-10 Nodality, Inc. Methods and apparatus related to gate boundaries within a data space
US20100014741A1 (en) * 2008-07-10 2010-01-21 Banville Steven C Methods and apparatus related to gate boundaries within a data space
US20100030719A1 (en) * 2008-07-10 2010-02-04 Covey Todd M Methods and apparatus related to bioinformatics data analysis
WO2010006303A2 (en) * 2008-07-10 2010-01-14 Nodality, Inc. Methods and apparatus related to management of experiments
FR2935802B1 (fr) * 2008-09-05 2012-12-28 Horiba Abx Sas Procede et dispositif de classification, de visualisation et d'exploration de donnees biologiques
US9034257B2 (en) * 2008-10-27 2015-05-19 Nodality, Inc. High throughput flow cytometry system and method
US20100204973A1 (en) * 2009-01-15 2010-08-12 Nodality, Inc., A Delaware Corporation Methods For Diagnosis, Prognosis And Treatment
US8688760B2 (en) 2010-02-18 2014-04-01 Becton, Dickinson And Company Determining population boundaries using radial density histograms
US9595099B2 (en) * 2010-02-26 2017-03-14 Carolyn M Salafia Automated placental measurement
EP3239717B1 (en) 2010-04-15 2020-05-27 Accellix Ltd System and method for determination of a medical condition
EP2684120A4 (en) * 2011-03-10 2015-05-06 Newsouth Innovations Pty Ltd ANALYSIS OF MULTIDIMENSIONAL CLUSTERS
ES2902648T3 (es) 2011-05-04 2022-03-29 Abbott Lab Método de análisis de glóbulos rojos nucleados y analizador hematológico automatizado
JP6104233B2 (ja) 2011-05-04 2017-03-29 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ 白血球分析システムおよび方法
JP6166716B2 (ja) 2011-05-04 2017-07-19 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ 好塩基球分析システムおよび方法
EP2724146B1 (en) 2011-06-24 2019-10-23 Becton, Dickinson and Company Absorbance spectrum scanning flow cytometry
US9336302B1 (en) 2012-07-20 2016-05-10 Zuci Realty Llc Insight and algorithmic clustering for automated synthesis
WO2014078741A1 (en) * 2012-11-16 2014-05-22 Beckman Coulter, Inc. Flow cytometry data segmentation result evaluation systems and methods
US10610861B2 (en) 2012-12-17 2020-04-07 Accellix Ltd. Systems, compositions and methods for detecting a biological condition
CN107941706A (zh) 2012-12-17 2018-04-20 伦珂德克斯有限公司 用于测定化学状态的系统和方法
US10088407B2 (en) 2013-05-17 2018-10-02 Becton, Dickinson And Company Systems and methods for efficient contours and gating in flow cytometry
US20170115297A1 (en) * 2014-04-03 2017-04-27 Tokyo Women's Medical University Method for Detecting SMN Protein Expression
WO2015160420A1 (en) 2014-04-14 2015-10-22 Becton, Dickinson And Company Reagent calibration system and method
CN107003225B (zh) 2014-12-04 2020-08-18 贝克顿·迪金森公司 流式细胞术细胞分选系统及其使用方法
US9709769B2 (en) 2014-12-10 2017-07-18 Becton, Dickinson And Company Methods for optically aligning light collection components and optically aligned light collection systems thereof
US10616219B2 (en) 2014-12-11 2020-04-07 FlowJo, LLC Single cell data management and analysis systems and methods
CN107209102B (zh) 2015-02-18 2021-03-02 贝克顿·迪金森公司 光学检测系统及其使用方法
WO2016205019A1 (en) 2015-06-17 2016-12-22 Becton, Dickinson And Company Optical detector scatter cap assembly having a removable scatter bar and methods of using the same
WO2017011549A1 (en) 2015-07-15 2017-01-19 Becton, Dickinson And Company System and method for label selection
US9830720B2 (en) 2015-09-02 2017-11-28 Becton, Dickinson And Company Graphics control during flow cytometry event gating
KR20230157532A (ko) 2015-10-13 2023-11-16 벡톤 디킨슨 앤드 컴퍼니 다중모드 형광 이미징 유동 세포 계측 시스템
US20190086319A1 (en) 2016-03-10 2019-03-21 Becton, Dickinson And Company Methods of evaluating a cellular sample for her-2/neu expression and compositions for practicing the same
KR102641469B1 (ko) 2016-03-17 2024-02-28 벡톤 디킨슨 앤드 컴퍼니 고효율 형광 유세포 분석기를 사용하는 세포 선별
CN105823765A (zh) * 2016-03-21 2016-08-03 天津大学 可扩展荧光寿命探测范围的质心算法cmm
CN109070083A (zh) 2016-04-22 2018-12-21 贝克顿迪金森公司 用于阵列产生的高密度沉积
WO2017197271A1 (en) 2016-05-12 2017-11-16 Bd Biosciences Fluorescence imaging flow cytometry with enhanced image resolution
EP3513167B1 (en) 2016-09-13 2023-05-24 Becton, Dickinson and Company Flow cytometer with optical equalization
CN116359503A (zh) 2016-09-19 2023-06-30 血液学有限公司 用于使用多维分析检测异常细胞的系统、方法和制品
CN109073530B (zh) 2016-10-03 2022-04-26 贝克顿·迪金森公司 用于确定流式细胞仪中的流体流的液滴延迟的方法和系统
US11205103B2 (en) 2016-12-09 2021-12-21 The Research Foundation for the State University Semisupervised autoencoder for sentiment analysis
EP3555630B1 (en) 2016-12-14 2023-05-31 Becton, Dickinson and Company Methods and compositions for obtaining a tuberculosis assessment in a subject
JP7058662B2 (ja) 2017-02-08 2022-04-22 ベクトン・ディキンソン・アンド・カンパニー 乾燥色素試薬装置、ならびにその製造及び使用方法
KR102608673B1 (ko) 2017-02-27 2023-11-30 벡톤 디킨슨 앤드 컴퍼니 광 검출 시스템 및 이의 사용 방법
WO2018217933A1 (en) 2017-05-25 2018-11-29 FlowJo, LLC Visualization, comparative analysis, and automated difference detection for large multi-parameter data sets
US11029242B2 (en) 2017-06-12 2021-06-08 Becton, Dickinson And Company Index sorting systems and methods
US10593082B2 (en) 2017-07-18 2020-03-17 Becton, Dickinson And Company Dynamic display of multi-parameter quantitative biological data
US10636182B2 (en) 2017-07-18 2020-04-28 Becton, Dickinson And Company Dynamic interactive display of multi-parameter quantitative biological data
EP3655753A1 (en) 2017-07-18 2020-05-27 Becton, Dickinson and Company Dynamic interactive display of multi-parameter quantitative biological data
CN111758019A (zh) 2018-01-23 2020-10-09 贝克顿·迪金森公司 用于动态光检测遮蔽的系统及其使用方法
JP2021519841A (ja) 2018-03-30 2021-08-12 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ ペンダントクロモフォアを有する水溶性ポリマー色素
WO2019209723A1 (en) * 2018-04-26 2019-10-31 Becton, Dickinson And Company Characterization and sorting for particle analyzers
JP7374124B2 (ja) 2018-04-27 2023-11-06 ベクトン・ディキンソン・アンド・カンパニー フローサイトメトリで選別された試料のための収集システムおよびそれを使用する方法
US10883912B2 (en) 2018-06-04 2021-01-05 Becton, Dickinson And Company Biexponential transformation for graphics display
WO2019245709A1 (en) 2018-06-19 2019-12-26 Becton, Dickinson And Company Variable multiplexing switches for detector arrays, systems and methods of use thereof
WO2020005430A1 (en) 2018-06-28 2020-01-02 Becton, Dickinson And Company Integrated pre-amplification light detection systems and methods of use thereof
JP2021534401A (ja) 2018-08-15 2021-12-09 ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company フロー式粒子分析器のための流量および真空制御式流体管理システム
US20200105376A1 (en) 2018-10-01 2020-04-02 FlowJo, LLC Deep learning particle classification platform
US11035776B2 (en) 2018-10-30 2021-06-15 Becton, Dickinson And Company Particle sorting module with alignment window, systems and methods of use thereof
JP2022516233A (ja) 2018-12-28 2022-02-25 ベクトン・ディキンソン・アンド・カンパニー サンプルの蛍光物質をスペクトル的に分解する方法及びシステム
WO2020146733A1 (en) 2019-01-11 2020-07-16 Becton, Dickinson And Company Optimized sorting gates
WO2020163023A1 (en) 2019-02-08 2020-08-13 Becton, Dickinson And Company Droplet sorting decision modules, systems and methods of use thereof
EP3867626A4 (en) 2019-03-22 2022-11-09 Becton, Dickinson and Company SPECTRAL SEGREGATION OF FLUORESCENCE IMAGING USING RADIO FREQUENCY MULTIPLEXED EXCITATION DATA
JP7466563B2 (ja) 2019-03-29 2024-04-15 ベクトン・ディキンソン・アンド・カンパニー 粒子の区別に使用するためのパラメータ
US11143587B2 (en) 2019-04-02 2021-10-12 Becton, Dickinson And Company Compensation editor
WO2020219347A1 (en) 2019-04-21 2020-10-29 Becton, Dickinson And Company Cytometric bead array analysis
US11275026B2 (en) 2019-05-14 2022-03-15 Becton, Dickinson And Company Phase-calibration for imaging flow cytometry
JP2022536890A (ja) 2019-05-30 2022-08-22 ベクトン・ディキンソン・アンド・カンパニー 無線周波数多重信号の位相補正
WO2021007075A1 (en) 2019-07-10 2021-01-14 Becton, Dickinson And Company Reconfigurable integrated circuits for adjusting cell sorting classification
CN110543588A (zh) * 2019-08-27 2019-12-06 中国科学院软件研究所 一种面向大规模流数据的分布式聚类方法及系统
WO2021101692A1 (en) 2019-11-20 2021-05-27 Becton, Dickinson And Company A light detection module with adjustable sensitivity
WO2021127364A1 (en) 2019-12-20 2021-06-24 Becton, Dickinson And Company Methods for quantitating extra-cellular vesicle surface markers, and compositions for practicing the same
US20210230583A1 (en) 2020-01-29 2021-07-29 Becton, Dickinson And Company Barcoded wells for spatial mapping of single cells through sequencing
US20210278333A1 (en) 2020-01-31 2021-09-09 Becton, Dickinson And Company Methods and systems for adjusting a training gate to accommodate flow cytometer data
WO2021158400A1 (en) 2020-02-07 2021-08-12 Becton, Dickinson And Company Clustered wavelength division light detection systems and methods of using the same
JP2023516193A (ja) 2020-02-26 2023-04-18 ベクトン・ディキンソン・アンド・カンパニー 二次光散乱検出器を有する光検出システムおよびその使用方法
JP2023516192A (ja) 2020-02-27 2023-04-18 ベクトン・ディキンソン・アンド・カンパニー 細胞選別における飽和データ信号を識別するための方法及びそのためのシステム
CN115280134A (zh) 2020-03-17 2022-11-01 贝克顿·迪金森公司 用于光检测的增益匹配放大器
EP4143535A4 (en) 2020-04-28 2023-09-13 Becton, Dickinson and Company METHOD FOR SORTING UNIQUE PHENOTYPES AND CORRESPONDING SYSTEMS
EP4143536A4 (en) 2020-04-29 2023-11-01 Becton, Dickinson and Company SYNCHRONOUS MODULATION AND DETECTION METHODS IN A FLOW CYTOMETER AND ASSOCIATED SYSTEMS
EP4147029A4 (en) 2020-05-06 2023-11-01 Becton, Dickinson and Company METHODS AND SYSTEMS FOR CHARACTERIZING OVERFLOW SCATTERING IN FLOW CYTOMETER DATA
US20230046207A1 (en) 2021-08-10 2023-02-16 Becton, Dickinson And Company Outlet fittings for reducing bubbles at the interface with a flow cell, and flow cytometers and methods using the same
US20230053122A1 (en) 2021-08-10 2023-02-16 Becton, Dickinson And Company Clamps for operably coupling an optical component to a mounting block, and methods and systems for using the same
CN114115341B (zh) * 2021-11-18 2022-11-01 中国人民解放军陆军工程大学 一种智能体集群协同运动方法及系统

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599307A (en) * 1983-07-18 1986-07-08 Becton, Dickinson And Company Method for elimination of selected cell populations in analytic cytology
US4661913A (en) * 1984-09-11 1987-04-28 Becton, Dickinson And Company Apparatus and method for the detection and classification of articles using flow cytometry techniques
US4727020A (en) * 1985-02-25 1988-02-23 Becton, Dickinson And Company Method for analysis of subpopulations of blood cells
NL8601000A (nl) * 1986-04-21 1987-11-16 Jan Greve T H Twente Afdeling Het gebruik van gepolariseerd licht in stromingscytometrie.
US4745285A (en) * 1986-08-21 1988-05-17 Becton Dickinson And Company Multi-color fluorescence analysis with single wavelength excitation
US4704891A (en) * 1986-08-29 1987-11-10 Becton, Dickinson And Company Method and materials for calibrating flow cytometers and other analysis instruments
US4805225A (en) * 1986-11-06 1989-02-14 The Research Foundation Of The State University Of New York Pattern recognition method and apparatus
US5041733A (en) * 1987-03-20 1991-08-20 Agency Of Industrial Science & Technology Method and apparatus for identifying chromosomes or cells
US4987086A (en) * 1987-11-30 1991-01-22 Becton, Dickinson And Company Method for analysis of subpopulations of cells
US4965725B1 (en) * 1988-04-08 1996-05-07 Neuromedical Systems Inc Neural network based automated cytological specimen classification system and method
US5144224A (en) * 1991-04-01 1992-09-01 Larsen Lawrence E Millimeter wave flow cytometer
US5627040A (en) * 1991-08-28 1997-05-06 Becton Dickinson And Company Flow cytometric method for autoclustering cells

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