ES2099159T3 - Uso de derivados de lipasa estimulada por sales biliares humanas para la preparacion de medicamentos. - Google Patents

Uso de derivados de lipasa estimulada por sales biliares humanas para la preparacion de medicamentos.

Info

Publication number
ES2099159T3
ES2099159T3 ES91911030T ES91911030T ES2099159T3 ES 2099159 T3 ES2099159 T3 ES 2099159T3 ES 91911030 T ES91911030 T ES 91911030T ES 91911030 T ES91911030 T ES 91911030T ES 2099159 T3 ES2099159 T3 ES 2099159T3
Authority
ES
Spain
Prior art keywords
preparation
lipase
medicines
new
dna sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91911030T
Other languages
English (en)
Spanish (es)
Inventor
Gunnar Bjursell
Lars Blackberg
Peter Carlsson
Sven Enerback
Olle Hernell
Jeanette Nilsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Astra AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra AB filed Critical Astra AB
Application granted granted Critical
Publication of ES2099159T3 publication Critical patent/ES2099159T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/596—Mixtures of surface active compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ES91911030T 1990-06-01 1991-05-30 Uso de derivados de lipasa estimulada por sales biliares humanas para la preparacion de medicamentos. Expired - Lifetime ES2099159T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9001985A SE9001985D0 (sv) 1990-06-01 1990-06-01 New chemical products

Publications (1)

Publication Number Publication Date
ES2099159T3 true ES2099159T3 (es) 1997-05-16

Family

ID=20379662

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91911030T Expired - Lifetime ES2099159T3 (es) 1990-06-01 1991-05-30 Uso de derivados de lipasa estimulada por sales biliares humanas para la preparacion de medicamentos.

Country Status (44)

Country Link
EP (1) EP0535048B1 (enExample)
JP (1) JPH05507201A (enExample)
KR (1) KR100212411B1 (enExample)
CN (2) CN1075113C (enExample)
AP (1) AP207A (enExample)
AT (1) ATE151077T1 (enExample)
AU (1) AU651979B2 (enExample)
BG (1) BG61165B1 (enExample)
CA (1) CA2083396C (enExample)
CZ (1) CZ287470B6 (enExample)
DE (1) DE69125489T2 (enExample)
DK (1) DK0535048T3 (enExample)
DZ (1) DZ1503A1 (enExample)
EG (1) EG19937A (enExample)
ES (1) ES2099159T3 (enExample)
FI (1) FI114639B (enExample)
GR (1) GR3023618T3 (enExample)
HK (1) HK62497A (enExample)
HR (1) HRP920771B1 (enExample)
HU (1) HU215258B (enExample)
IE (1) IE911844A1 (enExample)
IL (1) IL98273A (enExample)
IS (1) IS1751B (enExample)
JO (1) JO1694B1 (enExample)
LT (1) LT4020B (enExample)
LV (1) LV10292B (enExample)
MA (1) MA22166A1 (enExample)
MY (1) MY111245A (enExample)
NO (1) NO322962B1 (enExample)
NZ (1) NZ238223A (enExample)
PH (1) PH30761A (enExample)
PL (1) PL166534B1 (enExample)
PT (1) PT97836B (enExample)
RO (1) RO114793B1 (enExample)
RU (1) RU2140983C1 (enExample)
SE (1) SE9001985D0 (enExample)
SG (1) SG48078A1 (enExample)
SK (1) SK281089B6 (enExample)
TN (1) TNSN91041A1 (enExample)
TW (1) TW221712B (enExample)
UA (1) UA39165C2 (enExample)
WO (1) WO1991018923A1 (enExample)
YU (1) YU49138B (enExample)
ZA (1) ZA913778B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616483A (en) * 1992-06-11 1997-04-01 Aktiebolaget Astra Genomic DNA sequences encoding human BSSL/CEL
SE9300686D0 (sv) 1993-03-01 1993-03-01 Astra Ab Novel polypeptides
IS4130A (is) * 1993-03-01 1994-09-02 Ab Astra Ný fjölpeptíð
FR2754827B1 (fr) * 1996-10-17 1998-12-24 Biocem Lipases pancreatiques et/ou colipases recombinantes et polypeptides dervies produits par les plantes, leurs procedes d'obtention et leurs utilisations
JP2000026311A (ja) * 1998-07-02 2000-01-25 Amano Pharmaceut Co Ltd 胃排出能亢進剤組成物
WO2007063405A2 (en) * 2005-12-01 2007-06-07 University Of Bergen Diagnosis and treatment of exocrine pancreatic dysfunction and diabetes using human cel gene
CA2995446C (en) 2010-04-23 2020-05-12 Synageva Biopharma Corp Lysosomal storage disease enzyme
RS53947B1 (sr) 2010-09-09 2015-08-31 Synageva Biopharma Corp. Primena lizozomalne kisele lipaze za lečenje nedostatka lizozomalne kisele lipaze kod pacijenata
CN103189070A (zh) 2010-10-21 2013-07-03 瑞典孤儿比奥维特鲁姆有限公司 增加人婴儿对不饱和脂肪酸之吸收的方法
EP2629790B1 (en) 2010-10-21 2016-08-24 Swedish Orphan Biovitrum AB (Publ) Method to increase the growth velocity of human infants
AR111597A1 (es) 2017-06-19 2019-07-31 Swedish Orpham Biovitrum Ab Publ Proteína de fusión con polipéptido de extensión de vida media
CN119506248A (zh) 2019-08-30 2025-02-25 雀巢产品有限公司 工程化脂肪酶变体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60501758A (ja) * 1983-07-01 1985-10-17 セルテク　リミテツド タンパク質、医薬構成物、遺伝子、ベクタ−宿主生物及びそれらの生産方法

Also Published As

Publication number Publication date
CA2083396A1 (en) 1991-12-02
CN1326782A (zh) 2001-12-19
HU9203774D0 (en) 1993-03-29
PT97836B (pt) 1998-11-30
LV10292B (en) 1995-08-20
AP9100270A0 (en) 1991-07-31
HRP920771B1 (en) 1999-10-31
HUT63184A (en) 1993-07-28
DK0535048T3 (da) 1997-09-29
FI925453L (fi) 1992-11-30
IE911844A1 (en) 1991-12-04
NO924528L (no) 1992-11-24
FI114639B (fi) 2004-11-30
LV10292A (lv) 1994-10-20
CN1064313A (zh) 1992-09-09
DZ1503A1 (fr) 2004-09-13
JO1694B1 (en) 1992-08-09
IL98273A (en) 2005-11-20
CN1075113C (zh) 2001-11-21
DE69125489D1 (de) 1997-05-07
AP207A (en) 1992-08-18
IS3710A7 (is) 1991-12-02
WO1991018923A1 (en) 1991-12-12
AU7964591A (en) 1991-12-31
GR3023618T3 (en) 1997-08-29
CZ164491A3 (cs) 1999-07-14
IL98273A0 (en) 1992-06-21
RO114793B1 (ro) 1999-07-30
PT97836A (pt) 1992-02-28
NZ238223A (en) 1993-05-26
HU215258B (hu) 1998-11-30
PH30761A (en) 1997-10-17
LTIP1736A (en) 1995-08-25
SK281089B6 (sk) 2000-11-07
HK62497A (en) 1997-05-16
NO924528D0 (no) 1992-11-24
CZ287470B6 (cs) 2000-12-13
PL166534B1 (pl) 1995-05-31
MY111245A (en) 1999-10-30
JPH05507201A (ja) 1993-10-21
UA39165C2 (uk) 2001-06-15
CA2083396C (en) 2006-09-19
LT4020B (en) 1996-08-26
SK164491A3 (en) 1995-07-11
BG97123A (bg) 1993-12-24
AU651979B2 (en) 1994-08-11
IS1751B (is) 2000-07-21
NO322962B1 (no) 2006-12-18
TNSN91041A1 (fr) 1992-10-25
ZA913778B (en) 1992-02-26
TW221712B (enExample) 1994-03-11
FI925453A0 (fi) 1992-11-30
SE9001985D0 (sv) 1990-06-01
EP0535048B1 (en) 1997-04-02
EP0535048A1 (en) 1993-04-07
MA22166A1 (fr) 1991-12-31
BG61165B1 (bg) 1997-01-31
EG19937A (en) 2000-12-31
HRP920771A2 (en) 1997-04-30
DE69125489T2 (de) 1997-08-14
RU2140983C1 (ru) 1999-11-10
ATE151077T1 (de) 1997-04-15
YU95191A (sh) 1994-06-10
YU49138B (sh) 2004-03-12
KR100212411B1 (en) 1999-08-02
SG48078A1 (en) 1998-04-17

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