ES2173838T3 - Procedimiento para la preparacion fermentativa de l-aminoacidos utilizando bacterias corineformes. - Google Patents

Procedimiento para la preparacion fermentativa de l-aminoacidos utilizando bacterias corineformes.

Info

Publication number
ES2173838T3
ES2173838T3 ES00109843T ES00109843T ES2173838T3 ES 2173838 T3 ES2173838 T3 ES 2173838T3 ES 00109843 T ES00109843 T ES 00109843T ES 00109843 T ES00109843 T ES 00109843T ES 2173838 T3 ES2173838 T3 ES 2173838T3
Authority
ES
Spain
Prior art keywords
procedure
amino acids
fermentative preparation
bacteria
corineform bacteria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00109843T
Other languages
English (en)
Inventor
Yvonne Tilg
Bernhard Prof Dr Eikmanns
Lothar Dr Eggeling
Hermann Prof Dr Sahm
Bettina Dr Mockel
Walter Dr Pfefferle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forschungszentrum Juelich GmbH
Evonik Operations GmbH
Original Assignee
Forschungszentrum Juelich GmbH
Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forschungszentrum Juelich GmbH, Degussa GmbH filed Critical Forschungszentrum Juelich GmbH
Application granted granted Critical
Publication of ES2173838T3 publication Critical patent/ES2173838T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/20—Aspartic acid; Asparagine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedimiento para la preparación de Llisina mediante la fermentación de bacterias corineformes, caracterizado porque se utilizan bacterias en las cuales se eleva la actividad intracelular de la enzima de accBC, en particular se sobreexpresa la secuencia de nucleótidos que codfica el gen accBC o que lo porta.
ES00109843T 1999-05-27 2000-05-10 Procedimiento para la preparacion fermentativa de l-aminoacidos utilizando bacterias corineformes. Expired - Lifetime ES2173838T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19924364A DE19924364A1 (de) 1999-05-27 1999-05-27 Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien

Publications (1)

Publication Number Publication Date
ES2173838T3 true ES2173838T3 (es) 2002-11-01

Family

ID=7909395

Family Applications (1)

Application Number Title Priority Date Filing Date
ES00109843T Expired - Lifetime ES2173838T3 (es) 1999-05-27 2000-05-10 Procedimiento para la preparacion fermentativa de l-aminoacidos utilizando bacterias corineformes.

Country Status (15)

Country Link
US (1) US6379934B1 (es)
EP (1) EP1055730B1 (es)
JP (1) JP2000350580A (es)
KR (1) KR20010049405A (es)
CN (1) CN1275622A (es)
AT (1) ATE214736T1 (es)
AU (1) AU3644600A (es)
BR (1) BR0001906A (es)
CA (1) CA2309481A1 (es)
DE (2) DE19924364A1 (es)
ES (1) ES2173838T3 (es)
HU (1) HUP0002020A2 (es)
ID (1) ID26177A (es)
SK (1) SK7662000A3 (es)
ZA (1) ZA200002659B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1360298A2 (en) * 2001-02-16 2003-11-12 Degussa AG Nucleotide sequences of the ribosomal protein s12 gene (rpsl) from corynebacterium glutamicum
US7160711B2 (en) * 2001-08-06 2007-01-09 Degussa Ag Coryneform bacteria which produce chemical compounds I
US20060270013A1 (en) 2003-02-18 2006-11-30 Michel Chateau Method for the production of evolved microorganisms which permit the generation or modification of metabolic pathways
WO2005007862A2 (en) * 2003-07-08 2005-01-27 Novus Internation, Inc Methionine recovery processes
KR101167228B1 (ko) * 2004-06-10 2012-07-23 보드 오브 트러스티즈 오브 미시건 스테이트 유니버시티 라이신으로부터 카프로락탐의 합성
CN101541746B (zh) * 2007-02-20 2013-01-02 密执安州立大学董事会 用于生产己内酰胺的催化脱氨基
US20110190488A1 (en) * 2008-07-24 2011-08-04 Wicks Douglas A Methods of Making Cyclic Amide Monomers and Related Derivatives
US20110012309A1 (en) * 2009-07-15 2011-01-20 David Schreff Aerodynamic sports toy, game and method of play

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56160997A (en) 1980-05-16 1981-12-11 Ajinomoto Co Inc Preparation of l-lysine by fermenaition method
JPS58126789A (ja) * 1981-12-29 1983-07-28 Kyowa Hakko Kogyo Co Ltd レースレオニンの製造法
DE3823451C2 (de) 1988-07-11 1997-02-20 Forschungszentrum Juelich Gmbh Rekombinante DNA, damit transformierte Mikrooganismen und Verwendung dieser Mikroorganismen zur Herstellung von L-Lysin mit Hilfe dieser Mikroorganismen
GB2223754B (en) 1988-09-12 1992-07-22 Degussa Dna encoding phosphoenolpyruvate carboxylase
DE3908201A1 (de) 1989-03-14 1990-09-27 Degussa Verfahren zur fermentativen herstellung von l-lysin
DE3943117A1 (de) * 1989-12-27 1991-07-04 Forschungszentrum Juelich Gmbh Verfahren zur fermentativen herstellung von aminosaeure, insbesondere l-lysin, dafuer geeignete mikroorganismen und rekombinante dna

Also Published As

Publication number Publication date
CN1275622A (zh) 2000-12-06
DE19924364A1 (de) 2000-11-30
US6379934B1 (en) 2002-04-30
ZA200002659B (en) 2001-11-26
AU3644600A (en) 2000-11-30
SK7662000A3 (en) 2000-12-11
DE50000123D1 (de) 2002-04-25
EP1055730A1 (de) 2000-11-29
HU0002020D0 (en) 2000-08-28
KR20010049405A (ko) 2001-06-15
ID26177A (id) 2000-12-07
ATE214736T1 (de) 2002-04-15
EP1055730B1 (de) 2002-03-20
HUP0002020A2 (en) 2002-09-28
BR0001906A (pt) 2001-08-21
CA2309481A1 (en) 2000-11-27
JP2000350580A (ja) 2000-12-19

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