ES2089010T3 - Procedimiento para la obtencion de nucleosidos mediante la utilizacion de fosforilasas obtenibles a partir de bacillus stearothermophilus. - Google Patents
Procedimiento para la obtencion de nucleosidos mediante la utilizacion de fosforilasas obtenibles a partir de bacillus stearothermophilus.Info
- Publication number
- ES2089010T3 ES2089010T3 ES90903422T ES90903422T ES2089010T3 ES 2089010 T3 ES2089010 T3 ES 2089010T3 ES 90903422 T ES90903422 T ES 90903422T ES 90903422 T ES90903422 T ES 90903422T ES 2089010 T3 ES2089010 T3 ES 2089010T3
- Authority
- ES
- Spain
- Prior art keywords
- donor
- phosphorilases
- nucleosides
- obtainable
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/38—Nucleosides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/07—Bacillus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Abstract
ESTE INVENTO RELATA UN METODO DE PRODUCIR UN NUCLEOSIDO POR REACCIONAR UN DONADOR BASE, UN DONADOR DE RESIDUO DE AZUCAR, Y UN DONADOR FOSFATO CON OTRO EN LA PRESENCIA DE UNA PREPARACION ENZIMATICA QUE CONTIENE UNA FOSFORILASA NUCLEOSIDA PARA POR ELLO FORMAR UN ENLACE GLICOSIDO-N ENTRE UNA PARTE BASE DEL DONADOR DE BASE Y UNA PARTE DEL RESIDUO DE AZUCAR DEL DONADOR DE RESIDUO DE AZUCAR, CARACTERIZADO EN QUE DICHA PREPARACION ENZIMATICA QUE CONTIENE UNA FOSFORILASA NUCLEOSIDA ESTA BASADA EN LAS CELULAS DE AL MENOS UN MICROORGANISMO SELECCIONADO DE ENTRE ESOS QUE PERTENECEN A LA BACTERIA TERMOFILICA DEL BACILLUS GENUS, Y TENIENDO UNA ACTIVIDAD FOSFORILASA NUCLEOSIDA ALTA POR UNIDAD DE PESO DE LA CELULA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4878589 | 1989-02-28 | ||
JP20355689 | 1989-08-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2089010T3 true ES2089010T3 (es) | 1996-10-01 |
Family
ID=26389109
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90903422T Expired - Lifetime ES2089010T3 (es) | 1989-02-28 | 1990-02-27 | Procedimiento para la obtencion de nucleosidos mediante la utilizacion de fosforilasas obtenibles a partir de bacillus stearothermophilus. |
Country Status (11)
Country | Link |
---|---|
US (3) | US5258301A (es) |
EP (1) | EP0411158B1 (es) |
JP (1) | JP2795748B2 (es) |
KR (1) | KR970010134B1 (es) |
AT (1) | ATE138689T1 (es) |
AU (1) | AU631607B2 (es) |
CA (1) | CA2028119C (es) |
DE (1) | DE69027154T2 (es) |
DK (1) | DK0411158T3 (es) |
ES (1) | ES2089010T3 (es) |
WO (1) | WO1990010080A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR970010134B1 (ko) * | 1989-02-28 | 1997-06-21 | 야마사 쇼오유 가부시끼가이샤 | 뉴클레오시드의 제조법 |
RS49561B (sr) * | 1993-12-14 | 2007-04-10 | Galenika A.D., | Postupak za enzimsku sintezu triazolo nukleozida primenom termofilnih bakterija |
US5547857A (en) * | 1994-04-18 | 1996-08-20 | Ajinomoto Co., Inc. | Process for producing 5-methyluridine and purification by sedimentation velocity |
US6316228B1 (en) * | 1996-10-21 | 2001-11-13 | The University Of Iowa Research Foundation | Efficient synthesis of nucleosides |
JP3864357B2 (ja) * | 1997-08-04 | 2006-12-27 | 有機合成薬品工業株式会社 | プリンヌクレオシド化合物の製造方法 |
JP3799784B2 (ja) * | 1997-11-14 | 2006-07-19 | 味の素株式会社 | 2,6−ジアミノプリン−2’−デオキシリボシドおよび2’−デオキシグアノシンの製造法 |
AU6571700A (en) * | 1999-08-20 | 2001-03-19 | Institut Pasteur | Enzymatic synthesis of deoxyribonucleosides |
JP4066121B2 (ja) * | 2000-03-27 | 2008-03-26 | 有機合成薬品工業株式会社 | グアノシン類及びその中間体の製造方法 |
CA2380804A1 (en) * | 2001-05-01 | 2002-11-01 | Mitsui Chemicals, Inc. | Method for producing cytosine nucleosides compounds |
KR101818564B1 (ko) * | 2016-03-21 | 2018-01-15 | 에스티팜 주식회사 | 바실러스 유래 뉴클레오시드 포스포릴라아제 및 락토코쿠스 유래 아데노신 디아미나아제를 이용한 3'-아미노-2',3'-디데옥시구아노신의 제조 방법 |
KR101818561B1 (ko) * | 2016-03-21 | 2018-01-15 | 에스티팜 주식회사 | 바실러스 유래 뉴클레오시드 포스포릴라아제를 이용한 3'-아미노-2',3'-디데옥시아데노신의 제조 방법 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56148289A (en) * | 1980-04-18 | 1981-11-17 | Unitika Ltd | Preparation of heat-resistant polynucleotide phosphorylase |
CA1156573A (en) * | 1980-04-18 | 1983-11-08 | Hiroshi Nakajima | Strain uk 788 and process for producing a useful enzyme |
JPS57146593A (en) * | 1981-03-09 | 1982-09-10 | Ajinomoto Co Inc | Preparation of ribofuranosyltriazole derivative |
JPS58170493A (ja) * | 1982-04-01 | 1983-10-07 | Yamasa Shoyu Co Ltd | 3′−デオキシグアノシンの製造法 |
US4614719A (en) * | 1982-04-30 | 1986-09-30 | Yamasa Shoyu Kabushiki Kaisha | Process for producing ribavirin |
JP2547438B2 (ja) * | 1988-06-22 | 1996-10-23 | 日本たばこ産業株式会社 | ヌクレオシド化合物の製造方法 |
KR970010134B1 (ko) * | 1989-02-28 | 1997-06-21 | 야마사 쇼오유 가부시끼가이샤 | 뉴클레오시드의 제조법 |
JP3080771B2 (ja) * | 1992-04-17 | 2000-08-28 | ユニチカ株式会社 | ジヌクレオシドポリリン酸又はその誘導体の製造方法 |
-
1990
- 1990-02-27 KR KR1019900702343A patent/KR970010134B1/ko not_active IP Right Cessation
- 1990-02-27 WO PCT/JP1990/000240 patent/WO1990010080A1/ja active IP Right Grant
- 1990-02-27 JP JP2503654A patent/JP2795748B2/ja not_active Expired - Fee Related
- 1990-02-27 US US07/602,221 patent/US5258301A/en not_active Expired - Lifetime
- 1990-02-27 CA CA002028119A patent/CA2028119C/en not_active Expired - Lifetime
- 1990-02-27 DE DE69027154T patent/DE69027154T2/de not_active Expired - Lifetime
- 1990-02-27 AT AT90903422T patent/ATE138689T1/de active
- 1990-02-27 DK DK90903422.5T patent/DK0411158T3/da active
- 1990-02-27 ES ES90903422T patent/ES2089010T3/es not_active Expired - Lifetime
- 1990-02-27 AU AU51080/90A patent/AU631607B2/en not_active Ceased
- 1990-02-27 EP EP90903422A patent/EP0411158B1/en not_active Expired - Lifetime
-
1993
- 1993-05-04 US US08/056,745 patent/US5384251A/en not_active Expired - Lifetime
-
1994
- 1994-10-07 US US08/319,574 patent/US5506122A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0411158A4 (en) | 1992-03-11 |
CA2028119C (en) | 2000-05-16 |
EP0411158A1 (en) | 1991-02-06 |
CA2028119A1 (en) | 1990-08-29 |
AU5108090A (en) | 1990-09-26 |
AU631607B2 (en) | 1992-12-03 |
EP0411158B1 (en) | 1996-05-29 |
KR920700290A (ko) | 1992-02-19 |
DE69027154T2 (de) | 1996-10-24 |
US5258301A (en) | 1993-11-02 |
US5506122A (en) | 1996-04-09 |
DK0411158T3 (da) | 1996-06-17 |
US5384251A (en) | 1995-01-24 |
KR970010134B1 (ko) | 1997-06-21 |
DE69027154D1 (de) | 1996-07-04 |
WO1990010080A1 (en) | 1990-09-07 |
ATE138689T1 (de) | 1996-06-15 |
JP2795748B2 (ja) | 1998-09-10 |
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