ES2085316T3 - Comprimidos con liberacion de velocidad controlada de substancias activas. - Google Patents

Comprimidos con liberacion de velocidad controlada de substancias activas.

Info

Publication number
ES2085316T3
ES2085316T3 ES90123091T ES90123091T ES2085316T3 ES 2085316 T3 ES2085316 T3 ES 2085316T3 ES 90123091 T ES90123091 T ES 90123091T ES 90123091 T ES90123091 T ES 90123091T ES 2085316 T3 ES2085316 T3 ES 2085316T3
Authority
ES
Spain
Prior art keywords
substances
tablets
active substances
aqueous
controlled speed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90123091T
Other languages
English (en)
Inventor
Ubaldo Conte
Manna Aldo La
Paolo Colombo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jagotec AG
Original Assignee
Jagotec AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11199332&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2085316(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Jagotec AG filed Critical Jagotec AG
Application granted granted Critical
Publication of ES2085316T3 publication Critical patent/ES2085316T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Abstract

TABLETAS CON LIBERACION CONTROLADA DE LAS SUSTANCIAS ACTIVAS, QUE CONSTAN DE UN NUCLEO DE FORMA GEOMETRICA DEFINIDA QUE CONTIENE LA SUSTANCIA ACTIVA, SUSTANCIAS DE POLIMERO QUE SE HINCHAN AL CONTACTO CON LIQUIDOS ACUOSOS Y SUSTANCIAS DE POLIMERO CON PROPIEDADES AGLUTINANTES, Y UN SOPORTE APLICADO A DICHO NUCLEO PARA CUBRIR PARCIALMENTE SU SUPERFICIE, CONSTANDO EL SOPORTE DE SUSTANCIAS DE POLIMERO QUE SON SOLUBLES DE FORMA LENTA Y/O AGLUTINANTES DE FORMA LENTA EN LIQUIDOS ACUOSOS, SUSTANCIAS PLASTIFICANTES, Y POSIBLEMENTE SUSTANCIAS CON UNA FUNCION AUXILIAR
ES90123091T 1989-12-14 1990-12-03 Comprimidos con liberacion de velocidad controlada de substancias activas. Expired - Lifetime ES2085316T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02269489A IT1237904B (it) 1989-12-14 1989-12-14 Compresse a rilascio a velocita' controllata delle sostanze attive

Publications (1)

Publication Number Publication Date
ES2085316T3 true ES2085316T3 (es) 1996-06-01

Family

ID=11199332

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90123091T Expired - Lifetime ES2085316T3 (es) 1989-12-14 1990-12-03 Comprimidos con liberacion de velocidad controlada de substancias activas.

Country Status (10)

Country Link
US (1) US5422123A (es)
EP (1) EP0432607B1 (es)
JP (1) JP2907557B2 (es)
AT (1) ATE135906T1 (es)
CA (1) CA2031393C (es)
DE (1) DE69026215T2 (es)
DK (1) DK0432607T3 (es)
ES (1) ES2085316T3 (es)
GR (1) GR3020404T3 (es)
IT (1) IT1237904B (es)

Families Citing this family (146)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2572673B2 (ja) * 1990-07-25 1997-01-16 エスエス製薬株式会社 徐放性錠剤
IT1255522B (it) * 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
IT1256393B (it) * 1992-11-17 1995-12-04 Inverni Della Beffa Spa Forme matriciali multistrato per il rilascio controllato di principi attivi
US6183778B1 (en) 1993-09-21 2001-02-06 Jagotec Ag Pharmaceutical tablet capable of liberating one or more drugs at different release rates
IT1265240B1 (it) * 1993-11-30 1996-10-31 Ekita Investments Nv Compressa farmaceutica a rilascio controllato, di forma lenticolare
DE4341442C2 (de) * 1993-12-04 1998-11-05 Lohmann Therapie Syst Lts Vorrichtung zur kontrollierten Freisetzung von Wirkstoffen sowie ihre Verwendung
US6787156B1 (en) * 1994-02-23 2004-09-07 Bm Research A/S Controlled release composition
DE4416926C2 (de) * 1994-05-13 2000-01-13 Lohmann Therapie Syst Lts Verfahren zur Herstellung von Vorrichtungen zur kontrollierten Freisetzung von Wirkstoffen
US5583162A (en) * 1994-06-06 1996-12-10 Biopore Corporation Polymeric microbeads and method of preparation
DE4431653C2 (de) 1994-09-06 2000-01-20 Lohmann Therapie Syst Lts Manteltablette zur kontrollierten Freisetzung von Wirkstoffen, ein Verfahren zu ihrer Herstellung und ihre Verwendung
US5534263A (en) 1995-02-24 1996-07-09 Alza Corporation Active agent dosage form comprising a matrix and at least two insoluble bands
US6548084B2 (en) 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
GB9514842D0 (en) * 1995-07-20 1995-09-20 Smithkline Beecham Plc Novel formulation
CA2182851A1 (en) * 1995-08-15 1997-02-16 August Masaru Watanabe Method for treating substance abuse withdrawal
US5783212A (en) * 1996-02-02 1998-07-21 Temple University--of the Commonwealth System of Higher Education Controlled release drug delivery system
IT1282650B1 (it) * 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
US5830503A (en) * 1996-06-21 1998-11-03 Andrx Pharmaceuticals, Inc. Enteric coated diltiazem once-a-day formulation
AU724490B2 (en) * 1996-08-29 2000-09-21 Jagotec Ag Tablet with controlled release of alfuzosin hydrochloride
DE19640062B4 (de) 1996-09-28 2006-04-27 Lts Lohmann Therapie-Systeme Ag Orale Zubereitung, enthaltend in einer in wässrigem Medium quellbaren Matrix wenigstens einen pharmazeutischen Wirkstoff
EP0954291B1 (en) * 1996-10-25 2005-12-28 Shire Laboratories Inc. Soluble form osmotic dose delivery system
US6361796B1 (en) 1996-10-25 2002-03-26 Shire Laboratories, Inc. Soluble form osmotic dose delivery system
AU7888298A (en) * 1997-01-03 1998-07-31 Elan Corporation, Plc Sustained release cisapride minitablet formulation
US6074669A (en) * 1997-01-20 2000-06-13 Ranbaxy Laboratories Limited Controlled drug delivery system for diltiazem
US6048908A (en) 1997-06-27 2000-04-11 Biopore Corporation Hydrophilic polymeric material
IT1294760B1 (it) 1997-09-03 1999-04-12 Jagotec Ag Procedimento per la preparazione di compresse farmaceutiche in grado di cedere,secondo schemi predeterminabili, principi attivi poco
ATE267589T1 (de) * 1998-04-03 2004-06-15 Egalet As Zusammensetzung mit kontrollierter wirkstoff- freisetzung
US6365183B1 (en) 1998-05-07 2002-04-02 Alza Corporation Method of fabricating a banded prolonged release active agent dosage form
US6524620B2 (en) 1998-07-20 2003-02-25 Andrx Pharmaceuticals, Inc. Diltiazem controlled release formulation and method of manufacture
ATE340563T1 (de) * 2000-02-04 2006-10-15 Depomed Inc DOSIERUNGSFORM DES TYPS ßHÜLLE UND KERNß MIT EINER WIRKSTOFFFREISETZUNG, DIE SICH DER NULLTEN ORDNUNG ANNÄHERT
AR030557A1 (es) 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
US6720003B2 (en) 2001-02-16 2004-04-13 Andrx Corporation Serotonin reuptake inhibitor formulations
US6960357B2 (en) * 2001-05-25 2005-11-01 Mistral Pharma Inc. Chemical delivery device
IL159715A0 (en) * 2001-07-10 2004-06-20 Teva Pharma Drug delivery system for zero order, zero order-biphasic, ascending or descending drug delivery
GB0117619D0 (en) * 2001-07-19 2001-09-12 Phoqus Ltd Pharmaceutical dosage form
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
US20040253310A1 (en) 2001-09-21 2004-12-16 Gina Fischer Morphine polymer release system
EP2957281A1 (en) 2001-09-21 2015-12-23 Egalet Ltd. Polymer release system
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
CA2409552A1 (en) 2001-10-25 2003-04-25 Depomed, Inc. Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US20030152622A1 (en) * 2001-10-25 2003-08-14 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral diuretic
US20030104052A1 (en) * 2001-10-25 2003-06-05 Bret Berner Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US6602911B2 (en) * 2001-11-05 2003-08-05 Cypress Bioscience, Inc. Methods of treating fibromyalgia
US6635675B2 (en) 2001-11-05 2003-10-21 Cypress Bioscience, Inc. Method of treating chronic fatigue syndrome
ITMI20012481A1 (it) * 2001-11-23 2003-05-23 Univ Parma Sistemi modulari per il rilascio controllato di sostanza a controllo spaziale e temporale
NZ534104A (en) * 2001-12-24 2007-03-30 Teva Pharma Dosage form with a core tablet of active ingredient sheathed in a compressed annular body of powder or granular material
US20040052843A1 (en) * 2001-12-24 2004-03-18 Lerner E. Itzhak Controlled release dosage forms
EP2316468A1 (en) 2002-02-22 2011-05-04 Shire LLC Delivery system and methods for protecting and administering dextroamphetamine
ITMI20020514A1 (it) * 2002-03-12 2003-09-12 Jagotec Ag Sistema terapeutico per il rilascio controllato di uno o piu' principi attivi
US7008979B2 (en) * 2002-04-30 2006-03-07 Hydromer, Inc. Coating composition for multiple hydrophilic applications
WO2004041252A1 (en) * 2002-11-08 2004-05-21 Egalet A/S Controlled release carvedilol compositions
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
JP3811127B2 (ja) * 2003-01-30 2006-08-16 株式会社東芝 情報記録装置及び情報記録方法
US20040185093A1 (en) * 2003-03-18 2004-09-23 Szymczak Christopher E. Compositions containing sucralose
WO2004084868A1 (en) 2003-03-26 2004-10-07 Egalet A/S Morphine controlled release system
DE602004014747D1 (de) * 2003-03-26 2008-08-14 Egalet As Matrixzubereitungen für die kontrollierte darreichung von arzneistoffen
GB0319874D0 (en) * 2003-08-22 2003-09-24 Glaxo Group Ltd Novel formulation
US7611728B2 (en) * 2003-09-05 2009-11-03 Supernus Pharmaceuticals, Inc. Osmotic delivery of therapeutic compounds by solubility enhancement
US10226428B2 (en) 2003-09-19 2019-03-12 Sun Pharma Advanced Research Company Ltd. Oral drug delivery system
CN1856299B (zh) * 2003-09-19 2013-09-04 太阳医药工业有限公司 口服药物释出系统
US10213387B2 (en) 2003-09-19 2019-02-26 Sun Pharma Advanced Research Company Ltd. Oral drug delivery system
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
US20050266082A1 (en) * 2004-05-26 2005-12-01 Patel Satishkumar A Preparation of stable paroxetine HC1 ER tablets using a melt granulation process
US20060002986A1 (en) * 2004-06-09 2006-01-05 Smithkline Beecham Corporation Pharmaceutical product
EP1765292B1 (en) 2004-06-12 2017-10-04 Collegium Pharmaceutical, Inc. Abuse-deterrent drug formulations
WO2006010640A1 (en) * 2004-07-29 2006-02-02 Sanofi-Aventis Pharmaceutical multilayer tablet for controlled release of active ingredients with highly ph-dependent solubility
EP1791531A1 (en) * 2004-08-20 2007-06-06 Alpharma, Inc. Paroxetine formulations
KR100635301B1 (ko) * 2004-09-15 2006-10-17 지엘팜텍 주식회사 메실산 독사조신을 함유하는 서방성 정제
US20060062811A1 (en) * 2004-09-21 2006-03-23 Szymczak Christopher E Medicinal cooling emulsions
US8779175B2 (en) 2004-10-25 2014-07-15 Synthonics, Inc. Coordination complexes, pharmaceutical solutions comprising coordination complexes, and methods of treating patients
EP2343057A1 (en) 2004-11-23 2011-07-13 Neuromolecular Pharmaceuticals, Inc Method and composition for administering an NMDA receptor antagonist to a subject
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
EP2623099A1 (en) 2004-11-24 2013-08-07 Neuromolecular Pharmaceuticals, Inc Composition and method for treating neurological disease
AR053986A1 (es) 2004-12-03 2007-05-30 Osmotica Pharmaceutical Argent Dispositivo osmotico que contiene amantadina y una sal osmotica
KR101406456B1 (ko) 2005-04-06 2014-06-20 아다마스 파마슈티칼스, 인코포레이티드 Ｃｎｓ 장애의 치료를 위한 방법 및 조성물
BRPI0611272A2 (pt) * 2005-05-03 2011-11-16 Mutual Pharmaceutical Co formulações de quinina
JP2008542394A (ja) * 2005-06-02 2008-11-27 バイオベイル・ラボラトリーズ・インターナショナル・ソサイアティーズ・ウィズ・リストリクティッド・ライアビリティ 少なくとも１つの形態のベンラファキシンの調節放出性組成物
WO2006128471A2 (en) * 2005-06-03 2006-12-07 Egalet A/S A solid pharmaceutical composition with a first fraction of a dispersion medium and a second fraction of a matrix, the latter being at least partially first exposed to gastrointestinal fluids
WO2007008305A1 (en) * 2005-07-08 2007-01-18 Cherng-Ju Kim Asymmetrically coated tablet
US20070036859A1 (en) * 2005-08-11 2007-02-15 Perry Ronald L Sustained release antihistamine and decongestant composition
US8778395B2 (en) * 2005-08-11 2014-07-15 Andrx Labs, Llc Diltiazem controlled release formulation and method of manufacture
WO2007035816A2 (en) * 2005-09-20 2007-03-29 Dr. Reddy's Laboratories Ltd. Paroxetine compositions
US7994220B2 (en) * 2005-09-28 2011-08-09 Cypress Bioscience, Inc. Milnacipran for the long-term treatment of fibromyalgia syndrome
US20070112031A1 (en) * 2005-11-14 2007-05-17 Gant Thomas G Substituted phenylpiperidines with serotoninergic activity and enhanced therapeutic properties
KR100591142B1 (ko) * 2005-11-04 2006-06-20 지엘팜텍 주식회사 파록세틴을 활성물질로 함유하는 장용성 서방형 정제
WO2007059372A2 (en) * 2005-11-09 2007-05-24 St. Jude Children's Research Hospital Use of chloroquine to treat metabolic syndrome
US8691272B2 (en) * 2005-12-30 2014-04-08 Intelgenx Corp. Multilayer tablet
US20070172509A1 (en) * 2006-01-24 2007-07-26 Conor Medsystems, Inc. Drug Delivery System for Retarding Release of Water Soluble Drugs
US8747897B2 (en) 2006-04-27 2014-06-10 Supernus Pharmaceuticals, Inc. Osmotic drug delivery system
US8765178B2 (en) * 2006-07-19 2014-07-01 Watson Laboratories, Inc. Controlled release formulations and associated methods
ES2547226T5 (es) 2006-08-30 2020-06-12 Jagotec Ag Formulaciones de dosificación oral de liberación controlada que comprenden un núcleo y una o más capas de barrera
US8124598B2 (en) * 2006-09-14 2012-02-28 Sharon Sageman 7-keto DHEA for psychiatric use
US20080181947A1 (en) * 2006-09-26 2008-07-31 Astellas Pharma Inc. Controlled release dosage form of tacrolimus
US20090028935A1 (en) * 2006-12-01 2009-01-29 Kristin Arnold Carvedilol forms, compositions, and methods of preparation thereof
WO2008070072A2 (en) * 2006-12-01 2008-06-12 Mutual Pharmaceutical Company, Inc. Carvedilol forms, compositions, and methods of preparation thereof
WO2008084698A1 (ja) * 2006-12-28 2008-07-17 Astellas Pharma Inc. タクロリムス徐放性医薬組成物
CA2674536C (en) * 2007-01-16 2016-07-26 Egalet A/S Use of i) a polyglycol and ii) an active drug substance for the preparation of a pharmaceutical composition for i) mitigating the risk of alcohol induced dose dumping and/or ii) reducing the risk of drug abuse
KR100885029B1 (ko) 2007-02-07 2009-02-23 지엘팜텍 주식회사 경구투여용 서방성 삼중정제
EP2155167A2 (en) 2007-06-04 2010-02-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
US20100160274A1 (en) * 2007-09-07 2010-06-24 Sharon Sageman 7-KETO DHEA for Psychiatric Use
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine
KR20100136967A (ko) * 2008-02-15 2010-12-29 썬 파마 어드밴스트 리서치 컴패니 리미티드 파열 효과가 감소된 방출 제어 경구 정제
WO2009146537A1 (en) * 2008-06-02 2009-12-10 Pharmascience Inc. Multilayer control-release drug delivery system
AU2009279372A1 (en) 2008-08-06 2010-02-11 Gosforth Centre (Holdings) Pty Ltd Compositions and methods for treating psychiatric disorders
CA2738414C (en) 2008-09-29 2014-05-27 Wockhardt Research Centre Extended release dosage form of ropinirole
US20100233259A1 (en) * 2008-12-12 2010-09-16 Pascal Grenier Dosage form of ropinirole
US20100151020A1 (en) * 2008-12-16 2010-06-17 Vered Rosenberger Drug delivery system for zero order, zero order biphasic, ascending or descending drug delivery of methylphenidate
EP2393484A1 (en) 2009-02-06 2011-12-14 Egalet Ltd. Immediate release composition resistant to abuse by intake of alcohol
US8945622B2 (en) 2009-03-09 2015-02-03 Council Of Scientific And Industrial Research Sustained release composition of therapeutic agent
US20100247646A1 (en) * 2009-03-26 2010-09-30 Ranbaxy Laboratories Limited Extended release tablets of nisoldipine
AU2010265213B2 (en) 2009-06-24 2012-08-23 Egalet Ltd. Controlled release formulations
AU2010325960C1 (en) 2009-12-02 2015-08-06 Adamas Pharma, Llc Amantadine compositions and methods of use
US20110136815A1 (en) 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
US20110150986A1 (en) * 2009-12-18 2011-06-23 Kristin Arnold Quinine formulations, method of making, and metho of use thereof
US10485770B2 (en) 2009-12-21 2019-11-26 Aptapharma, Inc. Functionally-coated multilayer tablets
WO2011080716A2 (en) 2010-01-04 2011-07-07 Wockhardt Limited Pharmaceutical composition for modified delivery of actives
JP5849947B2 (ja) 2010-03-29 2016-02-03 アステラス製薬株式会社 放出制御医薬組成物
CN108186611A (zh) 2010-04-30 2018-06-22 帝国制药美国公司 丙炔基氨基茚满透皮组合物
ES2643291T3 (es) 2010-12-22 2017-11-22 Purdue Pharma L.P. Formas de dosificación de liberación controlada con cierre inviolable recubiertas
EP2654733B1 (en) 2010-12-23 2016-04-06 Purdue Pharma LP Tamper resistant solid oral dosage forms
CN102525988B (zh) * 2011-01-04 2016-01-06 北京天衡药物研究院 富马酸喹硫平缓释片
KR20140045925A (ko) 2011-03-17 2014-04-17 루핀 리미티드 선택적 세로토닌 재흡수 억제제의 방출조절형 약제학적 조성물
US9119799B2 (en) 2011-03-24 2015-09-01 Teikoku Pharma Usa, Inc. Transdermal compositions comprising an active agent layer and an active agent conversion layer
GB201111712D0 (en) 2011-07-08 2011-08-24 Gosforth Ct Holdings Pty Ltd Pharmaceutical compositions
US9913812B2 (en) 2011-11-09 2018-03-13 Teikoku Pharma Usa, Inc. Methods for the treatment of skin neoplasms
US20150086587A1 (en) * 2012-03-28 2015-03-26 Kansas State University Research Foundation Vaccine adjuvant
CN103371982A (zh) * 2012-04-20 2013-10-30 王进京 盐酸帕罗西汀肠溶控释片新型处方组成及制备方法
KR20150059167A (ko) 2012-07-06 2015-05-29 에갈렛 리미티드 제어된 방출을 위한 남용 제지 약학적 조성물
US10918607B2 (en) 2012-11-02 2021-02-16 Teikoku Pharma Usa, Inc. Propynylaminoindan transdermal compositions
WO2014086358A1 (en) * 2012-12-07 2014-06-12 Gumlink A/S Compressed tablets
CN102961354A (zh) * 2012-12-24 2013-03-13 中国药科大学 阿西美辛三层控释片及其制备方法
MX2015010041A (es) 2013-02-05 2015-10-30 Purdue Pharma Lp Formulacion farmaceuticas resistentes a la alteracion.
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
WO2014204933A1 (en) 2013-06-17 2014-12-24 Adamas Pharmaceuticals, Inc. Amantadine compositions and methods of use
WO2015073736A1 (en) 2013-11-13 2015-05-21 Arbor Pharmaceuticals, Llc Methods and compositions for treating adhd
US9132096B1 (en) 2014-09-12 2015-09-15 Alkermes Pharma Ireland Limited Abuse resistant pharmaceutical compositions
WO2016132217A1 (en) 2015-02-20 2016-08-25 Osmotica Kereskedelmi Es Szolgaltato Kft Method of improving gaba-b receptor agonist therapy
CN104622830A (zh) * 2015-03-04 2015-05-20 潍坊高新生物园发展有限公司 一种盐酸文拉法辛多层骨架控释片制剂及其制备方法
AU2016288643A1 (en) 2015-07-02 2018-02-22 University Of Louisville Research Foundation, Inc. Edible plant-derived microvesicle compositions for delivery of miRNA and methods for treatment of cancer
WO2017117569A1 (en) 2015-12-30 2017-07-06 Adamas Pharmaceuticals, Inc. Methods and compositions for the treatment of seizure-related disorders
CN105832689A (zh) * 2016-04-26 2016-08-10 海南华益泰康药业有限公司 一种含有双层片芯的缓释片剂
US9737530B1 (en) 2016-06-23 2017-08-22 Collegium Pharmaceutical, Inc. Process of making stable abuse-deterrent oral formulations
WO2018200885A1 (en) 2017-04-26 2018-11-01 Neurocentria, Inc. Magnesium compositions and methods of use
CN115400092A (zh) * 2021-05-28 2022-11-29 上海博志研新药物技术有限公司 硝苯地平美托洛尔缓释组合物、其制备方法及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4218433A (en) * 1977-03-03 1980-08-19 Nippon Kayaku Kabushiki Kaisha Constant-rate eluting tablet and method of producing same
US4892742A (en) * 1985-11-18 1990-01-09 Hoffmann-La Roche Inc. Controlled release compositions with zero order release
IT1188212B (it) * 1985-12-20 1988-01-07 Paolo Colombo Sistema per il rilascio a velocita' controllata di sostanze attive
IT1201136B (it) * 1987-01-13 1989-01-27 Resa Farma Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive
NO883326L (no) * 1987-08-11 1989-02-13 Bayer Ag Dhp-retard-tilberedning.

Also Published As

Publication number Publication date
DK0432607T3 (da) 1996-04-29
DE69026215D1 (de) 1996-05-02
ATE135906T1 (de) 1996-04-15
CA2031393A1 (en) 1991-06-15
EP0432607B1 (en) 1996-03-27
GR3020404T3 (en) 1996-09-30
IT8922694A0 (it) 1989-12-14
JP2907557B2 (ja) 1999-06-21
EP0432607A1 (en) 1991-06-19
US5422123A (en) 1995-06-06
IT1237904B (it) 1993-06-18
CA2031393C (en) 1998-12-15
DE69026215T2 (de) 1996-08-22
JPH06172162A (ja) 1994-06-21

Similar Documents

Publication Publication Date Title
ES2085316T3 (es) Comprimidos con liberacion de velocidad controlada de substancias activas.
DE68904461T2 (de) Absorbierende produkte die sich unter druck ausdehnende hydrogelstoffe enthalten.
ES243945Y (es) Una compresa absorbente para uso en contacto con la piel.
ES264967Y (es) "un dispositivo de soporte de articulos para uso sobre una superficie de un vehiculo automovil, dispuesta generalmente en posicion horizontal".
SE8605383D0 (sv) Flerfaldigt indelade transdermala och dermala plaster
NL178887C (nl) Werkwijze voor het stabiliseren van organisch materiaal alsmede gevormd voortbrengsel, vervaardigd onder toepassing van aldus gestabiliseerd materiaal.
NL7412236A (nl) Werkwijze en middel voor het verlagen van de ntratie van de werkzame stoffen in een tisch preparaat.
DK579387A (da) Middel til anvendelse i polymerer
NL7903578A (nl) Inrichting voor de bepaling van de ruimtelijke absorp- tieverdeling in een vlak onderzoeksgebied.
ES497804A0 (es) Procedimiento para detectar sustancias peroxidativamente activas en una muestra.
NL7700099A (nl) Werkwijze en inrichting voor het in een vlak en dun materiaal met een vezelstruktuur aan- brengen van rillijnen.
NL7701469A (nl) Werkwijze voor het bereiden van een geneesmiddel met hypolipidemische werking en werkwijze voor het bereiden van de in dit middel toegepaste werkzame verbindingen.
NL155045B (nl) Werkwijze voor het bereiden van organosiliciumpreparaten en de onder toepassing van deze preparaten van een antiadhesielaag voorziene voorwerpen.
NL185458C (nl) Werkwijze voor het bereiden van een petroleumhars en gebruik daarvan als kleverig makend middel.
NL190663B (nl) Werkwijze voor de bereiding van acrylonitril en werkwijze voor de bereiding van de daarbij toe te passen katalysator.
NO891112L (no) Artikkel til benyttelse innen protetisk teknikk.
IT8019740A0 (it) Derivati benzoazepinici.
NL7701774A (nl) Werkwijze voor het bereiden van vrijwel kleurloos, transparant glaskeramisch materiaal.
NL7701341A (nl) Punt matrix drukinrichting, alsmede werkwijze voor het drukken onder toepassing van zulk een inrichting.
NL7706618A (nl) Werkwijze voor het bekleden van een oppervlak van een drager en voorwerpen, vervaardigd onder toepassing van deze werkwijze.
NL7611124A (nl) Materialen voor het versieren van vlakke vezelprodukten.
DE3880600D1 (de) Oberflaechenaktives polymer.
IT1227787B (it) Oxo isoindolinil derivati otticamente attivi.
IT7926117A0 (it) Procedimento per la realizzazione di corpi sagomati in materiale plastico.
NL7610467A (nl) Intrekinrichting voor veiligheidsgordels.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 432607

Country of ref document: ES