ES2051968T3 - Metodo para el tratamiento de enfermedad periodontal mediante la liberacion continua de un agente terapeutico a la bolsa periodontal; composicion de materia del mismo y aparato para su administracion. - Google Patents

Metodo para el tratamiento de enfermedad periodontal mediante la liberacion continua de un agente terapeutico a la bolsa periodontal; composicion de materia del mismo y aparato para su administracion.

Info

Publication number
ES2051968T3
ES2051968T3 ES89121886T ES89121886T ES2051968T3 ES 2051968 T3 ES2051968 T3 ES 2051968T3 ES 89121886 T ES89121886 T ES 89121886T ES 89121886 T ES89121886 T ES 89121886T ES 2051968 T3 ES2051968 T3 ES 2051968T3
Authority
ES
Spain
Prior art keywords
therapeutic agent
periodontal
administration
treatment
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89121886T
Other languages
English (en)
Inventor
Nancy Susan Brizzolara
Michael Gerard Lanzilotti
James Ronald Lawter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2051968T3 publication Critical patent/ES2051968T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPOSICIONES ORALES PARA LA ADMINISTRACION LOCAL DE UN AGENTE TERAPEUTICO A UNA BOLSA PERIODONTAL DE UN PACIENTE PARA ALIVIAR EL DOLOR DENTAL COMPRENDE UNA PLURALIDAD DE MICROPARTICULAS DISTINTAS, SECAS CADA UNA DE LAS CUALES COMPRENDE UNA CANTIDAD EFECTIVA DE AL MENOS UN AGENTE TERAPEUTICO DISPERSADO EN UNA MATRIZ QUE COMPRENDE UN POLIMERO BIOCOMPATIBLE Y BIODEGRADABLE. APARATO Y METODOS SON TAMBIEN PROVISTOS PARA LA DISPENSACION DE LAS MICROPARTICULAS SECAS A LA BOLSA PERIODONTAL POR LO QUE LLEGA A CONVERTIRSE PEGAJOSO Y ADHERIRSE AL TEJIDO EN CUESTION PARA INDUCIR BENEFICIOS TERAPEUTICOS LARGO TIEMPO.
ES89121886T 1988-12-22 1989-11-27 Metodo para el tratamiento de enfermedad periodontal mediante la liberacion continua de un agente terapeutico a la bolsa periodontal; composicion de materia del mismo y aparato para su administracion. Expired - Lifetime ES2051968T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28907688A 1988-12-22 1988-12-22

Publications (1)

Publication Number Publication Date
ES2051968T3 true ES2051968T3 (es) 1994-07-01

Family

ID=23109956

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89121886T Expired - Lifetime ES2051968T3 (es) 1988-12-22 1989-11-27 Metodo para el tratamiento de enfermedad periodontal mediante la liberacion continua de un agente terapeutico a la bolsa periodontal; composicion de materia del mismo y aparato para su administracion.

Country Status (16)

Country Link
US (1) US5366733A (es)
EP (1) EP0374531B1 (es)
JP (1) JP2901674B2 (es)
KR (2) KR0143912B1 (es)
AT (1) ATE105177T1 (es)
AU (1) AU635912B2 (es)
CA (1) CA2006105C (es)
DE (1) DE68915132T2 (es)
DK (1) DK174915B1 (es)
ES (1) ES2051968T3 (es)
IE (1) IE63952B1 (es)
IL (1) IL92700A (es)
NO (1) NO178605C (es)
NZ (1) NZ231791A (es)
PT (1) PT92614B (es)
ZA (1) ZA899857B (es)

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US5942496A (en) 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US6074840A (en) 1994-02-18 2000-06-13 The Regents Of The University Of Michigan Recombinant production of latent TGF-beta binding protein-3 (LTBP-3)
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GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
MXPA00000009A (es) 1998-06-22 2005-09-08 Autologous Wound Therapy Inc Solicitud para patente de utilidad para curativo de heridas mejorado enriquecido con plaquetas.
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US20040142475A1 (en) * 2000-06-02 2004-07-22 Barman Shikha P. Delivery systems for bioactive agents
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US6576226B1 (en) * 2000-11-17 2003-06-10 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
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Also Published As

Publication number Publication date
DK655889A (da) 1990-06-23
AU4707789A (en) 1990-06-28
DE68915132T2 (de) 1994-12-08
JP2901674B2 (ja) 1999-06-07
NO895167L (no) 1990-06-25
IE894145L (en) 1990-06-22
ATE105177T1 (de) 1994-05-15
PT92614A (pt) 1990-06-29
EP0374531A3 (en) 1991-07-31
KR0143912B1 (ko) 1998-07-15
NZ231791A (en) 1992-05-26
EP0374531A2 (en) 1990-06-27
KR900009061A (ko) 1990-07-02
NO178605B (no) 1996-01-22
JPH02184620A (ja) 1990-07-19
EP0374531B1 (en) 1994-05-04
CA2006105A1 (en) 1990-06-22
ZA899857B (en) 1990-10-31
IL92700A0 (en) 1990-09-17
KR900009045A (ko) 1990-07-02
AU635912B2 (en) 1993-04-08
US5366733A (en) 1994-11-22
NO178605C (no) 1996-05-02
NO895167D0 (no) 1989-12-21
IL92700A (en) 1994-05-30
CA2006105C (en) 2000-03-14
PT92614B (pt) 1995-09-12
DE68915132D1 (de) 1994-06-09
DK174915B1 (da) 2004-02-23
DK655889D0 (da) 1989-12-21
KR0138651B1 (ko) 1998-05-15
IE63952B1 (en) 1995-06-28

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