ES2051968T3 - Metodo para el tratamiento de enfermedad periodontal mediante la liberacion continua de un agente terapeutico a la bolsa periodontal; composicion de materia del mismo y aparato para su administracion. - Google Patents

Metodo para el tratamiento de enfermedad periodontal mediante la liberacion continua de un agente terapeutico a la bolsa periodontal; composicion de materia del mismo y aparato para su administracion.

Info

Publication number
ES2051968T3
ES2051968T3 ES89121886T ES89121886T ES2051968T3 ES 2051968 T3 ES2051968 T3 ES 2051968T3 ES 89121886 T ES89121886 T ES 89121886T ES 89121886 T ES89121886 T ES 89121886T ES 2051968 T3 ES2051968 T3 ES 2051968T3
Authority
ES
Spain
Prior art keywords
therapeutic agent
periodontal
administration
treatment
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89121886T
Other languages
English (en)
Inventor
Nancy Susan Brizzolara
Michael Gerard Lanzilotti
James Ronald Lawter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of ES2051968T3 publication Critical patent/ES2051968T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

COMPOSICIONES ORALES PARA LA ADMINISTRACION LOCAL DE UN AGENTE TERAPEUTICO A UNA BOLSA PERIODONTAL DE UN PACIENTE PARA ALIVIAR EL DOLOR DENTAL COMPRENDE UNA PLURALIDAD DE MICROPARTICULAS DISTINTAS, SECAS CADA UNA DE LAS CUALES COMPRENDE UNA CANTIDAD EFECTIVA DE AL MENOS UN AGENTE TERAPEUTICO DISPERSADO EN UNA MATRIZ QUE COMPRENDE UN POLIMERO BIOCOMPATIBLE Y BIODEGRADABLE. APARATO Y METODOS SON TAMBIEN PROVISTOS PARA LA DISPENSACION DE LAS MICROPARTICULAS SECAS A LA BOLSA PERIODONTAL POR LO QUE LLEGA A CONVERTIRSE PEGAJOSO Y ADHERIRSE AL TEJIDO EN CUESTION PARA INDUCIR BENEFICIOS TERAPEUTICOS LARGO TIEMPO.
ES89121886T 1988-12-22 1989-11-27 Metodo para el tratamiento de enfermedad periodontal mediante la liberacion continua de un agente terapeutico a la bolsa periodontal; composicion de materia del mismo y aparato para su administracion. Expired - Lifetime ES2051968T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28907688A 1988-12-22 1988-12-22

Publications (1)

Publication Number Publication Date
ES2051968T3 true ES2051968T3 (es) 1994-07-01

Family

ID=23109956

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89121886T Expired - Lifetime ES2051968T3 (es) 1988-12-22 1989-11-27 Metodo para el tratamiento de enfermedad periodontal mediante la liberacion continua de un agente terapeutico a la bolsa periodontal; composicion de materia del mismo y aparato para su administracion.

Country Status (16)

Country Link
US (1) US5366733A (es)
EP (1) EP0374531B1 (es)
JP (1) JP2901674B2 (es)
KR (2) KR0138651B1 (es)
AT (1) ATE105177T1 (es)
AU (1) AU635912B2 (es)
CA (1) CA2006105C (es)
DE (1) DE68915132T2 (es)
DK (1) DK174915B1 (es)
ES (1) ES2051968T3 (es)
IE (1) IE63952B1 (es)
IL (1) IL92700A (es)
NO (1) NO178605C (es)
NZ (1) NZ231791A (es)
PT (1) PT92614B (es)
ZA (1) ZA899857B (es)

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FR2673843B1 (fr) * 1991-03-14 1995-01-13 Centre Nat Rech Scient Composition pharmaceutique implantable, bioresorbable a base de poly(acide lactique), destinee a mettre en óoeuvre une antibiotherapie interne locale.
ATE175132T1 (de) * 1992-10-26 1999-01-15 Sanol Arznei Schwarz Gmbh Verfahren zur herstellung von mikrokapseln
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US5962427A (en) 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
US6074840A (en) 1994-02-18 2000-06-13 The Regents Of The University Of Michigan Recombinant production of latent TGF-beta binding protein-3 (LTBP-3)
US5763416A (en) 1994-02-18 1998-06-09 The Regent Of The University Of Michigan Gene transfer into bone cells and tissues
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
WO1996002275A1 (fr) * 1994-07-20 1996-02-01 Toyama Chemical Co., Ltd. Onguent buccal a liberation prolongee
US5660817A (en) 1994-11-09 1997-08-26 Gillette Canada, Inc. Desensitizing teeth with degradable particles
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US6329139B1 (en) 1995-04-25 2001-12-11 Discovery Partners International Automated sorting system for matrices with memory
US5874214A (en) 1995-04-25 1999-02-23 Irori Remotely programmable matrices with memories
US6017496A (en) 1995-06-07 2000-01-25 Irori Matrices with memories and uses thereof
US6416714B1 (en) * 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
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WO1997017063A1 (en) 1995-11-09 1997-05-15 Microbiological Research Authority Microencapsulated dna for vaccination and gene therapy
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US7923250B2 (en) 1997-07-30 2011-04-12 Warsaw Orthopedic, Inc. Methods of expressing LIM mineralization protein in non-osseous cells
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US6153210A (en) * 1997-08-14 2000-11-28 Periodontix, Inc. Use of locally delivered metal ions for treatment of periodontal disease
GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
US6406719B1 (en) 1998-05-13 2002-06-18 Microbiological Research Authority Encapsulation of bioactive agents
AU2763099A (en) 1998-06-22 2000-01-10 Charles E. Worden Enriched platelet wound healant
US20050037086A1 (en) * 1999-11-19 2005-02-17 Zycos Inc., A Delaware Corporation Continuous-flow method for preparing microparticles
DE10018221A1 (de) * 2000-04-12 2001-11-22 Fitzner Lothar Verwendung von Wachstumshormonen zur therapeutischen Behandlung von Zähnen, Zahnfleisch oder Kieferknochen
JP2003535122A (ja) * 2000-06-02 2003-11-25 ザイコス インク． 生物活性物質のための送達システム
JP2002128697A (ja) * 2000-10-20 2002-05-09 Nonomura Tomosuke 口腔治療予防剤
US6726898B2 (en) 2000-11-17 2004-04-27 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6576226B1 (en) * 2000-11-17 2003-06-10 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6610274B1 (en) * 2000-12-22 2003-08-26 Wallace J. Gardner Anti-inflammatory composition comprising tetracycline
US20040029842A1 (en) * 2001-12-18 2004-02-12 Gardner Wallace J. Triglyceride lowering, common cold and pneumonia prevention composition comprising tetracycline, and methods of treating or preventing diseases using same
US6682348B2 (en) 2002-03-29 2004-01-27 Orapharma, Inc. Dispensing apparatus and cartridge
US6958161B2 (en) 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
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JP4489761B2 (ja) 2003-03-14 2010-06-23 ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク マイクロ流体無膜交換装置を有する血液ベースの治療のためのシステム及び方法
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US7309232B2 (en) * 2003-10-10 2007-12-18 Dentigenix Inc. Methods for treating dental conditions using tissue scaffolds
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AU2007253702A1 (en) 2006-05-22 2007-11-29 The Trustees Of Columbia University In The City Of New York Systems and methods of microfluidic membraneless exchange using filtration of extraction fluid outlet streams
US20090081135A1 (en) * 2007-09-24 2009-03-26 Glen Jeffrey D Iodine-based oral antibacterial treatment methodology
US7976490B2 (en) * 2007-12-04 2011-07-12 Orapharma, Inc. Medicinal implant cartridge
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US8496606B2 (en) 2008-02-04 2013-07-30 The Trustees Of Columbia University In The City Of New York Fluid separation devices, systems and methods
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Also Published As

Publication number Publication date
IE63952B1 (en) 1995-06-28
ZA899857B (en) 1990-10-31
KR900009061A (ko) 1990-07-02
IL92700A (en) 1994-05-30
EP0374531A2 (en) 1990-06-27
US5366733A (en) 1994-11-22
KR900009045A (ko) 1990-07-02
DK655889D0 (da) 1989-12-21
IE894145L (en) 1990-06-22
ATE105177T1 (de) 1994-05-15
NO895167D0 (no) 1989-12-21
AU4707789A (en) 1990-06-28
EP0374531A3 (en) 1991-07-31
JP2901674B2 (ja) 1999-06-07
NZ231791A (en) 1992-05-26
CA2006105C (en) 2000-03-14
AU635912B2 (en) 1993-04-08
CA2006105A1 (en) 1990-06-22
DE68915132T2 (de) 1994-12-08
PT92614A (pt) 1990-06-29
PT92614B (pt) 1995-09-12
NO178605C (no) 1996-05-02
NO178605B (no) 1996-01-22
DK174915B1 (da) 2004-02-23
IL92700A0 (en) 1990-09-17
DK655889A (da) 1990-06-23
KR0143912B1 (ko) 1998-07-15
JPH02184620A (ja) 1990-07-19
EP0374531B1 (en) 1994-05-04
DE68915132D1 (de) 1994-06-09
KR0138651B1 (ko) 1998-05-15
NO895167L (no) 1990-06-25

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