KR900009045A - 치아질환 치료용 조성물 및 그 조성물의 투여장치 - Google Patents

치아질환 치료용 조성물 및 그 조성물의 투여장치

Info

Publication number
KR900009045A
KR900009045A KR1019890019474A KR890019474A KR900009045A KR 900009045 A KR900009045 A KR 900009045A KR 1019890019474 A KR1019890019474 A KR 1019890019474A KR 890019474 A KR890019474 A KR 890019474A KR 900009045 A KR900009045 A KR 900009045A
Authority
KR
South Korea
Prior art keywords
composition
administering
treatment
dry
therapeutic agent
Prior art date
Application number
KR1019890019474A
Other languages
English (en)
Other versions
KR0143912B1 (ko
Inventor
수잔 브리졸라라 낸시
제럴드 란질로티 마이클
로널드 로터 제임스
Original Assignee
아메리칸 사이아나밋드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 아메리칸 사이아나밋드 캄파니 filed Critical 아메리칸 사이아나밋드 캄파니
Publication of KR900009045A publication Critical patent/KR900009045A/ko
Application granted granted Critical
Publication of KR0143912B1 publication Critical patent/KR0143912B1/ko

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00Dental auxiliary appliances
    • A61C19/06Implements for therapeutic treatment
    • A61C19/063Medicament applicators for teeth or gums, e.g. treatment with fluorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063Periodont
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dentistry (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019890019474A 1988-12-22 1989-12-21 치아질환 치료용 조성물 및 그 조성물의 투여장치 KR0143912B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28907688A 1988-12-22 1988-12-22
US7/289,076 1988-12-22

Publications (2)

Publication Number Publication Date
KR900009045A true KR900009045A (ko) 1990-07-02
KR0143912B1 KR0143912B1 (ko) 1998-07-15

Family

ID=23109956

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019890019157A KR0138651B1 (ko) 1988-12-22 1989-12-21 치아질환을 경감시키는데 유용한 개선된 상분리-미소봉입된 제약학적 조성물
KR1019890019474A KR0143912B1 (ko) 1988-12-22 1989-12-21 치아질환 치료용 조성물 및 그 조성물의 투여장치

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1019890019157A KR0138651B1 (ko) 1988-12-22 1989-12-21 치아질환을 경감시키는데 유용한 개선된 상분리-미소봉입된 제약학적 조성물

Country Status (16)

Country Link
US (1) US5366733A (ko)
EP (1) EP0374531B1 (ko)
JP (1) JP2901674B2 (ko)
KR (2) KR0138651B1 (ko)
AT (1) ATE105177T1 (ko)
AU (1) AU635912B2 (ko)
CA (1) CA2006105C (ko)
DE (1) DE68915132T2 (ko)
DK (1) DK174915B1 (ko)
ES (1) ES2051968T3 (ko)
IE (1) IE63952B1 (ko)
IL (1) IL92700A (ko)
NO (1) NO178605C (ko)
NZ (1) NZ231791A (ko)
PT (1) PT92614B (ko)
ZA (1) ZA899857B (ko)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68918419T2 (de) * 1988-12-22 1995-05-04 American Cyanamid Co Durch Phasentrennung microinkapsulierte Arzneimittelzusammensetzung zur Verminderung der Zahnkrankheit.
FR2673843B1 (fr) * 1991-03-14 1995-01-13 Centre Nat Rech Scient Composition pharmaceutique implantable, bioresorbable a base de poly(acide lactique), destinee a mettre en óoeuvre une antibiotherapie interne locale.
DE59309257D1 (de) * 1992-10-26 1999-02-11 Sanol Arznei Schwarz Gmbh Verfahren zur herstellung von mikrokapseln
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US5942496A (en) 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US5962427A (en) 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
US5763416A (en) 1994-02-18 1998-06-09 The Regent Of The University Of Michigan Gene transfer into bone cells and tissues
US6074840A (en) 1994-02-18 2000-06-13 The Regents Of The University Of Michigan Recombinant production of latent TGF-beta binding protein-3 (LTBP-3)
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
WO1996002275A1 (fr) * 1994-07-20 1996-02-01 Toyama Chemical Co., Ltd. Onguent buccal a liberation prolongee
US5660817A (en) 1994-11-09 1997-08-26 Gillette Canada, Inc. Desensitizing teeth with degradable particles
US5612052A (en) * 1995-04-13 1997-03-18 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
US6413539B1 (en) 1996-10-31 2002-07-02 Poly-Med, Inc. Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
US6551610B2 (en) 1995-04-13 2003-04-22 Poly-Med, Inc. Multifaceted compositions for post-surgical adhesion prevention
US6329139B1 (en) 1995-04-25 2001-12-11 Discovery Partners International Automated sorting system for matrices with memory
US5751629A (en) 1995-04-25 1998-05-12 Irori Remotely programmable matrices with memories
US6416714B1 (en) * 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
US6017496A (en) 1995-06-07 2000-01-25 Irori Matrices with memories and uses thereof
US6331273B1 (en) 1995-04-25 2001-12-18 Discovery Partners International Remotely programmable matrices with memories
US5874214A (en) 1995-04-25 1999-02-23 Irori Remotely programmable matrices with memories
US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
EP0862419B2 (en) 1995-11-09 2010-11-17 Microbiological Research Authority Microencapsulated dna for vaccination and gene therapy
SE513475C2 (sv) * 1996-11-22 2000-09-18 Peridoc Ab Hudsticktestkit
US20020182258A1 (en) * 1997-01-22 2002-12-05 Zycos Inc., A Delaware Corporation Microparticles for delivery of nucleic acid
US7923250B2 (en) 1997-07-30 2011-04-12 Warsaw Orthopedic, Inc. Methods of expressing LIM mineralization protein in non-osseous cells
JP4302877B2 (ja) 1997-07-30 2009-07-29 エモリー・ユニバーシテイ 新規な骨鉱化蛋白質、dna、ベクター及び発現系
US6153210A (en) * 1997-08-14 2000-11-28 Periodontix, Inc. Use of locally delivered metal ions for treatment of periodontal disease
GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
US6406719B1 (en) 1998-05-13 2002-06-18 Microbiological Research Authority Encapsulation of bioactive agents
MXPA00000009A (es) 1998-06-22 2005-09-08 Autologous Wound Therapy Inc Solicitud para patente de utilidad para curativo de heridas mejorado enriquecido con plaquetas.
US20050037086A1 (en) * 1999-11-19 2005-02-17 Zycos Inc., A Delaware Corporation Continuous-flow method for preparing microparticles
DE10018221A1 (de) * 2000-04-12 2001-11-22 Fitzner Lothar Verwendung von Wachstumshormonen zur therapeutischen Behandlung von Zähnen, Zahnfleisch oder Kieferknochen
AU6815901A (en) * 2000-06-02 2001-12-17 Zycos Inc Delivery systems for bioactive agents
JP2002128697A (ja) * 2000-10-20 2002-05-09 Nonomura Tomosuke 口腔治療予防剤
US6726898B2 (en) 2000-11-17 2004-04-27 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6576226B1 (en) * 2000-11-17 2003-06-10 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6610274B1 (en) * 2000-12-22 2003-08-26 Wallace J. Gardner Anti-inflammatory composition comprising tetracycline
US20040029842A1 (en) * 2001-12-18 2004-02-12 Gardner Wallace J. Triglyceride lowering, common cold and pneumonia prevention composition comprising tetracycline, and methods of treating or preventing diseases using same
US6682348B2 (en) 2002-03-29 2004-01-27 Orapharma, Inc. Dispensing apparatus and cartridge
US6958161B2 (en) 2002-04-12 2005-10-25 F H Faulding & Co Limited Modified release coated drug preparation
US20060076295A1 (en) 2004-03-15 2006-04-13 The Trustees Of Columbia University In The City Of New York Systems and methods of blood-based therapies having a microfluidic membraneless exchange device
ATE510605T1 (de) 2003-03-14 2011-06-15 Univ Columbia Systeme und verfahren für auf blut basierende therapien mit einer membranlosen mikrofluid- austauschvorrichtung
US20040185009A1 (en) * 2003-03-19 2004-09-23 Dexcel Pharma Technologies Ltd. Composition and device for treating periodontal diseases
US7309232B2 (en) * 2003-10-10 2007-12-18 Dentigenix Inc. Methods for treating dental conditions using tissue scaffolds
US20050079187A1 (en) * 2003-10-14 2005-04-14 Gardner Wallace J. Composition, kit and method for reducing plaque formation, tooth decay and incidence of caries
CA2652173A1 (en) 2006-05-22 2007-11-29 Edward F. Leonard Systems and methods of microfluidic membraneless exchange using filtration of extraction fluid outlet streams
US20090081135A1 (en) * 2007-09-24 2009-03-26 Glen Jeffrey D Iodine-based oral antibacterial treatment methodology
US7976491B2 (en) * 2007-12-04 2011-07-12 Orapharma, Inc. Actuators for device for delivering medicinal implants
US7976490B2 (en) * 2007-12-04 2011-07-12 Orapharma, Inc. Medicinal implant cartridge
US7976489B2 (en) 2007-12-04 2011-07-12 Orapharma, Inc. Device for delivering medicinal implants
CA2714594A1 (en) 2008-02-04 2009-08-13 Edward F. Leonard Fluid separation devices, systems and methods
CN102256609B (zh) 2008-07-30 2014-02-19 米辛瑟斯有限公司 衍生自前胃胞外基质的组织支架
US8048021B2 (en) * 2008-12-02 2011-11-01 Orapharma, Inc. Medicinal implant device and cartridge
US8333729B2 (en) * 2009-04-07 2012-12-18 Polybiotics Llc Multi-dose delivery system
US8865198B2 (en) 2010-10-25 2014-10-21 Dexcel Pharma Technologies Ltd. Method for treating a periodontal disease
US20130005593A1 (en) * 2011-03-09 2013-01-03 Teles Flavia R F RNA-Oligonucleotide Quantification Technique for the Enumeration of Uncultivated Bacterial Species
US9402701B2 (en) 2013-10-22 2016-08-02 Profounda, Inc Positionable delivery device and method
US11571367B2 (en) * 2018-04-05 2023-02-07 Terrell F. Pannkuk Composition and method for endodontic debridement
US11147747B2 (en) * 2018-04-05 2021-10-19 Terrell F. Pannkuk Composition and method for endodontic debridement

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887699A (en) * 1969-03-24 1975-06-03 Seymour Yolles Biodegradable polymeric article for dispensing drugs
US4107071A (en) * 1977-02-16 1978-08-15 Capsulated Systems, Inc. Method of producing microcapsules and resulting product
US4732763A (en) * 1978-10-17 1988-03-22 Stolle Research And Development Corporation Active/passive immunization of the internal female reproductive organs
US4622244A (en) * 1979-09-04 1986-11-11 The Washington University Process for preparation of microcapsules
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
US4515771A (en) * 1983-04-11 1985-05-07 Fine Daniel H Composition and method for the preventative treatment of dental disease and apparatus for dispensing said composition
US4685883A (en) * 1983-09-12 1987-08-11 Jernberg Gary R Local delivery of chemotherapeutic agents for the treatment of periodontal disease
US4764377A (en) * 1983-10-07 1988-08-16 The Forsyth Dental Infirmary For Children Intra-pocket drug delivery devices for treatment of periodontal diseases
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
US4701320A (en) * 1984-11-29 1987-10-20 Lederle (Japan), Ltd. Composition stably containing minocycline for treating periodontal diseases
JPS62223112A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
US4780320A (en) * 1986-04-29 1988-10-25 Pharmetrix Corp. Controlled release drug delivery system for the periodontal pocket
US4919939A (en) * 1986-04-29 1990-04-24 Pharmetrix Corporation Periodontal disease treatment system
US4954381A (en) * 1986-12-30 1990-09-04 The Research Foundation Of The State University Of New York Preparation of porous substrates having well defined morphology
US5000886A (en) * 1987-05-26 1991-03-19 American Cyanamid Company Silicone-hardened pharmaceutical microcapsules and process of making the same
DE68918419T2 (de) * 1988-12-22 1995-05-04 American Cyanamid Co Durch Phasentrennung microinkapsulierte Arzneimittelzusammensetzung zur Verminderung der Zahnkrankheit.
US4935171A (en) * 1989-01-27 1990-06-19 Vestar, Inc. Method for vesicle formation

Also Published As

Publication number Publication date
ZA899857B (en) 1990-10-31
IL92700A (en) 1994-05-30
PT92614A (pt) 1990-06-29
AU635912B2 (en) 1993-04-08
JP2901674B2 (ja) 1999-06-07
EP0374531A2 (en) 1990-06-27
NO178605B (no) 1996-01-22
KR0138651B1 (ko) 1998-05-15
KR900009061A (ko) 1990-07-02
NO895167D0 (no) 1989-12-21
JPH02184620A (ja) 1990-07-19
IL92700A0 (en) 1990-09-17
DK174915B1 (da) 2004-02-23
CA2006105C (en) 2000-03-14
IE63952B1 (en) 1995-06-28
AU4707789A (en) 1990-06-28
EP0374531A3 (en) 1991-07-31
DK655889D0 (da) 1989-12-21
EP0374531B1 (en) 1994-05-04
NO178605C (no) 1996-05-02
CA2006105A1 (en) 1990-06-22
DE68915132T2 (de) 1994-12-08
ES2051968T3 (es) 1994-07-01
NZ231791A (en) 1992-05-26
KR0143912B1 (ko) 1998-07-15
US5366733A (en) 1994-11-22
IE894145L (en) 1990-06-22
DK655889A (da) 1990-06-23
ATE105177T1 (de) 1994-05-15
PT92614B (pt) 1995-09-12
NO895167L (no) 1990-06-25
DE68915132D1 (de) 1994-06-09

Similar Documents

Publication Publication Date Title
KR900009045A (ko) 치아질환 치료용 조성물 및 그 조성물의 투여장치
ES8608848A1 (es) Un dispositivo de suministro y mantenimiento de agente terapeutico para suministrar un nivel farmacologicamente eficaz de agente terapeutico al sitio de una infeccion periodontal.
DE69016755D1 (de) Pharmazeutische Zubereitung mit verzögerter Freisetzung zur Behandlung periodontaler Erkrankungen.
EP1392364B1 (en) Liquid polymer composition for prevention and treatment of the oral cavity diseases
Barkin et al. Acute allergic reaction to eugenol
KR900700073A (ko) 결합 유도 조성물
Alleyn et al. The effect of chlorhexidine treatment of root surfaces on the attachment of human gingival fibroblasts in vitro
Milani et al. Effect of topical anesthesia with lidocaine-prilocaine (EMLA) cream and local pressure on pain during infiltration injection for maxillary canines: a randomized double-blind clinical trial
RU2624131C1 (ru) Способ лечения хронических апикальных периодонтитов
Kleier et al. Effects of formocresol on posttreatment pain of endodontic origin in vital molars
CA2006106A1 (en) Improved phase separation-microencapsulated pharmaceutical compositions useful for alleviating dental disease
Fuks et al. Glutaraldehyde as a pulp dressing after pulpotomy in primary teeth of baboon monkeys
Hirschfeld et al. New sustained release dosage form of chlorhexidine for dental use: use for plaque control in partial denture wearers
Kadam et al. Proximal Contact Areas: A Forsaken Facet of Restorative Dentistry
Polyzois Custom mouth protectors: an aid for autistic children.
Zukić et al. ROLE OF SERRAPEPTASE ON TRISMUS AFTER SURGICAL REMOVAL OF MANDIBULAR THIRD MOLAR.
RU2146900C1 (ru) Способ стимуляции задержавшихся в прорезывании постоянных зубов
Schindler et al. Apical closure in the presence of pulpal necrosis: report of two cases
Sykes An interim extraoral prosthesis used for the rehabilitation of a patient treated for osteoradionecrosis of the mandible: a clinical report
IONAŞ et al. SPLINTING-A NEW METHOD OF AESTHETIC PERIODONTAL IMMOBILIZATION.
Grzesiak-Janas et al. Influence of laser radiation on acceleration of postextraction wound healing
Coverly Osseous coagulum: a histologic study
JPH06287132A (ja) 咬合性外傷の治療剤
Limardi et al. Periodontal Healing with Citric ACID Root Conditioning
Murphy The biophysiological aspects of full maxillary immediate denture insertion: a critical review

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20120329

Year of fee payment: 15

EXPY Expiration of term