ES2013323A6 - Procedimiento de obtencion de nuevos compuestos intermedios de utilidad para la preparacion de sacaridos adecuados como medicamentos. - Google Patents

Procedimiento de obtencion de nuevos compuestos intermedios de utilidad para la preparacion de sacaridos adecuados como medicamentos.

Info

Publication number
ES2013323A6
ES2013323A6 ES8702969A ES8702969A ES2013323A6 ES 2013323 A6 ES2013323 A6 ES 2013323A6 ES 8702969 A ES8702969 A ES 8702969A ES 8702969 A ES8702969 A ES 8702969A ES 2013323 A6 ES2013323 A6 ES 2013323A6
Authority
ES
Spain
Prior art keywords
hydroxytetradecanoyl
hydrogen
group
represent
saccharides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8702969A
Other languages
English (en)
Inventor
Ingolf Macher
Frank Michael Unger
Christian R H Raetz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT193885A external-priority patent/ATA193885A/de
Priority claimed from AT193585A external-priority patent/ATA193585A/de
Priority claimed from AT193685A external-priority patent/ATA193685A/de
Priority claimed from AT193785A external-priority patent/ATA193785A/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES2013323A6 publication Critical patent/ES2013323A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04—Phosphates; Phosphites; Polyphosphates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE NUEVOS COMPUESTOS INTERMEDIOS DE UTILIDAD PARA LA PREPARACION DE SACARIDOS ADECUADOS COMO MEDICAMENTOS, DE FORMULA (III) EN DONDE LOS RADICALES TIENEN LOS SIGNIFICADOS INDICADOS EN LA DESCRIPCION. COMPRENDE CONVERTIR EL GRUPO HIDROXI SIN PROTEGER, QUE ESTA PRESENTE EN UN COMPUESTO DE FORMULA (IV), EN UN GRUPO ESTER FOSFATO PROTEGIDO; O BIEN ACILAR UN COMPUESTO DE FORMULA (IIIC).
ES8702969A 1985-06-28 1987-10-16 Procedimiento de obtencion de nuevos compuestos intermedios de utilidad para la preparacion de sacaridos adecuados como medicamentos. Expired - Lifetime ES2013323A6 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AT193885A ATA193885A (de) 1985-06-28 1985-06-28 Verfahren zur herstellung neuer 3-amino-3-desoxy- d-glucosederivate
AT193585A ATA193585A (de) 1985-06-28 1985-06-28 Verfahren zur herstellung neuer disaccharide
AT193685A ATA193685A (de) 1985-06-28 1985-06-28 Verfahren zur herstellung von glucosaminderivaten
AT193785A ATA193785A (de) 1985-06-28 1985-06-28 Verfahren zur herstellung neuer glucosederivate
AT122286 1986-05-07

Publications (1)

Publication Number Publication Date
ES2013323A6 true ES2013323A6 (es) 1990-05-01

Family

ID=27506246

Family Applications (2)

Application Number Title Priority Date Filing Date
ES868600029A Expired ES2000205A6 (es) 1985-06-28 1986-06-27 Procedimiento para la preparacion de sacaridos
ES8702969A Expired - Lifetime ES2013323A6 (es) 1985-06-28 1987-10-16 Procedimiento de obtencion de nuevos compuestos intermedios de utilidad para la preparacion de sacaridos adecuados como medicamentos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES868600029A Expired ES2000205A6 (es) 1985-06-28 1986-06-27 Procedimiento para la preparacion de sacaridos

Country Status (20)

Country Link
KR (1) KR870000351A (es)
AU (2) AU596800B2 (es)
BE (1) BE905010A (es)
CH (1) CH672789A5 (es)
DE (1) DE3621122A1 (es)
DK (1) DK304286A (es)
ES (2) ES2000205A6 (es)
FI (2) FI862723A (es)
FR (1) FR2584076A1 (es)
GB (1) GB2179945B (es)
HU (1) HU199494B (es)
IL (2) IL79247A0 (es)
IT (1) IT1203816B (es)
LU (1) LU86491A1 (es)
NL (1) NL8601551A (es)
PH (1) PH24438A (es)
PL (2) PL151036B1 (es)
PT (1) PT82855B (es)
SE (1) SE8602854L (es)
WO (1) WO1987000174A2 (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3731953A1 (de) 1987-09-23 1989-04-06 Sandoz Ag Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung
ATE139699T1 (de) * 1988-08-19 1996-07-15 Univ Australian Auf phosphozucker basierende antientzündliche und/oder immunitätsunterdrückende arzneimittel
AU627500B2 (en) * 1988-08-19 1992-08-27 Australian National University, The Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs
US5158939A (en) * 1989-07-21 1992-10-27 Wisconsin Alumni Research Foundation Method of stimulating the immune systems of animals and compositions useful therefor
DD295854A5 (de) * 1989-12-11 1991-11-14 ��@���������@�������k�� Lipid-a-austauschstoffe mit immunoaktivierender und antitumorwirkung
US5530113A (en) * 1991-10-11 1996-06-25 Eisai Co., Ltd. Anti-endotoxin compounds
AU660325B2 (en) * 1991-10-11 1995-06-22 Eisai Co. Ltd. Anti-endotoxin compounds and related molecules and methods
EP0668289A4 (en) * 1993-09-07 1998-10-21 Suntory Ltd NEW DISACCHARIDE DERIVATIVE.
US5681824A (en) * 1995-06-05 1997-10-28 Eisai Co., Ltd. Substituted liposaccharides useful in the treatment and prevention of endotoxemia
DE19740357A1 (de) * 1997-09-13 1999-03-18 Martin Wilhelm Phosphoryliertes Zuckermolekül
CN113214329A (zh) * 2020-01-21 2021-08-06 上海医药工业研究院 Lipid X及其中间体的制备方法、其中间体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL37955A0 (en) * 1970-11-13 1971-12-29 Ciba Geigy Ag O-esters of monosaccharides,their manufacture and pharmaceutical compositions containing them
JPS60501259A (ja) * 1983-05-06 1985-08-08 ウイスコンシン・アルムニ・リサ−チ・フアンデ−シヨン 免疫刺激活性をもつ単糖類化合物
HU197584B (en) * 1984-04-21 1989-04-28 Sandoz Ag Process for producing 2,3-diamino-2,3-dideoxy-hexose derivatives and pharmaceuticals comprising same as active ingredient
GR860379B (en) * 1985-02-22 1986-06-11 Akzo Nv Novel disaccharide and trisaccharide derivatives of the lipid a type

Also Published As

Publication number Publication date
FR2584076A1 (fr) 1987-01-02
HU199494B (en) 1990-02-28
BE905010A (fr) 1986-12-29
AU5931386A (en) 1987-01-08
PH24438A (en) 1990-06-25
PT82855A (en) 1986-07-01
ES2000205A6 (es) 1988-01-16
FI862723A0 (fi) 1986-06-26
SE8602854D0 (sv) 1986-06-26
WO1987000174A2 (fr) 1987-01-15
HUT42499A (en) 1987-07-28
IL91862A0 (en) 1990-06-10
DK304286A (da) 1986-12-29
FI862723A (fi) 1986-12-29
IT1203816B (it) 1989-02-23
DK304286D0 (da) 1986-06-26
AU4798990A (en) 1990-05-10
GB2179945B (en) 1989-11-15
IL79247A0 (en) 1986-09-30
FI900588A0 (fi) 1990-02-06
WO1987000174A3 (fr) 1987-10-22
IT8648204A0 (it) 1986-06-30
PL151036B1 (en) 1990-07-31
PL151094B1 (en) 1990-07-31
LU86491A1 (fr) 1987-01-13
DE3621122A1 (de) 1987-01-22
SE8602854L (sv) 1986-12-29
PT82855B (pt) 1988-12-15
PL271248A1 (en) 1989-01-23
KR870000351A (ko) 1987-02-18
NL8601551A (nl) 1987-01-16
GB8615617D0 (en) 1986-07-30
AU596800B2 (en) 1990-05-17
CH672789A5 (es) 1989-12-29
GB2179945A (en) 1987-03-18

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Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2007-10-16

FD1A Patent lapsed

Effective date: 20000301