ES2012510A6 - Procedimiento para la produccion de derivados de calcitonina - Google Patents

Procedimiento para la produccion de derivados de calcitonina

Info

Publication number
ES2012510A6
ES2012510A6 ES8603267A ES8603267A ES2012510A6 ES 2012510 A6 ES2012510 A6 ES 2012510A6 ES 8603267 A ES8603267 A ES 8603267A ES 8603267 A ES8603267 A ES 8603267A ES 2012510 A6 ES2012510 A6 ES 2012510A6
Authority
ES
Spain
Prior art keywords
radical
alpha
amino acid
aminoacyl
calcitonin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8603267A
Other languages
English (en)
Spanish (es)
Inventor
Francois Cardinaux
Janos Pless
Robert Helmut Buck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES2012510A6 publication Critical patent/ES2012510A6/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ES8603267A 1985-12-04 1986-12-03 Procedimiento para la produccion de derivados de calcitonina Expired - Lifetime ES2012510A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3542859 1985-12-04
DE3614784 1986-05-02

Publications (1)

Publication Number Publication Date
ES2012510A6 true ES2012510A6 (es) 1990-04-01

Family

ID=25838500

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8603267A Expired - Lifetime ES2012510A6 (es) 1985-12-04 1986-12-03 Procedimiento para la produccion de derivados de calcitonina

Country Status (20)

Country Link
US (1) US4758550A (enExample)
JP (1) JPH085916B2 (enExample)
KR (1) KR880006263A (enExample)
AU (1) AU600242B2 (enExample)
BE (1) BE905849A (enExample)
CH (1) CH671229A5 (enExample)
DK (1) DK580186A (enExample)
ES (1) ES2012510A6 (enExample)
FI (1) FI864939A7 (enExample)
FR (1) FR2590902B1 (enExample)
GB (1) GB2184729B (enExample)
GR (1) GR862836B (enExample)
HU (1) HUT44794A (enExample)
IL (1) IL80846A0 (enExample)
IT (1) IT1214754B (enExample)
LU (1) LU86697A1 (enExample)
NL (1) NL8602950A (enExample)
NZ (1) NZ218473A (enExample)
PT (1) PT83835B (enExample)
SE (1) SE8605189L (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2051647A1 (es) * 1992-12-10 1994-06-16 Lipotec Sa Procedimiento para la preparacion de calcitonina de salmon.

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2052642T3 (es) * 1987-07-08 1994-07-16 Mitsubishi Petrochemical Co Nuevo derivado de calcitonina y su sal.
AU609911B2 (en) * 1987-12-16 1991-05-09 Rorer International (Overseas) Inc. 8-glycine,16-x, des-19-leucine-calcitonin
GB2218102B (en) * 1988-04-08 1992-09-16 Sandoz Ltd Calcitonin peptide derivatives
AU629552B2 (en) * 1988-06-16 1992-10-08 Teijin Limited S-sulfonated calcitonin derivatives
US5026825A (en) * 1988-09-08 1991-06-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Intranasal calcitonin formulations
EP0370165B1 (en) * 1988-11-24 1994-01-05 Mitsubishi Petrochemical Co., Ltd. Novel calcitonin derivative and salt thereof
FI913899A0 (fi) * 1989-02-23 1991-08-19 Rorer Int Holdings Terapeutiska aerosolblandningar.
US5204326A (en) * 1989-03-16 1993-04-20 Otsuka Pharmaceutical Co., Ltd. Polypeptide derivatives and calcium metabolism improving agent
BR9006746A (pt) * 1989-04-21 1991-08-06 Tsumura & Co Peptideo fisiologicamente ativo e agente regulador do metabolismo de calcio
US5364840A (en) * 1989-12-05 1994-11-15 Vical, Inc. Synthetic calcitonin peptides
US5175146A (en) * 1989-12-05 1992-12-29 Vical, Inc. Synthetic calcitonin peptides
CS89491A3 (en) * 1990-04-09 1992-01-15 Chugai Pharmaceutical Co Ltd Hybrid calcitonin
KR100310280B1 (ko) * 1992-12-31 2002-02-28 엘. 데이예를 카렌. 유도체화된칼시토닌
US5710244A (en) * 1992-12-31 1998-01-20 Labroo; Virender M. Derivatized calcitonins
AU1919595A (en) * 1994-02-09 1995-08-29 Brigham And Women's Hospital Gel-forming polypeptide derivatives
DE726075T1 (de) * 1995-02-08 1996-12-12 Therapicon Srl Nicht-inorganische pharmazeutische salzige Lösungen zur endonasale Verabreichung
KR960031478A (ko) * 1995-02-14 1996-09-17 성재갑 유비퀴틴 융합 인간 칼시토닌의 정제방법
US6034064A (en) * 1995-04-07 2000-03-07 Hoechst Pharmaceuticals & Chemicals K.K. Peptides and therapeutic agent for autoimmune diseases containing the same
US5721207A (en) * 1995-04-18 1998-02-24 Innapharma, Inc. Method for treatment of pain
JP4372345B2 (ja) 1998-02-13 2009-11-25 アミリン・ファーマシューティカルズ，インコーポレイテッド 新規な混合アミリン活性化合物
US6936584B1 (en) 1998-02-13 2005-08-30 Amylin Pharmaceuticals, Inc. Mixed amylin activity compounds
US8653238B2 (en) * 2006-02-27 2014-02-18 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for transport of molecules with enhanced release properties across biological barriers
EP2788370B1 (en) * 2011-12-09 2020-02-05 The Regents of The University of California Modified mini-hepcidin peptides and methods of using thereof
WO2013162729A1 (en) 2012-04-24 2013-10-31 The Board Of Trustees Of The Leland Stanford Junior University Method for delivery of small molecules and proteins across the cell wall of algae using molecular transporters

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3926938A (en) * 1974-08-12 1975-12-16 Armour Pharma Synthesis of salmon calcitonin
JPS51128993A (en) * 1975-05-01 1976-11-10 Tanpakushitsu Kenkyu Shiyoureikai Process for preparing new polypeptides
GB1592969A (en) * 1976-09-13 1981-07-15 Armour Pharma Hentriacontapeptides and preparation thereof
JPS60500054A (ja) * 1983-02-15 1985-01-17 ア−マ−・フア−マシユ−テイカル・カンパニ− デス−アスパラギン−３−カルシトニン
US4663309A (en) * 1983-06-29 1987-05-05 University Patents, Inc. Novel peptide hormones with calcitonin-like activity
GB8327346D0 (en) * 1983-10-12 1983-11-16 Morris H R Peptide
US4497732A (en) * 1983-10-21 1985-02-05 Armour Pharmaceutical Company 1A-Endo-glycine-calcitonin
US4537716A (en) * 1983-12-05 1985-08-27 Armour Pharmaceutical Co. Des-serine2 or des-glycine2 -leucine22 calcitonin
US4622386A (en) * 1985-03-28 1986-11-11 Armour Pharmaceutical Company [1,7-di-alanine]calcitonin
US4658014A (en) * 1985-12-20 1987-04-14 Kempe Tomas G Synthetic peptides with calcitonin-like activity
AU7468687A (en) * 1987-06-23 1989-01-05 Armour Pharmaceutical Company (n-acyl, 1,7-di-alanine) calcitonin

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2051647A1 (es) * 1992-12-10 1994-06-16 Lipotec Sa Procedimiento para la preparacion de calcitonina de salmon.

Also Published As

Publication number Publication date
JPH085916B2 (ja) 1996-01-24
GB8628739D0 (en) 1987-01-07
KR880006263A (ko) 1988-07-22
DK580186D0 (da) 1986-12-02
DK580186A (da) 1987-06-05
CH671229A5 (enExample) 1989-08-15
GB2184729A (en) 1987-07-01
NZ218473A (en) 1990-03-27
JPS62132898A (ja) 1987-06-16
IT1214754B (it) 1990-01-18
GB2184729B (en) 1990-07-25
AU6606186A (en) 1987-06-11
LU86697A1 (fr) 1987-07-24
AU600242B2 (en) 1990-08-09
PT83835A (en) 1986-12-01
FI864939A7 (fi) 1987-06-05
SE8605189D0 (sv) 1986-12-03
US4758550A (en) 1988-07-19
IT8648701A0 (it) 1986-12-04
FI864939A0 (fi) 1986-12-03
FR2590902B1 (fr) 1994-12-23
GR862836B (en) 1987-04-02
BE905849A (fr) 1987-06-03
FR2590902A1 (fr) 1987-06-05
PT83835B (pt) 1989-06-30
SE8605189L (sv) 1987-06-05
IL80846A0 (en) 1987-03-31
NL8602950A (nl) 1987-07-01
HUT44794A (en) 1988-04-28

Similar Documents

Publication Publication Date Title
ES2012510A6 (es) Procedimiento para la produccion de derivados de calcitonina
ATE71947T1 (de) Tetrapyrrol-therapiemittel.
ATE121755T1 (de) Deletionsanaloga von magaininpeptiden.
ES8504678A1 (es) Procedimiento para la preparacion de un derivado de insulina
SE9301911D0 (sv) New peptide derivatives
ATE154641T1 (de) Neues physiologisch aktives schweinepeptid (cnp- 53)
UA35592C2 (uk) Похідні оцтової кислоти
DE3582575D1 (de) Basische zubereitungen von chinoloncarbonsaeuren.
ATE14439T1 (de) Veraenderte d-retro cyclische hexapeptide, analoge von somatostatin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
IE781227L (en) New peptide derivatives.
ATE214698T1 (de) Neue carbamazepin hapten analoge
ES2012720A6 (es) Procedimiento para la obtencion de sales de adicion de acido de taurina o glicina amidada.
KR910016767A (ko) 신규한 펩티드
DE69029377D1 (de) Substituierungsanaloge von magaininpeptiden
KR900009606A (ko) 불소-함유 2-니트로 이미다졸 유도체 및 그를 함유하는 방사선 증감제
DE69218222D1 (de) Neue ganglioside-derivaten
GB1516515A (en) Process for the preparation of insulin analogues and derivatives thereof
ES437586A1 (es) Procedimiento para la produccion de un peptido.
DK0517778T3 (da) Vasoaktive vasotocinderivater
YU48094B (sh) Derivati fenoksietilamina i postupak za njihovo dobijanje
KR890008151A (ko) 키놀린 카르복산의 유도체
SE8703855D0 (sv) Vasoaktiva peptider
ATE55988T1 (de) Dihydropyridinderivat, verfahren zu seiner herstellung und dieses enthaltende pharmazeutische zusammensetzung.
ATE147268T1 (de) Hypoglycemische peptide
ES2000879A6 (es) Un procedimiento para preparar una sal de acido inorganico de cloruro de n-(1(s)-etoxicarbonil-3-fenilpropil)-l-alanilo