ES2012720A6 - Procedimiento para la obtencion de sales de adicion de acido de taurina o glicina amidada. - Google Patents
Procedimiento para la obtencion de sales de adicion de acido de taurina o glicina amidada.Info
- Publication number
- ES2012720A6 ES2012720A6 ES8901497A ES8901497A ES2012720A6 ES 2012720 A6 ES2012720 A6 ES 2012720A6 ES 8901497 A ES8901497 A ES 8901497A ES 8901497 A ES8901497 A ES 8901497A ES 2012720 A6 ES2012720 A6 ES 2012720A6
- Authority
- ES
- Spain
- Prior art keywords
- alpha
- amidated
- taurine
- glycine
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
- C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Detergent Compositions (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE SALES DE ADICION DE ACIDO DE TAURINA O GLICINA AMIDADA. SE HACE REACCIONAR UN ANION (I) DE TAURINA O GLICINA, CUYO GRUPO AMINO ESTA SUSTITUIDO POR UN GRUPO ACILO DE UN ACIDO CARBOXILICO DE UN 3, 7, 12 TRIHIDROXI-ESTEROIIDE, CON UN CATION (II) DE (A) UNA AMINA ALIFATICA, DEBIENDO TENER CUALESQUIERA SUSTITUYENTES DE LA MISMA UN SIGNIFICADO DIFERENTE DE GRUPOS CARBOXI, O DE (B) UN AMINOACIDO BASICO QUE TIENE UN GRUPO ALQUILENO DIVALENTE ENTRE EL GRUPO AMINOACIDO Y OTRO GRUPO AMINO, EN UN DISOLVENTE, PARTICULARMENTE EN MEDIO ACUOSO; SE SEPARA EL DISOLVENTE, EN PARTICULAR POR EVAPORIZACION; Y SE AISLA LA SAL DE ADICION DE ACIDO POR LIOFILIZACION. SE PUEDE UTILIZAR DICHA SAL DE ADICION DE ACIDO, POR EJEMPLO, COMO AGENTE FOMENTADOR DE LA RESORCION TRANSMUCOSA DE SUSTANCIAS ACTIVAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3814694 | 1988-04-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2012720A6 true ES2012720A6 (es) | 1990-04-01 |
Family
ID=6353289
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8901497A Expired - Lifetime ES2012720A6 (es) | 1988-04-30 | 1989-04-28 | Procedimiento para la obtencion de sales de adicion de acido de taurina o glicina amidada. |
Country Status (25)
Country | Link |
---|---|
US (1) | US5122520A (es) |
JP (1) | JPH0211598A (es) |
KR (1) | KR900016253A (es) |
AT (1) | AT396475B (es) |
AU (1) | AU624610B2 (es) |
BE (1) | BE1003817A3 (es) |
CH (1) | CH679309A5 (es) |
DE (1) | DE3913350A1 (es) |
DK (1) | DK210689A (es) |
ES (1) | ES2012720A6 (es) |
FI (1) | FI892052A (es) |
FR (1) | FR2630649B1 (es) |
GB (1) | GB2218098B (es) |
GR (1) | GR890100285A (es) |
HU (1) | HU206367B (es) |
IL (1) | IL90115A0 (es) |
IT (1) | IT1232828B (es) |
LU (1) | LU87509A1 (es) |
MY (1) | MY106287A (es) |
NL (1) | NL8901059A (es) |
NO (1) | NO173447C (es) |
NZ (1) | NZ228928A (es) |
PT (1) | PT90415B (es) |
SE (1) | SE8901552L (es) |
ZA (1) | ZA893201B (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2151838A1 (es) * | 1997-09-05 | 2001-01-01 | Alfa Wassermann Spa | Composiciones farmaceuticas que contienen calcitonina en un dosificador de pulverizado para administracion intranasal. |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1247489B (it) * | 1991-04-17 | 1994-12-17 | Prodotti Chimici Alimentari | Acido metiltauroursodesossicolico e suoi derivati terapeuticamente attivi procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono |
DE4222647A1 (de) * | 1991-07-15 | 1993-01-21 | Sandoz Ag | Peptid-zubereitungen |
US5795870A (en) * | 1991-12-13 | 1998-08-18 | Trustees Of Princeton University | Compositions and methods for cell transformation |
US5693769A (en) * | 1991-12-13 | 1997-12-02 | Transcell Technologies, Inc. | Glycosylated steroid derivatives for transport across biological membranes and process for making and using same |
US5780444A (en) * | 1991-12-13 | 1998-07-14 | Trustees Of Princeton University | Compositions and methods for cell transformation |
US5338837A (en) * | 1991-12-13 | 1994-08-16 | The Trustees Of Princeton University | Glycosylated steroid derivatives for transport across biological membranes and process for making same |
IT1258788B (it) * | 1992-01-17 | 1996-02-29 | Giuliani Spa | Derivati solforati di acidi biliari |
GB9212511D0 (en) * | 1992-06-12 | 1992-07-22 | Cortecs Ltd | Pharmaceutical compositions |
IT1270853B (it) * | 1993-05-20 | 1997-05-13 | Sanofi Elf | Procedimento per la preparazione di derivati taurocolanici |
US5583239A (en) * | 1995-05-30 | 1996-12-10 | Lehigh University | Antimicrobial sterol conjugates |
US5834453A (en) * | 1995-05-30 | 1998-11-10 | Lehigh University | Methods for the manufacture and use of antimicrobial sterol conjugates |
KR100611559B1 (ko) * | 1998-05-08 | 2007-04-25 | 동아제약주식회사 | 칼시토닌을 함유한 비강투여용 약제학적 조성물 |
JP4790123B2 (ja) * | 1998-07-24 | 2011-10-12 | ヨー、セオ、ホン | 胆汁酸を有する透明水溶液型製剤の調剤 |
US20070243043A1 (en) * | 2006-04-17 | 2007-10-18 | Acument Intellectual Properties, Llc | High performance thread forming screw |
US11554126B2 (en) * | 2017-12-15 | 2023-01-17 | Georgetown University | Methods of treating residual lesions of vascular anomalies |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1034358A (en) * | 1963-05-01 | 1966-06-29 | Chugai Pharmaceutical Co Ltd | Body-protein-biosynthesis promoting composition |
US3622669A (en) * | 1967-10-23 | 1971-11-23 | Merck & Co Inc | 5{62 -taurocholenic acids and 5{62 -taurocholadienic acids in compositions for reducing the concentration of cholesterol and liads in blood serum |
US3839565A (en) * | 1972-10-31 | 1974-10-01 | Intellectual Property Dev Corp | Chemical process |
DE2349186C2 (de) * | 1972-11-16 | 1982-11-11 | Solco Basel AG, Birsfelden | Arzneimittel zur Verbesserung der Zellatmung, der Herzmuskelleistung und der Hirnfunktion |
US3856953A (en) * | 1973-05-15 | 1974-12-24 | Intellectual Property Dev Corp | Method of treating fatty liver |
US4104285A (en) * | 1977-04-22 | 1978-08-01 | Hoffmann-La Roche Inc. | Taurine and glycine derivatives |
EP0111841B1 (en) * | 1982-12-10 | 1987-05-06 | Syntex (U.S.A.) Inc. | Lhrh preparations for intranasal administration |
IL70489A0 (en) * | 1982-12-29 | 1984-03-30 | Armour Pharma | Pharmaceutical compositions containing calcitonin |
JPS59141510A (ja) * | 1983-01-31 | 1984-08-14 | Shiseido Co Ltd | 乳化組成物 |
US4746508A (en) * | 1983-06-06 | 1988-05-24 | Beth Israel Hospital Assn. | Drug administration |
IT1212835B (it) * | 1983-08-18 | 1989-11-30 | Lehner Ag | Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche. |
BE902888A (fr) * | 1985-07-12 | 1985-11-04 | Ripari Gero Ist Farm Biolog | Composes regulateurs de la fonction biliaire |
US4777043A (en) * | 1985-12-17 | 1988-10-11 | Genentech, Inc. | Stabilized human tissue plasminogen activator compositions |
DE3623747A1 (de) * | 1986-07-14 | 1988-01-21 | Remedia Pharmazeutische Praepa | Stoffe zur experimentellen untersuchung von membranproteinen und verfahren zu deren herstellung |
GB2193891B (en) * | 1986-08-18 | 1990-07-25 | Sandoz Ltd | Nasal pharmaceutical composition containing a somatostatin anologue. |
JP2505430B2 (ja) * | 1986-11-04 | 1996-06-12 | 帝人株式会社 | 塩基性アミノ酸を含有する経鼻投与用粉末状組成物 |
JPS63115822A (ja) * | 1986-11-04 | 1988-05-20 | Teijin Ltd | 生理活性ポリペプチド類の経鼻投与用粉末状組成物 |
CH674369A5 (es) * | 1986-11-26 | 1990-05-31 | Jago Res Ag |
-
1989
- 1989-04-20 HU HU891922A patent/HU206367B/hu not_active IP Right Cessation
- 1989-04-22 DE DE3913350A patent/DE3913350A1/de not_active Withdrawn
- 1989-04-26 GR GR890100285A patent/GR890100285A/el unknown
- 1989-04-27 FR FR898905784A patent/FR2630649B1/fr not_active Expired - Lifetime
- 1989-04-27 GB GB8909679A patent/GB2218098B/en not_active Expired - Lifetime
- 1989-04-27 CH CH1604/89A patent/CH679309A5/de not_active IP Right Cessation
- 1989-04-27 NL NL8901059A patent/NL8901059A/nl not_active Application Discontinuation
- 1989-04-27 BE BE8900466A patent/BE1003817A3/fr not_active IP Right Cessation
- 1989-04-27 LU LU87509A patent/LU87509A1/fr unknown
- 1989-04-27 NO NO891749A patent/NO173447C/no unknown
- 1989-04-28 ES ES8901497A patent/ES2012720A6/es not_active Expired - Lifetime
- 1989-04-28 NZ NZ228928A patent/NZ228928A/en unknown
- 1989-04-28 PT PT90415A patent/PT90415B/pt not_active IP Right Cessation
- 1989-04-28 AT AT0102389A patent/AT396475B/de not_active IP Right Cessation
- 1989-04-28 SE SE8901552A patent/SE8901552L/ not_active Application Discontinuation
- 1989-04-28 JP JP1111917A patent/JPH0211598A/ja active Pending
- 1989-04-28 MY MYPI89000576A patent/MY106287A/en unknown
- 1989-04-28 AU AU33865/89A patent/AU624610B2/en not_active Ceased
- 1989-04-28 IL IL90115A patent/IL90115A0/xx unknown
- 1989-04-28 ZA ZA893201A patent/ZA893201B/xx unknown
- 1989-04-28 DK DK210689A patent/DK210689A/da not_active Application Discontinuation
- 1989-04-28 FI FI892052A patent/FI892052A/fi not_active Application Discontinuation
- 1989-04-29 KR KR1019890005863A patent/KR900016253A/ko not_active Application Discontinuation
- 1989-05-02 IT IT8947901A patent/IT1232828B/it active
-
1991
- 1991-02-22 US US07/659,788 patent/US5122520A/en not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2151838A1 (es) * | 1997-09-05 | 2001-01-01 | Alfa Wassermann Spa | Composiciones farmaceuticas que contienen calcitonina en un dosificador de pulverizado para administracion intranasal. |
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20000201 |