DE69218222D1 - Neue ganglioside-derivaten - Google Patents

Neue ganglioside-derivaten

Info

Publication number
DE69218222D1
DE69218222D1 DE69218222T DE69218222T DE69218222D1 DE 69218222 D1 DE69218222 D1 DE 69218222D1 DE 69218222 T DE69218222 T DE 69218222T DE 69218222 T DE69218222 T DE 69218222T DE 69218222 D1 DE69218222 D1 DE 69218222D1
Authority
DE
Germany
Prior art keywords
ganglioside
lyso
gangliosides
acyl
semisynthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69218222T
Other languages
English (en)
Other versions
DE69218222T2 (de
Inventor
Aurelio Romeo
Gino Toffano
Alberta Leon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia SpA
Original Assignee
Fidia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia SpA filed Critical Fidia SpA
Publication of DE69218222D1 publication Critical patent/DE69218222D1/de
Application granted granted Critical
Publication of DE69218222T2 publication Critical patent/DE69218222T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69218222T 1991-08-01 1992-08-01 Neue ganglioside-derivaten Expired - Fee Related DE69218222T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITPD910139A IT1253832B (it) 1991-08-01 1991-08-01 Derivati di gangliosidi
PCT/EP1992/001776 WO1993003049A1 (en) 1991-08-01 1992-08-01 New ganglioside derivatives

Publications (2)

Publication Number Publication Date
DE69218222D1 true DE69218222D1 (de) 1997-04-17
DE69218222T2 DE69218222T2 (de) 1997-10-09

Family

ID=11389659

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69218222T Expired - Fee Related DE69218222T2 (de) 1991-08-01 1992-08-01 Neue ganglioside-derivaten

Country Status (10)

Country Link
US (1) US5350841A (de)
EP (1) EP0599908B1 (de)
JP (1) JPH06509350A (de)
AT (1) ATE150028T1 (de)
AU (1) AU2426592A (de)
DE (1) DE69218222T2 (de)
ES (1) ES2100360T3 (de)
IT (1) IT1253832B (de)
PT (1) PT100756B (de)
WO (1) WO1993003049A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407072B1 (en) * 1988-12-02 2002-06-18 Fidia S.P.A. Lysoganglioside derivatives
IT1232175B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Analoghi semisintetici di gangliosidi
IT1254280B (it) * 1992-03-13 1995-09-14 Fidia Spa Composizioni farmaceutiche comprendenti monosialoganglioside gm1 o un suo derivato atte al trattamento della malattia di parkinson
IT1267955B1 (it) * 1993-03-04 1997-02-18 Fidia S P A In Amministrazione Derivati solfatati dei lisogangliosidi
US5849717A (en) * 1993-03-04 1998-12-15 Fidia S.P.A. O-sulfated gangliosides and lyso-ganglioside derivatives
US5795869A (en) * 1993-03-04 1998-08-18 Fidia S.P.A. Sulfated lyso-ganglioside derivatives
IT1267956B1 (it) * 1993-03-04 1997-02-18 Fidia S P A In Amministrazione Derivati o-solfatati di gangliosidi e lisogangliosidi
US5789561A (en) * 1995-12-18 1998-08-04 Daikin Industries Ltd. Fluorine-substituted ganglioside GM3 derivative and intermediates therefor
EP1435972B1 (de) 2001-08-29 2016-03-09 Seneb Biosciences Inc. Neue synthetische gangliosid-derivate und zusammensetzungen davon
AU2004220087A1 (en) 2003-03-06 2004-09-23 Seneb Biosciences, Inc. Methods and compositions for the enzymatic synthesis of gangliosides
EP2410846B1 (de) * 2009-03-25 2016-09-07 Seneb Biosciences, Inc. Glycolipide zur behandlung von erkrankungen
WO2023102665A1 (en) * 2021-12-09 2023-06-15 The Governors Of The University Of Alberta Cellular and tissue clearance of misfolded proteins and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
IT1235161B (it) * 1988-12-02 1992-06-22 Fidia Farmaceutici Derivati di lisogangliosidi
IT1232175B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Analoghi semisintetici di gangliosidi
IT1232176B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Derivati di-lisogangliosidi
IT1238346B (it) * 1989-11-14 1993-07-13 Gangliosidi modificati e loro derivati funzionali.

Also Published As

Publication number Publication date
IT1253832B (it) 1995-08-29
PT100756B (pt) 1999-10-29
US5350841A (en) 1994-09-27
EP0599908B1 (de) 1997-03-12
AU2426592A (en) 1993-03-02
ATE150028T1 (de) 1997-03-15
WO1993003049A1 (en) 1993-02-18
ITPD910139A1 (it) 1993-02-01
ITPD910139A0 (it) 1991-08-01
JPH06509350A (ja) 1994-10-20
EP0599908A1 (de) 1994-06-08
DE69218222T2 (de) 1997-10-09
ES2100360T3 (es) 1997-06-16
PT100756A (pt) 1993-09-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee