ES2100360T3 - Nuevos derivados de gangliosidos. - Google Patents

Nuevos derivados de gangliosidos.

Info

Publication number
ES2100360T3
ES2100360T3 ES92917164T ES92917164T ES2100360T3 ES 2100360 T3 ES2100360 T3 ES 2100360T3 ES 92917164 T ES92917164 T ES 92917164T ES 92917164 T ES92917164 T ES 92917164T ES 2100360 T3 ES2100360 T3 ES 2100360T3
Authority
ES
Spain
Prior art keywords
acid
semi
derivatives
ganglioside
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92917164T
Other languages
English (en)
Inventor
Aurelio Romeo
Gino Toffano
Alberta Leon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fidia SpA
Original Assignee
Fidia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia SpA filed Critical Fidia SpA
Application granted granted Critical
Publication of ES2100360T3 publication Critical patent/ES2100360T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PREPARAN NUEVOS DERIVADOS DE GANGLIOSIDO QUE COMPRENDEN UNA BASE NATURAL O GANGLIOSIDO SEMISINTETICO, EN LOS CUALES EL GRUPO CARBOXILO DE LA PARTE SIALICA DEL GANGLIOSIDO NATURAL O SEMISINTETICO ES CONVERTIDO EN UNA CARBOXILOAMIDA CON UN ACIDO AMINO ALIFATICO CON UNA FUNCION ACIDO SULFURICA O CARBOXILICA, Y SALES DE ELLOS. LOS COMPONENTES GANGLIOSIDO SEMISINTETICOS SE PUEDEN ELEGIR DEL GRUPO COMPUESTO POR N GANGLIOSIDOS, N''ACILO ILO UNA MITAD DE UN ACIDO ALIFATICO OPCIONALMENTE SUSTITUIDO. LOS DERIVADOS GANGLIOSIDOS SE PUEDEN USAR EN PREPARACIONES FARMACEUTICAS PARA SER USADAS EN PATOLOGIAS DEL SISTEMA NERVIOSO.
ES92917164T 1991-08-01 1992-08-01 Nuevos derivados de gangliosidos. Expired - Lifetime ES2100360T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITPD910139A IT1253832B (it) 1991-08-01 1991-08-01 Derivati di gangliosidi

Publications (1)

Publication Number Publication Date
ES2100360T3 true ES2100360T3 (es) 1997-06-16

Family

ID=11389659

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92917164T Expired - Lifetime ES2100360T3 (es) 1991-08-01 1992-08-01 Nuevos derivados de gangliosidos.

Country Status (10)

Country Link
US (1) US5350841A (es)
EP (1) EP0599908B1 (es)
JP (1) JPH06509350A (es)
AT (1) ATE150028T1 (es)
AU (1) AU2426592A (es)
DE (1) DE69218222T2 (es)
ES (1) ES2100360T3 (es)
IT (1) IT1253832B (es)
PT (1) PT100756B (es)
WO (1) WO1993003049A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407072B1 (en) * 1988-12-02 2002-06-18 Fidia S.P.A. Lysoganglioside derivatives
IT1232175B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Analoghi semisintetici di gangliosidi
IT1254280B (it) * 1992-03-13 1995-09-14 Fidia Spa Composizioni farmaceutiche comprendenti monosialoganglioside gm1 o un suo derivato atte al trattamento della malattia di parkinson
IT1267955B1 (it) * 1993-03-04 1997-02-18 Fidia S P A In Amministrazione Derivati solfatati dei lisogangliosidi
US5849717A (en) * 1993-03-04 1998-12-15 Fidia S.P.A. O-sulfated gangliosides and lyso-ganglioside derivatives
US5795869A (en) * 1993-03-04 1998-08-18 Fidia S.P.A. Sulfated lyso-ganglioside derivatives
IT1267956B1 (it) * 1993-03-04 1997-02-18 Fidia S P A In Amministrazione Derivati o-solfatati di gangliosidi e lisogangliosidi
US5789561A (en) * 1995-12-18 1998-08-04 Daikin Industries Ltd. Fluorine-substituted ganglioside GM3 derivative and intermediates therefor
EP1435972B1 (en) 2001-08-29 2016-03-09 Seneb Biosciences Inc. Novel synthetic ganglioside derivatives and compositions thereof
AU2004220087A1 (en) 2003-03-06 2004-09-23 Seneb Biosciences, Inc. Methods and compositions for the enzymatic synthesis of gangliosides
EP2410846B1 (en) * 2009-03-25 2016-09-07 Seneb Biosciences, Inc. Glycolipids as treatment for disease
WO2023102665A1 (en) * 2021-12-09 2023-06-15 The Governors Of The University Of Alberta Cellular and tissue clearance of misfolded proteins and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
IT1235161B (it) * 1988-12-02 1992-06-22 Fidia Farmaceutici Derivati di lisogangliosidi
IT1232175B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Analoghi semisintetici di gangliosidi
IT1232176B (it) * 1989-07-27 1992-01-25 Fidia Farmaceutici Derivati di-lisogangliosidi
IT1238346B (it) * 1989-11-14 1993-07-13 Gangliosidi modificati e loro derivati funzionali.

Also Published As

Publication number Publication date
DE69218222D1 (de) 1997-04-17
IT1253832B (it) 1995-08-29
PT100756B (pt) 1999-10-29
US5350841A (en) 1994-09-27
EP0599908B1 (en) 1997-03-12
AU2426592A (en) 1993-03-02
ATE150028T1 (de) 1997-03-15
WO1993003049A1 (en) 1993-02-18
ITPD910139A1 (it) 1993-02-01
ITPD910139A0 (it) 1991-08-01
JPH06509350A (ja) 1994-10-20
EP0599908A1 (en) 1994-06-08
DE69218222T2 (de) 1997-10-09
PT100756A (pt) 1993-09-30

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