ES2100360T3 - Nuevos derivados de gangliosidos. - Google Patents
Nuevos derivados de gangliosidos.Info
- Publication number
- ES2100360T3 ES2100360T3 ES92917164T ES92917164T ES2100360T3 ES 2100360 T3 ES2100360 T3 ES 2100360T3 ES 92917164 T ES92917164 T ES 92917164T ES 92917164 T ES92917164 T ES 92917164T ES 2100360 T3 ES2100360 T3 ES 2100360T3
- Authority
- ES
- Spain
- Prior art keywords
- acid
- semi
- derivatives
- ganglioside
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000002270 gangliosides Chemical class 0.000 title abstract 6
- 239000002253 acid Substances 0.000 abstract 21
- -1 CARBOXYL GROUP Chemical group 0.000 abstract 1
- 210000000653 nervous system Anatomy 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE PREPARAN NUEVOS DERIVADOS DE GANGLIOSIDO QUE COMPRENDEN UNA BASE NATURAL O GANGLIOSIDO SEMISINTETICO, EN LOS CUALES EL GRUPO CARBOXILO DE LA PARTE SIALICA DEL GANGLIOSIDO NATURAL O SEMISINTETICO ES CONVERTIDO EN UNA CARBOXILOAMIDA CON UN ACIDO AMINO ALIFATICO CON UNA FUNCION ACIDO SULFURICA O CARBOXILICA, Y SALES DE ELLOS. LOS COMPONENTES GANGLIOSIDO SEMISINTETICOS SE PUEDEN ELEGIR DEL GRUPO COMPUESTO POR N GANGLIOSIDOS, N''ACILO ILO UNA MITAD DE UN ACIDO ALIFATICO OPCIONALMENTE SUSTITUIDO. LOS DERIVADOS GANGLIOSIDOS SE PUEDEN USAR EN PREPARACIONES FARMACEUTICAS PARA SER USADAS EN PATOLOGIAS DEL SISTEMA NERVIOSO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITPD910139A IT1253832B (it) | 1991-08-01 | 1991-08-01 | Derivati di gangliosidi |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2100360T3 true ES2100360T3 (es) | 1997-06-16 |
Family
ID=11389659
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92917164T Expired - Lifetime ES2100360T3 (es) | 1991-08-01 | 1992-08-01 | Nuevos derivados de gangliosidos. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5350841A (es) |
EP (1) | EP0599908B1 (es) |
JP (1) | JPH06509350A (es) |
AT (1) | ATE150028T1 (es) |
AU (1) | AU2426592A (es) |
DE (1) | DE69218222T2 (es) |
ES (1) | ES2100360T3 (es) |
IT (1) | IT1253832B (es) |
PT (1) | PT100756B (es) |
WO (1) | WO1993003049A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6407072B1 (en) * | 1988-12-02 | 2002-06-18 | Fidia S.P.A. | Lysoganglioside derivatives |
IT1232175B (it) * | 1989-07-27 | 1992-01-25 | Fidia Farmaceutici | Analoghi semisintetici di gangliosidi |
IT1254280B (it) * | 1992-03-13 | 1995-09-14 | Fidia Spa | Composizioni farmaceutiche comprendenti monosialoganglioside gm1 o un suo derivato atte al trattamento della malattia di parkinson |
IT1267955B1 (it) * | 1993-03-04 | 1997-02-18 | Fidia S P A In Amministrazione | Derivati solfatati dei lisogangliosidi |
US5849717A (en) * | 1993-03-04 | 1998-12-15 | Fidia S.P.A. | O-sulfated gangliosides and lyso-ganglioside derivatives |
IT1267956B1 (it) * | 1993-03-04 | 1997-02-18 | Fidia S P A In Amministrazione | Derivati o-solfatati di gangliosidi e lisogangliosidi |
US5795869A (en) * | 1993-03-04 | 1998-08-18 | Fidia S.P.A. | Sulfated lyso-ganglioside derivatives |
CA2213256C (en) * | 1995-12-18 | 2005-04-05 | Daikin Industries, Ltd. | Fluorine-substituted ganglioside gm3 derivative and intermediates therefor |
JP2005527467A (ja) | 2001-08-29 | 2005-09-15 | ネオーズ テクノロジーズ, インコーポレイテッド | 新規な合成ガングリオシド誘導体およびその組成物 |
EP1603932B1 (en) | 2003-03-06 | 2012-10-03 | Seneb Biosciences Inc. | Methods and compositions for the enzymatic synthesis of gangliosides |
WO2010111530A1 (en) | 2009-03-25 | 2010-09-30 | Seneb Biosciences, Inc. | Glycolipids as treatment for disease |
WO2023102665A1 (en) * | 2021-12-09 | 2023-06-15 | The Governors Of The University Of Alberta | Cellular and tissue clearance of misfolded proteins and uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1199116B (it) * | 1984-07-03 | 1988-12-30 | Fidia Farmaceutici | Derivati di gangliosidi |
IT1235161B (it) * | 1988-12-02 | 1992-06-22 | Fidia Farmaceutici | Derivati di lisogangliosidi |
IT1232175B (it) * | 1989-07-27 | 1992-01-25 | Fidia Farmaceutici | Analoghi semisintetici di gangliosidi |
IT1232176B (it) * | 1989-07-27 | 1992-01-25 | Fidia Farmaceutici | Derivati di-lisogangliosidi |
IT1238346B (it) * | 1989-11-14 | 1993-07-13 | Gangliosidi modificati e loro derivati funzionali. |
-
1991
- 1991-08-01 IT ITPD910139A patent/IT1253832B/it active IP Right Grant
-
1992
- 1992-07-31 PT PT100756A patent/PT100756B/pt not_active IP Right Cessation
- 1992-07-31 US US07/922,383 patent/US5350841A/en not_active Expired - Lifetime
- 1992-08-01 WO PCT/EP1992/001776 patent/WO1993003049A1/en active IP Right Grant
- 1992-08-01 ES ES92917164T patent/ES2100360T3/es not_active Expired - Lifetime
- 1992-08-01 JP JP5503281A patent/JPH06509350A/ja active Pending
- 1992-08-01 AU AU24265/92A patent/AU2426592A/en not_active Abandoned
- 1992-08-01 DE DE69218222T patent/DE69218222T2/de not_active Expired - Fee Related
- 1992-08-01 AT AT92917164T patent/ATE150028T1/de not_active IP Right Cessation
- 1992-08-01 EP EP92917164A patent/EP0599908B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69218222D1 (de) | 1997-04-17 |
AU2426592A (en) | 1993-03-02 |
PT100756A (pt) | 1993-09-30 |
EP0599908B1 (en) | 1997-03-12 |
WO1993003049A1 (en) | 1993-02-18 |
US5350841A (en) | 1994-09-27 |
ATE150028T1 (de) | 1997-03-15 |
ITPD910139A1 (it) | 1993-02-01 |
JPH06509350A (ja) | 1994-10-20 |
IT1253832B (it) | 1995-08-29 |
EP0599908A1 (en) | 1994-06-08 |
PT100756B (pt) | 1999-10-29 |
DE69218222T2 (de) | 1997-10-09 |
ITPD910139A0 (it) | 1991-08-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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