ES2009236A6 - Procedimiento para la preparacion de derivados de piperazina. - Google Patents
Procedimiento para la preparacion de derivados de piperazina.Info
- Publication number
- ES2009236A6 ES2009236A6 ES8800543A ES8800543A ES2009236A6 ES 2009236 A6 ES2009236 A6 ES 2009236A6 ES 8800543 A ES8800543 A ES 8800543A ES 8800543 A ES8800543 A ES 8800543A ES 2009236 A6 ES2009236 A6 ES 2009236A6
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- pyrimidinyl
- anxioselective
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- MRBFGEHILMYPTF-UHFFFAOYSA-N 1-(2-Pyrimidyl)piperazine Chemical class C1CNCCN1C1=NC=CC=N1 MRBFGEHILMYPTF-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- QWCRAEMEVRGPNT-UHFFFAOYSA-N buspirone Chemical compound C1C(=O)N(CCCCN2CCN(CC2)C=2N=CC=CN=2)C(=O)CC21CCCC2 QWCRAEMEVRGPNT-UHFFFAOYSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU71687A HU197313B (en) | 1987-02-25 | 1987-02-25 | Process for producing 8-azaspiro <4.5> decane-7,9-dione-8-propine-/2/ |
| HU71887A HU198477B (en) | 1987-02-25 | 1987-02-25 | Process for producing pyrimidinyl piperazine derivatives |
| HU71787A HU198204B (en) | 1987-02-25 | 1987-02-25 | Process for production of derivatives of piperasine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2009236A6 true ES2009236A6 (es) | 1989-09-16 |
Family
ID=27269942
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8800543A Expired ES2009236A6 (es) | 1987-02-25 | 1988-02-25 | Procedimiento para la preparacion de derivados de piperazina. |
Country Status (20)
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU217129B (hu) * | 1993-07-16 | 1999-11-29 | EGIS Gyógyszergyár Rt. | Eljárás nagy tisztaságú buspiron gyógyászati hatóanyag előállítására |
| KR950014099A (ko) * | 1993-11-10 | 1995-06-15 | 장기하 | N-(2-피리미딜)피페라지닐 부틸아미드의 제조방법 |
| CN119409681A (zh) * | 2024-03-28 | 2025-02-11 | 北京华素制药股份有限公司 | 一种盐酸丁螺环酮的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1545543B1 (de) * | 1964-07-03 | 1970-01-22 | Astra Apotekarnes Kem Fab | 4-Aminobutinylimide,ihre Salze und Verfahren zu deren Herstellung |
| SE300422B (enrdf_load_stackoverflow) * | 1964-07-03 | 1968-04-29 | Astra Ab | |
| US3354178A (en) * | 1965-04-09 | 1967-11-21 | Sterling Drug Inc | Nu-(4-amino-2-butynyl)-nu-alkylcarboxamides |
| BE759371A (fr) * | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
| JPS6310760A (ja) * | 1986-07-01 | 1988-01-18 | Sumitomo Pharmaceut Co Ltd | イミド誘導体の新規製造法 |
| JPS6310786A (ja) * | 1986-07-01 | 1988-01-18 | Sumitomo Pharmaceut Co Ltd | 新規イミド誘導体およびその製造法 |
-
1988
- 1988-02-23 CH CH675/88A patent/CH677924A5/de not_active IP Right Cessation
- 1988-02-23 PL PL1988270815A patent/PL152958B1/pl unknown
- 1988-02-24 CN CN198888100923A patent/CN88100923A/zh active Pending
- 1988-02-25 KR KR1019880001939A patent/KR880009955A/ko not_active Ceased
- 1988-02-25 GR GR880100108A patent/GR1002245B/el unknown
- 1988-02-25 GB GB8804385A patent/GB2201417B/en not_active Expired - Lifetime
- 1988-02-25 AT AT0047688A patent/AT395851B/de not_active IP Right Cessation
- 1988-02-25 ES ES8800543A patent/ES2009236A6/es not_active Expired
- 1988-02-25 IT IT19545/88A patent/IT1217342B/it active
- 1988-02-25 DE DE3806009A patent/DE3806009C2/de not_active Expired - Fee Related
- 1988-02-25 SE SE8800651A patent/SE8800651L/xx not_active Application Discontinuation
- 1988-02-25 FI FI880895A patent/FI880895A7/fi not_active Application Discontinuation
- 1988-02-25 CS CS122288A patent/CS274423B2/cs unknown
- 1988-02-25 BE BE8800218A patent/BE1001464A3/fr not_active IP Right Cessation
- 1988-02-25 IL IL85545A patent/IL85545A/xx not_active IP Right Cessation
- 1988-02-25 DK DK099388A patent/DK99388A/da not_active Application Discontinuation
- 1988-02-25 NL NL8800484A patent/NL8800484A/nl not_active Application Discontinuation
- 1988-02-25 FR FR888802286A patent/FR2615853B1/fr not_active Expired - Lifetime
- 1988-02-25 YU YU36288A patent/YU46441B/sh unknown
- 1988-02-25 CA CA000559846A patent/CA1300141C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB2201417B (en) | 1990-10-31 |
| GR880100108A (el) | 1988-12-16 |
| CA1300141C (en) | 1992-05-05 |
| GR1002245B (en) | 1996-04-22 |
| NL8800484A (nl) | 1988-09-16 |
| SE8800651D0 (sv) | 1988-02-25 |
| PL152958B1 (en) | 1991-02-28 |
| CH677924A5 (enrdf_load_stackoverflow) | 1991-07-15 |
| FI880895A0 (fi) | 1988-02-25 |
| DK99388A (da) | 1988-08-26 |
| CN88100923A (zh) | 1988-09-28 |
| SE8800651L (sv) | 1988-08-26 |
| IT8819545A0 (it) | 1988-02-25 |
| KR880009955A (ko) | 1988-10-06 |
| FI880895A7 (fi) | 1988-08-26 |
| PL270815A1 (en) | 1989-04-03 |
| DE3806009C2 (de) | 1996-09-12 |
| BE1001464A3 (fr) | 1989-11-07 |
| CS122288A2 (en) | 1990-08-14 |
| DK99388D0 (da) | 1988-02-25 |
| IL85545A (en) | 1992-05-25 |
| YU36288A (en) | 1989-10-31 |
| GB2201417A (en) | 1988-09-01 |
| DE3806009A1 (de) | 1988-09-08 |
| YU46441B (sh) | 1993-10-20 |
| FR2615853A1 (fr) | 1988-12-02 |
| GB8804385D0 (en) | 1988-03-23 |
| IL85545A0 (en) | 1988-08-31 |
| FR2615853B1 (fr) | 1991-01-04 |
| IT1217342B (it) | 1990-03-22 |
| CS274423B2 (en) | 1991-04-11 |
| ATA47688A (de) | 1992-08-15 |
| AT395851B (de) | 1993-03-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20000301 |