EP1820485A1 - Système et dispositif pour extraire des médicaments - Google Patents
Système et dispositif pour extraire des médicaments Download PDFInfo
- Publication number
- EP1820485A1 EP1820485A1 EP20060003098 EP06003098A EP1820485A1 EP 1820485 A1 EP1820485 A1 EP 1820485A1 EP 20060003098 EP20060003098 EP 20060003098 EP 06003098 A EP06003098 A EP 06003098A EP 1820485 A1 EP1820485 A1 EP 1820485A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- ampoule
- reservoir
- adapter
- port
- connection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1468—Containers characterised by specific material properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/2013—Piercing means having two piercing ends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S206/00—Special receptacle or package
- Y10S206/828—Medicinal content
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S215/00—Bottles and jars
- Y10S215/03—Medical
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S604/00—Surgery
- Y10S604/905—Aseptic connectors or couplings, e.g. frangible, piercable
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/9029—With coupling
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/9247—With closure
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/9682—Miscellaneous
Definitions
- the invention relates to a system and apparatus for withdrawing a pharmaceutical from a reservoir.
- liquid pharmaceuticals are often filled in reservoirs or containers, for example, in glass bottles with a few milliliters of content.
- medical personnel can then join.
- adapters may be used between the reservoir and the syringe.
- Different versions of an adapter are for example US Pat. No. 6,591,876 known.
- This adapter has a first container port for coupling to a first container, a second container port for coupling to a second container, a central portion between the two ports, and a cannula which secures the center portion from accidental contact inside the adapter.
- the first container port has elements separated from each other by slots in its side wall to encompass a portion of the first container.
- the second tank connection has in its side wall has two openings to receive on a front part of the second container, two laterally projecting parts similar to a snap closure.
- the adapter has a locking mechanism that holds the adapter in a position in which the middle part is compressed after being coupled to the containers. In another implementation, this compression is not required.
- the middle part is rigid and has two opposite gripping surfaces.
- an adapter is used to make an ampule for an insulin pump, e.g. As an Accu-Chek® insulin pump of Roche Diagnostics GmbH, Germany, to fill with insulin.
- an insulin pump e.g. As an Accu-Chek® insulin pump of Roche Diagnostics GmbH, Germany
- the insulin pump continuously delivers insulin to the body.
- Microprocessors control a motor, the z. B. every three minutes via a threaded rod a stopper moved into an insulin ampule.
- An empty ampoule can be replaced either by the patient himself with insulin or by a finished ampoule.
- Especially devices for self-administration of pharmaceuticals should be easy to use, easy to handle and without much effort.
- the object of the invention to provide a system and a device for removing a liquid pharmaceutical from a container so that a user-friendly type of coupling between the adapter and the ampoule and between the adapter and the reservoir is made possible.
- the apparatus is configured to have at least one detent mechanism having an elastic member.
- the system has an ampule in which a piston movable therein is disposed, and an adapter having in a longitudinal direction a reservoir port and an ampule port for coupling to the ampule.
- the vial port has at least one locking mechanism having an elastic member in a side wall. The elastic member corresponds to a portion of the sidewall that extends along the circumference thereof and merges into the sidewall at opposite ends.
- the adapter for a system for withdrawing a pharmaceutical from a reservoir.
- the adapter has a reservoir port in a longitudinal direction and an ampule port for coupling to an ampule.
- the vial port has at least one locking mechanism having an elastic member in a side wall.
- the elastic member corresponds to a portion of the sidewall that extends along the circumference thereof and merges into the sidewall at opposite ends.
- an insulin pump is just one example of an application in which, in a preliminary step, a pharmaceutical, namely insulin for the treatment of diabetes, is taken from a container for use in another container in an administering device.
- a pharmaceutical namely insulin for the treatment of diabetes
- growth hormones in growth disorders erythropoietin (Epo) in renal insufficiency, or general red blood cell deficiency or ⁇ -interferon in hepatitis or cancer treatment may be used as pharmaceuticals.
- the various ways of carrying out the invention are not limited to liquid pharmaceuticals, although they are frequently removed from a reservoir in medical applications.
- the invention is generally applicable to pharmaceuticals of different viscosities (from liquid to powdered lyophilisate to be dissolved in liquid).
- FIG. 1 shows a schematic representation of an embodiment of a system 1 for removing a pharmaceutical, z.
- the system 1 has an adapter 2 and an ampoule 6 with a piston 8 movable therein.
- the terms "reservoir” and “ampoule” generally refer to a container suitable for receiving a substance is.
- the reservoir 4 and the ampoule 6 may be made of a rigid or rigid material, such as. As plastic, glass, metal or may be made of a material which is flexible or elastic, such. As a film made of plastic or other material.
- the pharmaceutical can be removed from the reservoir 4 and transferred into the ampoule 6.
- the ampoule 6 and the reservoir 4 can be coupled to the adapter 2. This creates a connection between the interior of the reservoir 4 and the interior of the ampoule 6 by means of a hollow needle or cannula.
- a hollow needle or cannula For example, if a patient pulls the piston 8 out of the ampoule 6, the pharmaceutical flows into the ampoule 6.
- the filled ampoule 6 can then be filled, for example , B. be used in an insulin pump.
- a piston rod is removed from the piston 8, so that only one piston stopper remains in the ampoule 6 for sealing purposes.
- the piston 8 is shown in more detail in Figures 5 and 6A-6D.
- Figure 2 shows a side view of an embodiment of the adapter 2.
- the adapter 2 has a reservoir port 10, a central part 12 and an ampoule port 14.
- the reservoir port 10 couples to the reservoir 4 and has approximately the shape of a hollow cylinder, on its outer wall along the circumference several, z. B. three, depressions 16 are located.
- the recesses 16 create on the inner wall bulges, which are shown in Figures 3 and 4.
- the middle part 12 has in the illustrated embodiment, a cylindrical portion which the reservoir port 10 connects to the vial port 14.
- the middle part 12 also has one or more, for example two, ribs 11 or rib elements 11, which project radially outwards and extend outside the cylindrical part between the reservoir connection 10 and the ampoule connection 14.
- the ribs 11 facilitate the gripping or holding of the adapter 2.
- the middle part 12 in the vicinity of the ampoule connection 14 has two opposite openings 18, for example, the patient through the front part of the ampoule 6 (eg Figure 5 shown Luer connector) can see and thus also whether air or the pharmaceutical is in the front part. This makes it easier for the patient at the end of the filling unwanted air in a known manner to remove from the ampoule 6.
- the ampoule connection 14 couples to the ampoule 6 and has approximately the shape of a hollow cylinder whose diameter in the illustrated embodiment increases starting from the middle part 12. In the coupled state of the system, the vial port 14 receives a portion of the Luer port.
- the ampoule connection 14 has in the embodiment shown also in its outer wall two opposite locking mechanisms, each consisting of two slots 22, 24 and an elastic member 20, hereinafter also web 20, exist.
- the slots 22, 24 each produce openings and the elastic member 20 is elastically deformable in the radial direction.
- the ampoule connection 14, in particular the locking mechanisms, are adapted to the front part (eg in the form of a Luer connection) of the ampoule 6 shown in FIG.
- the elastic member 20 and the slot are part of a locking mechanism. Also in this embodiment, the elastic element 20 is elastically deformable in the radial direction.
- FIG. 3 shows a plan view of the adapter 2 shown in FIG. 2, so that the reservoir connection 10 and a hollow needle 26 or cannula 26 are visible.
- the outer wall of the reservoir connection 10 has a shape deviating from a circle.
- the outer wall another, z. B. have a circular shape.
- the shape shown in FIG. 3 deviating from a circle results for example from a flattening of a circular outer wall in the region of the three recesses 16, for example by forming and by a shaping process.
- the depressions 16 are distributed uniformly along the circumference of the outer wall and create bulges in the interior of the reservoir connection 10.
- the non-circular shape allows the inclusion of reservoirs 4, which have slightly different diameters.
- the shape approximates to an optimal circle.
- a difference between the non-circular shape and the shape of an optimal circle can be used as a deformation to compensate for different diameters.
- the bulges serve to retain the reservoir 4 in the adapter 2.
- a circular bump 28 surrounds the cannula 26.
- the diameter of the bump 28 is adapted to the outer diameter of one end of the reservoir front part.
- the bulge 28 serves for length compensation of different reservoirs 4, since the bulge 28 can dip into the elastic septum (piercing membrane).
- FIG. 4 shows a perspective view of the adapter 2, in the inter alia, one of the three elements 11 and one of the two locking mechanisms are visible.
- FIG. 5 shows a schematic representation of the piston 8 arranged in the ampoule 6. The ampoule 6 is shown in FIG. 5 only in its front region.
- the web 20 corresponds to an elongated portion of the outer wall, which extends along the circumference thereof and parallel to the slots 22, 24 and merges at its ends into the outer wall.
- the slot 22 adjoins a longitudinal side of the web 20, and in the direction of the ampoule 6, the slot 24 adjoins a further longitudinal side of the web 20.
- the web 20 can be curved into the interior of the ampoule connection 14 be.
- the adapter 2 is made in one embodiment of polypropylene (PP), which is elastically deformable. The web 20 is therefore also elastic, especially in the radial direction.
- the front part of the ampoule 6 is based in one embodiment on a (male) Luer connector 30, which is equipped with a collar part 32.
- the collar part 32 projects substantially perpendicularly from a longitudinal axis of the Luer connection 30.
- the collar part 32 has two circular parts 36, 38 which are separated in the direction of the longitudinal axis by four struts 34 from each other. This results in between the parts 36, 38 four separate cavities 40th
- the front part of the ampoule 6 is pushed into the ampoule connection 14 and the ampoule 6 and the adapter 2 are pressed against each other.
- the circular collar part 36 initially pushes the webs 20 outwards.
- the two webs 20 noticeably engage in the corresponding cavities 40.
- the webs 20 encounter struts 34, the webs 20 can be positioned by slight axial rotation of the ampoule 6 and / or the adapter 2 so that they meet cavities 40 and the webs 20 can engage. In the detented state penetrates the circular collar portion 36 in the openings 22, and the webs 20 relax in their original state and thus ensure the coupling.
- the patient may preferentially pull the ampule 6 and the adapter 2 apart in conjunction with an axial rotation of the ampule 6 and / or the adapter 2.
- the struts 34 push the webs 20 outwards, whereby the ampoule 6 and the adapter 2 can be separated from each other with relatively little effort.
- FIGS 6A and 6B are schematic illustrations of the piston 8 having a piston rod 46 and a piston plug 42.
- FIG. 6B shows a longitudinal section through the piston 8.
- the piston stopper 42 is threadably connected to a front end of the piston rod 46 and has two sealing rings 44. Each sealing ring 44 lies in a groove which extends along the circumference of the piston stopper 42.
- the front end of the piston rod 46 has a screw part 52, which is screwed into a blind hole of the piston butt 42.
- the screw part 52 has an external thread which is adapted to a corresponding internal thread of the blind hole.
- the piston rod 46 has an ergonomically shaped handle 48 on which the patient can grip and pull the piston 8.
- the ergonomically shaped handle 48 connects seamlessly to the remaining part of the piston rod 46.
- the handle 48 is generally designed so that the patient can grasp it comfortably and naturally with two (e.g., between thumb and forefinger) or three fingers (eg, with thumb, forefinger, and middle finger). In particular, it offers the patient a relatively large grip surface. Edges that some patients may find uncomfortable or even painful are largely avoided.
- Figures 6C and 6D are schematic representations of the piston rod 46 without the piston plug 42.
- the screw member 52 has a gap 50 which extends extends along the longitudinal axis and divides the screw member 52 into two parts.
- the two parts are elastic and can be pressed towards each other, for example, when the piston plug 42 is screwed.
- the outer diameter of the screw part 52 is greater by a predetermined amount than the diameter of the internal thread of the piston stopper 42.
- the elasticity of the separated by the gap 50 parts compensates for the specified difference in diameter and any existing manufacturing tolerances, d. H. the piston plug 42 compresses the parts according to its internal thread. The parts thus also press against the internal thread of the piston stopper 42, whereby a play-free connection is formed and the piston rod 46 and the piston stopper 42 are held together better. This is especially an advantage if the patient at the end of the filling process with a finger against the wall of the ampoule 6 knocks, so that possibly in the ampoule 6 existing air bubbles rise upwards.
- This screw is designed so that the torque for releasing the piston rod 46 is smaller than the torque for rotating the piston plug 42 in the ampoule 6. This ensures that the piston rod 46 can unscrew without the piston plug 42 thereby rotates.
- the above described embodiments of a system and apparatus for withdrawing a pharmaceutical from a reservoir 4 generally facilitate the removal of the pharmaceutical.
- the filling of an empty ampoule 6 is made easier, especially for the patient.
- the locking mechanism and the distributed cavities on the ampoule increase the likelihood that when coupling the ampoule 6 to the adapter 2, the web 20 snaps into a cavity 40.
- the patient on the adapter 2 and / or on the ampoule. 6 pulls, possibly with a rotary motion.
- the elastic web 20 then releases the collar part 32.
- openings 18 and the slotted screw portion 52 are the openings 18 and the slotted screw portion 52.
- the openings 18 on the adapter 2 facilitate the removal of unwanted air from the ampule 6 at the end of the filling process. Since the patient may knock on the ampoule 6 and / or the piston rod 46 under certain circumstances, it is advantageous that the slotted screw part 52 is firmly seated in the piston stopper 42 and does not come off unintentionally.
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Manipulator (AREA)
- Vending Machines For Individual Products (AREA)
- Centrifugal Separators (AREA)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE200650005333 DE502006005333D1 (de) | 2006-02-16 | 2006-02-16 | System und Vorrichtung zum Entnehmen von Pharmazeutika |
EP20060003098 EP1820485B1 (fr) | 2006-02-16 | 2006-02-16 | Système et dispositif pour extraire des médicaments |
AT06003098T ATE447923T1 (de) | 2006-02-16 | 2006-02-16 | System und vorrichtung zum entnehmen von pharmazeutika |
DK06003098T DK1820485T3 (da) | 2006-02-16 | 2006-02-16 | Anlæg og apparat til udtagning af piller |
CA 2571909 CA2571909A1 (fr) | 2006-02-16 | 2006-12-21 | Systeme et dispositif pour retirer des produits pharmaceutiques |
JP2007019066A JP2007216008A (ja) | 2006-02-16 | 2007-01-30 | 医薬品を移し替えるためのシステム及びデバイス |
US11/675,337 US7435246B2 (en) | 2006-02-16 | 2007-02-15 | System and device for removing pharmaceutical products |
CN2007100059607A CN101023904B (zh) | 2006-02-16 | 2007-02-15 | 用于取出药品的系统和装置 |
HK08101681A HK1111077A1 (en) | 2006-02-16 | 2008-02-15 | System and device for removing pharmaceutical products |
US12/120,527 US8257336B2 (en) | 2006-02-16 | 2008-05-14 | System and device for removing pharmaceutical products |
US12/207,747 US8187248B2 (en) | 2006-02-16 | 2008-09-10 | System and device for removing pharmaceutical products |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20060003098 EP1820485B1 (fr) | 2006-02-16 | 2006-02-16 | Système et dispositif pour extraire des médicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1820485A1 true EP1820485A1 (fr) | 2007-08-22 |
EP1820485B1 EP1820485B1 (fr) | 2009-11-11 |
Family
ID=36658851
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20060003098 Not-in-force EP1820485B1 (fr) | 2006-02-16 | 2006-02-16 | Système et dispositif pour extraire des médicaments |
Country Status (9)
Country | Link |
---|---|
US (3) | US7435246B2 (fr) |
EP (1) | EP1820485B1 (fr) |
JP (1) | JP2007216008A (fr) |
CN (1) | CN101023904B (fr) |
AT (1) | ATE447923T1 (fr) |
CA (1) | CA2571909A1 (fr) |
DE (1) | DE502006005333D1 (fr) |
DK (1) | DK1820485T3 (fr) |
HK (1) | HK1111077A1 (fr) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2258333A1 (fr) | 2009-06-02 | 2010-12-08 | F. Hoffmann-La Roche AG | Dispositif de remplissage de réservoir flexible |
EP2319477A1 (fr) | 2009-11-06 | 2011-05-11 | F. Hoffmann-La Roche AG | Dispositif de remplissage d'un conteneur de réservoir flexible dans une chambre à pression négative |
WO2011069635A2 (fr) | 2009-12-09 | 2011-06-16 | Roche Diagnostics Gmbh | Procédé de remplissage d'un récipient avec un médicament liquide |
EP2383495A1 (fr) * | 2010-04-28 | 2011-11-02 | Famat S.A. | Dispositif de prélèvement d'échantillons de produit |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
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IL114960A0 (en) | 1995-03-20 | 1995-12-08 | Medimop Medical Projects Ltd | Flow control device |
IL161660A0 (en) | 2004-04-29 | 2004-09-27 | Medimop Medical Projects Ltd | Liquid drug delivery device |
EP1919432B1 (fr) | 2005-08-11 | 2011-10-19 | Medimop Medical Projects Ltd. | Dispositifs de transfert de médicament liquide pour un encliquetage correct à sûreté intégrée sur des fioles médicinales |
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
EP2526920B8 (fr) | 2006-05-25 | 2015-08-26 | Bayer Healthcare LLC | Dispositif de reconstitution |
IL182605A0 (en) | 2007-04-17 | 2007-07-24 | Medimop Medical Projects Ltd | Fluid control device with manually depressed actuator |
JP2010538744A (ja) | 2007-09-18 | 2010-12-16 | メディモップ・メディカル・プロジェクツ・リミテッド | 薬剤混合注射装置 |
IL186290A0 (en) | 2007-09-25 | 2008-01-20 | Medimop Medical Projects Ltd | Liquid drug delivery devices for use with syringe having widened distal tip |
CA2649160A1 (fr) * | 2009-01-09 | 2010-07-09 | Duoject Medical Systems Inc. | Dispositif de transfert de fluide |
USD641080S1 (en) | 2009-03-31 | 2011-07-05 | Medimop Medical Projects Ltd. | Medical device having syringe port with locking mechanism |
USD616984S1 (en) | 2009-07-02 | 2010-06-01 | Medimop Medical Projects Ltd. | Vial adapter having side windows |
USD630732S1 (en) | 2009-09-29 | 2011-01-11 | Medimop Medical Projects Ltd. | Vial adapter with female connector |
IL201323A0 (en) | 2009-10-01 | 2010-05-31 | Medimop Medical Projects Ltd | Fluid transfer device for assembling a vial with pre-attached female connector |
IL202070A0 (en) | 2009-11-12 | 2010-06-16 | Medimop Medical Projects Ltd | Inline liquid drug medical device |
IL202069A0 (en) | 2009-11-12 | 2010-06-16 | Medimop Medical Projects Ltd | Fluid transfer device with sealing arrangement |
EP2512399B1 (fr) | 2010-02-24 | 2015-04-08 | Medimop Medical Projects Ltd. | Ensemble de transfert de fluide avec mécanisme d'aération |
JP5709905B2 (ja) | 2010-02-24 | 2015-04-30 | メディモップ・メディカル・プロジェクツ・リミテッド | ベント付きバイアルアダプタを含む液剤移送デバイス |
USD655017S1 (en) | 2010-06-17 | 2012-02-28 | Yukon Medical, Llc | Shroud |
CN102371195B (zh) * | 2010-08-23 | 2013-08-21 | 中国科学院空间科学与应用研究中心 | 一种用于样品安瓿的锁紧机构 |
USD669980S1 (en) | 2010-10-15 | 2012-10-30 | Medimop Medical Projects Ltd. | Vented vial adapter |
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3023925A (en) * | 1959-09-21 | 1962-03-06 | Fred D Sher | Container for packaging merchandise |
US20020095121A1 (en) * | 2000-11-08 | 2002-07-18 | Norton Paul H. | Syringe safety device |
US20020189712A1 (en) * | 1999-11-05 | 2002-12-19 | Medtronic Minimed, Inc. | Needle safe transfer guard |
US20030070726A1 (en) * | 2001-10-11 | 2003-04-17 | Kjell Andreasson | Method and assembly for fluid transfer |
US20040040965A1 (en) * | 2002-08-28 | 2004-03-04 | The Procter & Gamble Company | Containment vessel |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3080866A (en) * | 1961-07-07 | 1963-03-12 | Friedman Benjamin | Hypodermic needle |
US3826260A (en) | 1971-12-27 | 1974-07-30 | Upjohn Co | Vial and syringe combination |
US4249341A (en) | 1979-08-27 | 1981-02-10 | Huegli Ronald W | Package for sprouts |
NO157085C (no) * | 1986-01-07 | 1988-01-20 | Chr Sandsdalen | Anordning ved injeksjonssprte for engangsbruk. |
AU2717988A (en) * | 1987-11-25 | 1989-06-14 | Gudmar Olovson | A syringe |
DE8809014U1 (fr) * | 1988-07-14 | 1988-09-08 | Metallform Gmbh, 5880 Luedenscheid, De | |
US5094148A (en) * | 1989-05-08 | 1992-03-10 | Habley Medical Technology Corporation | Piston stem insert for a carpule based piston |
US4998713A (en) * | 1990-01-10 | 1991-03-12 | Vaillancourt Vincent L | Needle connector |
US6146362A (en) * | 1993-08-27 | 2000-11-14 | Baton Development, Inc. | Needleless IV medical delivery system |
US5460617A (en) * | 1994-07-28 | 1995-10-24 | Abbott Laboratories | Syringe plunger with intermediate pushing surface |
US5688252A (en) * | 1994-09-30 | 1997-11-18 | Takeda Chemical Industries, Ltd. | Syringe |
FR2726768A1 (fr) * | 1994-11-14 | 1996-05-15 | Debiotech Sa | Dispositif de seringue fixable sur un flacon |
US5833213A (en) | 1995-12-29 | 1998-11-10 | Rymed Technologies, Inc. | Multiple dose drug vial adapter for use with a vial having a pierceable septum and a needleless syringe |
CA2211629A1 (fr) | 1996-09-17 | 1998-03-17 | Bernard Sams | Ensemble-raccord pour fiole a medicaments |
US6402207B1 (en) * | 1997-06-09 | 2002-06-11 | Qd Enterprises, Llc | Safety indexed medical connectors |
US6159192A (en) | 1997-12-04 | 2000-12-12 | Fowles; Thomas A. | Sliding reconstitution device with seal |
US6568434B2 (en) * | 1998-02-04 | 2003-05-27 | Omrix Biopharmaceuticals S.A. | Receiver cup for a vessel housing a medicinal substance |
US6957745B2 (en) * | 1998-04-20 | 2005-10-25 | Becton, Dickinson And Company | Transfer set |
US6113583A (en) * | 1998-09-15 | 2000-09-05 | Baxter International Inc. | Vial connecting device for a sliding reconstitution device for a diluent container |
JP2000140103A (ja) * | 1998-11-05 | 2000-05-23 | Daikyo Seiko Ltd | 注射器用プランジャ |
DE29915878U1 (de) * | 1999-09-09 | 2000-10-26 | Disetronic Licensing Ag | Vorrichtung zur Umfüllung von Arzneimitteln und Kanülenanordnung |
FR2817465B1 (fr) | 2000-12-06 | 2003-04-25 | Technoflex Sa | Dispositif de reconstitution notamment pour le melange de substances dans le domaine medical |
GB0029752D0 (en) * | 2000-12-06 | 2001-01-17 | Lilly Industries Ltd | A protective container and a package comprising a protective container |
DE10142450C1 (de) * | 2001-08-31 | 2003-06-18 | Aventis Behring Gmbh | Vorrichtung zum Zusammenführen von Komponenten unter sterilen Bedingungen |
FR2853830B1 (fr) * | 2003-04-15 | 2006-05-26 | Frederic Senaux | Capuchon de transfert a moyen d'etancheite |
US6948522B2 (en) * | 2003-06-06 | 2005-09-27 | Baxter International Inc. | Reconstitution device and method of use |
US20060184103A1 (en) * | 2005-02-17 | 2006-08-17 | West Pharmaceutical Services, Inc. | Syringe safety device |
US7862539B2 (en) | 2006-06-01 | 2011-01-04 | Codan Us Corporation | System and method for infusing toxins using safety set, connect set and cyto admin set |
-
2006
- 2006-02-16 EP EP20060003098 patent/EP1820485B1/fr not_active Not-in-force
- 2006-02-16 AT AT06003098T patent/ATE447923T1/de active
- 2006-02-16 DK DK06003098T patent/DK1820485T3/da active
- 2006-02-16 DE DE200650005333 patent/DE502006005333D1/de active Active
- 2006-12-21 CA CA 2571909 patent/CA2571909A1/fr not_active Abandoned
-
2007
- 2007-01-30 JP JP2007019066A patent/JP2007216008A/ja active Pending
- 2007-02-15 US US11/675,337 patent/US7435246B2/en active Active
- 2007-02-15 CN CN2007100059607A patent/CN101023904B/zh not_active Expired - Fee Related
-
2008
- 2008-02-15 HK HK08101681A patent/HK1111077A1/xx not_active IP Right Cessation
- 2008-05-14 US US12/120,527 patent/US8257336B2/en active Active
- 2008-09-10 US US12/207,747 patent/US8187248B2/en active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3023925A (en) * | 1959-09-21 | 1962-03-06 | Fred D Sher | Container for packaging merchandise |
US20020189712A1 (en) * | 1999-11-05 | 2002-12-19 | Medtronic Minimed, Inc. | Needle safe transfer guard |
US6591876B2 (en) | 1999-11-05 | 2003-07-15 | Medtronic Minimed, Inc. | Needle safe transfer guard |
US20020095121A1 (en) * | 2000-11-08 | 2002-07-18 | Norton Paul H. | Syringe safety device |
US20030070726A1 (en) * | 2001-10-11 | 2003-04-17 | Kjell Andreasson | Method and assembly for fluid transfer |
US20040040965A1 (en) * | 2002-08-28 | 2004-03-04 | The Procter & Gamble Company | Containment vessel |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2258333A1 (fr) | 2009-06-02 | 2010-12-08 | F. Hoffmann-La Roche AG | Dispositif de remplissage de réservoir flexible |
US8602067B2 (en) | 2009-06-02 | 2013-12-10 | Roche Diagnostics International Ag | Devices and methods for filling a flexible liquid medicament container with liquid from a liquid medicament reservoir |
US9352865B2 (en) | 2009-06-02 | 2016-05-31 | Roche Diagnostics International Ag | Devices and methods for filling a flexible liquid medicament container with liquid from a liquid medicament reservoir |
EP2319477A1 (fr) | 2009-11-06 | 2011-05-11 | F. Hoffmann-La Roche AG | Dispositif de remplissage d'un conteneur de réservoir flexible dans une chambre à pression négative |
WO2011069635A2 (fr) | 2009-12-09 | 2011-06-16 | Roche Diagnostics Gmbh | Procédé de remplissage d'un récipient avec un médicament liquide |
US9089647B2 (en) | 2009-12-09 | 2015-07-28 | Roche Diagnostics International Ag | Apparatuses, systems, and methods for filling a container with a liquid drug |
EP2383495A1 (fr) * | 2010-04-28 | 2011-11-02 | Famat S.A. | Dispositif de prélèvement d'échantillons de produit |
Also Published As
Publication number | Publication date |
---|---|
US20090012492A1 (en) | 2009-01-08 |
CN101023904A (zh) | 2007-08-29 |
DK1820485T3 (da) | 2010-03-08 |
HK1111077A1 (en) | 2008-08-01 |
JP2007216008A (ja) | 2007-08-30 |
US8257336B2 (en) | 2012-09-04 |
US20070191764A1 (en) | 2007-08-16 |
EP1820485B1 (fr) | 2009-11-11 |
ATE447923T1 (de) | 2009-11-15 |
DE502006005333D1 (de) | 2009-12-24 |
US7435246B2 (en) | 2008-10-14 |
US20080287886A1 (en) | 2008-11-20 |
CN101023904B (zh) | 2012-02-01 |
CA2571909A1 (fr) | 2007-08-16 |
US8187248B2 (en) | 2012-05-29 |
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