EP1015335B1 - Mehrkammerausgabebehälter zum getrennten lagern zumindest zweier komponenten - Google Patents

Mehrkammerausgabebehälter zum getrennten lagern zumindest zweier komponenten Download PDF

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Publication number
EP1015335B1
EP1015335B1 EP98905468A EP98905468A EP1015335B1 EP 1015335 B1 EP1015335 B1 EP 1015335B1 EP 98905468 A EP98905468 A EP 98905468A EP 98905468 A EP98905468 A EP 98905468A EP 1015335 B1 EP1015335 B1 EP 1015335B1
Authority
EP
European Patent Office
Prior art keywords
container
occlusion
activation
dispensing
occlusion means
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP98905468A
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English (en)
French (fr)
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EP1015335A1 (de
Inventor
Antoine Aneas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biodome SAS
Original Assignee
Biodome SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biodome SAS filed Critical Biodome SAS
Publication of EP1015335A1 publication Critical patent/EP1015335A1/de
Application granted granted Critical
Publication of EP1015335B1 publication Critical patent/EP1015335B1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
    • B65D25/02—Internal fittings
    • B65D25/04—Partitions
    • B65D25/08—Partitions with provisions for removing or destroying, e.g. to facilitate mixing of contents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S215/00—Bottles and jars
    • Y10S215/08—Mixing

Definitions

  • the present invention relates to a container multi-chamber distributor, for the storage of at least two substances that must be stored in a way separate, the extemporaneous mixture of these, and the distribution of the mixture of these substances.
  • the current invention will be more particularly described with respect to a two-chamber dropper bottle containing sterile during storage, for example, a powder lyophilized in a first chamber, and a liquid in a second chamber, these two substances then being mixed extemporaneously in the container, and the mixture then being dispensed.
  • This disc is arranged perpendicular to the container body, and is larger in diameter than the internal diameter of the container body. Thus the disc is held in place by the elastic grip of the container body on the peripheral edge thereof.
  • Dispensing means are also provided in the vicinity of the opening end of the container body, sealingly closing said opening, and take the form of an injection needle. Before activation, that is to say during storage, the two liquids are therefore separated in a sealed manner by the disc.
  • the activation of the dispensing container is done by a movement of the disc driven by the pressure of the hand and thumb in an alternating movement on the body of the container. The disc is thus caused to fall into the bottom of the tube, and the two solutions can mix. The mixture is then distributed by injection into the body through the needle.
  • the present invention proposes to solve this problem in providing a dispenser container multi-chamber for sealed storage, before activation, and distribution in the mixed state, after activation, at least two substances, including a liquid and a lyophilized powder, said container comprising a body of substantially tubular container, of a material elastically deformable, having one end of bottom, and an opening end, and at least one means occlusion with a continuous peripheral edge, arranged inside the container body, between the bottom end and the opening end, closing said body sealingly along its said edge peripheral, and separating said body into at least two chambers, for the two substances respectively, the container further comprising dispensing means substances in a mixed state, arranged in the vicinity of the opening end, and closing it so waterproof.
  • the dispensing container according to the present invention is more particularly characterized in that before activation of the container, the occlusion means is arranged obliquely in the body substantially tubular, and includes at least a first zone partially tearable device under the effect of transverse finger activation pressure, and at least a second peripheral zone, different from the first zone, tearproof under the effect of said pressure activation, keeping the occlusion device in place in the tubular body after activation.
  • This solution has the advantage that the user pressure is reduced to a minimum, because it is possible to activate the medium occlusion, and therefore mix the substances contained in the different rooms, by a simple light finger pressure on the container body.
  • the tear-proof zones allow by means occlusion of letting substances pass through a room to the other, while avoiding that the means of occlusion block the exit of the mixture during its distribution by the means of distribution.
  • the occlusion means can be constituted by the same material as that of the substantially tubular body.
  • the first peripheral zone of the occlusion means can be present as part of the peripheral edge, reduced thickness compared to the central thickness said means of occlusion.
  • the second peripheral zone of the occlusion means may comprise two bridges of material, constituting between them an axis of rotation for said means occlusion, during activation of the container, said axis of rotation being arranged perpendicular to the direction of the transverse activation pressure of fingers.
  • the means of occlusion can be present substantially in the form of a disc.
  • the body substantially tubular has, on its outer surface, a gripping recess for a finger above the means occlusion, and a gripping recess for a finger below said occlusion means.
  • the container can advantageously have a removable activation blocking sleeve substantially tubular container body, of a material not elastically deformable, which surrounds said body at less at the level of the means of occlusion.
  • the distribution means are integrated into or mounted on the container body, and are constituted by a nose of substantially frustoconical shape fitted with a dropper.
  • the container may include a cap protection of distribution means, removable, comprising at least one elastic gripping element with the container body and / or with the distribution means, and a plug member of said means distribution, arranged inside the cap.
  • a container distributor 1 multi-room comprises a container body substantially tubular 4 of a deformable material elastically, therefore relatively flexible, for example in low density polyethylene or polypropylene.
  • the body 4 has a bottom end 5, closed for example by a plug Sa, and an opening end 6, as well as a occlusion means 7, which separates the body 4 in two chambers 9,10 in a sealed manner.
  • body 4 can have, on its outer surface, a recess 16 of gripping for a finger above the occlusion means 7, and a gripping recess 17 for a finger below said occlusion means 7.
  • the chamber 9 contains a liquid 2, and the chamber 10 a powder 3, by freeze-dried example, but it is understood that both substances can also be combinations, for example of two or more liquids, or two powders, or that the chamber 10 contains a liquid 2 and the chamber 9 contains a powder 3.
  • the container 1 comprises moreover means 11 for distributing substances 2,3 in the mixed state, arranged near the end opening 6, and sealingly closing it, and which will be described in more detail below.
  • the means occlusion 7 has a continuous peripheral edge 8, disposed inside the container body 4, between the bottom end 5 and the opening end 6, closing the body 4 tightly along its edge peripheral 8.
  • the two substances do not cannot come into contact with each other, and are actually stored tightly. This allows store in the same container for a long time substances in a separate state that are relatively unstable when they come into contact with one the other, which is the case for example of several drugs.
  • the occlusion means 7 is arranged obliquely in the body 4, and includes a first peripheral zone 12 partially tearable under pressure transverse activation of the fingers, and a second zone 13 peripheral, different from the first zone 12, tearproof under the effect of the activation pressure, now the occlusion means 7 in place in the body 4 tubular after activation.
  • the means occlusion 7 is made of the same material as that of the substantially tubular body, so for example in low density polyethylene or polypropylene.
  • the means occlusion occurs substantially in the form of a disc, for example circular or elliptical, but this shape can of course vary depending on the shape circumferential of the container body 4, and can by example be polygonal.
  • the first peripheral zone 12 of the disk 7 is present in the form of a part of the peripheral edge 8, thickness reduced compared to the central thickness of the disk 7, and the second peripheral zone 13 comprises two material bridges, for example thicker than the thickness of the disc 7, constituting between them an axis of rotation 15 for this one, when activating the container 1.
  • Figure 5 which is a sectional view along line V-V of Figure 4, the axis of rotation 15 is arranged perpendicular to the direction transverse activation pressure of the fingers, so as to force the rotation of the disc to take place in the direction of the activation force.
  • the container includes means for distribution 11, in particular integrated into or mounted on the body 4, for example by irreversible latching and waterproof or by welding or molding in one piece.
  • the means of distribution are constituted by a nose 19 of substantially frustoconical shape fitted with a dropper 20, fitted at its end proximal, i.e. at the tip opening 6 of body 4, of an annular flange 24 fixed for example by welding to the body 4 along the perimeter of this last.
  • the distribution means 11 can be also covered by a cap 21, comprising at its inside a plug 23, adapted to receive and seal the dropper 20 of the nose 19, and gripping elements elastic 22 with the body 4 of container 1 and / or with the distribution means 11.
  • These elastic gripping elements can be formed, for example, by teeth elastics that snap reversibly onto and around the annular flange 24 means for distribution 11.
  • this may further include a sleeve 18 removable body activation lock 4, in one elastically non-deformable material, which surrounds said body 4 at least at the level of the occlusion means 7.
  • the sleeve 18 is preferably made of a more rigid as that constituting the body 4, for example in high density polyethylene or polypropylene, so that resist pressure from the fingers or the hand on the container. As illustrated in Figure 1, this sleeve 18 covers, starting from the bottom end 5, the gripping recesses 16,17 and the body 4 up to disc level 7, effectively preventing any inadvertent activation by the user.
  • the sleeve 18 Before activation, the sleeve 18 is in place, as well as the cap 21 (see figure 2). The sleeve 18 is then removed from below, exposing the body 4 of the container, and the gripping recesses 16,17. A pressure light activation is exerted on the recesses by the fingers of the user, which causes tearing of the peripheral zone 12 at this pressure, the disc 7 held by the bridges 13 entering in rotation from so as to create an opening on either side of the axis 15, allowing the substances to be mixed (cf. Figures 3 and 4), either by shaking the container, or by repeatedly pressing again with your fingers on the container body. Then the cap is removed, and the mixture can be dispensed by means of distribution 11 formed by the nose 19 and the count drop 20. After dispensing the mixture, the cap can be snapped onto the distribution means 11, until further use.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Package Specialized In Special Use (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Closures For Containers (AREA)
  • External Artificial Organs (AREA)

Claims (9)

  1. Verteilerbehälter (1) mit mehreren Kammern für die dichte Aufbewahrung vor einer Betätigung und die Verteilung im gemischten Zustand nach einer Betätigung von mindestens zwei Substanzen (2, 3), insbesondere einer Flüssigkeit und eines lyophilisierten Pulvers, wobei der Behälter einen im wesentlichen rohrförmigen Behälterkörper (4) aus einem elastisch verformbaren Material, der ein Bodenende (5) und ein Öffnungsende (6) besitzt, und mindestens eine Verschlußeinrichtung (7) aufweist, die einen durchgehenden Umfangsrand (8) besitzt, im Inneren des Behälterkörpers (4) zwischen dem Bodenende (5) und dem Öffnungsende (6) angeordnet ist, den Körper (4) entlang seines Umfangsrande (8) dicht verschließt und den Körper (4) in mindestens zwei Kammern (9, 10) für die beiden Substanzen (2 bzw. 3) unterteilt, wobei der Behälter (1) außerdem eine Verteilereinrichtung (11) für die Substanzen (2, 3) in gemischtem Zustand aufweist, die in der Nähe des Öffnungsendes (6) angeordnet sind und diese dicht verschießen,
    dadurch gekennzeichnet, daß vor einer Betätigung des Behälters (1) die Verschlußeinrichtung (7) in dem im wesentlichen rohrförmigen Körper (4) schräg angeordnet ist und mindestens eine erste Umfangszone (12), die unter Einwirkung eines quer gerichteten Betätigungsdrucks der Finger teilweise zerreißbar ist, und mindestens eine von der ersten Zone (12) verschiedene, unter der Einwirkung des Betätigungsdrucks nicht zerreißbare zweite Umfangszone (13) aufweist, die die Verschlußeinrichtung (7) nach einer Betätigung an ihrem Platz in dem rohrförmigen Körper (4) hält.
  2. Verteilerbehälter (1) mit mehreren Kammern nach Anspruch 1,
    dadurch gekennzeichnet, daß die Verschlußeinrichtung (7) aus dem gleichen Material wie dem des im wesentlichen rohrförmigen Körpers besteht.
  3. Verteilerbehälter (1) mit mehreren Kammern nach Anspruch 2,
    dadurch gekennzeichnet, daß die erste Umfangszone (12) der Verschlußeinrichtung (7) die Form eines Teils des Umfangsrandes (8) mit einer im Verhältnis zu der Dicke in der Mitte des Verschlußeinrichtung (7) verringerten Dicke aufweist.
  4. Verteilerbehälter (1) mit mehreren Kammern nach einem der Ansprüche 1 bis 3,
    dadurch gekennzeichnet, daß die zweite Umfangszone (13) der Verschlußeinrichtung (2) zwei Materialbrücken aufweist, die bei der Betätigung des Behälters (1) miteinander eine Drehachse (15) für die Verschlußeinrichtung (7) bilden, wobei die Drehachse (15) senkrecht zur Richtung des quer gerichteten Betätigungsdrucks der Finger angeordnet ist.
  5. Verteilerbehälter (1) mit mehreren Kammern nach einem der Ansprüche 1 bis 4,
    dadurch gekennzeichnet, daß die Verschlußeinrichtung (7) im wesentlichen die Form einer Scheibe hat.
  6. Verteilerbehälter mit mehreren Kammern nach einem der Ansprüche 1 bis 5,
    dadurch gekennzeichnet, daß der im wesentlichen rohrförmige Körper (4) auf seiner Außenfläche eine Greifmulde (16) für einen Finger über der Verschlußeinrichtung (7) und eine Greifmulde (17) für einen Finger unter der Verschlußeinrichtung (7) aufweist.
  7. Verteilerbehälter (1) mit mehreren Kammern nach einem der Ansprüche 1 bis 6,
    dadurch gekennzeichnet, daß er außerdem eine abnehmbare Hülse (18) für die Blockierung einer Betätigung des im wesentlichen rohrförmigen Behälterkörpers (4) aus einem nicht elastisch verformbaren Material aufweist, die den Körper (4) zumindest in Höhe der Verschlußeinrichtung (7) umgibt.
  8. Verteilerbehälter (1) mit mehreren Kammern nach einem der Ansprüche 1 bis 7,
    dadurch gekennzeichnet, daß die Verteilereinrichtung (11) In den Körper (4) des Behälters (1) integriert oder an ihm angebracht ist und aus einer im wesentlichen kegelstumpfförmigen Nase (19) besteht, die mit einem Tropfenzähler (20) versehen ist.
  9. Verteilerbehälter (1) mit mehreren Kammern nach einem der Ansprüche 1 bis 8,
    dadurch gekennzeichnet; daß er außerdem eine abnehmbare Kappe (21) zum Schutz der Verteilereinrichtung, die mindestens ein elastisches Element (22) zum Angreifen am Körper (4) des Behälters (1) und/oder an der Verteilereinrichtung (11) aufweist und ein einen Pfropfen (23) für die Verteilereinrichtung(11) bildendes Element aufweist, das im Inneren der Kappe (21) angeordnet ist.
EP98905468A 1997-02-07 1998-01-30 Mehrkammerausgabebehälter zum getrennten lagern zumindest zweier komponenten Expired - Lifetime EP1015335B1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9701633A FR2759348B1 (fr) 1997-02-07 1997-02-07 Recipient distributeur multichambre pour le stockage d'au moins deux substances, le melange extemporane de celle-ci et la distribution du melange
FR9701633 1997-02-07
PCT/FR1998/000177 WO1998034842A1 (fr) 1997-02-07 1998-01-30 Recipient distributeur multichambre pour le stockage d'au moins deux substances, le melange extemporane de celles-ci et la distribution du melange

Publications (2)

Publication Number Publication Date
EP1015335A1 EP1015335A1 (de) 2000-07-05
EP1015335B1 true EP1015335B1 (de) 2002-11-20

Family

ID=9503627

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98905468A Expired - Lifetime EP1015335B1 (de) 1997-02-07 1998-01-30 Mehrkammerausgabebehälter zum getrennten lagern zumindest zweier komponenten

Country Status (12)

Country Link
US (1) US6189688B1 (de)
EP (1) EP1015335B1 (de)
JP (1) JP3294858B2 (de)
CN (1) CN1080685C (de)
AT (1) ATE228087T1 (de)
AU (1) AU724953B2 (de)
BR (1) BR9807555A (de)
CA (1) CA2278668A1 (de)
DE (1) DE69809572T2 (de)
FR (1) FR2759348B1 (de)
RU (1) RU2184058C2 (de)
WO (1) WO1998034842A1 (de)

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WO2016136862A1 (ja) * 2015-02-27 2016-09-01 東洋製罐株式会社 混合容器及び内容物入り混合容器並びに内容物入り混合容器の製造方法
CN108408239A (zh) * 2018-03-21 2018-08-17 永德利硅橡胶科技(深圳)有限公司 旋转瓶盖以及水瓶
JP6603364B1 (ja) * 2018-05-16 2019-11-06 株式会社テックスイージー 容器入り飲料温度調節装置
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Also Published As

Publication number Publication date
FR2759348B1 (fr) 1999-04-16
CN1249723A (zh) 2000-04-05
DE69809572D1 (de) 2003-01-02
WO1998034842A1 (fr) 1998-08-13
DE69809572T2 (de) 2003-09-25
AU6104298A (en) 1998-08-26
EP1015335A1 (de) 2000-07-05
ATE228087T1 (de) 2002-12-15
CN1080685C (zh) 2002-03-13
BR9807555A (pt) 2000-02-01
AU724953B2 (en) 2000-10-05
JP2001509759A (ja) 2001-07-24
RU2184058C2 (ru) 2002-06-27
FR2759348A1 (fr) 1998-08-14
CA2278668A1 (fr) 1998-08-13
JP3294858B2 (ja) 2002-06-24
US6189688B1 (en) 2001-02-20

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