EP1010635B1 - Capuchon de fermeture d'un récipient pour médicaments avec un goulot façonné fermé - Google Patents

Capuchon de fermeture d'un récipient pour médicaments avec un goulot façonné fermé Download PDF

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Publication number
EP1010635B1
EP1010635B1 EP19990124158 EP99124158A EP1010635B1 EP 1010635 B1 EP1010635 B1 EP 1010635B1 EP 19990124158 EP19990124158 EP 19990124158 EP 99124158 A EP99124158 A EP 99124158A EP 1010635 B1 EP1010635 B1 EP 1010635B1
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EP
European Patent Office
Prior art keywords
seal
cap
container
pot
container neck
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP19990124158
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German (de)
English (en)
Other versions
EP1010635B2 (fr
EP1010635A2 (fr
EP1010635A3 (fr
Inventor
Albert Louis Victor Josef Claessens
Serge Leon Guy Marie Ghislain De Schaetzen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Helvoet Pharma NV
Datwyler Pharma Packaging Belgium NV
Original Assignee
Helvoet Pharma NV
Helvoet Pharma Belgium NV
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Filing date
Publication date
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Application filed by Helvoet Pharma NV, Helvoet Pharma Belgium NV filed Critical Helvoet Pharma NV
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Publication of EP1010635A3 publication Critical patent/EP1010635A3/fr
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1406—Septums, pierceable membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A61J1/1418—Threaded type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A61J1/1431—Permanent type, e.g. welded or glued
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1475—Inlet or outlet ports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means

Definitions

  • the invention relates to a pot-shaped cap with a lid and a Mantle area for fixed arrangement on a closed container neck of a Medicament, in particular infusion container, wherein in the lid portion of the cap at least two puncture openings are provided and in the lid area one of an elastic material produced and the puncture openings covering seal which is inserted in a chamber formed integrally with the lid region, the with the inserted seal over the outside of the lid area to the outside protrudes, and the seal is disc-shaped.
  • Such known drug or infusion containers solve more and more the earlier exclusively used and made from glass infusion bottles.
  • this infusion container made of a soft plastic material one more Bottle shape, but are also increasingly produced in bag form.
  • the drug produced in such soft plastic or Infusion containers are filled drug after its filling in the container and after being hermetically sealed it is absolutely protected and it first turns again at the scheduled withdrawal of the drug from the container the problem to be able to perform this clean and sterile, because the drug or Infusion container must be opened.
  • it is common in piercing such an infusion container cannulas for example to the To ventilate the interior of the container and / or to inject additional medication.
  • the drug or infusion containers on their Container neck provided with the above-described known cap, consisting of a firmer or harder plastic material is made and the between itself and the container neck of the drug or infusion container includes a seal, through which the cannula or the hollow mandrel of an infusion set is pushed, wherein the hollow dome is held by this seal against slipping when the Infusion bottle is held over head.
  • EP 0 364 783 B1 discloses a closure cap which is closed on the closure Container neck of a medicament made of soft plastic material. or infusion container is attached.
  • This made of harder plastic material produced cap overlaps with its cylindrically shaped shell part the cylindrical outer wall of the container neck, wherein the cap with its Lidded area is arranged at a distance from the lid surface of the container neck, so that there is a cavity of certain volume between the two, which for the Arrangement of a seal is provided.
  • the lid portion of the cap has at least one puncture opening, which is closed from the outside with a film.
  • the in between the cap on the one hand and the container neck or the Cover surface of the container neck on the other hand contained existing cavity Seal is made of a soft sealant, with the seal in the Puncture hole protrudes and this sealant with the cap, so with the inner surfaces of the cap in the region of the cavity completely is welded.
  • the Make cap in its lid area so that it is a tearable Cover part is provided, wherein integrally formed on this cover part a tab is, by means of which the tear-out part are torn out of the cap can, so that an opening is formed in the lid portion of the cap. It is below this opening a perforated disc provided with the bottom of the Lid region of the cap is firmly connected by welding.
  • the Perforated disk has several holes, which have different diameters can and through which the cannulas or hollow mandrels can be passed.
  • a sealing disc is provided below this perforated disc, which on the Top of the lid surface of the container closure rests and the piercing a cannula or a hollow mandrel through the holes of the perforated disc in the container into the sealing function takes over.
  • the gasket is designed so that it fills the closure cap diameter moderately full and therefore relatively a lot of material has to be spent.
  • the Disadvantage that form during the piercing permanent cavities can, because the seal on the one hand and the lid surface of the container neck on the other hand, because of their different material properties, e.g. Elasticities, different from each other and in these resulting cavities can accumulate drug fluid if the infusion bottle over head is hung.
  • EP 0 721 897 A1 discloses a generic cap for a medicament container, in particular described an infusion container, in which the two puncture areas is covered by a one-piece seal extending over both puncture areas, which is encased at its edges.
  • this seal can with its to the top the container neck directed sealing surface not on the top of the container neck to sealing contact, since the bottom of the seal from a bridge to the top of the Container neck is spaced, this web is a part of the cap.
  • the bottom of the seal on the one hand and the top of the medicine container On the other hand, therefore, there remains a gap, which, as already explained in detail above described, may be disadvantageous.
  • the invention has on the one hand the Task asked a cap of the type described above in terms of their To improve sterile properties, ie in particular the sealing effect between the in the cap existing seal on the one hand and the top surface of the container neck on the other hand to increase and on the other hand, the further task, such a cap so form that produced for the particularly elastic and therefore expensive material Seal are made relatively small compared to the known seals can.
  • This above-described embodiment of the closure cap according to the invention forms the arrangement in each case a single seal in a single associated with this seal Chamber in the lid area a tight fit for each seal inserted therein, the ensures that the seal during the piercing process not too strong Suffers deformation, which is about when a second puncture opening on the underlying area of the same seal transmits.
  • Embodiment ensures that the respective puncture opening associated seal is not affected by the adjacent seal with respect to deformations, etc.
  • the cylinder portion in its axial inner wall on a circumferential groove, in which the circular cross-section having a disc-shaped seal with a formed on its axial outer wall peripheral projection.
  • the projection on at least one point on an interruption facilitates the For example, to be performed by an assembly machine insertion of the seals into the chamberings in that air, which is in the closed Chamber area of the cap is located, through these interruptions can escape, so not a cushion of compressed air between Seal on the one hand and the Kamm réelle on the other hand, which could cause the seal is pushed out of the chamber after insertion.
  • the seal is in its central area in Thickness formed their thickness, for example, by specifying depressions in at least one of its radial sealing surfaces.
  • the puncture opening provided on the outside of the chambering has a rupturable closure formed in one piece with the lid region of the closure cap.
  • a rupturable closure formed in one piece with the lid region of the closure cap.
  • the rupturable closure on a tear-open can also be formed in a manufacturing process, it can be grasped and pulled up with a finger, so that the underlying puncture opening, without touching it, is opened and the hollow dome of an infusion set can be inserted.
  • the tear lever is a hinge on the outside attached to the Kamm réelle, so that the tearing lever is not after tearing the Puncture is lost, but together with the cap or the entire, emptied medication container can be disposed of.
  • two puncture openings are provided in the lid region of the closure cap. These can be used independently, in particular opened, showing the advantage that their respective. Seals are completely independent of each other and thus do not interfere with each other when piercing the hollow dome.
  • the seal used in the chamberings can be made of rubber, but also on the other hand be made of a plastic, depending on the requirements of the Properties of the seal are made.
  • the invention further relates to a medicament, in particular infusion container, with a closure cap according to one of claims 1 to 11, which is made of a plastic and in which also made of plastic and attached with its jacket portion on the container neck cap with the Container neck is welded. This formation of the connection of the container neck with the cap results in an absolutely tight and thus secure connection.
  • the top of the container neck is welded to the underside of the chamber.
  • the pressure exerted by this on the cover surface of the container neck pressure this too strong bends into the interior of the container inside.
  • the top surface of the lid surface of the container neck facing sealing surface of the seal also after piercing the same rests on the top of the lid surface of the container neck.
  • the top of the container neck is also welded to the sealing surface of the seals. This additional measure ensures a particularly good seal between these individual parts of the medicament container and the closure cap.
  • the closure cap 1 shown in the figures is substantially pot-shaped formed, that is, it has a lid portion 2 and a cladding region 3, with which they, as shown in Fig. 6, the closed-trained container neck. 4 a medicament container 5, for example an infusion container.
  • the cap 1 a not described here in detail especially have trained jacket edge 6, with which they, for example, on a attached circular flange 7 of the container neck 4 of the medicament container 5, for example screwed or welded.
  • the closure cap 1 with the inside 8 of its shell 3 with the outer surface the container neck 4 is glued or welded.
  • closures 10 and 10 ' are also integrally formed, with Tear levers 11 and 11 'are provided under which are gripped with a finger can, then with appropriate force, the closures 10 and 10 'off the lid portion 2 of the cap 1 tearing out and thus the Puncture openings 9 and 9 'free.
  • the locking device consists of a part 26 which is provided on the Aufr Constant 13 and 11 ', and a second part 27, which is formed on the outside of the Kammerugen 13 or 13 ' and in the torn open position of the tearing levers 11 and 11 'for Complete locking device, such as in a hook and eye connection or, more like a lower and a upper hook.
  • the lid region 2 of the closure cap 1 is in the region of the puncture openings 9 or 9 'formed in a special form, where it has namely each puncture opening a chamber 13 or 13 ', which is opposite to the outside 14 of the Cover area 2 protrude outward to the extent that the top of the 15 Container neck 4 directed sealing surfaces 16 and 16 'of in the chamberings 13th or 13 'inserted seals 17 and 17' only slightly above the inside of the 18th of the lid portion 2 protrude.
  • This Holding devices are, as can be seen in particular from FIGS. 5 to 7, formed in the manner of tongue and groove between the chambers 13 and 13 ' and seals 17 and 17 'are formed.
  • the Seals 17 and 17 'are made Due to the soft and deformable nature of the material from which the Seals 17 and 17 'are made, they can easily in the Chambers 13 and 13 'of the cap 1, which consists of a harder Are made of plastic material, are used or pressed in, the encircling projections 22 and 22 'easily in the grooves 20 and 20' engage. This can be done by a special assembly machine.
  • the puncture areas specify for the hollow mandrel of an infusion set.
  • the container neck with the inside of the shell 3 of the also made of plastic closure cap 1 in a simple manner this welded, resulting in a very tight connection.
  • the top 15 of the container neck 4 with the Bottom of the chamber and possibly also in addition to the lower Sealing surfaces of the seals, if this example made of plastic are, welded. This measure results in a very intimate and dense Connection of the individual components, especially in the area of the puncture areas.

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Closures For Containers (AREA)

Claims (14)

  1. Capuchon en forme de pot présentant une zone de couvercle et une zone d'enveloppe (respectivement 2 et 3) destiné à être disposé de manière fixe sur un col de récipient (4) réalisé fermé d'un récipient à médicament, en particulier un récipient à perfusion (5), au moins deux orifices à transpercer (respectivement 9 et 9') étant prévus dans la zone du couvercle (2) du capuchon (1) et une garniture d'étanchéité (respectivement 17 et 17') fabriquée dans une matière élastique et recouvrant les orifices à transpercer (respectivement 9 et 9'), se trouvant dans la zone du couvercle (2), laquelle garniture d'étanchéité est placée dans une chambre (respectivement 13 et 13') réalisée d'un seul tenant avec la zone du couvercle (2) et qui, avec la garniture d'étanchéité placée à l'intérieur, dépasse vers l'extérieur du côté extérieur (14) de la zone du couvercle, et la garniture d'étanchéité (respectivement 17 et 17') est réalisée en forme de rondelle, caractérisé en ce que pour chaque orifice à transpercer est prévue une garniture d'étanchéité (respectivement 17 et 17') qui est insérée dans une chambre (respectivement 13 et 13') respective dont la forme est adaptée à la garniture d'étanchéité respective, les garnitures d'étanchéité (respectivement 17 et 17') étant réalisées chacune en forme de rondelle cylindrique circulaire et les chambres (13 respectivement 13') respectives sont réalisées en forme de cylindres creux correspondants, en ce que les chambres (13 ou 13') respectives sont réalisées ouvertes vers le côté supérieur (15) du col du récipient (4), et en ce que les garnitures d'étanchéité (17 ou 17') dépassent, à travers la zone du couvercle (2), vers le bas, de la face intérieure (18) de la zone du couvercle (2) du capuchon (1), leurs surfaces d'étanchéité (16 ou 16'), dirigées vers le côté supérieur (15) du col du récipient (4) réalisé fermé, pouvant s'appliquer de manière étanche sur le côté supérieur (15) d'un col de récipient (14).
  2. Capuchon en forme de pot selon la revendication 1, caractérisé en ce que chaque chambre (13 ou 13') présente, dans sa paroi intérieure (19 ou 19') cylindrique, une rainure (20 ou 20') périphérique dans laquelle la garniture d'étanchéité (17 ou 17') pénètre par une saillie (22 ou 22') périphérique réalisée sur sa paroi extérieure (21 ou 21') cylindrique.
  3. Capuchon en forme de pot selon la revendication 2, caractérisé en ce que la saillie (22 ou 22') présente une interruption en au moins un point.
  4. Capuchon en forme de pot selon la revendication 1, caractérisé en ce que la garniture d'étanchéité (17 ou 17') est réalisée avec une épaisseur moindre dans sa zone centrale.
  5. Capuchon en forme de pot selon la revendication 4, caractérisé en ce que la garniture d'étanchéité (17 ou 17') présente un renfoncement (24 ou 25) dans la zone centrale d'au moins l'une de ses surfaces d'étanchéité (16 ou 23) radiales.
  6. Capuchon en forme de pot selon la revendication 1, caractérisé en ce que la chambre (13 ou 13') présente, dans la zone de l'orifice à transpercer (9 ou 9'), une fermeture (10 ou 10') réalisée en une seule pièce, qui peut être arrachée.
  7. Capuchon en forme de pot selon la revendication 6, caractérisé en ce que la fermeture (10 ou 10') qui peut être arrachée comporte un levier d'arrachage (11 ou 11').
  8. Capuchon en forme de pot selon la revendication 7, caractérisé en ce que le levier d'arrachage (11 ou 11') est fixé par une charnière (12 ou 12') sur le côté extérieur de la chambre (13 ou 13').
  9. Capuchon en forme de pot selon la revendication 8, caractérisé en ce que le levier d'arrachage (11 ou 11') d'une part et le côté extérieur de la chambre (13 ou 13') d'autre part, comportent chacun des parties (26) et (27) d'un dispositif d'arrêt qui sont réalisées complémentaires l'une de l'autre et sont associées l'une à l'autre de manière à former le dispositif d'arrêt lorsque le levier d'arrachage (11 ou 11') est arraché.
  10. Capuchon en forme de pot selon l'une des revendications précédentes, caractérisé en ce que la garniture d'étanchéité (17 ou 17') est réalisée en caoutchouc.
  11. Capuchon en forme de pot selon l'une des revendications 1 à 9 précédentes, caractérisé en ce que la garniture d'étanchéité (17 et 17') est réalisée dans une matière plastique.
  12. Récipient à médicament, en particulier récipient à perfusion, comportant un capuchon en forme de pot selon l'une des revendications 1 à 9 précédentes, caractérisé en ce que le récipient (5) est fabriqué dans une matière plastique et le capuchon (1), également fabriqué en matière plastique et placé par sa zone d'enveloppe (3) sur le col de récipient (4), est soudé avec le col de récipient (4).
  13. Récipient à médicament, en particulier récipient à perfusion, selon la revendication 12, caractérisé en ce que le côté supérieur (15) du col de récipient (4) est soudé avec le côté inférieur de la chambre (13 et 13').
  14. Récipient à médicament, en particulier récipient à perfusion, selon la revendication 13, caractérisé en ce que le côté supérieur (15) du col de récipient (4) est soudé aussi avec la surface d'étanchéité, (16 ou 16') de la garniture d'étanchéité (17 ou 17').
EP19990124158 1998-12-18 1999-12-02 Capuchon de fermeture d'un récipient pour médicaments avec un goulot façonné fermé Expired - Lifetime EP1010635B2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1998158715 DE19858715B4 (de) 1998-12-18 1998-12-18 Entnahmevorrichtung zur festen Anordnung auf dem geschlossen ausgebildeten Behälterhals eines Medikamenten-, insbesondere Infusionsbehälters
DE19858715 1998-12-18

Publications (4)

Publication Number Publication Date
EP1010635A2 EP1010635A2 (fr) 2000-06-21
EP1010635A3 EP1010635A3 (fr) 2001-05-02
EP1010635B1 true EP1010635B1 (fr) 2004-03-03
EP1010635B2 EP1010635B2 (fr) 2007-10-24

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EP19990124158 Expired - Lifetime EP1010635B2 (fr) 1998-12-18 1999-12-02 Capuchon de fermeture d'un récipient pour médicaments avec un goulot façonné fermé

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EP (1) EP1010635B2 (fr)
DE (3) DE19858715B4 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004051300B3 (de) * 2004-10-20 2005-11-17 Fresenius Kabi Deutschland Gmbh Verschlusskappe für mit medizinischen Flüssigkeiten befüllte Behältnisse
US8181801B2 (en) 2006-10-23 2012-05-22 Thermo Fisher Scientific Oy Reagent closure

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DE10311154A1 (de) * 2003-03-14 2004-09-23 Helvoet Pharma Belgium N.V. Für pharmazeutische Verwendung dienende Überkappe mit Verschlussstopfen
DE102004042290A1 (de) * 2004-09-01 2006-03-02 Helvoet Pharma Belgium N.V. Medizinischer Verpackungsbehälter
DE202005015861U1 (de) * 2005-10-13 2007-02-15 Pharmaplan International Gmbh Verschlusskappe für mit medizinischen Flüssigkeiten gefüllte Behältnisse
ITBO20080475A1 (it) * 2008-07-30 2010-01-31 Brev Angela Srl Inserto perforabile per contenitore.
FI20116059A (fi) 2011-10-28 2013-04-29 Thermo Fisher Scientific Oy Reagenssipullo, järjestelmä, menetelmä ja laite suljinkorkkien ja vastaavien käsittelemiseksi
EP3137213B1 (fr) 2014-04-28 2019-09-25 Thermo Fisher Scientific Oy Bouchon de flacon de réactif, système et procédé pour manipuler des bouchons de fermeture et similaire
US11351090B2 (en) * 2015-03-27 2022-06-07 Fresenius Kabi Deutschland Gmbh Sealing cap for a container for holding a medical liquid
DE102016003253A1 (de) 2016-03-16 2017-09-21 Braunform Gmbh Modulierbare und adaptierbare Verschlusskappe für Behältnisse.
JP7016315B2 (ja) * 2016-06-02 2022-02-04 大塚テクノ株式会社 キャップ
CN110420120B (zh) * 2019-08-13 2021-12-17 山东金阳光医药包装有限公司 一种塑料药瓶

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FR1325077A (fr) * 1962-03-16 1963-04-26 Bouchon, en particulier pour flacon de perfusion sanguine
DE4425433C1 (de) * 1994-07-19 1996-02-29 Fresenius Ag Behältnis zur Aufnahme medizinischer Flüssigkeit
DE19539897A1 (de) * 1995-09-13 1997-03-20 Pohl Gmbh Kappenverschluß für einen Behälter

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DE3835720A1 (de) * 1988-10-20 1990-05-03 Wimmer Pharma Gummi Gmbh Verschluss fuer eine medikamentenflasche und verfahren zur herstellung dieses verschlusses
DE4231750C1 (de) * 1992-09-23 1994-03-10 Pohl Gmbh & Co Kg Infusionsflasche aus Kunststoff
DE4327845C2 (de) * 1993-08-19 1995-06-29 Matthias Faensen Gmbh & Co Kg Verschluß für einen Behälter
DE19500460A1 (de) * 1995-01-10 1996-07-11 Pohl Gmbh & Co Kg Anordnung an Infusionsflaschen oder dergleichen

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Publication number Priority date Publication date Assignee Title
FR1325077A (fr) * 1962-03-16 1963-04-26 Bouchon, en particulier pour flacon de perfusion sanguine
DE4425433C1 (de) * 1994-07-19 1996-02-29 Fresenius Ag Behältnis zur Aufnahme medizinischer Flüssigkeit
DE19539897A1 (de) * 1995-09-13 1997-03-20 Pohl Gmbh Kappenverschluß für einen Behälter

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004051300B3 (de) * 2004-10-20 2005-11-17 Fresenius Kabi Deutschland Gmbh Verschlusskappe für mit medizinischen Flüssigkeiten befüllte Behältnisse
AU2005297511B2 (en) * 2004-10-20 2012-02-02 Fresenius Kabi Deutschland Gmbh Closing cap for containers filled with medical liquids
US8211081B2 (en) 2004-10-20 2012-07-03 Fresenius Kabi Deutschland Gmbh Closing cap for containers filled with medical liquids
DE102004051300C5 (de) * 2004-10-20 2013-01-24 Fresenius Kabi Deutschland Gmbh Verschlusskappe für mit medizinischen Flüssigkeiten befüllte Behältnisse
US8181801B2 (en) 2006-10-23 2012-05-22 Thermo Fisher Scientific Oy Reagent closure

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Publication number Publication date
DE29824812U1 (de) 2002-09-12
EP1010635B2 (fr) 2007-10-24
EP1010635A2 (fr) 2000-06-21
DE59908724D1 (de) 2004-04-08
DE19858715A1 (de) 2000-06-29
DE19858715B4 (de) 2004-08-12
EP1010635A3 (fr) 2001-05-02

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