EP0637750A2 - Procédé d'analyse des échantillons liquides - Google Patents

Procédé d'analyse des échantillons liquides Download PDF

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Publication number
EP0637750A2
EP0637750A2 EP94111919A EP94111919A EP0637750A2 EP 0637750 A2 EP0637750 A2 EP 0637750A2 EP 94111919 A EP94111919 A EP 94111919A EP 94111919 A EP94111919 A EP 94111919A EP 0637750 A2 EP0637750 A2 EP 0637750A2
Authority
EP
European Patent Office
Prior art keywords
data
reagent
analysis
vessel
high information
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP94111919A
Other languages
German (de)
English (en)
Other versions
EP0637750A3 (fr
Inventor
Karl-Heinz Mann
Alfred Lang
Ernst Nowak
Stephan Sattler
Hans Dr. Schels
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH, Boehringer Mannheim GmbH filed Critical Roche Diagnostics GmbH
Publication of EP0637750A2 publication Critical patent/EP0637750A2/fr
Publication of EP0637750A3 publication Critical patent/EP0637750A3/fr
Withdrawn legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00613—Quality control
    • G01N35/00663—Quality control of consumables
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/54—Labware with identification means
    • B01L3/545—Labware with identification means for laboratory containers
    • B01L3/5453—Labware with identification means for laboratory containers for test tubes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002—Reagent dispensers
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B19/00—Programme-control systems
    • G05B19/02—Programme-control systems electric
    • G05B19/04—Programme control other than numerical control, i.e. in sequence controllers or logic controllers
    • G05B19/12—Programme control other than numerical control, i.e. in sequence controllers or logic controllers using record carriers
    • G05B19/128—Programme control other than numerical control, i.e. in sequence controllers or logic controllers using record carriers the workpiece itself serves as a record carrier, e.g. by its form, by marks or codes on it
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K19/00—Record carriers for use with machines and with at least a part designed to carry digital markings
    • G06K19/06—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
    • G06K19/06009—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code with optically detectable marking
    • G06K19/06037—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code with optically detectable marking multi-dimensional coding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00613—Quality control
    • G01N35/00663—Quality control of consumables
    • G01N2035/00673—Quality control of consumables of reagents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00742—Type of codes
    • G01N2035/00752—Type of codes bar codes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00742—Type of codes
    • G01N2035/00782—Type of codes reprogrammmable code
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B2219/00—Program-control systems
    • G05B2219/20—Pc systems
    • G05B2219/23—Pc programming
    • G05B2219/23342—Pluggable rom, smart card
    • G—PHYSICS
    • G05—CONTROLLING; REGULATING
    • G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
    • G05B2219/00—Program-control systems
    • G05B2219/20—Pc systems
    • G05B2219/23—Pc programming
    • G05B2219/23363—Barcode

Definitions

  • the invention relates to a method for analyzing sample liquids, in which data carriers of high information density are mounted on vessels with reagent solutions, which are used to carry out and control the analysis. Furthermore, the invention relates to a method for producing reagent vessels provided with data carriers and a system for analyzing sample liquids in which reagent vessels provided with code carriers are used.
  • Patent application WO 89/08264 describes a method for the automatic, fully selective analysis of blood or its components. The method is based on the fact that data of the patient and the sample are attached to a sample vessel in the form of a battery-free, electronic code carrier. This combination of data carrier and sample container enables the sample to be assigned to a patient during the entire analysis process.
  • the patent US 4,975,647 discloses the use of test tubes which are connected to an identification device.
  • the identification device contains a PROM (programmable read-only memory) in which data relating to the reagent liquids are stored.
  • the identification devices mentioned are connected to an analysis device via electromechanical contacts.
  • the data stored in the PROM can serve to control the analysis, but the establishment of an electromechanical connection between the identification device and the analysis device is inconvenient for the user and moreover prone to errors.
  • the relatively complex and expensive structure of the identification device prevents single use.
  • the invention was therefore based on the object of providing a method and a system which contains test tubes which have contactless data carriers, which enable control of the analysis process and are so simple and inexpensive in their construction that they if necessary, can be discarded after the analysis. It was also an object of the invention to propose data carriers whose amount of data is so large that control programs for automated analyzers can also be stored.
  • the invention also relates to a method for producing a reagent vessel provided with a data carrier, in which data with a high information density are attached directly after the filling.
  • a system according to the invention contains an analysis device. Numerous analysis devices have been described in the prior art (e.g. DE-OS 3839080, EP-0078948, EP-0216026).
  • An analysis device in the sense of the invention has an arrangement of samples that are to be analyzed, an arrangement for receiving reagent vessels and a device for pipetting liquids. Analysis devices also have a measuring device, which in many cases is provided by a photometer, but also by other devices known in the art, such as.
  • B. conductivity measuring cells, potentiometric measuring cells, etc. can be represented. The signals of the measuring cell are evaluated with a computing unit and shown and / or printed out on a display.
  • a system according to the invention further includes one or more data readers.
  • larger analysis devices often have bar code, magnetic stripe or chip card readers.
  • barcode readers that read data attached to samples and / or reagent containers have proven successful.
  • the one-dimensional bar codes used in the prior art for this purpose have a storage capacity of a few bytes. For this reason, relatively little data, such as B. expiry date, batch number and key figures for the contents of the container and bottle size can be saved.
  • a database that is already present in the analysis device must be accessed to assign these key figures.
  • the storage capacity is increased by a preferred use of two-dimensional bar codes or particularly preferably by the use of contactless chip cards.
  • bar codes or contactless chip cards is of particular advantage, since reading can take place without the need to close electrical contacts or touching. There are therefore both operating errors, e.g. B. reverse polarity, as well as mechanical problems such. B. unstable contacts or wear and tear on magnetic card readers.
  • the aforementioned data carriers also have the advantage that they can be produced inexpensively and generate little waste, so that single use is possible. Many test tubes are used only once because cleaning them would be too expensive. In these cases too, a fixed connection of two-dimensional bar codes or contactless chip cards to the reagent vessel is possible due to the low cost.
  • An increased storage capacity enables process sequences to be stored on test tubes without the need for further access to a database in the analysis system. It is particularly advantageous if the greatest possible number of different analyzes can be carried out with one analysis device. This presupposes that the analysis device is able to carry out different process sequences depending on the analysis. For example, procedures such as diluting a reagent, mixing reagents and observing incubation times may become necessary.
  • the process sequences stored on the data carriers can relate to units of higher-level processes, which in turn consist of a large number of individual processes.
  • a higher-level process "pipetting” could include process steps that move the pipette over a test tube, immerse it in the liquid, draw liquid of a certain amount into it, etc.
  • Data carriers with a high density of information can store the process sequences mentioned.
  • a system according to the invention can therefore read in data which are stored on a reagent vessel and which contain instructions for process sequences.
  • the executable processes can thus be optimally matched to the respective reagent.
  • the wavelength of the radiation at which the analysis is to be carried out for example, or the sensitivity range with which the measurement is to be carried out can be stored on the data carrier.
  • the analysis device can be calibrated, for example, by reading information from the data carrier relating to a relationship between the measurement signal and the concentration of analytes.
  • test tubes with barcodes are assigned to test tubes with data carriers with high information density. Information from data carriers with a high density of information can thus also be used for the test tubes with bar codes.
  • Two-dimensional bar codes are preferably used as the data carrier of high information density. These are already known in the prior art and are manufactured by Symbol Technologies under the process name PDF 417. The information density that can be achieved is approximately 480 ASCII characters per inch2.
  • Contactless chip cards are particularly preferred data carriers in the context of the invention. These contain a transmission / reception coil which is controlled by a spatially separate electromagnetic transmitter. In this process, the electrical energy for operating the chip is transmitted as well as impulses that trigger computing and storage processes in the chip. Contactless chip cards are on the market e.g. B. from Philips under the designation V7930.
  • the characteristic values of the concentration can also be saved subsequently on the reagent container.
  • the label can only be applied immediately before delivery, i.e. H. Extensions to the data content, e.g. B. Extension of the expiry date is possible until then.
  • the usage history can be determined for reagent containers that are returned to the manufacturer for disposal.
  • the data carriers of returned reagent containers can be reused, however, because of the simple and inexpensive construction of contactless chips, one-time use is also possible.
  • the Evidence of the reagent quality can be checked at any time, all effects that the reagent has experienced during production and use.
  • the system for analyzing liquids must have a writing device that can control the contactless chip.
  • Write and read devices for contactless chips are also available from Philips.
  • the described data carriers with a high density of information can be glued to the respective reagent tubes, directly printed on in the case of bar codes, welded on or clamped on, or in the case of contactless chips they can also be located inside the reagent tube.
  • the following procedure relates to the immunological test "TSH".
  • TSH immunological test
  • Figure 1 shows a reagent vessel (1) made of polyethylene, on which a two-dimensional bar code (2) is glued on one side.
  • the bar code can be read into an analysis device when the reagent vessel (1) is set.
  • the movement of the reagent vessel when inserted into an intended position can be used to enable the reading process.
  • reading devices are also known which enable a reading process without relative movement of the reading device and bar code.
  • FIG. 2 shows a reagent vessel (5), in which a contactless chip card, including a transmitting / receiving coil (6) and a chip (7), is glued to one of the end faces of the reagent vessel.
  • FIG. 3 shows a reagent vessel (10), in the interior of which there is an encapsulated contactless chip card (11).
  • the encapsulation of the chip card which consists of glass, is inert to common reagent solutions in clinical analysis.
  • Encapsulated contactless chip cards can be introduced into the reagent vessel through an opening (12) during the manufacturing process or when filling the reagent vessel (10). This has the advantage that there is no need to attach the chip card to the reagent vessel. In technology, transmitters are available that have a sufficient transmission strength with which the chip card can also be controlled inside the reagent vessel.
  • FIG. 4 schematically shows the structure of an analysis system (20) using reagent vessels which are provided with data carriers of high information density.
  • Reagent tubes (21), on which contactless chip cards are applied, are located on a rotatable plate (22).
  • a read / write device (R / W) is located opposite the outer edge of the rotatable plate (22).
  • the read / write device (R / W) controls the contactless chip card of the reagent vessel (21a) opposite it.
  • a computing device (CPU) can control the analysis from the data transmitted to it by the read / write device (R / W) and data entered by a user via a keyboard (IN).
  • a reagent vessel (21b) is brought into the removal position in order to carry out a specific analysis.
  • the pipetting arm (23) pipettes reagent liquid from the reagent vessel (21b) and puts it into a reaction vessel (24).
  • the pipetting arm (23) then pipettes sample liquid from a sample vessel (25) and puts it into the reaction vessel (24).
  • the computing device (CPU) starts a light source (S) which shines through the reaction vessel (24).
  • the detector (D) measures the radiation passing through the reaction vessel (24) and forwards the measurement signal to the computing device (CPU).
  • the computing device determines the analysis result and displays it on a display (OUT).

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  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Quality & Reliability (AREA)
  • Automation & Control Theory (AREA)
  • Theoretical Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
EP94111919A 1993-08-05 1994-07-30 Procédé d'analyse des échantillons liquides. Withdrawn EP0637750A3 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19934326342 DE4326342A1 (de) 1993-08-05 1993-08-05 Verfahren zur Analyse von Probenflüssigkeiten
DE4326342 1993-08-05

Publications (2)

Publication Number Publication Date
EP0637750A2 true EP0637750A2 (fr) 1995-02-08
EP0637750A3 EP0637750A3 (fr) 1997-02-19

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Family Applications (1)

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EP94111919A Withdrawn EP0637750A3 (fr) 1993-08-05 1994-07-30 Procédé d'analyse des échantillons liquides.

Country Status (3)

Country Link
EP (1) EP0637750A3 (fr)
JP (1) JPH07151766A (fr)
DE (1) DE4326342A1 (fr)

Cited By (27)

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WO1996036436A1 (fr) * 1995-04-25 1996-11-21 Irori Matrices programmables a distance et dotees de memoires, et leur utilisation
WO1997012680A2 (fr) * 1995-10-03 1997-04-10 Irori Matrices a memoires, capteurs a memoires et utilisations correspondantes
NL1005914C2 (nl) * 1997-04-28 1998-10-29 Sgt Exploitatie Bv Inrichting voor het opslaan en/of behandelen van chemicaliën.
WO1999010763A1 (fr) * 1997-08-21 1999-03-04 Carl Zeiss Jena Gmbh Support d'echantillons pouvant etre traite par informatique et procede d'analyse des echantillons
US5925562A (en) * 1995-04-25 1999-07-20 Irori Remotely programmable matrices with memories
US6025129A (en) * 1995-04-25 2000-02-15 Irori Remotely programmable matrices with memories and uses thereof
WO2000033959A1 (fr) * 1998-12-09 2000-06-15 Central Labo Europe (S.A.R.L.) Systeme d'analyse biologique comprenant un moyen de controle de l'appariement entre un equipement d'analyse biologique et un recipient complementaire
FR2806487A1 (fr) * 2000-03-15 2001-09-21 Serpe Iesm Soc D Etudes Et De Procede d'autorisation de fonctionnement d'un systeme electrique et dispositif correspondant
US6319668B1 (en) 1995-04-25 2001-11-20 Discovery Partners International Method for tagging and screening molecules
US6340588B1 (en) 1995-04-25 2002-01-22 Discovery Partners International, Inc. Matrices with memories
WO2002009020A2 (fr) * 2000-07-21 2002-01-31 Patram (Patent And Trademark Administration) Limited Procede de manutention d'un objet
EP1190771A1 (fr) * 2000-08-30 2002-03-27 Wardlaw Partners LP Procédé de contrôle de la qualité et appareil d'analyse automatique de matériau biologique
EP1419821A1 (fr) * 2002-11-14 2004-05-19 F. Hoffmann-La Roche Ag Méthode, dispositifs et enceinte de réaction pour le traitment d'échantillons biologiques
EP1508029A1 (fr) * 2002-05-28 2005-02-23 Autogenomics, Inc. Ensemble de reactifs multiples
EP1624303A2 (fr) * 2004-08-04 2006-02-08 Imi Vision Limited Diagnostiques in-vitro
USRE39545E1 (en) 1995-02-02 2007-04-03 Nexus Biosystems, Inc. Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
EP1832878A1 (fr) * 2006-03-07 2007-09-12 Hamilton Bonaduz AG Récipient avec un transpondeur assuré contre les faux
EP2282215A1 (fr) * 2005-02-09 2011-02-09 Hitachi, Ltd. Analiseur automatique
AU2005259981B2 (en) * 2004-06-29 2012-01-12 Dako Denmark A/S Method of pre-treatment and staining of and support device for a biological sample
US8900856B2 (en) 2004-04-08 2014-12-02 Biomatrica, Inc. Integration of sample storage and sample management for life science
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US9725703B2 (en) 2012-12-20 2017-08-08 Biomatrica, Inc. Formulations and methods for stabilizing PCR reagents
EP2265733A4 (fr) * 2008-03-04 2017-12-13 3M Innovative Properties Company Traitement de milieux de croissance biologiques basé sur des caractéristiques de fabrication mesurées
US9999217B2 (en) 2010-07-26 2018-06-19 Biomatrica, Inc. Compositions for stabilizing DNA, RNA, and proteins in blood and other biological samples during shipping and storage at ambient temperatures
US10064404B2 (en) 2014-06-10 2018-09-04 Biomatrica, Inc. Stabilization of thrombocytes at ambient temperatures
US10568317B2 (en) 2015-12-08 2020-02-25 Biomatrica, Inc. Reduction of erythrocyte sedimentation rate
CN117566823A (zh) * 2023-12-12 2024-02-20 江苏裕隆环保有限公司 一种分散式污水处理用ega智能槽远程智能控制系统

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US6416714B1 (en) 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
US5751629A (en) 1995-04-25 1998-05-12 Irori Remotely programmable matrices with memories
US6331273B1 (en) 1995-04-25 2001-12-18 Discovery Partners International Remotely programmable matrices with memories
US6017496A (en) 1995-06-07 2000-01-25 Irori Matrices with memories and uses thereof
US5741462A (en) 1995-04-25 1998-04-21 Irori Remotely programmable matrices with memories
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
JP4795580B2 (ja) * 2001-08-30 2011-10-19 シスメックス株式会社 試薬管理方法および分析装置
JP4130905B2 (ja) * 2003-06-23 2008-08-13 株式会社日立ハイテクノロジーズ 自動分析装置
DE102006019422A1 (de) * 2006-04-26 2007-10-31 Siemens Ag Cartridge zur Durchführung einer Analyse, Analysegerät und Verfahren zur Durchführung einer Analyse mittels einer Cartridge
US7688207B2 (en) * 2006-07-28 2010-03-30 Abbott Laboratories Inc. System for tracking vessels in automated laboratory analyzers by radio frequency identification
JP2008203007A (ja) * 2007-02-19 2008-09-04 Hitachi High-Technologies Corp 自動分析装置
JP2008224382A (ja) * 2007-03-12 2008-09-25 Olympus Corp 試薬容器
JP2008224384A (ja) * 2007-03-12 2008-09-25 Olympus Corp 分析装置および分析方法
JP5277245B2 (ja) * 2008-05-22 2013-08-28 株式会社日立ハイテクノロジーズ 自動分析装置
DE102008041066A1 (de) * 2008-08-07 2010-02-11 Robert Bosch Gmbh Verfahren zur Steuerung einer Hochdrucksatzanlage
JP5430452B2 (ja) * 2010-03-11 2014-02-26 シスメックス株式会社 試料分析装置および試薬管理方法
JP5264851B2 (ja) * 2010-09-29 2013-08-14 シスメックス株式会社 自動分析装置及び試薬管理方法
JP5535047B2 (ja) * 2010-11-18 2014-07-02 株式会社日立ハイテクノロジーズ 自動分析装置
JP5795999B2 (ja) * 2012-09-18 2015-10-14 株式会社日立ハイテクノロジーズ 自動分析装置
JP6250967B2 (ja) * 2013-07-23 2017-12-20 東芝メディカルシステムズ株式会社 自動分析装置
EP3832312B1 (fr) * 2018-07-27 2023-12-13 Hitachi High-Tech Corporation Dispositif d'analyse automatique et système d'analyse automatique

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DE4326342A1 (de) 1995-02-09
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