EP0594820A1 - Recipient a vis servant de distributeur de liniments pharmaceutiques et/ou cosmetiques ou analogues, produits a l'aide d'un melangeur-agitateur - Google Patents

Recipient a vis servant de distributeur de liniments pharmaceutiques et/ou cosmetiques ou analogues, produits a l'aide d'un melangeur-agitateur

Info

Publication number
EP0594820A1
EP0594820A1 EP93909978A EP93909978A EP0594820A1 EP 0594820 A1 EP0594820 A1 EP 0594820A1 EP 93909978 A EP93909978 A EP 93909978A EP 93909978 A EP93909978 A EP 93909978A EP 0594820 A1 EP0594820 A1 EP 0594820A1
Authority
EP
European Patent Office
Prior art keywords
screw
jar
central opening
stirring tool
stirring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP93909978A
Other languages
German (de)
English (en)
Other versions
EP0594820B1 (fr
Inventor
Albrecht Konietzko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6459068&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP0594820(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of EP0594820A1 publication Critical patent/EP0594820A1/fr
Application granted granted Critical
Publication of EP0594820B1 publication Critical patent/EP0594820B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/40—Mixers with shaking, oscillating, or vibrating mechanisms with an axially oscillating rotary stirrer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/502—Vehicle-mounted mixing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32—Driving arrangements
    • B01F35/32005—Type of drive
    • B01F35/3202—Hand driven
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S215/00—Bottles and jars
    • Y10S215/08—Mixing

Definitions

  • Screw jar as a dispensing vessel for pharmaceutical and / or cosmetic ointments or the like that can be produced with a stirrer.
  • the invention relates to a screw jar as a dispensing vessel with a stirrer that can be produced pharmaceutical and / or cosmetic ointments, pastes, creams, gels, emulsions or the like, with or without the addition of solid constituents.
  • formula mixtures of fats and gels with other liquids, with or without the addition of solid components are generally triturated and mixed by hand with a so-called ointment mortar using a pestle.
  • the ointment mixing or mixing machines on the market more or less imitate this process.
  • the ointment In order to achieve homogeneous mixtures, the ointment must be slowly built up in several steps. The individual components must be weighed separately and gradually added to each other. If solid substances are not sufficiently dispersed at the start of production, subsequent fine processing with an ointment mill may also be necessary in order to grind remaining powder lumps or crystalline constituents.
  • the production takes place in wide open vessels with unhindered air access.
  • the number of airborne nuclei which are simultaneously introduced into the mixing vessel is irresponsibly large. All used equipment has to be cleaned extensively in order to make it ready for use again. In any case, the mix must be poured into a dispensing vessel.
  • the object of the invention is to remedy this and above all in the area of small dispensing quantities, for example. in the scope of recipe mixes to enable a good mixing of ointments, pastes, creams, gels and emulsions or the like and to avoid transferring or filling the recipe mixes from large open mixing vessels into small dispensing vessels.
  • a screw jar designed as a dispensing vessel can also be used as a mixing vessel in the production of recipe mixtures, the screw lid of which can be screwed onto an external thread of the jar body has a closable central opening for carrying out the drive shaft for a stirring tool of the agitator.
  • the mixing of the recipe components in the closed system is carried out with the absence of air. Transferring the ointments, pastes, creams, gels, emulsions or the like from a large mixing vessel into small dispensing vessels is not necessary.
  • the mixing vessel is both a dispensing vessel and a storage vessel.
  • a plug that is attached to it is provided.
  • the jar body is a circular cylinder, the end of which lies opposite the external thread and has a bottom opening and an inner ring, and in which a bottom is slidably arranged. It is thus possible to gradually push the contents of the screw jar out of the screw jar through the central opening of the screw lid or by an applicator. Within the scope of the invention it is possible to attach different applicators in the central opening of the screw cap using a clip connection.
  • the inner shell and the outer shell of the jar body taper from the outer thread to the solid bottom in the manner of a truncated cone.
  • the inner surface of the solid base is adapted to the shape of the stirring tool.
  • a paddle stirrer that can be inserted into the screw jar and is executable from the end of the drive shaft of a variable-speed electric motor and is provided with areas is used for the stirring tool which bear or can be placed under pressure on the inner surfaces of the screw jar.
  • the stirring tool has half-moon-shaped stirring blades with friction surfaces on the wing parts lagging during stirring, which rest elastically on the inner casing of the jar body.
  • the wing ends are drawn so far into the mixing area that when the mixing tool rotates, the inertia of the material to be mixed increases the pressure of the friction surfaces on the inner jacket of the screw jar.
  • the distance between opposing friction surfaces in the extended state is larger than the diameter of the screw jar.
  • FIG. 1 shows a cross section through a first exemplary embodiment of the invention along the line I-I in FIG. 4,
  • FIG. 3 shows a cross section through a jar body according to a second exemplary embodiment of the invention
  • FIG. 4 shows a cross section along the line IV-IV in FIG. 1 with a plan view of a stirring tool
  • FIG. 5 shows two cross sections along the line V-V in FIG. 4,
  • Fig. 6 cross sections through different applicators
  • Fig. 7 schematically shows an agitator.
  • Fig. 1 shows in cross section a screw jar 1 with a jar body 2, which is designed as a circular cylinder. It has an inner jacket 3 with a diameter 4. The upper area of the outer casing 5 of the jar body 2 is provided with an external thread 8.
  • the displaceable base 9 is slightly curved and has an outer edge 12 which merges into a sliding ring 13.
  • the floor 9 can be done without difficulty be pushed up through the bottom opening 6. Its outer edge 12 seals against the inner jacket 3 of the jar body 2.
  • a screw cap 26 is screwed onto the external thread 8 of the jar body 2, the edge 27 of which is provided with an internal thread 28.
  • the screw cap 26 is provided with a central opening 30 which has an inner diameter 31.
  • the central opening can be closed by a plug 32 which has a central longitudinal opening 33, through which elasticity is ensured.
  • It is further provided with a grip tab 34 and fastened to the screw cover 26 by means of a connecting strip 35.
  • Two opposite holes 23 in the lower region of the crucible body 2 are provided for locking or fastening the crucible
  • FIG 2 shows the cross section through the screw cap 26, the central opening 30 sealing off the closure plug 32.
  • FIG 3 shows a second exemplary embodiment of a crucible body 15.
  • the inner jacket 16 and the outer jacket 18 are frustoconical for manufacturing reasons.
  • the taper of the jar body 15 towards the solid bottom 19 is indicated by the angle 22.
  • the average diameter of the inner jacket 16 is denoted by 17.
  • the solid bottom has a curved inner surface 20.
  • the shape of the bottom is adapted to the lower surface area of the stirring tool.
  • the external thread 21 in the upper area of the outer casing 18 corresponds to the internal thread 28 in the edge 27 of the screw cap 26.
  • Two opposite holes 24 in the lower area of the jar body 15 are provided for locking or fastening the jar body on a frame 50.
  • Fig. 4 shows the section along the line IV-IV in Fig. 1 with a plan view of the stirring tool.
  • the areas 37 in the wall of the crucible body are cut out for better explanation. This is indicated by cross-hatching. These cut-out areas 37 are also shown in FIG. 4 in order to demonstrate that the trailing wing parts 59 of the blade stirrer -56 in the extended state have a distance 60 between the friction surfaces 58 which is greater than the inner diameter 4 or the mean diameter 17 of the jar body 2 or 15. As said, the cut-out areas 37 are shown only for demonstration purposes.
  • the blade stirrer 56 has half-moon-shaped stirring blades 57 which end in blade parts 59 lagging when rotating.
  • the wing parts 59 are retracted so far into the interior of the jar that they press the friction surfaces 58 against the inner walls 3, 16 of the screw jars 1, 14 during rotation due to the inertia of the mixture.
  • Fig. 5 shows a cross section along the line VV in Fig. 4.
  • the cross section is designed in the manner of propeller profiles 61, whereby the material to be mixed when mixed on the inner surface 11 of the ver ⁇ sliding floor 9 or the inner surface 20 of the solid floor 19 is pressed.
  • the paddle 56 is shown in cross section along the line II in Fig. 4. It can be clearly seen how the friction surfaces 58 lie against the inner casing 3 of the crucible body 2.
  • the paddle stirrer 56 sits at the end of a drive shaft 54, which is guided through the central opening 30 of the screw cover 26.
  • the lower regions 64 of the paddle stirrer 56 are adapted to the shape of the inner surface 11 or 20.
  • the upper regions 63 of the paddle stirrer 56 are adapted to the inner surface 29 of the screw cap 26.
  • FIG. 6 shows applicators which have been developed in accordance with the DAB requirement for the use of ointments for the screw jar according to the invention.
  • 6a shows the cross section of suitable applicators (hub and ear 38, rectum 39, 40 and vagina 41).
  • 6e shows the connection of an applicator 42 to the screw cover 26. The connection is made by means of a clip connection 44. Part of this clip connection is the central opening 30 in the screw cover 26.
  • Each applicator 38 to 42 has one lower area 45, whose diameter 46 corresponds to the diameter 31 of the central opening 30 in the screw cap 26.
  • Each applicator 38 to 42 ends with an end ring 47, above which a clip bead 48 is arranged. The distance between the end ring 47 and the clip bead 48 corresponds to the thickness of the screw cap 26.
  • FIG. 7 schematically shows an agitator 49 through which the paddle stirrer 56 can be operated.
  • a stand 52 on which a speed-controllable electric motor 53 is attached, stands on a base plate 51. This can be moved up and down by means of a handle 55 in a manner known per se, as indicated by the double arrow next to the handle 53.
  • the described paddle stirrer 56 is connected to the end of the drive shaft 54.
  • the stirring process can take place while the operator holds the screw jar 1, 14 in his hand and moves it slowly up and down relative to the paddle stirrer (not shown).
  • the screw jars can also be fastened on a frame 50 and the electric motor 53 can be guided up and down by means of the handle 55 or automatically.
  • the screw cap 26 is unscrewed from the screw jar 1, 14. Then either the drive shaft 54 can be loosened from the chuck of the electric motor 53 and the screw cap can be removed from the drive shaft 54. However, it is also possible to detach the blade stirrer 56 from the end of the drive shaft 54 in order to pull the cover 26 off the drive shaft 54.
  • the central opening 30 of the screw cover is either closed by the sealing plug 32, or one of the applicators shown in FIG. 6 is already inserted into the central opening 30 and closed with a sealing cap 43.
  • the applicators snap so tightly into the screw cap that they do not slip when applying ointments but are easy to replace if necessary.
  • the screw jars can be made from any material known per se.
  • the paddles can be made of spring steel or nylon. Both materials allow elastic deformation.
  • the lifting movement for the paddle stirrer 56 can stop from the stop on the inner surface 29 of the screw cap 26 to the stop on the inner surface 11 or 20 of the bottom of the screw jar be performed. Without changing anything at the core of the invention, this relative movement between the screw jar 1, 14 and the paddle stirrer 56 can also be carried out by hand when the electric motor 53 is stationary.
  • screw jars 1, 14 with volumes of 10, 20, 30, 50, 75, 100, 150, 200, 250, 300 or 500 ml can be used.
  • the invention permits the use of differently shaped stirring tools in the stirring or mixing device, depending on the substances to be mixed (e.g. powder or ointment mixtures free of solid particles).
  • the invention allows that when preparing an ointment, for example, usually all of the components are incorporated into the jar at the same time. can be weighed. In general, depending on the set speed of the electric motor 53, extremely homogeneous mixing results are achieved in less than one minute.
  • the air can be displaced by filling the bottom of the recipe by pushing up the bottom to such an extent that microbial contamination as well as undesirable air inclusions and air oxidation are largely excluded.
  • the situation is approximately the same if the size of the jar with a solid base is adapted to the amount of the mix.
  • both jars comply with AMP guidelines.
  • the paddle stirrer is removed.
  • the mixing vessel is closed by the screw cap 26. If necessary, an applicator can be used. Otherwise, the closure plug 32 is pressed into the central opening 30, after which the formulation mixture is ready for dispensing.
  • the stirring tool 56 is the only implement that has to be cleaned.
  • the consumer can remove the screw cap and remove the mix or 2.
  • the consumer opens the stopper on the screw cap and pushes the mix through the central opening in the screw cap or through an applicator with slight pressure on the bottom piston.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • Cosmetics (AREA)
  • Closures For Containers (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'invention concerne un récipient à vis (1) servant de distributeur de liniments, des pâtes, des crèmes, des gels, des émulsions pharmaceutiques et/ou cosmétiques ou analogues, produits à l'aide d'un mélangeur-agitateur, avec ou sans adjonction de composants solides. Le distributeur peut également faire office de mélangeur lors de la fabrication de mélanges prescrits sur ordonnance. Le bouchon vissable (26) sur un filetage extérieur (8) du corps du récipient comporte un orifice central (30) obturable par lequel il est possible d'introduire l'arbre d'entraînement (54) d'un outil de mélange d'un mélangeur-agitateur (56).
EP93909978A 1992-05-16 1993-05-13 Systeme pour la production de pommades pharmaceutiques et/ou cosmetiques ou analogues directement dans le distributeur Expired - Lifetime EP0594820B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4216252A DE4216252C2 (de) 1992-05-16 1992-05-16 Anordnung mit einem Rührwerk zur Mischung von pharmazeutischen und/oder kosmetischen Salben, Pasten, Cremes, Geleen oder Emulsionen
DE4216252 1992-05-16
PCT/EP1993/001194 WO1993023156A1 (fr) 1992-05-16 1993-05-13 Recipient a vis servant de distributeur de liniments pharmaceutiques et/ou cosmetiques ou analogues, produits a l'aide d'un melangeur-agitateur

Publications (2)

Publication Number Publication Date
EP0594820A1 true EP0594820A1 (fr) 1994-05-04
EP0594820B1 EP0594820B1 (fr) 2000-01-19

Family

ID=6459068

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93909978A Expired - Lifetime EP0594820B1 (fr) 1992-05-16 1993-05-13 Systeme pour la production de pommades pharmaceutiques et/ou cosmetiques ou analogues directement dans le distributeur

Country Status (9)

Country Link
US (1) US5397178A (fr)
EP (1) EP0594820B1 (fr)
JP (1) JP3405542B2 (fr)
AT (1) ATE188887T1 (fr)
DE (2) DE4216252C2 (fr)
ES (1) ES2145048T3 (fr)
GR (1) GR3033283T3 (fr)
PT (1) PT594820E (fr)
WO (1) WO1993023156A1 (fr)

Cited By (1)

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Publication number Priority date Publication date Assignee Title
US10493413B2 (en) 2014-10-20 2019-12-03 Samix Gmbh Stirring tool and stirrer comprising a tool of said type

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US10493413B2 (en) 2014-10-20 2019-12-03 Samix Gmbh Stirring tool and stirrer comprising a tool of said type

Also Published As

Publication number Publication date
PT594820E (pt) 2000-07-31
US5397178A (en) 1995-03-14
JPH06509263A (ja) 1994-10-20
DE4216252A1 (de) 1993-11-18
ATE188887T1 (de) 2000-02-15
DE4216252C2 (de) 1994-05-26
WO1993023156A1 (fr) 1993-11-25
EP0594820B1 (fr) 2000-01-19
DE9321387U1 (de) 1997-12-11
GR3033283T3 (en) 2000-09-29
JP3405542B2 (ja) 2003-05-12
ES2145048T3 (es) 2000-07-01

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