EP0594820B1 - Systeme pour la production de pommades pharmaceutiques et/ou cosmetiques ou analogues directement dans le distributeur - Google Patents

Systeme pour la production de pommades pharmaceutiques et/ou cosmetiques ou analogues directement dans le distributeur Download PDF

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Publication number
EP0594820B1
EP0594820B1 EP93909978A EP93909978A EP0594820B1 EP 0594820 B1 EP0594820 B1 EP 0594820B1 EP 93909978 A EP93909978 A EP 93909978A EP 93909978 A EP93909978 A EP 93909978A EP 0594820 B1 EP0594820 B1 EP 0594820B1
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EP
European Patent Office
Prior art keywords
jug
screwed
lid
frictional
vane
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EP93909978A
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German (de)
English (en)
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EP0594820A1 (fr
Inventor
Albrecht Konietzko
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Individual
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/40—Mixers with shaking, oscillating, or vibrating mechanisms with an axially oscillating rotary stirrer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/501—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use
    • B01F33/5011—Movable mixing devices, i.e. readily shifted or displaced from one place to another, e.g. portable during use portable during use, e.g. hand-held
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/50—Movable or transportable mixing devices or plants
    • B01F33/502—Vehicle-mounted mixing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32—Driving arrangements
    • B01F35/32005—Type of drive
    • B01F35/3202—Hand driven
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S215/00—Bottles and jars
    • Y10S215/08—Mixing

Definitions

  • the invention relates to an arrangement for the production of pharmaceutical and / or cosmetic ointments, creams, gels or emulsions with or without the addition of solid components in one with a lid closable mixing vessel with an electric motor via a drive shaft that can be driven through a central opening in the cover Mixing tool with elastic blades, the outer areas Have end faces that rotate on the inner surface of the mixing vessel issue.
  • recipe mixes of fats and gels with others Liquids, with or without the addition of solid components, in general triturated by hand in a so-called ointment mortar using a pestle and mixed.
  • Ointment mortars are wide-open vessels with unhindered air access.
  • the Number of airborne germs that are introduced into the mixing vessel during mixing is irresponsible. All equipment used must are laboriously cleaned to make them ready for use again. In in any case, the mix must be transferred to a dispenser.
  • the ointment In order to achieve homogeneous mixtures, the ointment has to go in several steps build up slowly. The individual components must be weighed separately and gradually add to each other. Solid substances become too Beginning of the production process is not sufficiently dispersed Finishing with an ointment mill will also be required to to grind remaining powder lumps or crystalline components.
  • a receptacle for it is pressure-tight using a cover with tools on the side and also a passage opening for a central stirring shaft can be closed, to the inside of the receptacle releasably a stirring tool with edge areas, from the lower interior wall areas of the receptacle Can scrape off the mix, but also kneading tools - without contacting the inner wall - Can be connected to process mix with higher viscosity to be able to.
  • the laboratory device according to DE 36 38 656 A1 is for pilot experiments before large-scale ointment production designed and correspondingly expensive designed and manufactured for use in pharmacy Recipe albums totally oversized and therefore unsuitable. It can Do not meet the requirements for time-saving formulation technology. In addition comes that the mix from the receptacle into separate ointment dispensing containers has to be decanted, whereby an air germ contamination cannot be excluded.
  • One of Substances in the cement mixture is a liquid that is present before mixing a temperature of preferably 2 ° to 6 ° C is cooled.
  • the different Additives are then absolute in a vacuum between 0.05 and 0.5 bar Pressure and mixed at temperatures in the range of 0 ° to 21 ° C, to minimize the supply of air to the mixture.
  • the bone cement is prepared in a quite long cylinder by means of a stirring tool rotating in it.
  • the mixing tool consists of numerous mixing arms one above the other, which protrude at right angles from the agitator shaft. Your ends do not reach the inner wall of the cylinder.
  • the top and lower stirring arms also have no contact with the inner surfaces of the cover or the bottom, so that fabric parts unmixed on the inside walls of the container can stick.
  • the preparation of the bone cement in the operating room takes place where there is also a vacuum pump attached to the cylinder connected with a screw cap during the mixing process is closed.
  • a vacuum pump attached to the cylinder connected with a screw cap during the mixing process is closed.
  • a connection for the vacuum pump In addition to a central feed-through opening for the drive shaft of the stirring tool also a connection for the vacuum pump.
  • the lower end of the cylinder equipped with a piston-like base sits during the mixing process in a holding device, which in turn is connected to the vacuum pump.
  • the screw cap After the mixing process has been completed, the screw cap must be replaced by another Lid can be replaced with an outlet part. This creates a "distributor device" which is inserted into an ejection device with which the piston is inserted into the cylinder and thus the bone cement can be filled into a cavity in the bone tissue.
  • the known device consists of a vessel, preferably made of metal, with a base and a lid, which is attached by means of screws attached to the top of the vessel.
  • the bottom is in one piece with connected to the vessel and has a protruding edge for fixing of the vessel on a rack.
  • a drive shaft Through a central opening in the lid passed through a drive shaft, the lower end of which is mounted in the ground is.
  • the radial width of the leaves is so large that their free ends during rotation against the inner jacket of the container and the manufacture effect of the plaster.
  • This known device is a so-called slow runner.
  • the drive shaft can not only by a motor, but also by hand are operated (US-PS 1 430 070).
  • the object of the invention is to remedy this create and especially in the area of smallest quantities, e.g. B. in scope of recipe mixtures, a good mix of ointments, pastes, creams, To enable gels and emulsions or the like and a decanting or filling of the recipe mixes from open mixing vessels into small dispensing vessels to avoid.
  • smallest quantities e.g. B. in scope of recipe mixtures, a good mix of ointments, pastes, creams, To enable gels and emulsions or the like and a decanting or filling of the recipe mixes from open mixing vessels into small dispensing vessels to avoid.
  • the mixing vessel is a screw jar for the preparation of recipes and the mixing tool a flat impeller with a crescent shape in its plane of rotation trained flat impellers, the outer areas as outer Friction surfaces and their upper and lower areas as upper and lower Friction surfaces are formed, the height of the flat paddle and the height of the screw jar is dimensioned and matched to each other, that with a relative movement between the mixing vessel and the paddle the rotating outer friction surfaces in the axial direction under friction pressure rest on the inner jacket of the mixing vessel and the upper friction surface on the Inner surface of the lid and the lower friction surface on the inner surface of the Soil can be applied under friction pressure.
  • Screw jars have been the common name in pharmacies for ages Ointment storage or ointment delivery containers, preferably in the area of recipe blends.
  • Today the screw jars are made of plastic and are made with contents of 10, 20, 30, 50, 75, 100, 150, 200, 250 and 300 or 500 ml in the trade. Jars may only be used once as pharmaceutical packaging issued and not taken back and refilled. They are disposable containers.
  • the recipe components are mixed in a closed system according to the invention with a substantial absence of air. Transferring the ointments, Pastes, creams, gels, emulsions or the like from a large mixing vessel in small dispensers.
  • the mixing vessel is also a dispensing vessel but also storage vessel.
  • the screw jar is further developed in the inventive manner according to claim 6 . These measures make it possible to use the jar not only as a storage and dispensing container, but above all as a mixing container for recipe mixtures.
  • the jar body is a circular cylinder, this can be the external thread for the screw cap opposite end a bottom opening and one Have inner ring. Then a floor can be moved in the jar body be arranged. It is thus possible to go through the contents of the jar the central opening of the screw cap or through an applicator push the screw jar out. Within the scope of the invention it is possible Different applicators using a clip connection in the central opening the screw cap. With the sliding floor If necessary, a volume compensation can also be established if the amount of a recipe mixture is smaller than the volume of the screw jar.
  • the jar according to the invention with the movable bottom ensures for the first time the requirement according to ⁇ 13 of ApBetr0 also for an ointment jar, that the quality of the medicinal product placed on the market "is not is more than inevitably compromised ".
  • Fig. 1 shows in cross section a screw jar 1 with a Jar body 2, which is designed as a circular cylinder. He has an inner jacket 3 with a diameter 4. The upper area of the outer shell 5 of the jar body 2 is with provided with an external thread 8.
  • a bottom opening 6 is arranged in the bottom of the jar body 2, which is enclosed by an inner ring 7.
  • a sliding floor 9 which has an inner surface 11 and the diameter 10 of the diameter 4 of the Corrugated body corresponds.
  • the sliding floor 9 is slightly arched and has an outer edge 12 which in one Slide ring 13 passes over.
  • the floor 9 can be done without difficulty be pushed up through the bottom opening 6. Its outer edge 12 seals against the inner jacket 3 of the jar body 2 from.
  • On the external thread 8 of the jar body 2 is a Screwed cover 26 screwed on, the edge 27 with an internal thread 28 is provided.
  • the screw cap 26 is with a Central opening 30 which has an inner diameter 31st having.
  • the central opening is through a plug 32 closable, which has a central longitudinal opening 33, which ensures elasticity. He is still provided with a handle 34 and by means of a Connecting strip 35 attached to the screw cap 26.
  • Two opposite holes 23 in the lower region of the jar body 2 are for locking or fastening the jar body provided on a frame 50.
  • Fig. 2 shows the cross section through the screw cap 26, wherein the closure plug 32 seals the central opening 30.
  • Fig. 3 is a second embodiment of a jar body 15 shown.
  • the inner jacket 16 and the outer jacket 18 are frustoconical for manufacturing reasons educated.
  • the taper of the jar body 15 to solid bottom 19 is indicated by the angle 22.
  • the average diameter of the inner jacket 16 is designated 17.
  • the solid bottom has a curved inner surface 20 on.
  • the shape of the floor is the lower surface area of the Adjusted mixing tool.
  • the external thread 21 in the upper region of the outer jacket 18 corresponds to the internal thread 28 in the edge 27 of the screw cap 26.
  • Two opposite holes 24 in the lower area of the Jar body 15 are for locking or fastening of the jar body is provided on a frame 50.
  • FIG. 4 shows the section along the line IV-IV in FIG. 1 with a top view of the stirring tool.
  • FIG. 1 are for better explanation the areas 37 cut out in the wall of the jar body. This is indicated by cross hatching. These cut out areas 37 are also shown in FIG. 4, to demonstrate that the trailing wing parts 59 of the paddle stirrer 56 in the extended state a distance 60 between the friction surfaces 58, the larger is the inner diameter 4 or the mean diameter 17 of the jar body 2 or 15. As said, the cut out Areas 37 are shown for demonstration purposes only.
  • the blade stirrer 56 has half-moon-shaped stirring blades 57, which end in wing parts 59 lagging when rotating.
  • the Wing parts 59 have been retracted so far into the interior of the jar, that it rotates due to the inertia of the mix the friction surfaces 58 reinforced on the inner walls 3, 16 of the Press on screw jars 1, 14.
  • FIG. 5 shows a cross section along the line V-V in FIG. 4. Especially in the transition area between the hub 62 of the The blade stirrer and the stirring blades 57 is the cross section according to Kind of propeller profiles 61 formed, which the Mix when mixing on the inner surface 11 of the slidable Soil 9 or the inner surface 20 of the solid bottom 19 is pressed.
  • the paddle 56 is in cross section along the Line I-I shown in Fig. 4. You can clearly see how the friction surfaces 58 abut the inner casing 3 of the jar body 2.
  • the wing stirrer 56 sits at the end of a drive shaft 54, which is guided through the central opening 30 of the screw cap 26 is. As a result, the elasticity of the impeller 57 Mixing process neither by the frustoconical formation of the Inner jacket 16 of the screw jar 1, 14 is not affected.
  • the lower regions 64 of the impeller 56 are in the Shape of the inner surface 11 and 20 adapted.
  • the top Areas 63 of the paddle 56 are the inner surface 29 of the Adjusted screw cap 26.
  • FIG. 6 shows applicators that according to the requirement of DAB for the application of ointments for the invention Screw jar have been developed.
  • 6a shows the Cross section of suitable applicators (hub and ear 38, rectum 39, 40 and vagina 41).
  • 6e shows the connection of an applicator 42 with the screw cap 26. The connection happens by means of a clip connection 44. Part of this clip connection is the central opening 30 in the screw cap 26.
  • everyone Applicator 38 to 42 has a lower area 45, whose diameter 46 is the diameter 31 of the central opening 30 in the screw cap 26 corresponds.
  • Each applicator 38 to 42 ends with an end ring 47, above which a clip bead 48 is arranged. The distance between the end ring 47 and the clip bead 48 corresponds to the thickness of the screw cap 26.
  • Fig. 7 shows schematically an agitator 49 through which the Paddle stirrer 56 can be operated.
  • a stand plate 51 On a stand plate 51 is a stand 52 on which a speed-controllable Electric motor 53 is attached. This can be done using a Handle 55 moves up and down in a conventional manner be, as the double arrow next to the handle 53 indicates.
  • Paddle stirrer 56 At the end of the drive shaft 54 is described Paddle stirrer 56 connected.
  • the stirring process can be done while the operator holding the screw jar 1, 14 in his hand and slowly moved up and down relative to the paddle stirrer, not shown.
  • the Screw jars can also be attached to a frame 50 and the electric motor 53 by means of the handle 55 or automatically be guided up and down.
  • the screw cap 26 unscrewed from the screw jar 1, 14. Then either the drive shaft 54 from the chuck of the electric motor 53 loosened and the screw cap from the drive shaft 54 be removed. But it is also possible to use the paddle stirrer 56 from the end of the drive shaft 54 to release the cover 26 deduct from the drive shaft 54.
  • the central opening 30 of the screw cap either closed by the stopper 32, or it already becomes one of those shown in FIG. 6 Applicators inserted into the central opening 30 and with a Cap 43 closed.
  • the applicators snap so tight in the screw cap that when applying Do not slip ointments, but easy to replace if necessary are.
  • the screw jars can be of any known per se Material.
  • the paddle stirrers can Spring steel or made of nylon. Leave both materials elastic deformation.
  • the ascending and descending during the stirring process are particularly advantageous Friction surfaces 58 at the end of the impeller 57, because of the larger distance 60 and the crescent-shaped wing curvature kept under tension and to the inner coats the jar body is pressed and depending on the Rotation speed, because of the special design of the Wing ends, increase the friction pressure yourself.
  • screw jars 1, 14 with volumes of 10, 20, 30, 50, 75, 100, 150, 200, 250, 300 or 500 ml are used.
  • the advantage is that the rotation of the paddle Friction surfaces 58, 63, 64 due to the friction pressure in close contact come with the inside surfaces of the screw jar. Hereby it is possible to detect extremely viscous admixtures and distribute homogeneously in the mix.
  • the invention allows that in the stirring or mixing device according to the substances to be mixed (e.g. powder or non-solid ointment mixtures) also differently shaped Mixing tools are used.
  • substances to be mixed e.g. powder or non-solid ointment mixtures
  • also differently shaped Mixing tools are used.
  • the invention allows that, for example Ointment usually weighed all the ingredients into the jar at the same time can be. Generally will be dependent of the set speed of the electric motor 53 in less achieved extremely homogeneous mixing results in one minute.
  • the paddle mixer taken.
  • the mixing vessel is through the screw cap 26 closed. If necessary, an applicator can be used become. Otherwise the plug 32 in the Central opening 30 pressed in, after which the recipe mixture is ready for delivery.
  • the stirring tool 56 the only tool that needs to be cleaned.

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mixers Of The Rotary Stirring Type (AREA)
  • Closures For Containers (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Cosmetics (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Claims (12)

  1. Système pour la production de pommades, crèmes, gels ou émulsions pharmaceutiques et/ou cosmétiques avec ou sans l'addition de composants solides dans un récipient-mélangeur (1,14) fermé par un couvercle (26), comportant un agitateur (56) actionné par un électro-moteur (53) par l'intermédiaire d'un arbre de commande (54) passé à travers d'une ouverture centrale (30) prévue dans le couvercle (26), l'agitateur (56) ayant des ailes-agiter flexibles des zones extérieures desquels comportent des surfaces extrèmes joignant pendant la rotation la surface intérieure (9, 16) du récipientmélangeur (1,14),
    caractérisé en ce
    que le récipient-mélangeur est une cruche filetée (1,14) pour préparer des formules, et que l'agitateur est un agitateur à l'ailes (56) plat ayant des ailes (57) plattes formées croissant dans son plan de rotation, les régions extérieures desquelles sont formées comme surfaces de friction (58) et les régions supérieures et inférieures desqulles sont formées comme surfaces de friction (63,64) supérieures et inférieures, l'hauteur de l'agitateur (56) plat and l'hauteur de la cruche filetée (1,14) étant dimensionnée et ajustée l'un à l'autre tellement qu'au movement relatif entre le récipient-mélangeur (1,14) et l'agitateur (56) dans la direction axiale les surfaces de friction (58) extérieures en rotation, sous pression de friction, joignent la surface intérieure (3,16) de la cruche filetée (1,14) et la surface de friction (63) supérieure joigne la surface intérieure (19) du couvercle (26) et la surface de friction (64) inférieure joigne la surface intérieure (11,20) du fond (9,19) sous pression de friction.
  2. Agitateur à l'ailes pour la production de pommades, crèmes, gels ou émulsions pharmaceutiques et/ou cosmétiques avec ou sans l'addition de composants dans un récipient-mélangeur (1,14) fermé par un couvercle (26), actionné par un électro-moteur (57) par l'intermédiaire d'un arbre de commande (54) passé à travers d'une ouverture centrale (30) prévue dans le couvercle (26), l'agitateur ayant, dans le plan de rotation, des ailes-agiter (57) croissantes, les régions extérieures desquelles sont formées comme surfaces de friction (58) extérieures, et les régions supérieures et inférieures desquelles sont formées comme surfaces de friction (63,64) supérieures et inférieures, l'hauteur de l'agitateur (56) plat and l'hauteur du récipient-mélangeur (1,14) étant dimensionnée et ajustée l'un à l'autre tellement qu'au movement relatif entre le récipient-mélangeur (1,14) et l'agitateur (56) dans la direction axiale les surfaces à friction (58) extérieures en rotation, sous pression de friction, joignent la surface intérieure (3,16) du récipientmélangeur (1,14) et la surface de friction (63) supérieure joigne la surface intérieure (29) du couvercle (26) et la surface de friction (64) inférieure joigne la surface intérieure (11,20) du fond (9,19) sous pression de friction et que la distance (60) entre les surfaces de friction (58) opposées extérieures dans la condition ouverte des ailes (57) en forme croissante est plus large que le diamètre (7,17) de la cruche filetée (1,14), et que la région intérieure des ailes (57) est assise à un moyeu (62) fixé à l'extrémité inférieure de l'arbre de commande (54), et que la région de transition entre le moyeu (62) et le boutant en form d'arche de chaque aile (57) est en forme d'un profile de hélice aérienne (61).
  3. Agitateur à l'ailes selon la revendication 2,
    caractérisé en ce
    que le profil d'hélice aérienne (61) à l'aile (57) avec la surface de friction (63) supérieure est formé tellement que pendant la rotation la matière à mélanger est mouvée vers le fond (9, 19) de la cruche filetée et que le profil d'hélice aérienne (61) à l'aile d'agitateur (57) avec la surface de friction inférieure (64) est formé tellement que la matière à mélanger pendant la rotation est mouvée vers le couvercle fileté (26).
  4. Agitateur à l'ailes selon les revendications 2 et 3,
    caractérisé en ce
    qu'il comporte deux ailes-agiter (57).
  5. Agitateur à l'ailes selon les revendications 2 à 4,
    caractérisé en ce
    que les régions extrêmes des surfaces de friction extérieures (58) arrières pendant la rotation sont distantes de la surface intérieure (3,16) de la cruche filetée (1,14) et saillent dans l'intérieur du corps du récipient de la cruche (2,15).
  6. Cruche filetée (1,14) fermée par un couvercle (26) pour la production de pommades, crèmes, gels ou émulsions pharmaceutiques et/ou cosmétiques avec ou sans l'addition de composants solides le couvercle (26) de laquelle est prévu d'une overture centrale (30) pour passer un arbre de commande (54) commandé par un électro-moteur (53) pour un agitateur à l'ailes (56) prévu d'ailes-agiter (57) plattes les régions extérieures desquelles sont formées comme surfaces de friction qui joignent pendant la rotation la surface intérieure (9,16) de la cruche filetée (1,14), et les régions supérieures et inférieures desquelles sont formées comme surface de friction (63,64) supérieure et inférieure, l'haueur de l'agitateur à l'ailes (56) et la hauteur de la cruche filetée (1,14) étant tellement dimensionné et ajustée l'un à l'autre qu'au movement relatif entre la cruche filetée (1,14) et l'agitateur (56) dans la direction axiale les surfaces de friction (58) extérieures en rotation, sous pression de friction, joignent la surface intérieure (3,16) de la cruche filetée (1,14) et les surfaces de friction (63) supérieures joignent la surface intérieure (29) du couvercle (26), et les surfaces de friction (64) inférieures joignent la surface intérieure (11, 20) du fond (9, 19) sous pression de friction, que la cruche filetée peut étre utilisée non seulement comme récipient-mélangeur mais également comme distributeur pour des mélanges de formule, que le corps de cruche (2) est en forme de cylindre circulaire ou que la surface intérieure (16) et la surface extérieure (18) du corps de cruche (14,15) dans une manière tronconique contracturent du couvercle (26) vers le fond (19) solide et que le couvercle de cruche est en forme de couvercle fileté (26), et que l'ouverture centrale (30) après terminaison du procès-mélanger et après l'élimination de l'arbre de commande (54) est fermée par un bouchon (32; 38-43), et que la forme des surfaces intérieures (11,20) du fond (9, 19) solide ou déplacé conforme aux surfaces de friction inférieures (64) du mélangeur (56) et la forme de la surface intérieure (29) du couvercle fileté (26) conforme à la surface de friction (63) supérieure de l'agitateur.
  7. Cruche filetée selon la revendication 6,
    caractérisé en ce
    que l'extrémité de la cruche filetée (1) formée comme cylindre circulaire opposant le couvercle fileté (26) comporte une ouverture du fond (6), et que le fond est formé comme fond (9) déplacable dans la cruche filetée (1).
  8. Cruche filetée selon les revendictions 6 et 7,
    caractérisé en ce
    que l'ouverture du fond (6) est prévue d'un anneau interne (9).
  9. Cruche filetée selon les revendications 6 à 8,
    caractérisé en ce
    que le bord extérieur (12) du fond déplacable passe à un anneau de glissement (13) inférieur.
  10. Cruche filetée selon les revendications 6 à 9,
    caractérisé en ce
    que l'ouverture centrale (30) prévue dans le couvercle fileté (26) est formé pour monter des applicateurs (38-42) differents.
  11. Cruche filetée selon la revendication 10,
    caractérisé en ce
    que l'ouverture centrale (30) prévue dans le couvercle fileté (26) est formée comme partie d'un raccordement de clip (44) pour monter des applicateurs (38-42) différents la région arrière (45) desquels d'un diamètre (46) correspondant au diamètre (31) de l'ouverture centrale (30) est prévue d'un anneau de fin (47) et d'un talon de clip (48).
  12. Cruche filetée selon l'une des revendications 6 à 11,
    caractérisé en ce
    qu'un obturateur (32) attaché au couvercle fileté (26) est prévu pour fermer l'ouverture centrale (30).
EP93909978A 1992-05-16 1993-05-13 Systeme pour la production de pommades pharmaceutiques et/ou cosmetiques ou analogues directement dans le distributeur Expired - Lifetime EP0594820B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4216252 1992-05-16
DE4216252A DE4216252C2 (de) 1992-05-16 1992-05-16 Anordnung mit einem Rührwerk zur Mischung von pharmazeutischen und/oder kosmetischen Salben, Pasten, Cremes, Geleen oder Emulsionen
PCT/EP1993/001194 WO1993023156A1 (fr) 1992-05-16 1993-05-13 Recipient a vis servant de distributeur de liniments pharmaceutiques et/ou cosmetiques ou analogues, produits a l'aide d'un melangeur-agitateur

Publications (2)

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EP0594820A1 EP0594820A1 (fr) 1994-05-04
EP0594820B1 true EP0594820B1 (fr) 2000-01-19

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EP93909978A Expired - Lifetime EP0594820B1 (fr) 1992-05-16 1993-05-13 Systeme pour la production de pommades pharmaceutiques et/ou cosmetiques ou analogues directement dans le distributeur

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Country Link
US (1) US5397178A (fr)
EP (1) EP0594820B1 (fr)
JP (1) JP3405542B2 (fr)
AT (1) ATE188887T1 (fr)
DE (2) DE4216252C2 (fr)
ES (1) ES2145048T3 (fr)
GR (1) GR3033283T3 (fr)
PT (1) PT594820E (fr)
WO (1) WO1993023156A1 (fr)

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US10966506B2 (en) 2018-10-30 2021-04-06 Rea Innovations, Inc. Dual-piston appliance for processing of cosmetic formulations
US11497692B2 (en) 2019-10-15 2022-11-15 Rea Innovations, Inc. Systems and methods for blending solid-shell cosmetic ingredient capsules and blendable cosmetic ingredient capsules
USD986498S1 (en) 2020-03-04 2023-05-16 Rea Innovations, Inc. Cosmetic appliance
US11660578B2 (en) 2019-10-15 2023-05-30 Rea Innovations, Inc. Systems and methods for blending solid-shell cosmetic ingredient capsules and blendable cosmetic ingredient capsules

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Publication number Priority date Publication date Assignee Title
US10966506B2 (en) 2018-10-30 2021-04-06 Rea Innovations, Inc. Dual-piston appliance for processing of cosmetic formulations
US11497692B2 (en) 2019-10-15 2022-11-15 Rea Innovations, Inc. Systems and methods for blending solid-shell cosmetic ingredient capsules and blendable cosmetic ingredient capsules
US11660578B2 (en) 2019-10-15 2023-05-30 Rea Innovations, Inc. Systems and methods for blending solid-shell cosmetic ingredient capsules and blendable cosmetic ingredient capsules
US12011493B2 (en) 2019-10-15 2024-06-18 Rea Innovations, Inc. Systems and methods for blending solid-shell cosmetic ingredient capsules and blendable cosmetic ingredient capsules
USD986498S1 (en) 2020-03-04 2023-05-16 Rea Innovations, Inc. Cosmetic appliance

Also Published As

Publication number Publication date
DE4216252C2 (de) 1994-05-26
GR3033283T3 (en) 2000-09-29
ES2145048T3 (es) 2000-07-01
WO1993023156A1 (fr) 1993-11-25
US5397178A (en) 1995-03-14
EP0594820A1 (fr) 1994-05-04
JP3405542B2 (ja) 2003-05-12
DE4216252A1 (de) 1993-11-18
ATE188887T1 (de) 2000-02-15
PT594820E (pt) 2000-07-31
JPH06509263A (ja) 1994-10-20
DE9321387U1 (de) 1997-12-11

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