EP0218840A2 - Pulvérisateur pour matériaux fluidiques - Google Patents

Pulvérisateur pour matériaux fluidiques Download PDF

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Publication number
EP0218840A2
EP0218840A2 EP86111115A EP86111115A EP0218840A2 EP 0218840 A2 EP0218840 A2 EP 0218840A2 EP 86111115 A EP86111115 A EP 86111115A EP 86111115 A EP86111115 A EP 86111115A EP 0218840 A2 EP0218840 A2 EP 0218840A2
Authority
EP
European Patent Office
Prior art keywords
pump
discharge device
housing
discharge
piston
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP86111115A
Other languages
German (de)
English (en)
Other versions
EP0218840B1 (fr
EP0218840A3 (en
Inventor
Lothar Graf
Karl-Heinz Fuchs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aptar Radolfzell GmbH
Original Assignee
Erich Pfeiffer GmbH
Ing Erich Pfeiffer GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erich Pfeiffer GmbH, Ing Erich Pfeiffer GmbH filed Critical Erich Pfeiffer GmbH
Publication of EP0218840A2 publication Critical patent/EP0218840A2/fr
Publication of EP0218840A3 publication Critical patent/EP0218840A3/de
Application granted granted Critical
Publication of EP0218840B1 publication Critical patent/EP0218840B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/02—Membranes or pistons acting on the contents inside the container, e.g. follower pistons

Definitions

  • the invention relates to a discharge device for flowable media, in particular an atomizer, with a media store provided in a housing with a thrust piston pump, which has a pump piston which is displaceably guided on a piston track of a pump cylinder between an initial position and a pump stroke end position, and a pump piston which is formed by the pump cylinder Has discharge opening of the device via an outlet channel connected pump chamber in the form of a metering chamber determining the discharge volume per full pump stroke.
  • discharge devices of this type have a media storage which is spatially separate from the pump chamber, which is connected to the pump chamber via an inlet channel with an inlet valve which is generally switched on and which releases medium into the pump chamber on the return stroke of the pump piston.
  • the invention has for its object to provide a discharge device for flowable media, especially an atomizer, which is designed so that it is suitable for only a single use, that as little residual medium remains in it after use and that it with regard on the one-time use is particularly easy to set up and manufacture.
  • a discharge device of the type described in the introduction in that the entire media store of the device is formed by the pump chamber which is firmly closed opposite the pump piston and that the storage volume of this media store corresponds approximately to a single discharge volume.
  • the pump cylinder enclosing the pump chamber is therefore tightly closed except in the area in which the outlet channel is connected to it or in which the pump piston is to be used, so that it or the like as a very simple plastic structure. can be manufactured. Since the entire amount of medium stored in the discharge device is provided from the beginning in the pump chamber or in the pump cylinder, it can also be easily achieved in a simple manner that the entire stored quantity of media is discharged in the single pumping stroke.
  • the design according to the invention makes it possible to dispense with a cylinder housing with a separate cylinder cover, since the pump cylinder at its open end can be covered or closed directly by the main housing of the discharge device.
  • the pump cylinder can therefore be mounted as a freely accessible part directly on the housing, for example, which is open at the bottom and is otherwise essentially in one piece, so that it can be pushed further over the pump piston by hand from its starting position to carry out the pump stroke, and at the same time in the manner of an actuation -Push button acts. If this actuation button is in the initial position, i.e. before the dispenser is used once, completely within the housing, i.e.
  • the closed pump cylinder is only open towards the outlet channel, it does not return to its starting position after it has been actuated, but remains in the pump stroke end position, so that at the same time it forms a display device by means of which the condition of use of the discharge device can be clearly recognized.
  • an insight into the window section giving the pump cylinder can be provided in the casing of the housing, which window is expediently designed as a thumb engagement opening for actuating the discharge device.
  • the handle opposite the actuating push button for counter-holding the discharge device against the actuating pressure is to achieve a one-handed operation tion expediently formed by a finger shield, which has oppositely protruding finger contact surfaces on both sides adjacent to the central axis of the thrust piston pump, so that the index and middle fingers of the hand can be supported on them, the thumb of which rests on the push button.
  • the discharge device can be held very securely during operation and guided precisely, which is important, for example, when appropriate pharmaceuticals are discharged into a nostril. Due to the design described, the discharge device can be designed to be extremely small, for example having the largest dimensions of less than 5 cm.
  • the cavities of the discharge device which are filled or to be flowed through are expediently sealed airtight, these spaces being expediently completely filled with the medium up to the closure, that is to say without any air pockets.
  • the closure can be formed by an outlet valve which only opens at excess pressure in the pump chamber and is otherwise tightly closed, in particular a ball hose valve according to DE-OS 29 02 624, to which reference is given here for further details, in particular with regard to the simple and safely functioning structure is taken.
  • a closure which represents a predetermined breaking element or which is held in the closed position by at least one predetermined breaking element could, for example, be formed by a membrane.
  • a displacement body is expediently provided in the pump chamber, which in the pump stroke end position protrudes far, preferably at least approximately up to the closure, into the outlet channel and this except for flow slots or cannulas almost completely filled.
  • the discharge device 1 has a housing 2, the base body of which is essentially only open on one side in the manner of a cap and forms a standing surface 3 lying on one plane on this open end face.
  • the housing 2 is axially symmetrical to a central axis 4 or symmetrical to two mutually perpendicular axial planes, but in the direction of one of these axial planes it has a multiple extension than in the direction of the other axial plane.
  • the base body of the housing 2 which is essentially formed by the housing shell 5 and the end wall 6 opposite the open side, is elliptical in axial view, such that in this view its outer surfaces are convexly curved outwards with different radii of curvature.
  • discharge nozzle 7 From the end wall 6 of the housing 2 is a one-piece with this, standing in the central axis 4 discharge nozzle 7, which is circular in axial view and stands over its entire outer circumference against the outer surfaces of the jacket 5, i.e. compared to the smallest diagonal dimension of the Housing body has a smaller outer diameter.
  • the discharge nozzle 7 is tapered at an acute angle to its free end and has an inner sleeve which is exposed from its free end over its entire length and which projects as a sleeve extension 8 into the housing base body beyond the inner surface of the end wall 6.
  • the inner sleeve 9 lying in the central axis 4 has at its free end an annular stop cam 10 which projects beyond its inner circumference and which forms an annular inner shoulder 11 which is substantially perpendicular to the central axis 4.
  • a cylinder container 12 engages in the inner sleeve 9 from the end facing away from the end wall 6 and is designed as a simple, cylindrical and cup-shaped container that is only open at one end.
  • the cylinder container 12 forms the entire media reservoir 13 of the discharge device 1 and encloses a pump chamber 14 which is closed at its end opposite the open end of the cylinder container 12 by a wall lying essentially at right angles to the central axis 4.
  • This end face 15 is closed by an end wall 16 which is formed in one piece with the approximately cylindrical jacket 17 of the cylinder container 12.
  • the jacket 17 has a projecting flange 18, which protrudes over its outer circumference and is continuous and continuous, which at set cylinder container 17 engages behind the inner shoulder 11 of the inner sleeve 9 and abuts against it, so that the cylinder container 12 is axially precisely fixed in its starting position.
  • the inner circumference of the cylinder container 12 or the jacket 17 forms a piston raceway 19 for a pump piston 20, which has two piston lips 21, 22 converging at opposite acute angles and axially one behind the other for guidance on the piston raceway 19.
  • the pump piston 20 is designed as a hollow ring piston which is provided at the end of a hose section 24 of a piston tappet 23 which is formed in one piece with it, the other section of the piston tappet 23 being formed by the sleeve extension 8.
  • the end of the hose section 24 remote from the pump piston 20 is securely inserted and axially struck in an enlarged bore section of the associated free end of the sleeve extension 8.
  • the section 24 and the sleeve extension 8 form an outlet channel 25 which lies entirely within the piston rod in the central axis 4 and which connects the pump chamber 14 to a discharge opening 26 leading to the outside at the free end of the discharge nozzle 7 with the interposition of an outlet valve 27.
  • valve body 28 of this outlet valve 27, formed by a ball, is tightly enclosed by the associated, elastically expandable longitudinal section of the hose section 24, this longitudinal section in the region of a section of the bore of the sleeve which is slightly enlarged compared to its outer diameter set 8 lies, which abuts on both sides of the valve body 28 on the outer circumference of the hose section 24 and therefore supports this on both sides of the valve body 28.
  • a cup-shaped nozzle cap 31 with its jacket is inserted into an annular groove 30 lying in the central axis 4, which has an atomizer nozzle 32 forming the discharge opening 26 in its exposed front wall, which is slightly set back from the end face of the discharge nozzle 7.
  • annular groove 30 Through the annular groove 30, a freely projecting support mandrel 33 is formed, which bears over the major part against the inner surface of the jacket of the nozzle cap 31, but has connecting channels for the medium leading from the remaining outlet channel 25 to the atomizing nozzle 32.
  • a displacement body 34 which stands in the central axis 4 and protrudes in the direction toward the pump piston 20 in the form of a displacement mandrel, the outside diameter of which is only slightly smaller than the inside diameter of the hose section 24 and several over the circumference distributed longitudinal slots 35 extending over its entire length.
  • the end face of the displacement body 34 lies approximately in the plane of the end face of the pump piston 20 facing it.
  • the length of the displacement body 34 corresponds almost to the length of the maximum pump stroke.
  • the pump piston 20 or its rear piston lip 22 is close to the rear end of the piston race 19, which merges into the open end surface of the cylinder container 12 via a frustoconically shaped insertion end section.
  • the cylinder container 12 With its end associated with the end wall 16, the cylinder container 12 forms a handle 36 in the manner of a pusher button, for which purpose a thumb socket 37 is provided in the outside of the end wall 16 for securely supporting the thumb tip of one hand.
  • the outside of the end wall 6 of the housing 2 forms on both sides of the discharge nozzle 7 on the long elliptical legs, a handle 38 for supporting two further fingers of the same hand, so that the handles 36, 38 have a handle for holding and actuating the discharge device 1 at the same time single hand form.
  • grip profiles in the form of, for example, parallel projecting ribs 39 are provided on the outside of the end wall 6.
  • a cutout 40 is provided symmetrically to the associated axial plane of symmetry of the housing 2, which extends with parallel side boundaries to the base 3, but the concave, arched transverse boundary thereof at a distance from the end face 6 lies, namely at most approximately up to the level of the free end face of the inner sleeve 9.
  • the width of the cutout 40 provided for the engagement with the thumb is chosen so large that the engaging thumb is guided at both side boundaries at the same time that the housing 2 can thus be put onto the thumb practically self-retaining.
  • the cylinder container 12 is pushed onto the pump piston 20 with the thumb of its associated end surface on the inner surface of the end wall 6 of the housing 2, the medium being discharged through the discharge opening 26 by opening the outlet valve 27.
  • the discharge nozzle 7 is with a closure cap 41 which completely surrounds it, which is secured by a spring catch relative to the discharge nozzle 7 and rests with its open end surface on the outer surface of the end wall 6. Before the discharge device 1 is used, this closure cap 41, which is not shown in FIGS. 1 and 3, is pulled off.
  • the support mandrel 33a is formed by a separate component 42, which has an enlarged collar 43 flattened on one side adjacent to the nozzle cap 31a.
  • This collar 43 which is widened at an acute angle to the discharge opening 26a, engages in an opening 44 in the discharge nozzle 7a which is adapted to it and which is enlarged compared to the outer diameter of the annular groove 30a and which forms a section of the outlet channel 25a.
  • the component 42 can be sprinkled from the free end into the opening 44 with the elastic widening of the discharge nozzle 7a in such a way that it is then axially secured without play and held in a centered manner.
  • the component 42 has, following the collar 43, a guide mandrel 45, the diameter of which is substantially smaller than the inner diameter of the associated section of the outlet channel 25a and which is surrounded by a valve spring 46 of the outlet valve 27a.
  • This outlet valve 27a has a valve body 28a formed by a ball and axially movable against the spring force of the valve spring 46 in the open position, to which an inner shoulder in the sleeve extension 8a is assigned as valve seat 47.
  • the exhaust valve is not as in the embodiment 1 to 3 a component of the piston unit, but a component of the housing 2a and the discharge nozzle 7a.
  • the cylinder container 12 is initially completely filled with the medium to be discharged, after which the pump piston 20, pre-assembled with the housing 2 and the outlet valve 27, is inserted into the open end of the cylinder container 12.
  • the cylinder container 12 is pushed so far over the pump piston 20 until the outlet valve 27 opens and the enclosed air is thereby let out.
  • the recess flange 18 slides with a frustoconical widening surface provided on its outer circumference on a corresponding frustoconical counter surface provided on the inner circumference of the stop cam 18, so that the inner sleeve 9 is widened until the recess flange 18 jumps behind the inner shoulder 11.

Landscapes

  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Closures For Containers (AREA)
  • Reciprocating Pumps (AREA)
EP86111115A 1985-09-14 1986-08-12 Pulvérisateur pour matériaux fluidiques Expired - Lifetime EP0218840B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3532890 1985-09-14
DE3532890 1985-09-14

Publications (3)

Publication Number Publication Date
EP0218840A2 true EP0218840A2 (fr) 1987-04-22
EP0218840A3 EP0218840A3 (en) 1987-08-12
EP0218840B1 EP0218840B1 (fr) 1991-02-06

Family

ID=6281013

Family Applications (1)

Application Number Title Priority Date Filing Date
EP86111115A Expired - Lifetime EP0218840B1 (fr) 1985-09-14 1986-08-12 Pulvérisateur pour matériaux fluidiques

Country Status (4)

Country Link
US (1) US4921142A (fr)
EP (1) EP0218840B1 (fr)
JP (1) JPH07102873B2 (fr)
DE (3) DE8526339U1 (fr)

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0311863A2 (fr) * 1987-10-10 1989-04-19 Ing. Erich Pfeiffer GmbH & Co. KG Dispositif de distribution de fluide
FR2625981A1 (fr) * 1988-01-15 1989-07-21 Valois Sa Dispositif de pulverisation du contenu d'une ampoule cylindrique
EP0388651A2 (fr) * 1989-03-18 1990-09-26 Ing. Erich Pfeiffer GmbH Dispositif pour décharger un fluide
WO1991013281A1 (fr) * 1990-02-22 1991-09-05 Ing. Erich Pfeiffer Gmbh & Co. Kg Distributeur pour milieux
US5171219A (en) * 1989-06-08 1992-12-15 Sumitomo Pharmaceuticals Co., Ltd. Pharmaceutical preparation administrator
WO1993000172A1 (fr) * 1991-06-26 1993-01-07 Valois (Societe Anonyme) Dispositif pour projeter une dose predeterminee d'un produit fluide, et son procede de remplissage
FR2678906A1 (fr) * 1991-07-10 1993-01-15 Valois Dispositif pour projeter une dose predeterminee d'un produit fluide, et son procede de remplissage.
GB2262137A (en) * 1991-11-16 1993-06-09 Pfeiffer Erich Gmbh & Co Kg Dispenser for media
WO1993024164A1 (fr) * 1992-06-03 1993-12-09 Astra Aktiebolag Agencement et procede de distribution d'un produit de pulverisation nasale sans conservateur, et de preparations similaires
GR1001447B (el) * 1992-12-08 1993-12-30 Ron Poulenk Rorer Anonymos Emp Φαρμακευτικά προιόντα για την χορήγηση καλτσιτονίνης ενδορινικώς.
US5307953A (en) * 1991-12-03 1994-05-03 Glaxo Group Limited Single dose dispenser having a piercing member
DE19753147A1 (de) * 1997-11-29 1999-06-02 Pfeiffer Erich Gmbh & Co Kg Spender mit manuell betätigbarer Ausbringeinrichtung
US6000580A (en) * 1992-06-03 1999-12-14 Astra Aktielbolag Device for dispensing preservative-free nasal sprays and similar preparations
CN110180701A (zh) * 2016-09-14 2019-08-30 固瑞克明尼苏达有限公司 流体喷射器中的活塞-阀接合

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US5257726A (en) * 1985-08-14 1993-11-02 Ing. Erich Pfeiffer Gmbh & Co. Kg Dispenser for flowable media
DE4005527C2 (de) * 1990-02-22 2003-04-30 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien mit einer handbetätigten Pumpe
DE4008068A1 (de) * 1990-03-14 1991-09-19 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer medien
DE4030530A1 (de) * 1990-09-27 1992-04-02 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer medien
GB9114080D0 (en) * 1991-06-28 1991-08-14 Weston Terence E Atomising valve
DE4329707C2 (de) * 1993-09-02 1996-04-25 Innocos Gmbh Zerstäubungsaufsatz für einen Flüssigkeitsbehälter
DE4412041A1 (de) * 1994-04-08 1995-10-12 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für fließfähige Medien, insbesondere für den Austrag in nur einem Hub
DE19525734A1 (de) * 1995-07-14 1997-01-16 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für fließfähige Medien, insbesondere für den Austrag in nur einem Hub
FR2746676B1 (fr) * 1996-04-02 1998-05-22 Valois Dispositif de distribution d'une dose unique de produit fluide
DE19704849B4 (de) * 1997-02-08 2011-02-17 Ing. Erich Pfeiffer Gmbh Austragvorrichtung für Medien
DE19831526A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien sowie Verfahren zur Herstellung eines Spenders
US6732955B1 (en) 1999-07-08 2004-05-11 Ing. Erich Pfeiffer Gmbh Dispenser for media and method for producing a dispenser
DE19940236A1 (de) * 1999-08-25 2001-03-08 Pfeiffer Erich Gmbh & Co Kg Spender mit manuell betätigbarer Ausbringeinrichtung
DE19944209A1 (de) * 1999-09-15 2001-03-22 Pfeiffer Erich Gmbh & Co Kg Spender zum ggf. zerstäubten Ausbringen eines insbesondere flüssigen Mediums aus einem Behältnis
DE10006368A1 (de) 2000-02-12 2001-08-16 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
DE10036594A1 (de) * 2000-07-27 2002-02-07 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
DE10050982A1 (de) * 2000-10-16 2002-04-18 Pfeiffer Erich Gmbh & Co Kg Spender und Verfahren zum Austragen von Medien
DE10130368A1 (de) * 2001-06-23 2003-01-16 Pfeiffer Erich Gmbh & Co Kg Spender zum Austragen eines fluidischen Mediums
FR2832329B1 (fr) * 2001-11-20 2004-11-19 Valois Sa Dispositif de pulverisation a actionnement lateral
NZ546659A (en) * 2002-05-09 2008-02-29 Glaxo Group Ltd A fluid dispensing device, including pre-loaded actuating means, for use as a nasal inhaler
GB0305583D0 (en) * 2003-03-11 2003-04-16 Glaxo Group Ltd A fluid dispensing device
GB0405477D0 (en) * 2004-03-11 2004-04-21 Glaxo Group Ltd A fluid dispensing device
PL1699512T3 (pl) * 2003-11-03 2012-11-30 Glaxo Group Ltd Urządzenie do dozowania płynów
BRPI0508578B8 (pt) * 2004-03-10 2021-05-25 Glaxo Group Ltd inalador pressurizado de dose medida
FR2868709B1 (fr) * 2004-04-08 2006-06-23 Rexam Dispensing Systems Sas Distributeur sans reprise d'air pour la delivrance de faibles doses de produits liquides et, en particulier, de produits cosmetiques ou pharmaceutiques
FR2884157B1 (fr) * 2005-04-08 2007-07-06 Airlessystems Soc Par Actions Tete de distribution
GB0507224D0 (en) * 2005-04-09 2005-05-18 Glaxo Group Ltd A fluid dispensing device
DE102009017459B4 (de) * 2009-04-02 2017-02-23 Aptar Radolfzell Gmbh Austragvorrichtung
WO2011026198A1 (fr) * 2009-09-07 2011-03-10 Mk International Pty Ltd Pompe pour pulvérisation nasale
DE102013001571B4 (de) * 2013-01-30 2021-02-04 Aero Pump Gmbh Abgabevorrichtung für Fluide aus einem Fluidbehälter
FR3066921B1 (fr) * 2017-06-06 2022-06-03 Aptar France Sas Dispositif de distribution de produit fluide ou pulverulent.
USD828543S1 (en) * 2017-08-01 2018-09-11 Khanquer Pharma, Inc. Dual nostril nasal spray device

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EP0021123A1 (fr) 1979-06-08 1981-01-07 Hoechst Aktiengesellschaft Pulvérisateur

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0311863A2 (fr) * 1987-10-10 1989-04-19 Ing. Erich Pfeiffer GmbH & Co. KG Dispositif de distribution de fluide
JPH01139376A (ja) * 1987-10-10 1989-05-31 Ing Erich Pfeiffer Gmbh & Co Kg 吐出装置
EP0311863A3 (en) * 1987-10-10 1990-01-24 Ing. Erich Pfeiffer Gmbh & Co. Kg Device for dispersing a fluid
US4946069A (en) * 1987-10-10 1990-08-07 Ing. Erich Pfeiffer Gmbh & Co. Kg Dispenser for manually discharging flowable media
FR2625981A1 (fr) * 1988-01-15 1989-07-21 Valois Sa Dispositif de pulverisation du contenu d'une ampoule cylindrique
EP0388651A2 (fr) * 1989-03-18 1990-09-26 Ing. Erich Pfeiffer GmbH Dispositif pour décharger un fluide
EP0388651A3 (fr) * 1989-03-18 1991-05-29 Ing. Erich Pfeiffer GmbH Dispositif pour décharger un fluide
US5171219A (en) * 1989-06-08 1992-12-15 Sumitomo Pharmaceuticals Co., Ltd. Pharmaceutical preparation administrator
WO1991013281A1 (fr) * 1990-02-22 1991-09-05 Ing. Erich Pfeiffer Gmbh & Co. Kg Distributeur pour milieux
WO1993000172A1 (fr) * 1991-06-26 1993-01-07 Valois (Societe Anonyme) Dispositif pour projeter une dose predeterminee d'un produit fluide, et son procede de remplissage
FR2678906A1 (fr) * 1991-07-10 1993-01-15 Valois Dispositif pour projeter une dose predeterminee d'un produit fluide, et son procede de remplissage.
GB2262137A (en) * 1991-11-16 1993-06-09 Pfeiffer Erich Gmbh & Co Kg Dispenser for media
US5307953A (en) * 1991-12-03 1994-05-03 Glaxo Group Limited Single dose dispenser having a piercing member
WO1993024164A1 (fr) * 1992-06-03 1993-12-09 Astra Aktiebolag Agencement et procede de distribution d'un produit de pulverisation nasale sans conservateur, et de preparations similaires
AU674686B2 (en) * 1992-06-03 1997-01-09 Astra Aktiebolag Arrangement and method for dispensing preservative-free nasal sprays and similar preparations
US6000580A (en) * 1992-06-03 1999-12-14 Astra Aktielbolag Device for dispensing preservative-free nasal sprays and similar preparations
US6116468A (en) * 1992-06-03 2000-09-12 Astra Aktiebolag Arrangement and method for dispensing preservative-free nasal sprays and similar preparations
GR1001447B (el) * 1992-12-08 1993-12-30 Ron Poulenk Rorer Anonymos Emp Φαρμακευτικά προιόντα για την χορήγηση καλτσιτονίνης ενδορινικώς.
DE19753147A1 (de) * 1997-11-29 1999-06-02 Pfeiffer Erich Gmbh & Co Kg Spender mit manuell betätigbarer Ausbringeinrichtung
US6364166B1 (en) 1997-11-29 2002-04-02 Ing. Erich Pfeiffer Gmbh Dispenser with manually operable discharge device
CN110180701A (zh) * 2016-09-14 2019-08-30 固瑞克明尼苏达有限公司 流体喷射器中的活塞-阀接合
CN110180701B (zh) * 2016-09-14 2021-11-12 固瑞克明尼苏达有限公司 流体喷射器中的活塞-阀接合
US11371492B2 (en) 2016-09-14 2022-06-28 Graco Minnesota Inc. Piston-valve engagement in fluid sprayers

Also Published As

Publication number Publication date
DE3677451D1 (de) 1991-03-14
DE8526339U1 (fr) 1987-05-07
DE3631341C2 (de) 1997-07-10
EP0218840B1 (fr) 1991-02-06
EP0218840A3 (en) 1987-08-12
DE3631341A1 (de) 1987-04-23
JPH07102873B2 (ja) 1995-11-08
US4921142A (en) 1990-05-01
JPS6264754A (ja) 1987-03-23

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