EG21730A - Process for the synthesis of chloropurine intermediates - Google Patents

Process for the synthesis of chloropurine intermediates

Info

Publication number
EG21730A
EG21730A EG124098A EG124098A EG21730A EG 21730 A EG21730 A EG 21730A EG 124098 A EG124098 A EG 124098A EG 124098 A EG124098 A EG 124098A EG 21730 A EG21730 A EG 21730A
Authority
EG
Egypt
Prior art keywords
synthesis
chloropurine
intermediates
chloropurine intermediates
Prior art date
Application number
EG124098A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of EG21730A publication Critical patent/EG21730A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EG124098A 1997-10-14 1998-10-13 Process for the synthesis of chloropurine intermediates EG21730A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9721780.6A GB9721780D0 (en) 1997-10-14 1997-10-14 Process for the synthesis of chloropurine intermediates

Publications (1)

Publication Number Publication Date
EG21730A true EG21730A (en) 2002-02-27

Family

ID=10820547

Family Applications (1)

Application Number Title Priority Date Filing Date
EG124098A EG21730A (en) 1997-10-14 1998-10-13 Process for the synthesis of chloropurine intermediates

Country Status (44)

Country Link
US (1) US6646125B1 (ja)
EP (1) EP1023292B1 (ja)
JP (1) JP4531250B2 (ja)
KR (1) KR100543845B1 (ja)
CN (1) CN1160354C (ja)
AP (1) AP1182A (ja)
AR (1) AR014921A1 (ja)
AT (1) ATE249461T1 (ja)
AU (1) AU738462B2 (ja)
BG (1) BG64597B1 (ja)
BR (1) BR9813048B1 (ja)
CA (1) CA2306958C (ja)
CO (1) CO4980899A1 (ja)
CZ (1) CZ294482B6 (ja)
DE (1) DE69818084T2 (ja)
DK (1) DK1023292T3 (ja)
EA (1) EA003183B1 (ja)
EE (1) EE04059B1 (ja)
EG (1) EG21730A (ja)
ES (1) ES2205553T3 (ja)
GB (1) GB9721780D0 (ja)
GE (1) GEP20022679B (ja)
HK (1) HK1027807A1 (ja)
HR (1) HRP20000216B1 (ja)
HU (1) HUP0003984A3 (ja)
ID (1) ID24927A (ja)
IL (1) IL135323A (ja)
IN (1) IN184590B (ja)
IS (1) IS2195B (ja)
MA (1) MA24676A1 (ja)
MY (1) MY127470A (ja)
NO (1) NO325030B1 (ja)
NZ (1) NZ503679A (ja)
OA (1) OA11370A (ja)
PE (1) PE121899A1 (ja)
PL (1) PL188477B1 (ja)
PT (1) PT1023292E (ja)
RS (1) RS49710B (ja)
SK (1) SK285331B6 (ja)
TR (1) TR200000976T2 (ja)
TW (1) TW436488B (ja)
UA (1) UA54550C2 (ja)
WO (1) WO1999019327A1 (ja)
ZA (1) ZA989338B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ298144B6 (cs) 1997-11-27 2007-07-04 Lonza Ag Zpusob výroby (1S,4R)- nebo (1R,4S)-4-(2-amino-6-chlor-9-H-purin-9-yl)-2-cyklopenten-1-methanolu
FR2849030A1 (fr) * 2002-12-20 2004-06-25 Isochem Sa Procede de preparation des n-(2-amino-4, 6-dihalogenopyrimidin-5-yl) formamides
GB0320738D0 (en) 2003-09-04 2003-10-08 Glaxo Group Ltd Novel process
CN100465174C (zh) * 2006-06-13 2009-03-04 中国科学院上海有机化学研究所 制备光学纯阿巴卡韦的方法
KR101109476B1 (ko) * 2009-06-26 2012-01-31 현대제철 주식회사 실린더 교체용 지그장치
KR20170078868A (ko) 2010-01-27 2017-07-07 비이브 헬쓰케어 컴퍼니 항바이러스 치료
CN104672239A (zh) * 2013-11-26 2015-06-03 上海迪赛诺化学制药有限公司 一种采用一锅法制备阿巴卡韦式v中间体的工艺

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268672A (en) * 1977-02-09 1981-05-19 The Regents Of The University Of Minnesota Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
JPS6175A (ja) * 1984-03-06 1986-01-06 ブリストル−マイア−ズ　コムパニ− 神経弛緩剤、１‐フルオロフェニルブチル‐４‐（５‐ハロ‐２‐ピリミジニル）ピペラジン誘導体
IT1229531B (it) * 1988-01-20 1991-09-04 Univ Minnesota Composti nucleosidi dideossidideidrocarbociclici e formulazione farmaceutica che li contiene
US5631370A (en) * 1988-01-20 1997-05-20 Regents Of The University Of Minnesota Optically-active isomers of dideoxycarbocyclic nucleosides
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides
MY104575A (en) 1989-12-22 1994-04-30 The Wellcome Foundation Ltd Therapeutic nucleosides.
US5126452A (en) * 1990-04-06 1992-06-30 Glaxo Inc. Synthesis of purine substituted cyclopentene derivatives
US5329008A (en) * 1993-04-07 1994-07-12 Glaxo Inc. Synthesis of a 3,4-dihydroxy-1-cyclopentanylpurinone
GB9402161D0 (en) * 1994-02-04 1994-03-30 Wellcome Found Chloropyrimidine intermediates
SK284810B6 (sk) * 1997-05-13 2005-12-01 Lonza Ag Spôsob výroby (1S,4R)- alebo (1R,4S)-4-(2-amino-6-chlór-9-H- purín-9-yl)-2-cyklopentén-1-metanolu

Also Published As

Publication number Publication date
BG64597B1 (bg) 2005-08-31
AR014921A1 (es) 2001-04-11
MY127470A (en) 2006-12-29
CA2306958C (en) 2007-09-04
JP2001519432A (ja) 2001-10-23
EE04059B1 (et) 2003-06-16
TR200000976T2 (tr) 2000-11-21
AU9547698A (en) 1999-05-03
HUP0003984A2 (hu) 2001-04-28
KR20010015744A (ko) 2001-02-26
NO325030B1 (no) 2008-01-21
HRP20000216B1 (en) 2002-08-31
NZ503679A (en) 2002-09-27
PL188477B1 (pl) 2005-02-28
UA54550C2 (uk) 2003-03-17
NO20001896L (no) 2000-06-13
EA200000318A1 (ru) 2000-12-25
RS49710B (sr) 2007-12-31
DK1023292T3 (da) 2003-11-10
MA24676A1 (fr) 1999-07-01
EP1023292B1 (en) 2003-09-10
CZ20001367A3 (cs) 2000-10-11
DE69818084D1 (de) 2003-10-16
IL135323A0 (en) 2001-05-20
SK5362000A3 (en) 2001-03-12
EA003183B1 (ru) 2003-02-27
CA2306958A1 (en) 1999-04-22
IN184590B (ja) 2000-09-09
WO1999019327A1 (en) 1999-04-22
DE69818084T2 (de) 2004-07-15
CZ294482B6 (cs) 2005-01-12
IS5423A (is) 2000-03-28
KR100543845B1 (ko) 2006-01-23
YU20200A (sh) 2003-02-28
BG104352A (en) 2001-02-28
PE121899A1 (es) 1999-12-20
HUP0003984A3 (en) 2002-12-28
AP2000001790A0 (en) 2000-06-30
JP4531250B2 (ja) 2010-08-25
US6646125B1 (en) 2003-11-11
ID24927A (id) 2000-08-31
OA11370A (en) 2004-01-27
HRP20000216A2 (en) 2000-08-31
IS2195B (is) 2007-01-15
SK285331B6 (sk) 2006-11-03
CO4980899A1 (es) 2000-11-27
CN1160354C (zh) 2004-08-04
BR9813048A (pt) 2000-08-15
EP1023292A1 (en) 2000-08-02
NO20001896D0 (no) 2000-04-12
CN1281457A (zh) 2001-01-24
HK1027807A1 (en) 2001-01-23
PT1023292E (pt) 2004-02-27
IL135323A (en) 2004-07-25
BR9813048B1 (pt) 2010-07-13
ES2205553T3 (es) 2004-05-01
TW436488B (en) 2001-05-28
GEP20022679B (en) 2002-04-25
ATE249461T1 (de) 2003-09-15
PL339904A1 (en) 2001-01-15
GB9721780D0 (en) 1997-12-10
ZA989338B (en) 2000-04-13
EE200000162A (et) 2001-04-16
AU738462B2 (en) 2001-09-20
AP1182A (en) 2003-06-18

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